Engineered nanomaterial risk. Lessons learnt from completed nanotoxicology studies: potential solutions to current and future challenges

A newly developed in vitro model of the human epithelial airway barrier to study the toxic potential of nanoparticles

(2016) Barbara Rothen-Rutishauser   ALTEX-Alternatives to Animal Experimentation

Oxidative Stress Generated Damage to DNA by Gastrointestinal Exposure to Insoluble Particles

(2012) P. Moller et al.   CURRENT MOLECULAR MEDICINE

An in vitro liver model - assessing oxidative stress and genotoxicity following exposure of hepatocytes to a panel of engineered nanomaterials

(2012) Ali Kermanizadeh et al.   Particle and Fibre Toxicology

Zeta Potential and Solubility to Toxic Ions as Mechanisms of Lung Inflammation Caused by Metal/Metal Oxide Nanoparticles

(2012) Wan-Seob Cho et al.   TOXICOLOGICAL SCIENCES

Assessing the relevance of in vitro studies in nanotoxicology by examining correlations between in vitro and in vivo data

(2012) Xianglu Han et al.   TOXICOLOGY

The Evolution of the Protein Corona around Nanoparticles: A Test Study

(2011) Martin Lundqvist et al.   ACS Nano

Length-Dependent Retention of Carbon Nanotubes in the Pleural Space of Mice Initiates Sustained Inflammation and Progressive Fibrosis on the Parietal Pleura

(2011) Fiona A. Murphy et al.   AMERICAN JOURNAL OF PATHOLOGY

Induction of inflammatory responses and gene expression by intratracheal instillation of silver nanoparticles in mice

(2011) Eun-Jung Park et al.   ARCHIVES OF PHARMACAL RESEARCH

Hazard identification of particulate matter on vasomotor dysfunction and progression of atherosclerosis

(2011) Peter Møller et al.   CRITICAL REVIEWS IN TOXICOLOGY

Analysis of currently available data for characterising the risk of engineered nanomaterials to the environment and human health — Lessons learned from four case studies

(2011) Karin Aschberger et al.   ENVIRONMENT INTERNATIONAL

Detection of fullerenes (C60 and C70) in commercial cosmetics

(2011) Troy M. Benn et al.   ENVIRONMENTAL POLLUTION

Interspecies comparisons on the uptake and toxicity of silver and cerium dioxide nanoparticles

(2011) Birgit K. Gaiser et al.   ENVIRONMENTAL TOXICOLOGY AND CHEMISTRY

Particle size-dependent and surface charge-dependent biodistribution of gold nanoparticles after intravenous administration

(2011) Stephanie Hirn et al.   EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS

Exposure assessment of workplaces manufacturing nanosized TiO2and silver

(2011) Ji Hyun Lee et al.   INHALATION TOXICOLOGY

Inflammatory and genotoxic effects of nanoparticles designed for inclusion in paints and lacquers

(2011) Anne Thoustrup Saber et al.   Nanotoxicology

Size and surface charge of gold nanoparticles determine absorption across intestinal barriers and accumulation in secondary target organs after oral administration

(2011) Carsten Schleh et al.   Nanotoxicology

Fullerene C60: Inhalation Hazard Assessment and Derivation of a Period-Limited Acceptable Exposure Level

(2011) Naohide Shinohara et al.   TOXICOLOGICAL SCIENCES

Gold nanostructures: a class of multifunctional materials for biomedical applications

(2010) Claire M. Cobley et al.   CHEMICAL SOCIETY REVIEWS

A review of the in vivo and in vitro toxicity of silver and gold particulates: Particle attributes and biological mechanisms responsible for the observed toxicity

(2010) Helinor J. Johnston et al.   CRITICAL REVIEWS IN TOXICOLOGY

Review of carbon nanotubes toxicity and exposure—Appraisal of human health risk assessment based on open literature

(2010) Karin Aschberger et al.   CRITICAL REVIEWS IN TOXICOLOGY

Mutation spectrum in FE1-MUTATMMouse lung epithelial cells exposed to nanoparticulate carbon black

(2010) Nicklas Raun Jacobsen et al.   ENVIRONMENTAL AND MOLECULAR MUTAGENESIS

Metal Oxide Nanoparticles Induce Unique Inflammatory Footprints in the Lung: Important Implications for Nanoparticle Testing

(2010) Wan-Seob Cho et al.   ENVIRONMENTAL HEALTH PERSPECTIVES

Commercially manufactured engineered nanomaterials for environmental and health studies: Important insights provided by independent characterization

(2010) Heaweon Park et al.   ENVIRONMENTAL TOXICOLOGY AND CHEMISTRY

An in vitro triple cell co-culture model with primary cells mimicking the human alveolar epithelial barrier

(2010) Andrea D. Lehmann et al.   EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS

Concept of Assessing Nanoparticle Hazards Considering Nanoparticle Dosemetric and Chemical/Biological Response Metrics

(2010) Erik K. Rushton et al.   JOURNAL OF TOXICOLOGY AND ENVIRONMENTAL HEALTH-PART A-CURRENT ISSUES

Nano-silver – feasibility and challenges for human health risk assessment based on open literature

(2010) Frans M. Christensen et al.   Nanotoxicology

Nano-TiO2– feasibility and challenges for human health risk assessment based on open literature

(2010) Frans M. Christensen et al.   Nanotoxicology

Weight of Evidence approach for the relative hazard ranking of nanomaterials

(2010) Stefano Zuin et al.   Nanotoxicology

A critical review of the biological mechanisms underlying thein vivoandin vitrotoxicity of carbon nanotubes: The contribution of physico-chemical characteristics

(2010) Helinor J. Johnston et al.   Nanotoxicology

Pulmonary exposure to carbon black nanoparticles and vascular effects

(2010) Lise K Vesterdal et al.   Particle and Fibre Toxicology

Dispersion of single-walled carbon nanotubes by a natural lung surfactant for pulmonary in vitro and in vivo toxicity studies

(2010) Liying Wang et al.   Particle and Fibre Toxicology

ISDD: A computational model of particle sedimentation, diffusion and target cell dosimetry for in vitro toxicity studies

(2010) Paul M Hinderliter et al.   Particle and Fibre Toxicology

Review of fullerene toxicity and exposure – Appraisal of a human health risk assessment, based on open literature

(2010) Karin Aschberger et al.   REGULATORY TOXICOLOGY AND PHARMACOLOGY

Exposure Assessment Approaches for Engineered Nanomaterials

(2010) Linda C. Abbott et al.   RISK ANALYSIS

Surface Derivatization State of Polystyrene Latex Nanoparticles Determines both Their Potency and Their Mechanism of Causing Human Platelet Aggregation In Vitro

(2010) C. McGuinnes et al.   TOXICOLOGICAL SCIENCES

Risk assessment of engineered nanomaterials and nanotechnologies—A review

(2010) Kai Savolainen et al.   TOXICOLOGY

Biodistribution of gold nanoparticles in mouse lung following intratracheal instillation

(2009) Evaldas Sadauskas et al.   Chemistry Central Journal

Assessing exposure, uptake and toxicity of silver and cerium dioxide nanoparticles from contaminated environments

(2009) Birgit K Gaiser et al.   Environmental Health

Modeled Environmental Concentrations of Engineered Nanomaterials (TiO2, ZnO, Ag, CNT, Fullerenes) for Different Regions

(2009) Fadri Gottschalk et al.   ENVIRONMENTAL SCIENCE & TECHNOLOGY

Role of oxidative damage in toxicity of particulates

(2009) Peter Møller et al.   FREE RADICAL RESEARCH

Size dependence of the translocation of inhaled iridium and carbon nanoparticle aggregates from the lung of rats to the blood and secondary target organs

(2009) Wolfgang G. Kreyling et al.   INHALATION TOXICOLOGY

Modest vasomotor dysfunction induced by low doses of C60 fullerenes in apolipoprotein E knockout mice with different degree of atherosclerosis

(2009) Lise K Vesterdal et al.   Particle and Fibre Toxicology

Lung inflammation and genotoxicity following pulmonary exposure to nanoparticles in ApoE-/- mice

(2009) Nicklas Jacobsen et al.   Particle and Fibre Toxicology

Identification of the mechanisms that drive the toxicity of TiO2 particulates: the contribution of physicochemical characteristics

(2009) Helinor J Johnston et al.   Particle and Fibre Toxicology

The limits of testing particle-mediated oxidative stress in vitro in predicting diverse pathologies; relevance for testing of nanoparticles

(2009) Ken Donaldson et al.   Particle and Fibre Toxicology

Nanomaterials for environmental studies: Classification, reference material issues, and strategies for physico-chemical characterisation

(2009) Vicki Stone et al.   SCIENCE OF THE TOTAL ENVIRONMENT

The Biological Mechanisms and Physicochemical Characteristics Responsible for Driving Fullerene Toxicity

(2009) Helinor J. Johnston et al.   TOXICOLOGICAL SCIENCES

Evaluating the uptake and intracellular fate of polystyrene nanoparticles by primary and hepatocyte cell lines in vitro

(2009) Helinor J. Johnston et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Moving toward exposure and risk evaluation of nanomaterials: challenges and future directions

(2009) Treye Thomas et al.   Wiley Interdisciplinary Reviews-Nanomedicine and Nanobiotechnology

Deposition, Retention, and Translocation of Ultrafine Particles from the Central Airways and Lung Periphery

(2008) Winfried Möller et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Particle size-dependent organ distribution of gold nanoparticles after intravenous administration

(2008) Wim H. De Jong et al.   BIOMATERIALS

Biodistribution of colloidal gold nanoparticles after intravenous administration: Effect of particle size

(2008) Ganeshchandra Sonavane et al.   COLLOIDS AND SURFACES B-BIOINTERFACES

Genotoxicity, cytotoxicity, and reactive oxygen species induced by single‐walled carbon nanotubes and C60fullerenes in the FE1‐Muta™Mouse lung epithelial cells

(2008) Nicklas Raun Jacobsen et al.   ENVIRONMENTAL AND MOLECULAR MUTAGENESIS

Oxidatively Damaged DNA in Rats Exposed by Oral Gavage to C 60 Fullerenes and Single-Walled Carbon Nanotubes

(2008) Janne K. Folkmann et al.   ENVIRONMENTAL HEALTH PERSPECTIVES

Exposure Modeling of Engineered Nanoparticles in the Environment

(2008) Nicole C. Mueller et al.   ENVIRONMENTAL SCIENCE & TECHNOLOGY

Nanoparticle Silver Released into Water from Commercially Available Sock Fabrics

(2008) Troy M. Benn et al.   ENVIRONMENTAL SCIENCE & TECHNOLOGY

Hazard and Risk Assessment of a Nanoparticulate Cerium Oxide-Based Diesel Fuel Additive—A Case Study

(2008) Barry Park et al.   INHALATION TOXICOLOGY

Concordance BetweenInVitroandInVivoDosimetry in the Proinflammatory Effects of Low-Toxicity, Low-Solubility Particles: The Key Role of the Proximal Alveolar Region

(2008) K. Donaldson et al.   INHALATION TOXICOLOGY

Carbon nanotubes introduced into the abdominal cavity of mice show asbestos-like pathogenicity in a pilot study

(2008) Craig A. Poland et al.   Nature Nanotechnology

Biodistribution of 1.4- and 18-nm Gold Particles in Rats

(2008) Manuela Semmler-Behnke et al.   Small

How Meaningful are the Results of Nanotoxicity Studies in the Absence of Adequate Material Characterization?

(2008) David B. Warheit   TOXICOLOGICAL SCIENCES

The impact of different nanoparticle surface chemistry and size on uptake and toxicity in a murine macrophage cell line

(2008) Martin J.D. Clift et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Oxidative stress and apoptosis induced by titanium dioxide nanoparticles in cultured BEAS-2B cells

(2008) Eun-Jung Park et al.   TOXICOLOGY LETTERS