Article
Hematology
Simone de Vries, Inge M. Krul, Michael Schaapveld, Cecile P. M. Janus, Saskia E. Rademakers, Judith M. Roesink, Marten R. Nijziel, Berthe M. P. Aleman, Flora E. van Leeuwen
Summary: Male survivors of Hodgkin lymphoma who received chest radiotherapy have a significantly increased risk of breast cancer. The risk is higher for those who received chest radiotherapy and alkylating chemotherapy compared to those who only received chest radiotherapy.
Article
Oncology
Inge M. Krul, Naomi B. Boekel, Iris Kramer, Cecile P. M. Janus, Augustinus D. G. Krol, Marten R. Nijziel, Josee M. Zijlstra, Richard W. M. van der Maazen, Judith M. Roesink, Judy N. Jacobse, Michael Schaapveld, Marjanka K. Schmidt, Annemieke W. J. Opstal-van Winden, Gabe S. Sonke, Nicola S. Russell, Berthe M. P. Aleman, Flora E. van Leeuwen
Summary: Breast cancer patients after Hodgkin lymphoma (BC-HL) have limited treatment options due to prior HL treatment and increased risk of cardiovascular disease (CVD). BC-HL patients have worse BC outcomes and higher burden of CVD compared to BC-1 patients. Clinicians need to consider the increased CVD risk when selecting BC treatment for HL survivors.
Article
Environmental Sciences
Jagadeesh Puvvula, Shannon L. Bartelt-Hunt, Balkissa S. Ouattara, Alan S. Kolok, Jesse E. Bell, Eleanor G. Rogan
Summary: This study evaluated the association between atrazine in surface and groundwater and the incidence of pediatric cancer in Nebraska watersheds over 30 years. The results suggested positive associations between watersheds with higher atrazine concentration and a higher pediatric cancer incidence rate ratio. Further research is necessary to establish the causal relationship between atrazine and pediatric cancer.
Article
Plant Sciences
Diana Alberto, Fanny Ramel, Cecile Sulmon, Gwenola Gouesbet, Ivan Couee
Summary: Herbicides and their degradation products contribute to soil pollution and have harmful consequences for soil biodiversity, ecosystem functions, and crop production sustainability. The effects of these pollutants on plant roots, as well as the interactions with environmental factors, are not fully understood.
ACTA PHYSIOLOGIAE PLANTARUM
(2022)
Review
Oncology
Joaira Bakkach, Benedetta Pellegrino, Hagar Elghazawy, Olga Novosad, Sanjit Agrawal, Mohcine Bennani Mechita
Summary: Second breast cancer is the most common solid cancer among female survivors of Hodgkin Lymphoma, with risk factors including age at treatment, dose of radiation, and extent of irradiated field. These cancers tend to develop at a younger age, are often bilateral, and have aggressive biological features and poor prognosis. While literature does not firmly answer the benefits of breast surveillance, evidence leans towards clinical benefits of early detection.
CRITICAL REVIEWS IN ONCOLOGY HEMATOLOGY
(2021)
Article
Dermatology
A. Goyal, D. O'Leary, K. Goyal, N. Rubin, M. Janakiram
Summary: Patients with mycosis fungoides (MF) have an increased risk of developing various types of cancers, with those developing non-Hodgkin lymphoma (NHL), lung cancer, and bladder cancer tending to be diagnosed at earlier stages and showing better 5-year overall survival. Regular pigmented-lesion-focused skin examinations are recommended for MF patients, along with smoking cessation counseling and ensuring up-to-date cancer screenings. Regular imaging and lab testing for second malignancy screening require further study and expert consensus.
JOURNAL OF THE EUROPEAN ACADEMY OF DERMATOLOGY AND VENEREOLOGY
(2021)
Article
Oncology
Gertraud Maskarinec, Sayaka M. Brown, Jordyn Lee, David Bogumil, Catherine Walsh, Christopher A. Haiman, Veronica Wendy Setiawan, Yurii B. Shvetsov, Loic Le Marchand
Summary: This study found an association between T2D and NHL incidence in several subgroups but not in the total population, and identified excess body weight in early life as a predictor of NHL incidence.
CANCER EPIDEMIOLOGY BIOMARKERS & PREVENTION
(2023)
Article
Oncology
Danbee Kang, Sang Eun Yoon, Dongwook Shin, Jin Lee, Yun Soo Hong, Se Kyung Lee, Jeong Eon Lee, Yeon Hee Park, Jin Seok Ahn, Eliseo Guallar, Won Seog Kim, Jungho Lee, Seok Jin Kim, Juhee Cho
Summary: Research suggests that women with breast cancer have a higher risk of developing NHL, especially in younger age groups and those receiving hormone therapy.
BLOOD CANCER JOURNAL
(2021)
Article
Oncology
F. Lennie Wong, Janie M. Lee, Wendy M. Leisenring, Joseph P. Neglia, Rebecca M. Howell, Susan A. Smith, Kevin C. Oeffinger, Chaya S. Moskowitz, Tara O. Henderson, Ann Mertens, Paul C. Nathan, Yutaka Yasui, Wendy Landier, Gregory T. Armstrong, Leslie L. Robison, Smita Bhatia
Summary: This study evaluated the outcomes and cost-effectiveness of breast cancer screening using mammography and breast magnetic resonance imaging (MRI) in female chest-irradiated childhood Hodgkin lymphoma survivors. The results showed that annual mammography screening at age 30-74 years is effective and cost-effective in this population.
JOURNAL OF CLINICAL ONCOLOGY
(2023)
Article
Environmental Sciences
Mengqi Wang, Junyu Chen, Shuhua Zhao, Jingying Zheng, Kang He, Wei Liu, Weixin Zhao, Jingze Li, Kai Wang, Yuru Wang, Jian Liu, Lijing Zhao
Summary: There is evidence of the presence of the herbicide atrazine in water sources and its harmful effects on immune and endocrine systems, as well as tumors. This study examined how atrazine impacted the development of breast cancer cells. The results showed that exposure to atrazine increased cell proliferation and tumor volume, upregulated MMPs, and suppressed immune function while promoting breast tumor development.
ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY
(2023)
Article
Oncology
Sander Roberti, Flora E. van Leeuwen, Cecile M. Ronckers, Inge M. Krul, Florent de Vathaire, Cristina Veres, Ibrahima Diallo, Cecile P. M. Janus, Berthe M. P. Aleman, Nicola S. Russell, Michael Hauptmann
Summary: The study found that mean breast dose predicts the risk of subsequent breast cancer in long-term HL survivors.
JNCI-JOURNAL OF THE NATIONAL CANCER INSTITUTE
(2022)
Article
Oncology
Rena R. Jones, Jared A. Fisher, Danielle N. Medgyesi, Ian D. Buller, Linda M. Liao, Gretchen Gierach, Mary H. Ward, Debra T. Silverman
Summary: This study investigated the relationship between environmental exposure to ethylene oxide (EtO) and the risk of breast and non-Hodgkin lymphoma cancers. The results showed an increased risk of in situ breast cancer associated with EtO-emitting facilities within 10 km, but no clear pattern of increased risk for invasive breast cancer or non-Hodgkin lymphoma.
JNCI-JOURNAL OF THE NATIONAL CANCER INSTITUTE
(2023)
Article
Oncology
Saimaitikari Abudoubari, Ke Bu, Yujie Mei, Abudukeyoumu Maimaitiyiming, Hengqing An, Ning Tao
Summary: This study explores the epidemiological trend and prognostic factors of prostate cancer patients through the latest cohort study and develops a new nomogram to predict the specific survival rate of patients. The results show significant changes in the incidence of prostate cancer with different characteristics, and the nomogram prediction model based on four factors has a high reference value in assessing patient-specific survival rate.
FRONTIERS IN ONCOLOGY
(2023)
Article
Oncology
James Yarmolinsky, Christopher I. Amos, Rayjean J. Hung, Victor Moreno, Kimberley Burrows, Karl Smith-Byrne, Joshua R. Atkins, Paul Brennan, James D. McKay, Richard M. Martin, George Davey Smith
Summary: Deucravacitinib, a selective TYK2 inhibitor, is being reviewed for the treatment of psoriasis. However, there are concerns about the safety of TYK2 inhibition due to the increased risk of lung cancer and non-Hodgkin lymphoma associated with similar medications. Genetic analysis using a loss-of-function variant in TYK2 showed an increased risk of lung cancer and non-Hodgkin lymphoma with therapeutic TYK2 inhibition. These findings have important implications for the safety assessment of deucravacitinib and other TYK2 inhibitors.
INTERNATIONAL JOURNAL OF CANCER
(2022)
Article
Environmental Sciences
Lemaan Rana, Sarah Dahlberg, Craig Steinmaus, Luoping Zhang
Summary: A systematic review and meta-analysis of human epidemiological studies revealed a potential causal link between benzene exposure and non-Hodgkin lymphoma, especially for diffuse large B-cell lymphoma.
LANCET PLANETARY HEALTH
(2021)