Histone-modifying enzymes, histone modifications and histone chaperones in nucleosome assembly: Lessons learned from Rtt109 histone acetyltransferases

Histone variants: the tricksters of the chromatin world

(2014) Catherine Volle et al.   CURRENT OPINION IN GENETICS & DEVELOPMENT

How to restore chromatin structure and function in response to DNA damage - let the chaperones play

(2014) Salomé Adam et al.   FEBS Journal

Histone H3K56 Acetylation Is Required for Quelling-induced Small RNA Production through Its Role in Homologous Recombination

(2014) Zhenyu Zhang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

PAINS: Relevance to Tool Compound Discovery and Fragment-Based Screening

(2013) Jonathan B. Baell et al.   AUSTRALIAN JOURNAL OF CHEMISTRY

A small molecule inhibitor of fungal histone acetyltransferase Rtt109

(2013) Jessica Lopes da Rosa et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Transcription Recovery after DNA Damage Requires Chromatin Priming by the H3.3 Histone Chaperone HIRA

(2013) Salomé Adam et al.   CELL

A Cul4 E3 Ubiquitin Ligase Regulates Histone Hand-Off during Nucleosome Assembly

(2013) Junhong Han et al.   CELL

Human CAF-1-dependent nucleosome assembly in a defined system

(2013) Lyudmila Y Kadyrova et al.   CELL CYCLE

Lysine Acetyltransferases CBP and p300 as Therapeutic Targets in Cognitive and Neurodegenerative Disorders

(2013) Luis Valor et al.   CURRENT PHARMACEUTICAL DESIGN

A unique epigenetic signature is associated with active DNA replication loci in human embryonic stem cells

(2013) Bing Li et al.   Epigenetics

The Carboxyl Terminus of Rtt109 Functions in Chaperone Control of Histone Acetylation

(2013) Ernest Radovani et al.   EUKARYOTIC CELL

Characterization of the Pneumocystis carinii Histone Acetyltransferase Chaperone Proteins PcAsf1 and PcVps75

(2013) Jakrapun Pupaibool et al.   INFECTION AND IMMUNITY

Compound Aggregation in Drug Discovery: Implementing a Practical NMR Assay for Medicinal Chemists

(2013) Steven R. LaPlante et al.   JOURNAL OF MEDICINAL CHEMISTRY

SIRT6 Recruits SNF2H to DNA Break Sites, Preventing Genomic Instability through Chromatin Remodeling

(2013) Debra Toiber et al.   MOLECULAR CELL

Histone chaperones in nucleosome assembly and human disease

(2013) Rebecca J Burgess et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Acetylation of Chromatin-Associated Histone H3 Lysine 56 Inhibits the Development of Encysted Artemia Embryos

(2013) Rong Zhou et al.   PLoS One

A Cell-Free Fluorometric High-Throughput Screen for Inhibitors of Rtt109-Catalyzed Histone Acetylation

(2013) Jayme L. Dahlin et al.   PLoS One

TERT promoter mutations occur frequently in gliomas and a subset of tumors derived from cells with low rates of self-renewal

(2013) P. J. Killela et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Acetylated histone H3K56 interacts with Oct4 to promote mouse embryonic stem cell pluripotency

(2013) Y. Tan et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Rtt109 Prevents Hyper-Amplification of Ribosomal RNA Genes through Histone Modification in Budding Yeast

(2013) Satoru Ide et al.   PLoS Genetics

Histone Acetyl Transferase 1 Is Essential for Mammalian Development, Genome Stability, and the Processing of Newly Synthesized Histones H3 and H4

(2013) Prabakaran Nagarajan et al.   PLoS Genetics

Histone Deacetylase Inhibitors: Design, Structure-Activity Relationships and Therapeutic Implications for Cancer

(2012) Charles Marson   Anti-Cancer Agents in Medicinal Chemistry

Selective Histone Deacetylase Inhibitors

(2012) Huili Pan et al.   Anti-Cancer Agents in Medicinal Chemistry

Codanin-1, mutated in the anaemic disease CDAI, regulates Asf1 function in S-phase histone supply

(2012) Katrine Ask et al.   EMBO JOURNAL

Histone deacetylase inhibitors: a patent review (2009 – 2011)

(2012) Vincenzo Carafa et al.   EXPERT OPINION ON THERAPEUTIC PATENTS

Chromatin Dynamics during Nucleotide Excision Repair: Histones on the Move

(2012) Salomé Adam et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Oncogene Ras/Phosphatidylinositol 3-Kinase Signaling Targets Histone H3 Acetylation at Lysine 56

(2012) Yan Liu et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Histone Chaperone Rtt106 Promotes Nucleosome Formation Using (H3-H4)2Tetramers

(2012) Ahmed Fazly et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Keratins in oral cancer: Necessity of mass spectrometry for validation of antibody based identifications

(2012) Amit Fulzele et al.   Journal of Proteomics

Chaperone-mediated acetylation of histones by Rtt109 identified by quantitative proteomics

(2012) Nebiyu Abshiru et al.   Journal of Proteomics

Histone H2A.Z Controls a Critical Chromatin Remodeling Step Required for DNA Double-Strand Break Repair

(2012) Ye Xu et al.   MOLECULAR CELL

Structural basis for recognition of H3K56-acetylated histone H3–H4 by the chaperone Rtt106

(2012) Dan Su et al.   NATURE

Intrinsic coupling of lagging-strand synthesis to chromatin assembly

(2012) Duncan J. Smith et al.   NATURE

New lysine methyltransferase drug targets in cancer

(2012) Tobias Wagner et al.   NATURE BIOTECHNOLOGY

Loss of Wild-Type ATRX Expression in Somatic Cell Hybrids Segregates with Activation of Alternative Lengthening of Telomeres

(2012) Kylie Bower et al.   PLoS One

Ordered changes in histone modifications at the core of the Arabidopsis circadian clock

(2012) J. Malapeira et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

De Novo Assembly of the Pneumocystis jirovecii Genome from a Single Bronchoalveolar Lavage Fluid Specimen from a Patient

(2012) O. H. Cisse et al.   mBio

The conformational flexibility of the C-terminus of histone H4 promotes histone octamer and nucleosome stability and yeast viability

(2012) Myrriah S Chavez et al.   Epigenetics & Chromatin

Enzymatic Transition States, Transition-State Analogs, Dynamics, Thermodynamics, and Lifetimes

(2011) Vern L. Schramm   Annual Review of Biochemistry

Small Molecule Inhibitors of Histone Acetyltransferases as Epigenetic Tools and Drug Candidates

(2011) Silviya D. Furdas et al.   ARCHIV DER PHARMAZIE

Codanin-1 mutations in congenital dyserythropoietic anemia type 1 affect HP1  localization in erythroblasts

(2011) R. Renella et al.   BLOOD

Replication-Coupled Chromatin Assembly Generates a Neuronal Bilateral Asymmetry in C. elegans

(2011) Shunji Nakano et al.   CELL

Histone H3-K56 acetylation is important for genomic stability in mammals

(2011) Jian Yuan et al.   CELL CYCLE

Cell cycle-dependent deacetylation of telomeric histone H3 lysine K56 by human SIRT6

(2011) Eriko Michishita et al.   CELL CYCLE

The sirtuin SIRT6 deacetylates H3 K56Ac in vivo to promote genomic stability

(2011) Bo Yang et al.   CELL CYCLE

Immune responses against Aspergillus fumigatus

(2011) Robert A. Cramer et al.   CURRENT OPINION IN INFECTIOUS DISEASES

Protein folding and binding: from biology to physics and back again

(2011) Michael K Gilson et al.   CURRENT OPINION IN STRUCTURAL BIOLOGY

Invasive aspergillosis in hematopoietic stem cell and solid organ transplantation

(2011) Nuran Salman et al.   Expert Review of Anti-Infective Therapy

Structure and Histone Binding Properties of the Vps75-Rtt109 Chaperone-Lysine Acetyltransferase Complex

(2011) Dan Su et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Autoacetylation of the Histone Acetyltransferase Rtt109

(2011) Brittany N. Albaugh et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Sequential Establishment of Marks on Soluble Histones H3 and H4

(2011) Francisca Alvarez et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Combining Global and Local Measures for Structure-Based Druggability Predictions

(2011) Andrea Volkamer et al.   Journal of Chemical Information and Modeling

Structural basis for MOF and MSL3 recruitment into the dosage compensation complex by MSL1

(2011) Jan Kadlec et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

T-Coffee: a web server for the multiple sequence alignment of protein and RNA sequences using structural information and homology extension

(2011) P. Di Tommaso et al.   NUCLEIC ACIDS RESEARCH

Genome-Wide Profiling of H3K56 Acetylation and Transcription Factor Binding Sites in Human Adipocytes

(2011) Kinyui Alice Lo et al.   PLoS One

Splitting of H3-H4 tetramers at transcriptionally active genes undergoing dynamic histone exchange

(2011) Y. Katan-Khaykovich et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Promoter regulation by distinct mechanisms of functional interplay between lysine acetylase Rtt109 and histone chaperone Asf1

(2011) L.-j. Lin et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Two surfaces on the histone chaperone Rtt106 mediate histone binding, replication, and silencing

(2011) R. M. Zunder et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Structure of the Rtt109-AcCoA/Vps75 Complex and Implications for Chaperone-Mediated Histone Acetylation

(2011) Yong Tang et al.   STRUCTURE

Interaction with the Histone Chaperone Vps75 Promotes Nuclear Localization and HAT Activity of Rtt109 In Vivo

(2011) Kristin M. Keck et al.   TRAFFIC

Pneumocystis cariniiExpresses an Active Rtt109 Histone Acetyltransferase

(2010) Theodore J. Kottom et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

Kinetic Mechanism of the Rtt109−Vps75 Histone Acetyltransferase−Chaperone Complex

(2010) Brittany N. Albaugh et al.   BIOCHEMISTRY

Chaperoning Histones during DNA Replication and Repair

(2010) Monica Ransom et al.   CELL

Invasive aspergillosis in pediatric patients

(2010) William J. Steinbach   CURRENT MEDICAL RESEARCH AND OPINION

Asf1b, the necessary Asf1 isoform for proliferation, is predictive of outcome in breast cancer

(2010) Armelle Corpet et al.   EMBO JOURNAL

Observations on screening-based research and some concerning trends in the literature

(2010) Jonathan B Baell   Future Medicinal Chemistry

Clinical significance and prognostic value of chromatin assembly factor-1 overexpression in human solid tumours

(2010) Sophie E Polo et al.   HISTOPATHOLOGY

Regulation of Angiogenesis by Histone Chaperone HIRA-mediated Incorporation of Lysine 56-acetylated Histone H3.3 at Chromatin Domains of Endothelial Genes

(2010) Debasree Dutta et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

SIRT1 Regulates Autoacetylation and Histone Acetyltransferase Activity of TIP60

(2010) Jiadong Wang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

New Substructure Filters for Removal of Pan Assay Interference Compounds (PAINS) from Screening Libraries and for Their Exclusion in Bioassays

(2010) Jonathan B. Baell et al.   JOURNAL OF MEDICINAL CHEMISTRY

Site-Specific Introduction of an Acetyl-Lysine Mimic into Peptides and Proteins by Cysteine Alkylation

(2010) Rong Huang et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

H4 replication-dependent diacetylation and Hat1 promote S-phase chromatin assembly in vivo

(2010) Aïda Ejlassi-Lassallette et al.   MOLECULAR BIOLOGY OF THE CELL

Replication Stress Interferes with Histone Recycling and Predeposition Marking of New Histones

(2010) Zuzana Jasencakova et al.   MOLECULAR CELL

A Role for Gcn5 in Replication-Coupled Nucleosome Assembly

(2010) Rebecca J. Burgess et al.   MOLECULAR CELL

The Histone Chaperone Nap1 Promotes Nucleosome Assembly by Eliminating Nonnucleosomal Histone DNA Interactions

(2010) Andrew J. Andrews et al.   MOLECULAR CELL

Elevated Histone Expression Promotes Life Span Extension

(2010) Jason Feser et al.   MOLECULAR CELL

Modulation of histone H3 lysine 56 acetylation as an antifungal therapeutic strategy

(2010) Hugo Wurtele et al.   NATURE MEDICINE

Human HDAC1 and HDAC2 function in the DNA-damage response to promote DNA nonhomologous end-joining

(2010) Kyle M Miller et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Catalytic activation of histone acetyltransferase Rtt109 by a histone chaperone

(2010) E. M. Kolonko et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Neural sirtuin 6 (Sirt6) ablation attenuates somatic growth and causes obesity

(2010) B. Schwer et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Histone acetyltransferase Rtt109 is required for Candida albicans pathogenesis

(2010) J. Lopes da Rosa et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Partitioning of Histone H3-H4 Tetramers During DNA Replication-Dependent Chromatin Assembly

(2010) M. Xu et al.   SCIENCE

Update on the diagnosis and treatment of Pneumocystis pneumonia

(2010) Eva M. Carmona et al.   Therapeutic Advances in Respiratory Disease

Overexpression of the Cellular DEK Protein Promotes Epithelial Transformation In vitro and In vivo

(2009) T. M. Wise-Draper et al.   CANCER RESEARCH

Screen for DNA-damage-responsive histone modifications identifies H3K9Ac and H3K56Ac in human cells

(2009) Jorrit V Tjeertes et al.   EMBO JOURNAL

The HP1α–CAF1–SetDB1-containing complex provides H3K9me1 for Suv39-mediated K9me3 in pericentric heterochromatin

(2009) Alejandra Loyola et al.   EMBO REPORTS

Activity of MGCD290, a Hos2 Histone Deacetylase Inhibitor, in Combination with Azole Antifungals against Opportunistic Fungal Pathogens

(2009) M. A. Pfaller et al.   JOURNAL OF CLINICAL MICROBIOLOGY

SWI/SNF and Asf1p Cooperate To Displace Histones during Induction of the Saccharomyces cerevisiae HO Promoter

(2009) T. Gkikopoulos et al.   MOLECULAR AND CELLULAR BIOLOGY

Histone H3 Lysine 56 Acetylation Is Linked to the Core Transcriptional Network in Human Embryonic Stem Cells

(2009) Wei Xie et al.   MOLECULAR CELL

Histone Chaperone Spt16 Promotes Redeposition of the Original H3-H4 Histones Evicted by Elongating RNA Polymerase

(2009) Adil Jamai et al.   MOLECULAR CELL

CBP/p300-mediated acetylation of histone H3 on lysine 56

(2009) Chandrima Das et al.   NATURE

The DNA-damage response in human biology and disease

(2009) Stephen P. Jackson et al.   NATURE

Chromatin remodelling beyond transcription: the INO80 and SWR1 complexes

(2009) Ashby J Morrison et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Predicting mortality from HIV-associated Pneumocystis pneumonia at illness presentation: an observational cohort study

(2009) M W Fei et al.   THORAX

Histone modifying enzymes: Structures, mechanisms, and specificities

(2008) Ronen Marmorstein et al.   Biochimica et Biophysica Acta-Gene Regulatory Mechanisms

Acetylation of Histone H3 Lysine 56 Regulates Replication-Coupled Nucleosome Assembly

(2008) Qing Li et al.   CELL

Acetylated Lysine 56 on Histone H3 Drives Chromatin Assembly after Repair and Signals for the Completion of Repair

(2008) Chin-Chuan Chen et al.   CELL

Catalysis and substrate selection by histone/protein lysine acetyltransferases

(2008) Christopher E Berndsen et al.   CURRENT OPINION IN STRUCTURAL BIOLOGY

Structure and chemistry of the p300/CBP and Rtt109 histone acetyltransferases: implications for histone acetyltransferase evolution and function

(2008) Ling Wang et al.   CURRENT OPINION IN STRUCTURAL BIOLOGY

Schizosaccharomyces pombeHst4 Functions in DNA Damage Response by Regulating Histone H3 K56 Acetylation

(2008) Devyani Haldar et al.   EUKARYOTIC CELL

Histone H3 K56 Hyperacetylation Perturbs Replisomes and Causes DNA Damage

(2008) I. Celic et al.   GENETICS

The WWOX Tumor Suppressor Is Essential for Postnatal Survival and Normal Bone Metabolism

(2008) Rami I. Aqeilan et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Chaperone Control of the Activity and Specificity of the Histone H3 Acetyltransferase Rtt109

(2008) J. Fillingham et al.   MOLECULAR AND CELLULAR BIOLOGY

HST3/HST4-dependent Deacetylation of Lysine 56 of Histone H3 in Silent Chromatin

(2008) Bo Yang et al.   MOLECULAR BIOLOGY OF THE CELL

FACT-Mediated Exchange of Histone Variant H2AX Regulated by Phosphorylation of H2AX and ADP-Ribosylation of Spt16

(2008) Kyu Heo et al.   MOLECULAR CELL

Combination therapeutic approaches for the management of invasive aspergillosis in organ transplant recipients

(2008) Nina Singh et al.   MYCOSES

The structural basis of protein acetylation by the p300/CBP transcriptional coactivator

(2008) Xin Liu et al.   NATURE

Chemical probes for histone-modifying enzymes

(2008) Philip A Cole   Nature Chemical Biology

Molecular functions of the histone acetyltransferase chaperone complex Rtt109–Vps75

(2008) Christopher E Berndsen et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Histone chaperone specificity in Rtt109 activation

(2008) Young-Jun Park et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Fungal Rtt109 histone acetyltransferase is an unexpected structural homolog of metazoan p300/CBP

(2008) Yong Tang et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Structure of Vps75 and implications for histone chaperone function

(2008) Y. Tang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Acetylation in the globular core of histone H3 on lysine-56 promotes chromatin disassembly during transcriptional activation

(2008) Stephanie K. Williams et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Molecular basis for the autoregulation of the protein acetyl transferase Rtt109

(2008) P. Stavropoulos et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Structural Insights into Histone H3 Lysine 56 Acetylation by Rtt109

(2008) Chengqi Lin et al.   STRUCTURE

Cell Cycle– and Chaperone-Mediated Regulation of H3K56ac Incorporation in Yeast

(2008) Tommy Kaplan et al.   PLoS Genetics

Nucleosome destabilization in the epigenetic regulation of gene expression

(2007) Steven Henikoff   NATURE REVIEWS GENETICS