期刊
CRITICAL CARE MEDICINE
卷 38, 期 3, 页码 766-770出版社
LIPPINCOTT WILLIAMS & WILKINS
DOI: 10.1097/CCM.0b013e3181cd122a
关键词
sleep deprivation; residents; patient safety; medical errors; patient simulation
资金
- Canadian Patient Safety Institute
- Michael Smith Foundation for Health Research (MSFHR)
- BC Lung Association
- Canadian Institutes of Health Research
- Vancouver Coastal Health Research Institute
Objective: To evaluate the impact of prolonged continuous wakefulness on resident performance under controlled experimental conditions. Design: Experimental within-subjects comparison. Setting: High-fidelity patient simulator. Participants: Twelve residents in an Internal Medicine Program at various stages of training (range, 1-35 mos). Measurements: Performance was studied during 26 hrs of continuous wakefulness at four time points (8:00-10:00 AM, 2:00-4:00 PM, 2: 00-4: 00 AM, and 8: 00-10: 00 AM the next day) using high-fidelity patient simulation. At each session, residents managed eight simulated dysrhythmias according to advanced cardiac life support protocols (advanced cardiac life support scenarios) and then managed a simulated critically ill patient (e.g., patient with meningitis) to test more complicated clinical decision-making (complex scenario). The frequency of previously defined major medical errors (i.e., action or inaction that likely would have resulted in significant harm in a real patient) was assessed by a scorer blinded to the time of the session. For each complex scenario, a global score between 0 and 100 was also given for overall performance. The impact of wakefulness on performance was assessed by using longitudinal mixed-effects models. Results: For the complex scenarios, the mean number of errors increased from 0.92 +/- 0.90 in the first session to 1.58 +/- 0.79 in the fourth session (p=.09), and mean global score decreased from 56.8 +/- 14.6 to 49.6 +/- 12.6 (p=.02). For the advanced cardiac life support scenarios, the mean number of major errors committed in the advanced cardiac life support scenarios decreased during the study period (p=.01). However, essentially all of the improvement occurred between the first and second time points, suggesting that a substantial learning effect accounted for the findings. Conclusions: During prolonged continuous wakefulness of medical residents, clinical performance in the management of a simulated critically ill patient deteriorates. The practice of scheduling residents for extended work shifts (>24 hrs) should be reconsidered. (Crit Care Med 2010; 38: 766-770)
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