Article
Neurosciences
Ann-Katrin Ohlerth, Roelien Bastiaanse, Chiara Negwer, Nico Sollmann, Severin Schramm, Axel Schroeder, Sandro M. Krieg
Summary: In preoperative language mapping using nTMS, incorporating action naming and detailed error analysis can improve accuracy. Results show higher error rates during action naming compared to object naming in both hemispheres, indicating that lexico-semantic retrieval of verbs is more affected.
Article
Neurosciences
Ibrahim Can Yasa, Ilknur Mavis, Celal Salcini, Ipek Midi
Summary: This study aimed to demonstrate the interactive benefits of combining classical intervention strategies with new technological approaches, and to show their effectiveness in aphasia treatment. The results showed that the group in which transcranial magnetic stimulation (TMS) and speech and language therapy were applied consecutively had further improvements in speech fluency, repetition, and naming scores. The use of TMS alone was insufficient, but combining it with speech and language therapy significantly increased the therapeutic gains.
JOURNAL OF STROKE & CEREBROVASCULAR DISEASES
(2023)
Article
Clinical Neurology
Andrea Gajardo-Vidal, Diego L. Lorca-Puls, Holly Warner, Bawan Pshdary, Jennifer T. Crinion, Alexander P. Leff, Thomas M. H. Hope, Sharon Geva, Mohamed L. Seghier, David W. Green, Howard Bowman, Cathy J. Price
Summary: By studying the impact of damage to Broca's area and surrounding regions, it was found that long-term speech production outcome is mainly influenced by damage to white matter above the insula, in the vicinity of the anterior part of the arcuate fasciculus, rather than damage to Broca's area alone.
Article
Neurosciences
Ann-Katrin Ohlerth, Roelien Bastiaanse, Chiara Negwer, Nico Sollmann, Severin Schramm, Axel Schroeder, Sandro M. Krieg
Summary: Visualization of functionally significant subcortical white matter fibers is essential in neurosurgery to protect language networks. Different language tasks can impact mapping and tracking processes, with Action Naming task ROIs showing advantages in visualizing lexico-semantic tracts in the ventral stream.
FRONTIERS IN HUMAN NEUROSCIENCE
(2021)
Article
Clinical Neurology
Leonardo Bonilha, Chris Rorden, Rebecca Roth, Souvik Sen, Mark S. George, Julius Fridriksson
Summary: The study indicates that tDCS combined with speech therapy can enhance treatment effectiveness in individuals with Broca's aphasia, but does not show significant benefits for other types of aphasia.
JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY
(2023)
Article
Neurosciences
Tingni Li, Xiaoxia Zhu, Xiuqin Wu, Yulai Gong, Jeffery A. Jones, Peng Liu, Yichen Chang, Nan Yan, Xi Chen, Hanjun Liu
Summary: This study investigated the causal roles of the left and right supramarginal gyrus (SMG) in auditory feedback control of vocal production. Stimulation of both the left and right SMG led to decreased vocal compensations and reduced cortical P2 responses. No significant differences were found in the vocal and ERP responses when comparing stimulation over the left vs. right SMG, indicating a bilateral causal influence of the SMG on auditory feedback control.
Article
Oncology
Sebastian Ille, Axel Schroeder, Lucia Albers, Anna Kelm, Doris Droese, Bernhard Meyer, Sandro M. Krieg
Summary: The study proves that glioma resection in language-eloquent areas can be done without awake surgery in most cases using preoperative nrTMS mapping. Functional and radiological outcomes were comparable in both groups, but the awake group had significantly higher eloquence scores compared to the nrTMS group. The newly developed classification for language eloquence of brain tumors enables better comparison of tumor localizations and correlates with clinical outcomes.
Review
Clinical Neurology
Alexander F. Haddad, Jacob S. Young, Mitchel S. Berger, Phiroz E. Tarapore
Summary: Preoperative mapping of cortical structures can provide neurosurgeons with a roadmap of the brain, allowing for improved operative planning, patient risk stratification, and personalized counseling. Navigated transcranial magnetic stimulation (nTMS) is a highly accurate and non-invasive modality that can differentiate between eloquent and non-eloquent cortical regions, with motor mapping being the best validated application. Language mapping is also common, but not as concordant with intraoperative mapping as motor mapping. Additionally, nTMS has been used for localizing cortical regions involved in various functions beyond motor and language processing.
FRONTIERS IN NEUROLOGY
(2021)
Article
Audiology & Speech-Language Pathology
Brendan Tomoschuk, Victor S. Ferreira, Tamar H. Gollan
Summary: In the picture-word interference task, semantically related distractors can slow down production, while translation-equivalent distractors may speed it up. Research suggests that bilinguals do not restrict their selection to one language, and during language switching, there can be a reversal of language dominance with inhibition of the dominant language and competition between languages.
LANGUAGE COGNITION AND NEUROSCIENCE
(2021)
Article
Integrative & Complementary Medicine
Samwel Sylvester Msigwa, Yan Li, Xiang-lin Cheng, Fen Cao
Summary: This study retrospectively analyzed the therapeutic consequences of combining electroacupuncture and transcranial direct current stimulation (tDCS) with speech and language therapy (SLT) in subacute post-stroke aphasia (PSA) patients. The results showed significant improvements in spontaneous conversation and naming ability in the acupuncture group, as well as improvement in word retrieval. Future clinical trials are needed to further validate the effectiveness of this treatment approach.
JOURNAL OF INTEGRATIVE MEDICINE-JIM
(2022)
Article
Psychology, Mathematical
Agnieszka Ewa Krautz, Emmanuel Keuleers
Summary: This study aimed to address the limitations of existing picture data sets in psychological and linguistic research by creating a new database of normed color images through a megastudy approach. Linguistic norms such as speech onset times, name agreement, accuracy, familiarity, visual complexity, valence, and arousal were established using 1620 color photographs named and rated by German speakers. The data were used to create the LinguaPix database, the largest available research tool of its kind.
BEHAVIOR RESEARCH METHODS
(2022)
Article
Neurosciences
Chen Feng, Markus F. Damian, Qingqing Qu
Summary: Recent research suggests that access to semantic and phonological information during spoken language production occurs in parallel rather than in sequential stages, with both types of information accessed at a similar latency and within a similar time window.
JOURNAL OF COGNITIVE NEUROSCIENCE
(2021)
Article
Clinical Neurology
Shalini Narayana, Savannah K. Gibbs, Stephen P. Fulton, Amy Lee McGregor, Basanagoud Mudigoudar, Sarah E. Weatherspoon, Frederick A. Boop, James W. Wheless
Summary: This study showed that transcranial magnetic stimulation (TMS) can be a safe, reliable, and effective tool to map eloquent cortices in young children with neurological diseases. Successful localization of motor, speech, and language cortices improved the understanding of the risk-benefit ratio prior to surgery and facilitated surgical planning aimed at preserving motor, speech, and language functions. Post-operatively, motor and language functions were preserved or improved in most children who underwent surgery for lesions near eloquent cortices.
FRONTIERS IN NEUROLOGY
(2021)
Article
Behavioral Sciences
Francesca Vitale, Ilaria Monti, Ivan Padron, Alessio Avenanti, Manuel de Vega
Summary: Applying negation in action contexts reduces motor system activation. The right inferior frontal gyrus (rIFG), a key area of the inhibitory control system, was found to contribute to the processing of negated action-sentences in the primary motor cortex (M1). Modulating rIFG suppressed the inhibitory effect of negation, resulting in equal motor excitability for negative and affirmative action sentences.
Article
Medicine, General & Internal
Seung Yeon Jeon, Jung Ho Choi, Sun Seong Kang, Yong-Hwi An, Hyun Joon Shim
Summary: Personalized neuromodulation, where treatment modalities are chosen based on the patient's responses in a pilot trial, is an advantageous strategy for treating tinnitus. The study found that the improvement in Tinnitus Handicap Inventory (THI) score after 10 sessions of each neuromodulation was significantly greater in the personalized group compared to the randomized group.
JOURNAL OF CLINICAL MEDICINE
(2023)
Article
Clinical Neurology
Zubeyir Bayraktaroglu, Tuba Akturk, Gorsev Yener, Tom A. de Graaf, Lutfu Hanoglu, Ebru Yildirim, Duygu Hunerli Gunduz, Ilayda Kiyi, Alexander T. Sack, Claudio Babiloni, Bahar Guntekin
Summary: Parkinson's disease patients with mild cognitive impairment exhibit abnormal neurophysiological oscillatory mechanisms, primarily driven by delta frequencies, during cognitive tasks.
CLINICAL EEG AND NEUROSCIENCE
(2023)
Editorial Material
Psychiatry
Chih-Sung Liang, Po-Han Chou, Shao-Cheng Wang, Alexander T. Sack, Kuan-Pin Su
FRONTIERS IN PSYCHIATRY
(2023)
Article
Psychology, Clinical
Mathilde Kennis, Felix Duecker, Els Elaut, Guy T'Sjoen, Tom Loeys, Alexander T. Sack, Marieke Dewitte
Summary: Multiple surveys have shown that transgender individuals have lower sexual well-being compared to cisgender individuals. However, previous studies have limitations in terms of ecological validity and memory bias. In this diary study, transgender and cisgender individuals reported on their sexual behavior, sexual esteem, and body image for three weeks. The findings suggest that intimacy predicts sexual esteem in transgender individuals, while sexual openness predicts sexual esteem and body image. Transgender individuals scored lower on daily sexual esteem and body image than cisgender individuals, but there were no differences in daily sexual behavior. Clinicians should consider sexuality more broadly and address sexual esteem when discussing sexuality with transgender patients.
JOURNAL OF SEX RESEARCH
(2023)
Article
Neurosciences
Alessandra Pizzuti, Laurentius (Renzo) Huber, Omer Faruk Gulban, Amaia Benitez-Andonegui, Judith Peters, Rainer Goebel
Summary: Researchers have used ultra-high field functional magnetic resonance imaging (fMRI) to investigate the microscopic features of direction-selective neurons in the motion sensitive area of the human brain. They have found that blood volume-sensitive fMRI can be used to detect the columnar organization of this brain area at a larger scale. This study provides new insights and possibilities for understanding the mesoscopic functional organization of the human brain.
Article
Neurosciences
Fatemeh Tabassi Mofrad, Niels O. Schiller
Summary: Using multiband echo planar imaging (EPI), the study explored the connectivity profile of the middle inferior parietal cortex (IPC) and found that it exhibited functional associations inconsistent with traditional brain area categorization. It showed negative functional connectivity with both resting-state related cortex and brain areas related to general cognitive functions.
Article
Neurosciences
Ruixue Wu, Niels O. Schiller
Summary: This study found evidence for the gender congruency effect in native Spanish speakers, demonstrating that grammatical gender is used to competitively select determiners in noun phrases. These findings are important for understanding the gender congruency effect in Romance languages.
Article
Psychology, Clinical
Priya T. Gajadien, Tjardo S. Postma, Iris van Oostrom, Karel W. F. Scheepstra, Hanneke van Dijk, Alexander T. Sack, Odile A. van den Heuvel, Martijn Arns
Summary: Sleep problems can predict the response of treatment resistant OCD patients to repetitive transcranial magnetic stimulation (rTMS). The PSQI items of subjective sleep quality, sleep latency, and daytime dysfunction, as well as the HSDQ-insomnia scale, were found to predict treatment response.
INTERNATIONAL JOURNAL OF CLINICAL AND HEALTH PSYCHOLOGY
(2023)
Article
Psychology, Clinical
Georgios Mikellides, Panayiota Michael, Lilia Psalta, Artemis Stefani, Teresa Schuhmann, Alexander T. Sack
Summary: The study investigated the long-term effects of accelerated intermittent theta burst stimulation (aiTBS) in smoking cessation, showing that the positive effects on nicotine dependence and tobacco craving lasted for at least one month after treatment, but dissipated after six months. No significant differences were found between the three groups.
INTERNATIONAL JOURNAL OF CLINICAL AND HEALTH PSYCHOLOGY
(2023)
Article
Psychiatry
Theodoros Koutsomitros, Sandra A. Schwarz, Kenneth T. van der Zee, Teresa Schuhmann, Alexander T. Sack
Summary: This study assessed the feasibility and clinical effectiveness of home-administered transcranial direct current stimulation (tDCS) with asynchronous remote supervision in the treatment of depression. The results showed that the tDCS group had a significantly greater reduction in depression symptoms after 3 weeks of treatment compared to the treatment as usual (TAU) group.
FRONTIERS IN PSYCHIATRY
(2023)
Review
Radiology, Nuclear Medicine & Medical Imaging
Dimo Ivanov, Federico De Martino, Elia Formisano, Francisco J. Fritz, Rainer Goebel, Laurentius Huber, Sriranga Kashyap, Valentin G. Kemper, Denizhan Kurban, Alard Roebroeck, Shubharthi Sengupta, Bettina Sorger, Desmond H. Y. Tse, Kamil Uludag, Christopher J. Wiggins, Benedikt A. Poser
Summary: This article reviews the 9.4 T work done in Maastricht, including functional and anatomical imaging experiments. By utilizing specific techniques and optimized coils, the researchers were able to obtain high-quality imaging results and highlight the technical challenges and practical issues associated with ultra-high field MRI.
MAGNETIC RESONANCE MATERIALS IN PHYSICS BIOLOGY AND MEDICINE
(2023)
Review
Radiology, Nuclear Medicine & Medical Imaging
Steve Bates, Serge O. Dumoulin, Paul J. M. Folkers, Elia Formisano, Rainer Goebel, Aidin Haghnejad, Rick C. Helmich, Dennis Klomp, Anja G. van der Kolk, Yi Li, Aart Nederveen, David G. Norris, Natalia Petridou, Stefan Roell, Tom W. J. Scheenen, Menno M. Schoonheim, Ingmar Voogt, Andrew Webb
Summary: We propose a vision for a 14 Tesla MR system, which includes a novel whole-body magnet design using high temperature superconductor, a console and associated electronic equipment, an optimized radiofrequency coil setup for proton measurement in the brain, and a high-performance gradient set. This system has significant applications in neuroscience and medical research, allowing for fine-grained observation of neural activity and structural abnormalities.
MAGNETIC RESONANCE MATERIALS IN PHYSICS BIOLOGY AND MEDICINE
(2023)
Article
Neurosciences
Lauren Zwienenberg, Hanneke van Dijk, Stefanie Enriquez-Geppert, Nikita van der Vinne, Richard Gevirtz, Evian Gordon, Alexander T. Sack, Martijn Arns
Summary: Currently, major depressive disorder (MDD) treatment plans are based on trial-and-error, and remission rates remain low. A strategy to replace trial-and-error and increase remission rates could be treatment stratification using the heartbeat-evoked potential (HEP) as a biomarker. The study found that using HEP as a stratification biomarker can enhance treatment outcome prediction for venlafaxine and rTMS.
NEUROPSYCHOBIOLOGY
(2023)
Article
Clinical Neurology
Hannah Meijs, Helena Voetterl, Alexander T. Sack, Hanneke van Dijk, Bieke De Wilde, Jan Van Hecke, Peter Niemegeers, Evian Gordon, Jurjen J. Luykx, Martijn Arns
Summary: This study used a polygenic score (PGS) and electroencephalography (EEG) data analysis to identify potential predictors for treatment outcomes in major depressive disorder (MDD). The results suggest the existence of a stable EEG network related to antidepressant-response that has potential as a predictor for MDD treatment, particularly in the case of venlafaxine.
EUROPEAN NEUROPSYCHOPHARMACOLOGY
(2024)
Article
Neurosciences
Aline M. Dantas, Alexander T. Sack, Elisabeth Bruggen, Peiran Jiao, Teresa Schuhmann
Summary: This study investigated the functional relevance of frontal theta-band activity in decision-making using transcranial alternating current stimulation (tACS) over right or left dorsolateral prefrontal cortex (DLPFC). The results showed that risk-taking behavior increased after left DLPFC stimulation and decreased after right DLPFC stimulation. Furthermore, stimulation intensity had an effect on behavioral responses.
Review
Behavioral Sciences
Ting Wang, Tom de Graaf, Joshua Williams, Zhihao Wang, Teresa Schuhmann, Felix Duecker, Alexander T. Sack
Summary: Spatial attention control involves specialized functions in both hemispheres of the brain, leading to hemispheric asymmetries. Neuropsychological models explain this lateralization mainly based on patient studies of hemineglect. Our meta-analysis assessed inhibitory TMS effects on PPC during visual detection tasks across ten studies (1994-2022). These results call for a re-evaluation of current theoretical models of attention and their application to novel brain stimulation-based therapeutic interventions.
NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS
(2023)
Article
Behavioral Sciences
Andrea Gajardo-Vidal, Maxime Montembeault, Diego L. Lorca-Puls, Abigail E. Licata, Rian Bogley, Sabrina Erlhoff, Buddhika Ratnasiri, Zoe Ezzes, Giovanni Battistella, Elena Tsoy, Christa Watson Pereira, Jessica Deleon, Boon Lead Tee, Maya L. Henry, Zachary A. Miller, Katherine P. Rankin, Maria Luisa Mandelli, Katherine L. Possin, Maria Luisa Gorno-Tempini
Summary: This study investigates the potential differences in processing speed and neural correlates among the three variants of Primary Progressive Aphasia (PPA). The findings reveal that non-verbal cognitive abilities, such as processing speed, are significantly impacted in nfvPPA and lvPPA patients compared to healthy controls and svPPA patients. Neuroimaging results confirm the importance of fronto-parietal regions associated with processing speed and executive control.
Article
Behavioral Sciences
Holger Wiese, Tsvetomila Popova, Maya Schipper, Deni Zakriev, Mike Burton, Andrew W. Young
Summary: Previous experiments have shown that brief exposure to unfamiliar individuals leads to the formation of new facial representations, which undergo changes and consolidation within the first day after learning.
Article
Behavioral Sciences
Astrid Prochnow, Xianzhen Zhou, Foroogh Ghorbani, Paul Wendiggensen, Veit Roessner, Bernhard Hommel, Christian Beste
Summary: Individuals organize events in their environment by partitioning them into discrete units. This study reveals that the neural activity in the brain plays a critical role in this process, reflecting the key elements of event segmentation.
Article
Behavioral Sciences
Zhenzhen Huo, Zhiyi Chen, Rong Zhang, Junye Xu, Tingyong Feng
Summary: Procrastination has adverse effects on personal growth and social development. Reward sensitivity is positively correlated with procrastination. This study used VBM and RSFC analyses to investigate the neural substrates underlying the association between reward sensitivity and procrastination. The results showed that the functional connectivity of the right parahippocampal gyrus-precuneus mediated the relationship between reward sensitivity and procrastination.
Article
Behavioral Sciences
Stefano Lasaponara, Gabriele Scozia, Silvana Lozito, Mario Pinto, David Conversi, Marco Costanzi, Tim Vriens, Massimo Silvetti, Fabrizio Doricchi
Summary: Cholinergic (Ach), Noradrenergic (NE), and Dopaminergic (DA) pathways are crucial in regulating spatial attention and determining inter-individual differences in temperamental traits. This study found that temperamental traits predict individual differences in the ability to orient spatial attention based on the probabilistic association between cues and targets. These findings highlight the importance of considering temperamental and personality traits in social and professional environments where attention control is essential.
Article
Behavioral Sciences
Darren J. Yeo, Courtney Pollack, Benjamin N. Conrad, Gavin R. Price
Summary: The processing of numerals as visual objects is supported by an Inferior Temporal Numeral Area (ITNA) in the bilateral inferior temporal gyri (ITG). Extant findings suggest some degree of hemispheric asymmetry in how the bilateral ITNAs process numerals. The study found that digit sensitivity did not differ between ITNAs, and digit sensitivity in both left and right ITNAs was associated with calculation skills. The study also revealed a right lateralization in engagement in alphanumeric categorization, and that the right ITNA showed greater discriminability between digits and letters.
Review
Behavioral Sciences
Beste Gulsuna, Abuzer Gungor, Alp O. Borcer, Ugur Ture
Summary: The fiber dissection technique has been used to study the internal structures of the brain, with less focus on white matter. The sagittal stratum, a white matter structure, has not received enough attention and has been a subject of controversy. Recent studies suggest potential functions of the sagittal stratum, emphasizing the importance of understanding this structure accurately.
Article
Behavioral Sciences
Nora Geiser, Brigitte Charlotte Kaufmann, Samuel Elia Johannes Knobel, Dario Cazzoli, Tobias Nef, Thomas Nyffeler
Summary: This study compared the effects of auditory and visual motion stimulation on spatial neglect and found that both interventions were equally effective in improving neglect. Multimodal motion stimulation also improved neglect, but did not show greater improvement than unimodal auditory or visual motion stimulation alone.
Article
Behavioral Sciences
Anna E. Hughes, Anna Nowakowska, Alasdair D. F. Clarke
Summary: This study examines the relationship between search slopes and search efficiency in visual search tasks, introduces the Target Contrast Signal (TCS) Theory, and extends it to a Bayesian multi-level framework. The findings demonstrate that TCS can predict data well, but distinguishing between contrast combination models proves to be difficult.
