Article
Ophthalmology
Alfonso Vasquez-Perez, Nizar Din, Maria Phylactou, Jaime Kriman Nunez, Bruce Allan
Summary: The technique of mini-Descemet stripping endothelial keratoplasty presents a successful solution for paracentral macroperforations, preserving good vision and avoiding challenges of traditional keratoplasty. The laboratory test confirms that this technique can seal macroperforations effectively, restoring eye globe integrity and achieving long-term stability.
Article
Ophthalmology
Artemis Matsou, Rathin Pujari, Hammad Sarwar, Mrinal Rana, James Myerscough, Susan M. Thomson, Girinath Nandakumar, Jufen Zhang, Madhavan S. Rajan
Summary: The study compared the outcomes of MT-DSAEK and DMEK surgeries for Fuchs dystrophy. Results showed that DMEK surgery led to significantly better BSCVA at 1, 3, 6, and 12 months postoperatively, with similar complication rates and vision-related QoL scores between the two groups.
Article
Ophthalmology
Andreas Viberg, Branka Samolov, Berit Bystroem
Summary: The study compares the outcomes of different posterior lamellar corneal transplant procedures for Fuchs endothelial corneal dystrophy, taking into consideration preoperative patient characteristics. The results show that all three surgical methods improved visual acuity in the majority of patients, but DMEK and phacoemulsification plus DSAEK achieved higher levels of visual acuity after 2 years, and phacoemulsification plus DSAEK had a superior graft survival rate. The choice of surgical method should be personalized, considering not only the corneal condition but also each patient's complete medical status and postoperative medical care.
Article
Ophthalmology
Rathin Pujari, Artemis Matsou, Jane Kean, Jufen Zhang, Madhavan S. Rajan
Summary: The study found no significant difference in BSCVA and endothelial cell density between DMEK and MT-DSAEK at 24 months, with a reduced difference compared to 1-year results. Both techniques showed similar outcomes for complication rates, endothelial cell loss, and patient-reported vQoL scores.
Article
Ophthalmology
Jorge Peraza-Nieves, Jose-Maria Sanchez-Gonzalez, Carlos Rocha-de-Lossada, Rahul Rachwani-Anil, Miriam Sanchez-Valera, Davide Borroni, Josep Torras-Sanvicens
Summary: The study compared corneal densitometry values between DMEK and DSAEK surgeries, finding no differences by layers or at central-paracentral concentric zones, but statistically significant differences in the peripheral zones.
INTERNATIONAL OPHTHALMOLOGY
(2021)
Article
Medicine, General & Internal
Josep Torras-Sanvicens, Irene Blanco-Dominguez, Jose-Maria Sanchez-Gonzalez, Rahul Rachwani-Anil, Juan-Felipe Spencer, Noelia Sabater-Cruz, Jorge Peraza-Nieves, Carlos Rocha-de-Lossada
Summary: UT-DSAEK and DMEK showed similar objective and subjective visual quality results, with DMEK demonstrating faster recovery, increased endothelial cell density, lower pachymetry, and more anatomical posterior keratometry compared to UT-DSAEK in this paired-eye study.
JOURNAL OF CLINICAL MEDICINE
(2021)
Article
Ophthalmology
Marianne O. Price, Francis W. Price
Summary: The purpose of this study was to evaluate the 15-year outcomes of Descemet stripping endothelial keratoplasty (DSEK). The results showed that DSEK provided excellent long-term visual rehabilitation and graft survival in this early cohort.
Article
Ophthalmology
Michael Mimouni, Nir Sorkin, Jacqueline Slomovic, Eli Kisilevsky, Zale Mednick, Eyal Cohen, Tanya Trinh, Gisella Santaella, Clara C. Chan, David S. Rootman, Allan R. Slomovic
Summary: The study compared outcomes of DMEK and DSAEK in complex eyes undergoing vitrectomy. DMEK had a higher proportion of Fuchs' patients and higher rates of serious adverse events postoperatively compared to DSAEK.
CURRENT EYE RESEARCH
(2021)
Article
Ophthalmology
Pranita Sahay, Rajesh Fogla, Namrata Sharma
Summary: This study investigated the preferred surgical technique of Descemet membrane endothelial keratoplasty (DMEK) among corneal surgeons in India, as well as barriers faced by non-DMEK surgeons in performing this procedure. The results showed that DMEK was the most commonly used technique, but lack of training was the main reason for not performing DMEK among non-DMEK surgeons. The study also found that most DMEK surgeons found unrolling the graft in the anterior chamber to be the most difficult step, and they were more comfortable with using DSEK or DSAEK techniques.
INDIAN JOURNAL OF OPHTHALMOLOGY
(2022)
Article
Ophthalmology
Vikas Mittal, Nancy Sehdev, Ruchi Mittal
Summary: This study aimed to investigate the application of Descemet membrane endothelial keratoplasty (DMEK) in patients with congenital hereditary endothelial dystrophy (CHED). The results showed that DMEK surgery significantly improved visual acuity and corneal thickness. However, some patients may experience graft rejection after surgery.
Article
Ophthalmology
Chandradevi Shanmugam, Rinky Agarwal, Mohamed Ibrahime Asif, Rahul Kumar Bafna, Prafulla Kumar Maharana, Tushar Agarwal, Rajesh Sinha, Jeewan Singh Titiyal, Namrata Sharma
Summary: The purpose of this study was to compare the outcomes of pre-Descemet endothelial keratoplasty (PDEK) and Descemet membrane endothelial keratoplasty (DMEK) in cases of endothelial decompensation. The patients were followed up for 6 months after surgery and it was found that both surgeries had comparable visual and graft survival outcomes.
Review
Ophthalmology
Masomeh Mohebbi, Mohammad Mehrpour, Amin Dehghani Sanij, Nader Mohammadi, Masoud Mirghorbani
Summary: Endothelial keratoplasty (EK) is increasingly being considered as the first intervention in treating corneal endothelial dysfunction in children. Descemet's stripping automated endothelial keratoplasty (DSAEK) is the most commonly performed procedure for pediatric patients. Despite some technical challenges, EK procedures show acceptable visual and anatomical outcomes in pediatric cases, with graft dislocation being the most common complication.
GRAEFES ARCHIVE FOR CLINICAL AND EXPERIMENTAL OPHTHALMOLOGY
(2022)
Article
Medicine, General & Internal
Antonio Ballesteros-Sanchez, Jorge Peraza-Nieves, Anna Casablanca-Pinera, Marina Rodriguez-Calvo-De-Mora, Saray Catalan-Coronado, Josep Torras-Sanvicens, Davide Borroni, Jose-Maria Sanchez-Gonzalez, Carlos Rocha-De-Lossada
Summary: This study compared corneal densitometry patterns between DMEK and DSAEK procedures. The results showed that DMEK had significantly lower corneal density and CD values compared to DSAEK. Additionally, DMEK showed better BCDVA, CCT, and GT values.
JOURNAL OF CLINICAL MEDICINE
(2023)
Article
Ophthalmology
Julia Pickel, Winston D. Chamberlain, Charles C. Lin, Ariana Austin, Jameson Clover, Thomas M. Lietman, Jennifer Rose-Nussbaumer
Summary: Bilateral endothelial keratoplasty showed higher vision-related quality of life after 12 months compared to unilateral, while baseline densitometry, as an objective measure of corneal haze, may play a key role in predicting vision-related quality of life.
Article
Medicine, General & Internal
Carlos Rocha-de-Lossada, Jose-Maria Sanchez-Gonzalez, Davide Borroni, Victor Llorens-Belles, Rahul Rachwani-Anil, Josep Torras-Sanvicens, Vito Romano, Jorge Peraza-Nieves
Summary: In patients with Fuchs endothelial corneal dystrophy (FECD) undergoing Descemet membrane endothelial keratoplasty (DMEK), chord mu length decreased significantly within the first three months postoperatively and remained stable after 12 months, while chord alpha length remained stable throughout the 12-month follow-up period.
JOURNAL OF CLINICAL MEDICINE
(2021)
Article
Ophthalmology
Anand Pasari, Marianne O. Price, Matthew T. Feng, Francis W. Price
Editorial Material
Ophthalmology
Francis W. Price, Marianne O. Price
Letter
Ophthalmology
Anand Pasari, Marianne O. Price, Matthew T. Feng, Francis W. Price
Article
Ophthalmology
Kavitha Subramaniam, Marianne O. Price, Matthew T. Feng, Francis W. Price
Article
Ophthalmology
Alejandro Saint-Jean, Mark Soper, Kyle Den Beste, Shawn Iverson, Marianne O. Price, Francis W. Price
Article
Ophthalmology
Enrique S. Malbran, Francis W. Price, Joaquin E. Arganaraz Olivero, Enrique Malbran Jr, Jorge Malbran, Marcos Malbran, Leandro N. Rogel, Marianne O. Price, Carlos H. Gordillo
Article
Ophthalmology
Marianne O. Price, Denisse Pinkus, Francis W. Price
Article
Biochemistry & Molecular Biology
Taiga Miyajima, Geetha Melangath, Shan Zhu, Neha Deshpande, Shivakumar Vasanth, Bodhisattwa Mondal, Varun Kumar, Yuming Chen, Marianne O. Price, Francis W. Price, Eleanor G. Rogan, Muhammad Zahid, Ula Jurkunas
FREE RADICAL BIOLOGY AND MEDICINE
(2020)
Article
Ophthalmology
Marianne O. Price, Matthew T. Feng, Francis W. Price
Summary: The study aimed to assess whether prophylactic use of netarsudil 0.02% ophthalmic solution reduces the risk of intraocular pressure elevation associated with prolonged use of topical corticosteroids. The results showed that there was no statistically significant reduction in the risk of steroid-induced IOP elevation after corneal transplantation relative to placebo in the netarsudil group.
AMERICAN JOURNAL OF OPHTHALMOLOGY
(2021)
Review
Ophthalmology
Marianne O. Price, Jodhbir S. Mehta, Ula Jurkunas, Francis W. Price
Summary: The cornea protects and focuses incoming light for the eye. Precise control of corneal hydration by endothelial cells is vital for transparency and visual health. Advances in corneal transplantation offer new options for treating dysfunction, while research into alternative treatments continues.
PROGRESS IN RETINAL AND EYE RESEARCH
(2021)
Article
Ophthalmology
Marianne O. Price, Matthew T. Feng, Francis W. Jr Jr Price
Summary: Endothelial keratoplasty has revolutionized the treatment of corneal endothelial dysfunction, providing rapid visual rehabilitation and high standards of safety and efficacy. Advances in techniques have improved visual outcomes and facilitated donor tissue preparation, but a shortage of human donor corneas remains a challenge, driving the search for alternatives to traditional keratoplasty. More work is needed to expand the donor supply, address adoption barriers, optimize graft survival, and improve refractive predictability.
Article
Ophthalmology
Juan G. Arbelaez, Maria C. Arbelaez
Summary: The study demonstrates that implanting asymmetric progressive thickness intrastromal corneal ring segments can improve visual acuity and corneal flattening in patients with asymmetric duck phenotype keratoconus, while reducing refractive error and corneal aberrations.
EUROPEAN JOURNAL OF OPHTHALMOLOGY
(2021)
Article
Ophthalmology
Marianne O. Price, Francis W. Price
Summary: The off-label use of netarsudil 0.02% showed significant reduction in central corneal thickness and improvement in scotopic corrected distance visual acuity in patients with Fuchs dystrophy. Further studies are needed to fully assess patient satisfaction and compare netarsudil with other treatment options.
AMERICAN JOURNAL OF OPHTHALMOLOGY
(2021)
Article
Ophthalmology
Marianne O. Price, Francis W. Price
Summary: The purpose of this study was to evaluate the 15-year outcomes of Descemet stripping endothelial keratoplasty (DSEK). The results showed that DSEK provided excellent long-term visual rehabilitation and graft survival in this early cohort.
Article
Ophthalmology
Jad F. Assaf, Dan Z. Reinstein, Cyril Zakka, Juan G. Arbelaez, Peter Boufadel, Mathieu Choufani, Timothy Archer, Perla Ibrahim, Shady T. Awwad
Summary: In this study, a deep learning neural network was developed and validated to automatically measure the vault of implantable collamer lens (ICL) using anterior segment optical coherence tomography (AS-OCT). By using transfer learning, the model achieved high accuracy in estimating the ICL vault from AS-OCT scans with a MAPE of 3.42%, an MAE of 15.82µm, and a Pearson correlation coefficient r of +0.98.
AMERICAN JOURNAL OF OPHTHALMOLOGY
(2023)