Article
Chemistry, Organic
Seung Hyeon Kim, Yerim Yeon, Areum Lee, Vincent M. Lynch, Qing He, Jonathan L. Sessler, Sung Kuk Kim
Summary: A calix[4]arene compound 1 functionalized with amidoindole groups on the upper rim and with propyl groups on the lower rim was synthesized. It was found that compound 1 can bind the lithium cation and the chloride anion concurrently with enhanced affinity. Additionally, compound 1 can selectively extract and solubilize LiCl and LiBr into chloroform.
ORGANIC CHEMISTRY FRONTIERS
(2022)
Article
Chemistry, Inorganic & Nuclear
Mamina Bhol, Guilhem Claude, Maximilian Roca Jungfer, Ulrich Abram, Malaichamy Sathiyendiran
Summary: In this study, calix[4]arene-analogous technetium supramolecules and rhenium-based macrocycles were successfully assembled by using specific ligands and starting materials. The structures of these molecules were characterized in detail.
INORGANIC CHEMISTRY
(2022)
Article
Chemistry, Inorganic & Nuclear
Lucinda R. B. Wilson, Marco Coletta, Mukesh K. Singh, Simon J. Teat, Adam Brookfield, Muralidharan Shanmugam, Eric J. L. McInnes, Stergios Piligkos, Scott J. Dalgarno, Euan K. Brechin
Summary: The reaction of 2,2'-bis-p-Bu-t-calix[4]arene (H8L) with Cu(NO3) (2)center dot 3H(2)O and N-methyldiethanolamine (MedeaH(2)) in a basic dmf/MeOH mixture results in the formation of [Cu-II (16)(L)(2)(Me-dea)(4)(mu(4)-NO3)(2)(mu-OH)(4)(dmf)(3.5)(MeOH)(0.5)(H2O)(2)] (H6L)center dot 16dmf center dot 4H(2)O (4). The metallic skeleton of the compound consists of a tetracapped square prism, [Cu-12], with Cu-II ions housed in the calix[4]arene polyphenolic pockets. Magnetic measurements show antiferromagnetic exchange interactions and a ground state of S = 1, while EPR indicates a large zero-field splitting.
DALTON TRANSACTIONS
(2023)
Review
Spectroscopy
Priyanka Kashyap, Payal Sharma, Ritu Gohil, Dushyantsingh Rajpurohit, Divya Mishra, Pranav S. Shrivastav
Summary: In the past two decades, significant progress has been made in the design and development of synthetic receptors for molecular recognition, finding applications in various scientific fields. This review focuses on the advancement of pi-conjugated fluorogenic and chromogenic groups appended to calix[4]arene motifs for the detection and quantitation of Cu2+ ion. The comprehensive account of extended calix[4]arene systems with different linkers highlights their unique design and binding characteristics for the recognition and sensing of Cu2+ ions.
SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY
(2023)
Article
Chemistry, Multidisciplinary
Niklas Noll, Frank Wuerthner
Summary: The cyclic dinuclear ruthenium complex with oligo(ethylene glycol)-functionalized axial calix[4]arene ligands showed enhanced catalytic activity in water oxidation compared to the mononuclear reference compound. The kinetic studies revealed a unimolecular water nucleophilic attack mechanism for this novel dinuclear water oxidation catalyst, demonstrating its potential for artificial photosynthesis. The photocatalytic performance of this complex was reported to be the highest among Ru(bda) complexes, indicating its promising application in the field of water oxidation research.
CHEMISTRY-A EUROPEAN JOURNAL
(2021)
Article
Chemistry, Multidisciplinary
Xu Ying, Zhenhua Zhu, Xiao-Lei Li, Jinkui Tang
Summary: We report two pairs of enantiomers of Co(II)and Zn(II)-based metallacycles constructed by coordination-driven self-assembly between homochiral 1,1 '-bi-2-naphthol-derived ligands featuring two kinds of coordination pockets and transition metal ions. Remarkably, they exhibit calix[4]arene-like topological structures and fascinating chiral cavities, having potential in enantioselective recognition.
CRYSTAL GROWTH & DESIGN
(2023)
Article
Biochemistry & Molecular Biology
Anton A. Muravev, Alexandra D. Voloshina, Anastasia S. Sapunova, Farida B. Gabdrakhmanova, Oksana A. Lenina, Konstantin A. Petrov, Sergey Shityakov, Ekaterina V. Skorb, Svetlana E. Solovieva, Igor S. Antipin
Summary: In this study, a series of calixarenes derivatized with 3-phenyl-1H-pyrazole units were synthesized and characterized. These compounds showed specific cytotoxicity for M-HeLa cells with low mutagenicity and haemotoxicity. Compound 7b and 7c induced apoptosis in M-HeLa cells through the mitochondrial pathway and arrested the cell cycle at G0/G1 phase. The overexpression of DNA damage markers in pyrazole-treated M-HeLa cells suggested that calixarene pyrazoles target DNA, which was supported by the interactions between calixarenes and ctDNA at the air-water interface.
BIOORGANIC CHEMISTRY
(2023)
Article
Biochemistry & Molecular Biology
Vladimir Burilov, Egor Makarov, Diana Mironova, Elza Sultanova, Islamiya Bilyukova, Kevser Akyol, Vladimir Evtugyn, Daut Islamov, Konstantin Usachev, Timur Mukhametzyanov, Svetlana Solovieva, Igor Antipin
Summary: This paper presents the synthesis of new water-soluble calixarene triazoles and investigates their aggregation behavior, as well as their binding and compaction abilities towards DNA. The results suggest that the tetradecyl-substituted calix[4]arene exhibits the best performance in terms of DNA binding and compaction.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2022)
Article
Chemistry, Multidisciplinary
Zhenchuang Xu, Nie Fang, Yanchuan Zhao
Summary: Regulation of recognition events evolving in time and space is essential for living organisms, with organisms developing distinct and orthogonal mechanisms to achieve selective recognition. While merging multiple selection mechanisms into a single artificial host can lead to a more adaptable recognition system with unparalleled selectivity, successful implementation of this strategy is rare. This strategy paves a new avenue for creating more robust hosts that can effectively discriminate diverse guests in complex biological environments where many recognition events occur concurrently.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
(2021)
Article
Chemistry, Multidisciplinary
Masayuki Morie, Ryo Sekiya, Takeharu Haino
Summary: In this study, a triple-stranded metallohelicate was formed by self-assembly of 5,17-difunctionalized calix[4]arenes and metal cations, showing good encapsulation properties and selectivity. CD spectroscopy confirmed the preference of the metallohelicate for guest molecules. NMR, UV-vis experiments, and molecular mechanics calculations revealed the interaction mechanism between the metallohelicate and guest molecules.
CHEMISTRY-AN ASIAN JOURNAL
(2021)
Article
Chemistry, Organic
Zuquan Wang, Yunjian Li, Jing Shi, Xiaoqiang Sun, Tangxin Xiao, Ke Yang, Zheng-Yi Li
Summary: Two novel fluorescent probes, L1 and L2, have been prepared by incorporating salicylaldehyde-derived Schiff base groups onto the upper rim of calix[4]arene. Among these probes, L2 shows the highest effectiveness in recognizing Al3+, with a highly selective fluorescence response at 478 nm emission wavelength and 88 nm Stokes shift.
EUROPEAN JOURNAL OF ORGANIC CHEMISTRY
(2023)
Review
Biochemistry & Molecular Biology
Fazel Nasuhi Pur
Summary: The calix[4]arene-based active pharmaceutical ingredients show significant anticancer and anti-infective activities, possibly due to their multivalency, facial, conical structures, and synergistic effect of their four replicated units.
MOLECULAR DIVERSITY
(2021)
Article
Chemistry, Multidisciplinary
Saber Mirzaei, Sergey Lindeman, Denan Wang, M. Saeed Mirzaei, Qadir K. Timerghazin
Summary: The discovery of a novel metastable polymorph of a calix[4]arene molecule undergoing distinct transformations, including a reversible thermal-induced rotation and irreversible dissolvation/recrystallization, demonstrates the unique structural changes and packing arrangements that can be achieved.
Article
Nanoscience & Nanotechnology
Rui Ha, Fuzhu Liu, Jie Li, Meng He, Jianhui Lan, Bowei Wang, Jun Sun, Xue Liu, Xiangdong Ding, Weiqun Shi
Summary: In this study, three calix[4]arene-decorated crystalline COFs were designed and utilized for lithium adsorption and isotope separation. The COFs showed outstanding lithium adsorption capacity and excellent lithium isotope separation performance, with a separation factor comparable to the most successful adsorbent reported in the literature. This work demonstrates the promising potential of calixarene COFs as adsorbents for lithium isotope separation.
ACS APPLIED MATERIALS & INTERFACES
(2023)
Article
Chemistry, Organic
Dirk Schlueter, Kai R. Korsching, Vladimir A. Azov
Summary: This approach involves modifying the lower rim of calix[4]arene-based molecular tweezes by attaching monopyrrolo-tetrathiafulvalene (MPTTF) arms to the upper rim. The synthesis process includes creating calixarene-MPTTF conjugates with free hydroxyl groups on the lower rim using the Ullmann reaction, followed by substitution of the hydroxyl groups with propargyl groups for further modification via the click reaction. The resulting calixarene-TTF derivatives exhibit reversible redox processes and binding affinity for electron-deficient molecular guests, such as tetracyanoquinodimethane, and can be used to tailor molecular receptors for specific applications.
EUROPEAN JOURNAL OF ORGANIC CHEMISTRY
(2021)
Article
Radiology, Nuclear Medicine & Medical Imaging
Joop A. Peters
CONTRAST MEDIA & MOLECULAR IMAGING
(2016)
Article
Chemistry, Multidisciplinary
Ina Hoffmann, Bettina Blumenroeder, Silvia Onodi Nee Thumann, Sabine Dommer, Juergen Schatz
Article
Chemistry, Inorganic & Nuclear
Susan Bartz, Daniel T. Schuhle, Joop A. Peters, Juergen Schatz
ZEITSCHRIFT FUR NATURFORSCHUNG SECTION B-A JOURNAL OF CHEMICAL SCIENCES
(2016)
Article
Biochemical Research Methods
Jakob Felix Hitzenberger, Agnes Uhl, Juergen Schatz, Thomas Drewello
JOURNAL OF MASS SPECTROMETRY
(2017)
Article
Chemistry, Physical
Bettina S. J. Heller, Claudia Kolbeck, Inga Niedermaier, Sabine Dommer, Juergen Schatz, Patricia Hunt, Florian Maier, Hans-Peter Steinrueck
Review
Chemistry, Inorganic & Nuclear
Joop A. Peters, Kristina Djanashvili, Carlos F. G. C. Geraldes, Carlos Platas-Iglesias
COORDINATION CHEMISTRY REVIEWS
(2020)
Article
Chemistry, Inorganic & Nuclear
Gina Zeh, Philipp Haines, Matthias E. Miehlich, Torben Kienz, Andreas Neidlinger, Ralf P. Friedrich, Huelya G. Oezkan, Christoph Alexiou, Frank Hampel, Dirk M. Guldi, Karsten Meyer, Juergen Schatz, Katja Heinze, Andriy Mokhir
Review
Chemistry, Physical
Joop A. Peters
PROGRESS IN NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY
(2020)
Review
Chemistry, Inorganic & Nuclear
Carlos F. G. C. Geraldes, M. Margarida C. A. Castro, Joop A. Peters
Summary: Mn(III) porphyrins show great potential as Gd-free MRI contrast agents due to their interesting redox properties and high affinity for tumor tissues. With applications in photothermal, photodynamic, and sonodynamic therapies, they are attractive for theranostics development. Their relative longitudinal relaxivity at typical clinical MRI field strengths is even higher than traditional Gd-based agents.
COORDINATION CHEMISTRY REVIEWS
(2021)
Review
Biochemistry & Molecular Biology
Carlos F. G. C. Geraldes, Joop A. Peters
Summary: Molecular recognition involving glycoprotein-mediated interactions is important in various medical applications, but visualizing these interactions and the extent of sugar expression is challenging.
Review
Chemistry, Inorganic & Nuclear
Joop A. Peters, Kristina Djanashvili
Summary: This review examines the chemical mechanisms of the interactions between boronic acids and N-acetylneuraminic acids, which have been widely used in biomedicine. It emphasizes that the affinity of boronic acids for N-acetylneuraminic acids is pH dependent and complementary to their affinity for other common monosaccharides. Various examples from the literature illustrate the unique pH profile of the boronic-N-acetylneuraminic acid interaction and its applications in biomedicine.
COORDINATION CHEMISTRY REVIEWS
(2023)
Review
Chemistry, Multidisciplinary
Sebastian Funk, Juergen Schatz
JOURNAL OF INCLUSION PHENOMENA AND MACROCYCLIC CHEMISTRY
(2020)
Article
Chemistry, Inorganic & Nuclear
Joop A. Peters, Carlos E. G. C. Geraldes
Article
Nanoscience & Nanotechnology
Wuyuan Zhang, Jonathan Martinelli, Joop A. Peters, Jacob M. A. van Hengst, Hans Bouwmeester, Evelien Kramer, Celia S. Bonnet, Frederic Szeremeta, Eva Toth, Kristina Djanashvili
ACS APPLIED MATERIALS & INTERFACES
(2017)
Review
Chemistry, Inorganic & Nuclear
Pegah Hajivand, Johannes Carolus Jansen, Emilio Pardo, Donatella Armentano, Teresa F. Mastropietro, Amirreza Azadmehr
Summary: VOCs in human breath can be used as biomarkers for diseases, and MOFs have been extensively studied as gas sensors for VOCs. This review provides a comprehensive summary of the latest MOF-derived composites used as VOCs biomarkers' sensors, and discusses the structural and functional characteristics of MOFs, sensing properties, and the potential of bio-MOFs in VOCs sensing.
COORDINATION CHEMISTRY REVIEWS
(2024)
Review
Chemistry, Inorganic & Nuclear
Seoyoon Song, Deborah Lee, Lucia C. Dalle Ore, Sungjun Kwak, Lifeng Kang, Hyung Kyo Kim, Noah Malmstadt, Sun Min Kim, Tae-Joon Jeon
Summary: This paper introduces the latest advancements in photoactivable liposomes in drug delivery, highlighting their advantages in precise control over drug release and targeted delivery, as well as the fine control over release kinetics achieved through the manipulation of light-responsive components. Additionally, the paper emphasizes the design considerations of physicochemical properties and light-related constituents.
COORDINATION CHEMISTRY REVIEWS
(2024)
Review
Chemistry, Inorganic & Nuclear
Shudi Liu, Liangwei Zhang, Heejeong Kim, Jinyu Sun, Juyoung Yoon
Summary: Chromium is a strategic and critical transition metal element with extensive applications. Efficient detection methods, such as fluorescence and colorimetry, have been developed for monitoring its concentrations. However, existing reviews on fluorescent probes for chromium lack comprehensive coverage. This review aims to consolidate information and promote the development of novel fluorescent probes for chromium detection.
COORDINATION CHEMISTRY REVIEWS
(2024)
Review
Chemistry, Inorganic & Nuclear
Rehab H. Elattar, Samah F. El-Malla, Amira H. Kamal, Fotouh R. Mansour
Summary: Metal complexes have strong analysis potential and can be used to measure analytes lacking essential chemical properties. Their analytical methods based on different mechanisms offer superior performance.
COORDINATION CHEMISTRY REVIEWS
(2024)
Review
Chemistry, Inorganic & Nuclear
Nem Singh, Miae Won, Yunjie Xu, Changyu Yoon, Jiyoung Yoo, Mingle Li, Heemin Kang, Jong Seung Kim
Summary: Hypoxia is a common occurrence in the tumor microenvironment and poses challenges for cancer treatment. The introduction of covalent organic frameworks (COFs) offers promising prospects for addressing hypoxia-related issues. This article explores the role of COFs in enhancing oxygen delivery, generating reactive oxygen species, optimizing drug delivery, and enabling hypoxia-specific imaging, as well as outlining their applications in various hypoxia-targeting therapeutic modalities.
COORDINATION CHEMISTRY REVIEWS
(2024)
Review
Chemistry, Inorganic & Nuclear
Priyadarshi Roy Chowdhury, Himani Medhi, Krishna G. Bhattacharyya, Chaudhery Mustansar Hussain
Summary: This review critically analyzes the production of waste-derived layered double hydroxides (LDH) and their utility in electrochemical water splitting for the generation of green hydrogen as sustainable energy. It highlights the importance of waste-derived LDH and discusses the challenges and future directions in this field.
COORDINATION CHEMISTRY REVIEWS
(2024)
Review
Chemistry, Inorganic & Nuclear
Rajamanickam Sivakumar, Nae Yoon Lee
Summary: This article reviews the progress in imaging reactive oxygen, nitrogen, and sulfur species (RONSS) using luminescent metal complex-based probes. This technology is selective and sensitive, which is of great significance for studying the impact of RONSS in cells and tissues and preventing diseases.
COORDINATION CHEMISTRY REVIEWS
(2024)
Review
Chemistry, Inorganic & Nuclear
Xinyang Li, Binbin Ding, Pan Zheng, Ping'an Ma, Jun Lin
Summary: The main goal of immunotherapy is to enhance the response and cytotoxicity of tumor-specific T cells by turning cold tumors into hot tumors. However, metabolic reprogramming in the tumor microenvironment can depress the cytotoxicity of T cells and hinder the effectiveness of immunotherapy. This review discusses the role of metabolic reprogramming in the interplay between cancer cells and immune cells in the tumor microenvironment and explores the use of nanomaterials to modulate metabolic pathways and improve immunotherapy outcomes.
COORDINATION CHEMISTRY REVIEWS
(2024)
Review
Chemistry, Inorganic & Nuclear
Kingsley Poon, Abhishek Gupta, William S. Price, Hala Zreiqat, Gurvinder Singh
Summary: Progress in the development of manganese oxide nanoparticles (MONPs) has provided an alternative for early-stage diagnosis of life-threatening diseases and therapeutic delivery of drugs and genes. The synthesis and characterization of MONPs have enabled the production of multi-functional targeted nanoparticles in various sizes and shapes. The integration of diagnosis and therapeutic capabilities within a single entity, known as nanotheranostics, is promising for real-time monitoring of disease progression and evaluating therapeutic treatment efficacy.
COORDINATION CHEMISTRY REVIEWS
(2024)
Review
Chemistry, Inorganic & Nuclear
Reza Abedi-Firoozjah, Hadiseh Ebdali, Mahya Soltani, Parastoo Abdolahi-Fard, Mahshid Heydari, Elham Assadpour, Maryam Azizi-Lalabadi, Fuyuan Zhang, Seid Mahdi Jafari
Summary: With the increasing awareness of food safety, there is a growing demand for efficient and affordable sensing methods for the detection of pathogens and toxins in food products. Nanosensors offer promising solutions with their quick and reliable detection capabilities, although challenges remain in their fabrication and practical application.
COORDINATION CHEMISTRY REVIEWS
(2024)
Review
Chemistry, Inorganic & Nuclear
Demei Sun, Xuesong Feng, Xinyuan Zhu, Youfu Wang, Jinghui Yang
Summary: Metal organic cages (MOCs) with precise and tunable nano structures show great potential in cancer therapy. Their diverse functions and ultrasmall size make them excellent nanoagents for different anticancer strategies, demonstrating outstanding anticancer performances.
COORDINATION CHEMISTRY REVIEWS
(2024)
Review
Chemistry, Inorganic & Nuclear
Li Li, Yang-Tao Yu, Ning-Ning Zhang, Shu-Hao Li, Jian-Ge Zeng, Yang Hua, Hong Zhang
Summary: This article summarizes recent advances in POM-based hybrid photochromic materials (PCHPMs), including structure types, new photochromic mechanisms, and applications. It can provide valuable guidance for researchers investigating POM-based hybrid photochromic materials.
COORDINATION CHEMISTRY REVIEWS
(2024)
Review
Chemistry, Inorganic & Nuclear
Chien Ing Yeo, Clariss Hui Peng Goh, Edward R. T. Tiekink, Jactty Chew
Summary: This review article provides an overview of the antibacterial activity of gold complexes, with a focus on gold(I) and gold(III) complexes. It also summarizes the repurposing of Auranofin for antibacterial purposes and the associated mechanism(s) of action.
COORDINATION CHEMISTRY REVIEWS
(2024)
Review
Chemistry, Inorganic & Nuclear
Sangharaj Diyali, Nilankar Diyali, Bhaskar Biswas
Summary: This study discusses the recent progress in the design and development of catalysts, focusing on the factors influencing overpotential, catalytic rate, and stability, as well as the mechanisms of the hydrogen evolution reaction in acidic and alkaline media. Moreover, it outlines the challenges in future design of robust and active electrocatalysts.
COORDINATION CHEMISTRY REVIEWS
(2024)
Review
Chemistry, Inorganic & Nuclear
Shaik Gouse Peera, Rahul S. Menon, Sumanta Kumar Das, Akram Alfantazi, K. Karuppasamy, Chao Liu, Akhila Kumar Sahu
Summary: Doped carbon materials, especially F-doped carbon catalysts, have gained significant attention as metal-free catalysts for oxygen reduction reactions and as corrosion-resistant supports for Pt and non-Pt nanoparticles. F-doped carbon materials possess unique properties and greatly improve the activity and durability of the ORR compared to N-doped carbon materials. The high electronegativity of F-doping can efficiently modify the electronic band structure of carbon materials, favoring the ORR. This review systematically discusses the effect of F-doping/F co-doping on the electrocatalytic reduction of O2 in acidic and alkaline conditions, the stability and durability of fuel cell catalysts, and provides guidelines for working with F-doped carbons. Future research directions on F-doped carbons are also proposed to bridge the gap between laboratory-scale assessments and commercial applications.
COORDINATION CHEMISTRY REVIEWS
(2024)