Article
Obstetrics & Gynecology
Pleun Beelen, Marian J. van den Brink, Malou C. Herman, Peggy M. A. J. Geomini, Janny H. Dekker, Ruben G. Duijnhoven, Nienke Mak, Hannah S. van Meurs, Sjors F. Coppus, Jan Willem van der Steeg, Heleen P. Eising, Diana S. Massop-Helmink, Ellen R. Klinkert, Theodoor E. Nieboer, Anne Timmermans, Lucet F. van der Voet, Sebastiaan Veersema, Nicol A. C. Smeets, Joke M. Schutte, Marchien van Baal, Patrick M. Bossuyt, Ben Willem J. Mol, Marjolein Y. Berger, Marlies Y. Bongers
Summary: This study compared the effectiveness of the levonorgestrel-releasing intrauterine system with endometrial ablation in women with heavy menstrual bleeding. Both treatments led to a significant decrease in menstrual blood loss and similar quality of life scores post-treatment, but endometrial ablation showed a significant advantage in reducing menstrual blood loss.
AMERICAN JOURNAL OF OBSTETRICS AND GYNECOLOGY
(2021)
Article
Radiology, Nuclear Medicine & Medical Imaging
Luisa Charlotte Huck, Daniel Truhn, Caroline Wilpert, Eloisa Zanderigo, Vanessa Raaff, Ebba Dethlefsen, Maike Bode, Christiane Katharina Kuhl
Summary: This study analyzed the association between the use of levonorgestrel-releasing intrauterine contraceptive devices (LNG-IUDs) and benign background parenchymal enhancement (BPE) in breast dynamic contrast-enhanced (DCE) MRI. The results showed that the use of LNG-IUDs can be associated with increased BPE in breast MRI, providing further evidence that LNG-IUDs do have systemic effects.
EUROPEAN RADIOLOGY
(2022)
Review
Obstetrics & Gynecology
Tamara J. Oderkerk, Majorie M. A. van de Kar, Carlijn H. M. van Der Zanden, Peggy M. A. J. Geomini, Malou C. Herman, Marlies Y. Bongers
Summary: Immediately inserting a levonorgestrel-intrauterine system (LNG-IUS) after endometrial ablation/resection seems to reduce the need for re-intervention and hysterectomy rates, and improve patient satisfaction. However, limited observational studies with low methodological quality are currently available, highlighting the need for higher quality research to confirm these findings.
ACTA OBSTETRICIA ET GYNECOLOGICA SCANDINAVICA
(2021)
Article
Obstetrics & Gynecology
Chihiro Ishizawa, Yasushi Hirota, Rei Iida, Tetsuaki Kaku, Tomoyuki Hirata, Yamato Fukui, Erika Omura, Shun Akaeda, Takehiro Hiraoka, Mitsunori Matsuo, Yutaka Osuga
Summary: This study aimed to investigate the efficacy of levonorgestrel-releasing intrauterine system (LNG-IUS) in improving menorrhagia-specific health-related quality of life (HR-QOL) in patients with symptomatic adenomyosis. The study found that LNG-IUS treatment effectively improved menorrhagia-specific HR-QOL in patients with incipient type adenomyosis, but its efficacy was decreased in patients with advanced type adenomyosis. LNG-IUS treatment also improved blood hemoglobin levels in incipient type adenomyosis but not in advanced type. Dysmenorrhea and heavy menstrual bleeding (HMB)-related anemia were associated with HR-QOL impairment, and LNG-IUS treatment may relieve these symptoms and improve HR-QOL. The use of magnetic resonance imaging should be reinforced to predict LNG-IUS efficacy in improving HR-QOL in patients with adenomyosis.
REPRODUCTIVE SCIENCES
(2023)
Article
Medicine, General & Internal
Hye Yun Kim, Soo Youn Song, Soo Hwa Jung, Hyun Jeong Song, Mina Lee, Ki Hwan Lee, Ye Won Jung, Heon Jong Yoo
Summary: This study suggests that using levonorgestrel releasing intrauterine system (LNG-IUS) for >5 years as postoperative maintenance therapy for endometriosis patients can significantly reduce pain with less systemic side effects compared to other treatments.
Review
Medicine, General & Internal
Paola Bianchi, Sun-Wei Guo, Marwan Habiba, Giuseppe Benagiano
Summary: This literature review examines the use of levonorgestrel-releasing intrauterine devices for heavy menstrual bleeding and/or dysmenorrhea. The review highlights that the insertion of a levonorgestrel-releasing intrauterine system is a useful option for long-term treatment, improving the quality of life and reducing menstrual blood loss and dysmenorrhea symptoms. Its ability to induce amenorrhea is considered to be the most important mechanism of action.
JOURNAL OF CLINICAL MEDICINE
(2022)
Article
Obstetrics & Gynecology
Montas Laporte, Charles M. Charles, Sherly Metelus, Alessandra Peloggia, Gabriela de O. Paez, Cassia T. Juliato, Luis Bahamondes
Summary: This study aimed to assess the reasons why women choose the 52mg levonorgestrel intrauterine system as a contraceptive method. The main reasons reported were safety, high contraceptive efficacy, and reduction in menstrual bleeding, indicating the importance of educating healthcare providers and promoting awareness among women about the benefits of the LNG-IUS for contraception.
INTERNATIONAL JOURNAL OF GYNECOLOGY & OBSTETRICS
(2022)
Article
Medicine, General & Internal
Vidya Gaikwad, Sanjay Ponde, Suneha Yalla, Suhas Gaikwad
Summary: Contraceptive methods have evolved over time and the most commonly used one is oral contraceptive pills. Besides contraception, these pills are also used for treating various gynaecological disorders. However, the use of oral contraceptive pills has been associated with a higher risk of intracranial hemorrhage and stroke. This case report highlights a patient who took these pills irrationally for a long period of time and presented with symptoms suggestive of hemorrhagic stroke.
CUREUS JOURNAL OF MEDICAL SCIENCE
(2023)
Article
Endocrinology & Metabolism
Limei Ji, Lanying Jin, Ming Jun Shao, Min Hu, JIan Xu
Summary: This study aimed to compare the reproductive hormone levels and metabolic variables in patients with PCOS treated with LNG-IUS. The results showed that LNG-IUS did not significantly impact the clinical and metabolic variables in PCOS patients and healthy controls.
GYNECOLOGICAL ENDOCRINOLOGY
(2023)
Review
Obstetrics & Gynecology
Aline Zurcher, Laura Knabben, Heidrun Janka, Petra Stute
Summary: This systematic review analyzed the literature on breast cancer and the use of the levonorgestrel-releasing intrauterine system (LNG-IUS). The results suggest an increased risk of breast cancer in LNG-IUS users, especially in postmenopausal women and with longer duration of use. However, the heterogeneity of the studies and various confounding factors call for further investigations.
ARCHIVES OF GYNECOLOGY AND OBSTETRICS
(2023)
Article
Endocrinology & Metabolism
Krzysztof Nowosielski
Summary: The study found differences in sexual behaviors and function in women using oral combined contraceptive pills compared to nonusers, as well as varying impacts on body image, sexual problems, and sexual dysfunction. However, the use of oral combined contraceptive pills was not identified as a risk factor for worse sexual function or sexual dysfunction.
REPRODUCTIVE BIOLOGY AND ENDOCRINOLOGY
(2022)
Article
Medicine, General & Internal
Guo-Rui Zhang, Xin Yu
Summary: Perforation of LNG-IUS one month after placement is rare and requires laparoscopic surgery for removal. Ultrasound monitoring is recommended when the operation is difficult to reduce the risk of IUD perforation. Postoperative imaging is recommended for patients with inadequate surgery to detect potential risks as soon as possible.
WORLD JOURNAL OF CLINICAL CASES
(2023)
Review
Peripheral Vascular Disease
Natalie A. Cameron, Ciantel A. Blyler, Natalie A. Bello
Summary: Oral contraceptive pills (OCPs) are widely used as effective contraception, but they have a certain association with hypertension. Understanding the relationship between OCPs and hypertension is crucial for assessing the risks and benefits of use, and making individualized contraceptive decisions in light of the increasing prevalence of hypertension.
Article
Obstetrics & Gynecology
Jarbas Magalhaes, Edson Santos Ferreira-Filho, Jose Maria Soares-Junior, Edmund Chada Baracat
Summary: This study evaluated the effectiveness of LNG-IUS in treating abnormal uterine bleeding caused by different factors. The results showed that LNG-IUS effectively controlled uterine bleeding and reduced uterine volume. Additionally, the initial uterine volume was found to be an important factor for treatment adherence and outcomes.
EUROPEAN JOURNAL OF OBSTETRICS & GYNECOLOGY AND REPRODUCTIVE BIOLOGY
(2022)
Editorial Material
Obstetrics & Gynecology
Linling Zhu, Xinyun Yang, Benben Cao, Shanshan Tang, Jinyi Tong
Summary: The study demonstrated the feasibility and value of using the hysteroscopic cold-knife surgery system (HCSS) to fix a levonorgestrel-releasing intrauterine device (LNG-IUD) for treatment of adenomyosis. Proficient endoscopic suturing is key to the success of the technique, which can provide effective treatment for patients and prevent the risk of IUD expulsion.
FERTILITY AND STERILITY
(2021)
Article
Obstetrics & Gynecology
Benjamin Yao, Emily Slopnick, David Sheyn, Graham Chapman, Sherif El-Nashar, Adonis Hijaz, Sangeeta Mahajan
Summary: This study found that the leading allegation of malpractice litigations for nonmesh POP surgery is negligence of surgery, with urinary tract injury being the most common complication. The jury often sided with the defendant physician. There was no significant difference in plaintiff awards or settlements by region or time.
FEMALE PELVIC MEDICINE AND RECONSTRUCTIVE SURGERY
(2021)
Article
Obstetrics & Gynecology
Emily A. Slopnick, Graham C. Chapman, Kasey Roberts, David D. Sheyn, Sherif El-Nashar, Sangeeta T. Mahajan
Summary: A study was conducted to assess the national utilization of apical suspension procedures for the surgical treatment of complete pelvic organ prolapse (POP). The results showed that apical suspension procedures were performed in 46.7% of patients, with a higher rate in post-hysterectomy cases. Colpocleisis was more common in older age groups, post-hysterectomy cases, and those with higher comorbidity indexes.
INTERNATIONAL UROGYNECOLOGY JOURNAL
(2021)
Article
Obstetrics & Gynecology
Sonia Carlson, Sadhvi Batra, Megan Billow, Sherif A. El-Nashar, Graham Chapman
Summary: A study compared complications in patients undergoing laparoscopic vs open surgery for acute pelvic inflammatory disease (PID) and found that laparoscopy was associated with lower complication rates in a well-matched cohort of patients.
JOURNAL OF MINIMALLY INVASIVE GYNECOLOGY
(2021)
Article
Obstetrics & Gynecology
David Sheyn, Nicole M. Martin, Lucas Walden, Kasey M. Roberts, Sherif El-Nashar, Adonis K. Hijaz, Jeffrey W. Prescott
Summary: This study revealed measurable volumetric differences in brain structures between responders (R) and nonresponders (NR) to anticholinergic (AC) therapy for overactive bladder (OAB). Nonresponders exhibited lower volumes of specific brain regions compared to responders, and there were correlations between brain structure volumes and symptom severity.
FEMALE PELVIC MEDICINE AND RECONSTRUCTIVE SURGERY
(2021)
Article
Obstetrics & Gynecology
Emily A. Slopnick, Kasey Roberts, David D. Sheyn, Graham C. Chapman, Sherif El-Nashar, Sangeeta T. Mahajan
Summary: The study found that total hysterectomy is more common than subtotal hysterectomy during concurrent sacrocolpopexy, and the overall risk of complications is low with similar rates between the two types of hysterectomy.
FEMALE PELVIC MEDICINE AND RECONSTRUCTIVE SURGERY
(2021)
Review
Obstetrics & Gynecology
Olivia Thornton, Emily Daggett, Lyba Zia, Anna Quian, Emma Close, Leena Khaitan, Sherif A. El-Nashar, Maria Shaker
Summary: Through reviewing the medical records of bariatric surgery patients, the study found that over half of the patients did not use contraception after surgery, leading to a 6% pregnancy rate within 18 months postoperatively.
Article
Obstetrics & Gynecology
Ghanshyam S. Yadav, Graham C. Chapman, Rubin Raju, Sherif A. El-Nashar, John A. Occhino
Summary: The study compared perioperative outcomes of different reconstructive approaches for apical prolapse surgery in women aged 80 years or older and found that abdominal sacrocolpopexy had higher perioperative morbidity compared to vaginal colpopexy and minimally invasive sacrocolpopexy. Vaginal colpopexy was overall the safest approach in this elderly population.
INTERNATIONAL UROGYNECOLOGY JOURNAL
(2021)
Article
Obstetrics & Gynecology
Graham C. Chapman, Emily A. Slopnick, Kasey Roberts, David Sheyn, Sherif A. El-Nashar, Jeffrey M. Mangel, Adonis K. Hijaz
Summary: In elderly patients aged 80 years or older, there was no difference in overall complication rates between reconstructive surgery and obliterative surgery. However, propensity score matching revealed that patients who underwent reconstructive surgery had a higher risk of severe complications.
FEMALE PELVIC MEDICINE AND RECONSTRUCTIVE SURGERY
(2021)
Article
Obstetrics & Gynecology
Sadhvi Batra, Sarah A. Kennedy, Frank Tu, Sherif A. El-Nashar, John Nakayama
Summary: The COVID-19 pandemic has led to changes in gynecology practice patterns, with most institutions increasing social-distancing efforts and encouraging the use of personal protective equipment. Elective surgeries were cancelled, telemedicine was utilized, and patients were found to delay needed care according to a survey of gynecologists.
JOURNAL OF GYNECOLOGIC SURGERY
(2022)
Article
Obstetrics & Gynecology
John M. Nakayama, David Sheyn, Amr Mahran, Sherif A. El-Nashar
Summary: The study found that gynecologic procedures accounted for 6.8% of all surgical procedures from 2010 to 2015 and remained stable during the study period. The top 10% of procedures made up around 70% of all procedures, while the top 40% constituted approximately 97% of all procedures. Additionally, there was a significant trend towards an increase in total laparoscopic hysterectomy (TLH) and a decrease in total vaginal hysterectomy (TVH) and abdominal hysterectomy, potentially reflecting a shift in surgical practices.
JOURNAL OF GYNECOLOGIC SURGERY
(2021)
Article
Obstetrics & Gynecology
John Nakayama, Karen Ashby, Susan Wherley, Christa Dominick, Gi-Ming Wang, Curtis Tatsuoka, Sherif El-Nashar, Steven Waggoner
Summary: The study aimed to assess the effectiveness of antislip surfaces in reducing intraoperative patient displacement in the Trendelenburg position. Pink pad was found to significantly reduce movement and facilitate faster positioning compared to gel pad, with less postoperative back pain. Obesity was identified as a major predictor of movement, and pink pad was associated with significantly less postoperative erythema compared to the beanbag.
JOURNAL OF GYNECOLOGIC SURGERY
(2022)
Review
Obstetrics & Gynecology
Nina Rivera, Allison B. Reid, Maria Phillis, Sherif A. El-Nashar
Summary: The aim of this study was to estimate the incidence and time to diagnosis of postmolar gestational trophoblastic neoplasia (GTN) following uterine evacuation and normalization of human chorionic gonadotropin (hCG). The study found that the overall incidence of postmolar GTN after hCG normalization was low, and when it did occur, it often presented well beyond the recommended surveillance time periods.
JOURNAL OF GYNECOLOGIC SURGERY
(2022)
Article
Obstetrics & Gynecology
John Nakayama, Emi Hayashi, Mark Shahin, Sarah DeLozier, Sherif A. El-Nashar
Summary: This research evaluated trends in gynecologic surgical reimbursement, finding that overall gynecologic surgical billing remained flat while reimbursement for laparoscopic hysterectomy decreased. The study suggests that increasing the assigned relative value unit for high-volume procedures is the most effective method to maintain or improve overall gynecologic surgical compensation.
JOURNAL OF GYNECOLOGIC SURGERY
(2021)
Letter
Obstetrics & Gynecology
Julia Cook, Megha Gupta, John Nakayama, Sherif El-Nashar, Joshua Kesterson, Stephen Wagner
AMERICAN JOURNAL OF OBSTETRICS & GYNECOLOGY MFM
(2021)
Meeting Abstract
Urology & Nephrology
Anood Alfahmy, Amr Mahran, Britt Conroy, Rosemary Brewka, David Sheyn, Sherif El-Nashar, Adonis Hijaz, Anood Alfahmy
NEUROUROLOGY AND URODYNAMICS
(2021)