Spinal and Bulbar Muscular Atrophy Overview

Silencing neuronal mutant androgen receptor in a mouse model of spinal and bulbar muscular atrophy

(2015) Kentaro Sahashi et al.   HUMAN MOLECULAR GENETICS

Pioglitazone suppresses neuronal and muscular degeneration caused by polyglutamine-expanded androgen receptors

(2014) Madoka Iida et al.   HUMAN MOLECULAR GENETICS

Polyglutamine-expanded androgen receptor interferes with TFEB to elicit autophagy defects in SBMA

(2014) Constanza J Cortes et al.   NATURE NEUROSCIENCE

Stem cell-derived motor neurons from spinal and bulbar muscular atrophy patients

(2014) Christopher Grunseich et al.   NEUROBIOLOGY OF DISEASE

Early onset and novel features in a spinal and bulbar muscular atrophy patient with a 68 CAG repeat

(2014) Christopher Grunseich et al.   NEUROMUSCULAR DISORDERS

Muscle Expression of Mutant Androgen Receptor Accounts for Systemic and Motor Neuron Disease Phenotypes in Spinal and Bulbar Muscular Atrophy

(2014) Constanza J. Cortes et al.   NEURON

Muscle Matters in Kennedy’s Disease

(2014) Carlo Rinaldi et al.   NEURON

Peripheral Androgen Receptor Gene Suppression Rescues Disease in Mouse Models of Spinal and Bulbar Muscular Atrophy

(2014) Andrew P. Lieberman et al.   Cell Reports

Transcriptional activation of TFEB/ZKSCAN3 target genes underlies enhanced autophagy in spinobulbar muscular atrophy

(2013) J. P. Chua et al.   HUMAN MOLECULAR GENETICS

p62/SQSTM1 Differentially Removes the Toxic Mutant Androgen Receptor via Autophagy and Inclusion Formation in a Spinal and Bulbar Muscular Atrophy Mouse Model

(2013) H. Doi et al.   JOURNAL OF NEUROSCIENCE

Unknown

(2013) Carlo Rinaldi et al.   MOLECULAR MEDICINE

A role for androgen reduction treatment in kennedy disease?

(2013) Kenneth H. Fischbeck   MUSCLE & NERVE

Viral delivery of miR-196a ameliorates the SBMA phenotype via the silencing of CELF2

(2012) Yu Miyazaki et al.   NATURE MEDICINE

Naratriptan mitigates CGRP1-associated motor neuron degeneration caused by an expanded polyglutamine repeat tract

(2012) Makoto Minamiyama et al.   NATURE MEDICINE

Efficacy and safety of dutasteride in patients with spinal and bulbar muscular atrophy: a randomised placebo-controlled trial

(2011) Lindsay E Fernández-Rhodes et al.   LANCET NEUROLOGY

Efficacy and safety of leuprorelin in patients with spinal and bulbar muscular atrophy (JASMITT study): a multicentre, randomised, double-blind, placebo-controlled trial

(2010) Masahisa Katsuno et al.   LANCET NEUROLOGY

Phase 2 trial of leuprorelin in patients with spinal and bulbar muscular atrophy

(2009) Haruhiko Banno et al.   ANNALS OF NEUROLOGY

Overexpression of IGF-1 in Muscle Attenuates Disease in a Mouse Model of Spinal and Bulbar Muscular Atrophy

(2009) Isabella Palazzolo et al.   NEURON