Arginase-1 deficiency

Human recombinant arginase enzyme reduces plasma arginine in mouse models of arginase deficiency

(2015) Lindsay C. Burrage et al.   HUMAN MOLECULAR GENETICS

Therapeutic genome editing: prospects and challenges

(2015) David Benjamin Turitz Cox et al.   NATURE MEDICINE

Arginase: an old enzyme with new tricks

(2015) Ruth B. Caldwell et al.   TRENDS IN PHARMACOLOGICAL SCIENCES

Strategies to Rescue the Consequences of Inducible Arginase-1 Deficiency in Mice

(2015) Laurel L. Ballantyne et al.   PLoS One

Treatment of arginase deficiency revisited: guanidinoacetate as a therapeutic target and biomarker for therapeutic monitoring

(2014) Wajdi Amayreh et al.   DEVELOPMENTAL MEDICINE AND CHILD NEUROLOGY

Significant Hepatic Involvement in Patients with Ornithine Transcarbamylase Deficiency

(2014) Renata C. Gallagher et al.   JOURNAL OF PEDIATRICS

Arginase-1 Deficiency Regulates Arginine Concentrations and NOS2-Mediated NO Production during Endotoxemia

(2014) Karolina A. P. Wijnands et al.   PLoS One

AAV-based gene therapy prevents neuropathology and results in normal cognitive development in the hyperargininemic mouse

(2013) E K Lee et al.   GENE THERAPY

Subpopulations of myeloid-derived suppressor cells impair T cell responses through independent nitric oxide-related pathways

(2013) Patrick L. Raber et al.   INTERNATIONAL JOURNAL OF CANCER

A Cut above the Rest: Targeted Genome Editing Technologies in Human Pluripotent Stem Cells

(2013) Mo Li et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Lethal phenotype in conditional late-onset arginase 1 deficiency in the mouse

(2013) Jennifer Kasten et al.   MOLECULAR GENETICS AND METABOLISM

The incidence of urea cycle disorders

(2013) Marshall L. Summar et al.   MOLECULAR GENETICS AND METABOLISM

Inducible Arginase 1 Deficiency in Mice Leads to Hyperargininemia and Altered Amino Acid Metabolism

(2013) Yuan Yan Sin et al.   PLoS One

Analysis of novel ARG1 mutations causing hyperargininemia and correlation with arginase I activity in erythrocytes

(2012) Daniel Rocha Carvalho et al.   GENE

Metabolism of L-Arginine by Myeloid-Derived Suppressor Cells in Cancer: Mechanisms of T cell suppression and Therapeutic Perspectives

(2012) Patrick Raber et al.   IMMUNOLOGICAL INVESTIGATIONS

Long-term Survival of the Juvenile Lethal Arginase-deficient Mouse With AAV Gene Therapy

(2012) Eun K. Lee et al.   MOLECULAR THERAPY

Suggested guidelines for the diagnosis and management of urea cycle disorders

(2012) Johannes Häberle et al.   Orphanet Journal of Rare Diseases

Arginase Deficiency With New Phenotype and a Novel Mutation: Contemporary Summary

(2012) Jane Pui Ki Tsang et al.   PEDIATRIC NEUROLOGY

Tamoxifen Induces Rapid, Reversible Atrophy, and Metaplasia in Mouse Stomach

(2011) Won Jae Huh et al.   GASTROENTEROLOGY

Regulation of Macrophage Arginase Expression and Tumor Growth by the Ron Receptor Tyrosine Kinase

(2011) D. R. Sharda et al.   JOURNAL OF IMMUNOLOGY

Arginase I deficiency: Severe infantile presentation with hyperammonemia: More common than reported?

(2011) Shailly Jain-Ghai et al.   MOLECULAR GENETICS AND METABOLISM

Argininemia Presenting With Progressive Spastic Diplegia

(2011) Beom Hee Lee et al.   PEDIATRIC NEUROLOGY

A long-term survival case of arginase deficiency with severe multicystic white matter and compound mutations

(2010) Yoshie Segawa et al.   BRAIN & DEVELOPMENT

Arginase deficiency in multiple tissues in argininemia

(2010) Virginia V. Michels et al.   CLINICAL GENETICS

Beneficial effects of high dose of L-arginine on airway hyperresponsiveness and airway inflammation in a murine model of asthma

(2010) Ulaganathan Mabalirajan et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Guanidino compound levels in blood, cerebrospinal fluid, and post-mortem brain material of patients with argininemia

(2010) Joshua L. Deignan et al.   MOLECULAR GENETICS AND METABOLISM

Functionally important role for arginase 1 in the airway hyperresponsiveness of asthma

(2009) Michelle L. North et al.   AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY

Arginase: a key enzyme in the pathophysiology of allergic asthma opening novel therapeutic perspectives

(2009) Harm Maarsingh et al.   BRITISH JOURNAL OF PHARMACOLOGY

Long-term neurodevelopmental effects of early detection and treatment in a 6-year-old patient with argininaemia diagnosed by newborn screening

(2009) R. L. Edwards et al.   JOURNAL OF INHERITED METABOLIC DISEASE

Early-onset hyperargininaemia: A severe disorder?

(2009) M. Schiff et al.   JOURNAL OF INHERITED METABOLIC DISEASE

Neuroimaging Findings in Hyperargininemia

(2009) Serdal Güngör et al.   JOURNAL OF NEUROIMAGING

Short-term Correction of Arginase Deficiency in a Neonatal Murine Model With a Helper-dependent Adenoviral Vector

(2009) Chia-Ling Gau et al.   MOLECULAR THERAPY

Amino acids in CSF and plasma in hyperammonaemic coma due to arginase1 deficiency

(2008) S. Scholl-Bürgi et al.   JOURNAL OF INHERITED METABOLIC DISEASE

Increased plasma and tissue guanidino compounds in a mouse model of hyperargininemia

(2007) Joshua L. Deignan et al.   MOLECULAR GENETICS AND METABOLISM