期刊
ANIMAL GENETICS
卷 50, 期 2, 页码 175-176出版社
WILEY
DOI: 10.1111/age.12346
关键词
Bonferroni-corrected P-value; GWAS; integrator complex subunit 6; LIM domain binding 2
资金
- National Broiler Industrial and Technology System [nycytx-42-G1-05]
- Priority Academic Program Development of Jiangsu Higher Education Institutions
- Graduate Education Innovation Project in Jiangsu Province [CXLX12_0930]
In this study, we performed a new genome-wide association study using SLAF-seq technology. A total of 19 single nucleotide polymorphism effects involving nine different SNP markers reached 5% Bonferroni-corrected genome-wide significance. In addition, a 5-Mb region spanning 72.9-77.9 Mb on GGA4, exhibiting many significant SNP effects, was identified. The LDB2 gene in this region had a very strong association with body weight. Another SNP on GGA1, located in the INTS6 gene, had the strongest association with late body weight (weeks 10-16). Some of the SNPs that reached suggestive significance level overlapped with previously reported quantitative trait locus regions.
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