Article
Engineering, Biomedical
Kimberly R. Kroupa, Lianna R. Gangi, Brandon K. Zimmerman, Clark T. Hung, Gerard A. Ateshian
Summary: Recent studies have shown that superficial zone chondrocytes within ar-ticular layers of diarthrodial joints die under normal physiologic loading conditions. In order to understand the mechanical environment that causes their death, a multiscale finite element analysis was conducted to track the changes in interstitial fluid pressure, hydraulic permeability, and volume of SZ chondrocytes under loading. The results indicated that sustained physiological loading can lead to significant loss of intracellular fluid volume, hindering cellular metabolic activity and fluid transport properties.
ACTA BIOMATERIALIA
(2023)
Review
Chemistry, Multidisciplinary
Alexander Paz, Gustavo A. Orozco, Rami K. Korhonen, Jose J. Garcia, Mika E. Mononen
Summary: Osteoarthritis is a degenerative disease lacking a cure, prompting researchers to utilize computational methods like finite element analysis to simulate risks and evaluate prevention measures. Current trends in clinical studies for knee OA emphasize speeding up analysis for personalized risk predictions.
APPLIED SCIENCES-BASEL
(2021)
Article
Biotechnology & Applied Microbiology
Nynke B. Rooks, Thor F. Besier, Marco T. Y. Schneider
Summary: The reproducibility of computational knee joint modeling is questionable, and the influence of model variations on simulation outcomes should be investigated. This study conducted a parameter sensitivity analysis using multiple finite element knee joint models and found that the ligament material properties had a significant impact on model outcomes. The sensitivity of model parameters is model-dependent and cannot be assumed to be the same in other models.
FRONTIERS IN BIOENGINEERING AND BIOTECHNOLOGY
(2022)
Article
Engineering, Biomedical
Liming Shu, Takashi Sato, Xijin Hua, Naohiko Sugita
Summary: The study compared the kinematics and contact mechanics of four TKR designs and the normal knee joint, with the medial pivot design showing similar kinematics to the normal knee joint. The normal knee joint exhibited a larger contact area and lower contact pressure compared to the TKR designs, while the mobile CR and PS designs had the smallest and greatest contact pressures, respectively.
ANNALS OF BIOMEDICAL ENGINEERING
(2021)
Article
Multidisciplinary Sciences
Tong Liu, Xianyue Shen, Qingming Ji, Jianlin Xiao, Jianlin Zuo, Zhongli Gao
Summary: This study investigated the displacements and 3D morphological changes of knee menisci under weight-bearing and early flexion conditions in healthy adults using MRI technology. The research revealed that menisci showed different changes in morphological patterns under various flexion angles and external loading conditions, providing a valuable reference for evaluating meniscal integrity.
SCIENTIFIC REPORTS
(2021)
Article
Engineering, Biomedical
Junyan Li
Summary: Musculoskeletal models are crucial for biomechanical investigations, but deformable contact models of the hip are often overlooked. This study presents a new approach using finite element analysis to simulate hip joint movement within a musculoskeletal model, providing insights into hip contact mechanics.
JOURNAL OF THE MECHANICAL BEHAVIOR OF BIOMEDICAL MATERIALS
(2021)
Article
Engineering, Multidisciplinary
Alfredo Gay Neto
Summary: This paper proposes an integrated framework for handling and managing automatic contact detection in complex multibody systems. Both rigid and flexible bodies can be considered, and strategies such as MBD, FEM, and DEM can be employed. Pointwise contact interactions are modeled based on geometric descriptions and the master-master contact formulation. A hierarchy of bounding volumes is used for collision detection, and a local contact problem is solved to determine the contact point location. The proposed strategy is independent of MBD/FEM/DEM characteristics and can be used with different time integration solvers.
COMPUTER METHODS IN APPLIED MECHANICS AND ENGINEERING
(2023)
Article
Engineering, Mechanical
Huaidong Yang, Itzhak Green
Summary: This study develops a comprehensive adhesion model using finite element analysis for a deformable hemisphere under fretting conditions. The model combines normal adhesion based on JKR model and tangential resistance based on shear strength and surface free energy, implemented through interfacial bilinear springs. The research shows that while spring breakage may be gradual or avalanching, the tangential resistance effect is robust and not affected by meshing or spring settings, with significant plastic deformation and energy losses observed.
TRIBOLOGY INTERNATIONAL
(2021)
Article
Engineering, Mechanical
Michael Maier, Michael Pusterhofer, Florian Summer, Florian Gruen
Summary: This article compares various contact models and evaluates their applicability by comparing Stribeck curves. The study found that the elastic FEM contact model and the statistical model according to Greenwood and Tripp provide the best agreement with experimental data.
TRIBOLOGY INTERNATIONAL
(2022)
Article
Cell & Tissue Engineering
J. A. Lee, Y-G. Koh, P. S. Kim, J-H. Park, K-T. Kang
Summary: This study used finite element analysis to evaluate the mechanical behavior of cartilage surrounding a metal implant in focal knee arthroplasty. The contact stress and pressure on the medial and lateral femoral and tibial cartilages were compared for different implantation models. The results suggest that leaving the edge slightly deep is preferable to flush and protruding implantation.
BONE & JOINT RESEARCH
(2023)
Article
Engineering, Electrical & Electronic
Marco Cirelli, Alessio Cellupica, Luca D'Angelo, Marta Mazur, Pier Paolo Valentini
Summary: This study proposes a flexible multibody model and uses numerical simulation and experimental validation to assess the effectiveness of different toothbrush designs. The results demonstrate the accuracy of estimating the forces exerted by the bristles and evaluating their displacement during toothbrush motion. The suggested model could guide holistic toothbrush design and improve cleaning effectiveness.
Article
Engineering, Biomedical
Wael Alliliche, Christine Renaud, Jean-Michel Cros, Zhi-Qiang Feng
Summary: The skin is modeled using an improved constitutive law called HGO-Yeoh, which accounts for its hyperelastic and anisotropic behavior. The finite element code FER Finite Element Research is utilized to implement this model and benefit from its bipotential contact method. Material parameters related to the skin are identified through an optimization procedure using both analytic and experimental data. Tensile and indentation tests are simulated and compared with experimental results using the FER and ANSYS codes.
JOURNAL OF THE MECHANICAL BEHAVIOR OF BIOMEDICAL MATERIALS
(2023)
Article
Engineering, Civil
B. Iraola, J. M. Cabrero, M. Basterrechea-Arevalo, J. Gracia
Summary: This study addresses the issue of overestimation of the actual elastic response of structural timber connections by finite element models, proposing a control parameter called stiffness contact. The method for determining stiffness contact based on the geometry of a rectangular contact area is demonstrated through experimental campaigns on dowel embedment and moment resistant wood joint tests, showing good agreement with the experimental results.
ENGINEERING STRUCTURES
(2021)
Article
Engineering, Mechanical
Keisuke Otsuka, Yinan Wang, Koji Fujita, Hiroki Nagai, Kanjuro Makihara
Summary: This study developed a novel consistent strain-based multifidelity modeling framework to address the problems in conventional multifidelity modeling. By leveraging new vector-strain transformations, all fidelity models obtained from the proposed framework consistently use the same external force model. The framework was validated using a hydrodynamic force model, and the simulation results concurred with conventional models and experiments. The reduction in calculation time provided by low-fidelity models has significant implications for conceptual and initial designs.
JOURNAL OF COMPUTATIONAL AND NONLINEAR DYNAMICS
(2022)
Article
Engineering, Biomedical
Alexander Paz, Jose J. Garcia, Rami K. K. Korhonen, Mika E. E. Mononen
Summary: In this study, the transferability of a template-based modeling strategy was assessed by implementing it on two different finite element (FE) softwares. The results showed that the two softwares detected different volumes of overstressed tissue in corresponding knee samples, but achieved consistent classification between healthy joints and those with severe osteoarthritis.
ANNALS OF BIOMEDICAL ENGINEERING
(2023)