Molecular architecture of the bacterial tripartite multidrug efflux pump focusing on the adaptor bridging model

Functional analysis of Vibrio vulnificus RND efflux pumps homologous to Vibrio cholerae VexAB and VexCD, and to Escherichia coli AcrAB

(2015) Seunghwa Lee et al.   JOURNAL OF MICROBIOLOGY

Structure of the Tripartite Multidrug Efflux Pump AcrAB-TolC Suggests an Alternative Assembly Mode

(2015) Jin-Sik Kim et al.   MOLECULES AND CELLS

Assembly and operation of bacterial tripartite multidrug efflux pumps

(2015) Dijun Du et al.   TRENDS IN MICROBIOLOGY

Vibrio vulnificus VvhA induces NF-κB-dependent mitochondrial cell death via lipid raft-mediated ROS production in intestinal epithelial cells

(2015) S-J Lee et al.   Cell Death & Disease

Structural basis of RND-type multidrug exporters

(2015) Akihito Yamaguchi et al.   Frontiers in Microbiology

Molecular Mechanism of MBX2319 Inhibition of Escherichia coli AcrB Multidrug Efflux Pump and Comparison with Other Inhibitors

(2014) Attilio V. Vargiu et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Structure of the periplasmic adaptor protein from a major facilitator superfamily (MFS) multidrug efflux pump

(2014) Philip Hinchliffe et al.   FEBS LETTERS

Interaction between the α-barrel tip of Vibrio vulnificus TolC homologs and AcrA implies the adapter bridging model

(2014) Seunghwa Lee et al.   JOURNAL OF MICROBIOLOGY

Structure of the AcrAB–TolC multidrug efflux pump

(2014) Dijun Du et al.   NATURE

Interaction Mediated by the Putative Tip Regions of MdsA and MdsC in the Formation of a Salmonella-Specific Tripartite Efflux Pump

(2014) Saemee Song et al.   PLoS One

Protoporphyrin (PPIX) efflux by the MacAB-TolC pump inEscherichia coli

(2014) Evelyne Turlin et al.   MicrobiologyOpen

Structure and Operation of Bacterial Tripartite Pumps

(2013) Philip Hinchliffe et al.   Annual Review of Microbiology

The α-barrel tip region of Escherichia coli TolC homologs of Vibrio vulnificus interacts with the MacA protein to form the functional macrolide-specific efflux pump MacAB-TolC

(2013) Minho Lee et al.   JOURNAL OF MICROBIOLOGY

Selective inhibition of the unfolded protein response: targeting catalytic sites for Schiff base modification

(2013) Susana M. Tomasio et al.   Molecular BioSystems

The ABC-Type Efflux Pump MacAB Protects Salmonella enterica serovar Typhimurium from Oxidative Stress

(2013) L. M. Bogomolnaya et al.   mBio

MOLECULAR DYNAMICS COMPUTER SIMULATIONS OF MULTIDRUG RND EFFLUX PUMPS

(2013) Paolo Ruggerone et al.   Computational and Structural Biotechnology Journal

Assembly and Channel Opening of Outer Membrane Protein in Tripartite Drug Efflux Pumps of Gram-negative Bacteria

(2012) Yongbin Xu et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Membrane Fusion Proteins of Type I Secretion System and Tripartite Efflux Pumps Share a Binding Motif for TolC in Gram-Negative Bacteria

(2012) Minho Lee et al.   PLoS One

Functional Implications of an Intermeshing Cogwheel-like Interaction between TolC and MacA in the Action of Macrolide-specific Efflux Pump MacAB-TolC

(2011) Yongbin Xu et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Funnel-like Hexameric Assembly of the Periplasmic Adapter Protein in the Tripartite Multidrug Efflux Pump in Gram-negative Bacteria

(2011) Yongbin Xu et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The periplasmic membrane proximal domain of MacA acts as a switch in stimulation of ATP hydrolysis by MacB transporter

(2011) Sita D. Modali et al.   MOLECULAR MICROBIOLOGY

Crystal structure of the CusBA heavy-metal efflux complex of Escherichia coli

(2011) Chih-Chia Su et al.   NATURE

Structures of sequential open states in a symmetrical opening transition of the TolC exit duct

(2011) Xue-Yuan Pei et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Elastic network model-based normal mode analysis reveals the conformational couplings in the tripartite AcrAB-TolC multidrug efflux complex

(2011) Beibei Wang et al.   PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS

The tip region of the MacA α-hairpin is important for the binding to TolC to the Escherichia coli MacAB–TolC pump

(2010) Yongbin Xu et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Structure of reconstituted bacterial membrane efflux pump by cryo-electron tomography

(2010) Sylvain Trépout et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES

Functional Relationships between the AcrA Hairpin Tip Region and the TolC Aperture Tip Region for the Formation of the Bacterial Tripartite Efflux Pump AcrAB-TolC

(2010) H.-M. Kim et al.   JOURNAL OF BACTERIOLOGY

Opening of the Outer Membrane Protein Channel in Tripartite Efflux Pumps Is Induced by Interaction with the Membrane Fusion Partner

(2010) Thamarai K. Janganan et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Structure of a fucose transporter in an outward-open conformation

(2010) Shangyu Dang et al.   NATURE

Crystal structures of the CusA efflux pump suggest methionine-mediated metal transport

(2010) Feng Long et al.   NATURE

The Bacterial Cell Envelope

(2010) T. J. Silhavy et al.   Cold Spring Harbor Perspectives in Biology

Crystallization and preliminary X-ray crystallographic analysis ofEscherichia coliCusB

(2009) Yongbin Xu et al.   Acta Crystallographica Section F-Structural Biology and Crystallization Communications

Association of Hemolytic Activity of Pseudomonas entomophila, a Versatile Soil Bacterium, with Cyclic Lipopeptide Production

(2009) I. Vallet-Gely et al.   APPLIED AND ENVIRONMENTAL MICROBIOLOGY

The multidrug resistance efflux complex, EmrAB from Escherichia coli forms a dimer in vitro

(2009) Mikio Tanabe et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Crystal Structure of the Periplasmic Region of MacB, a Noncanonic ABC Transporter,

(2009) Yongbin Xu et al.   BIOCHEMISTRY

Crystal Structure of the Multidrug Exporter MexB from Pseudomonas aeruginosa

(2009) Gaby Sennhauser et al.   JOURNAL OF MOLECULAR BIOLOGY

Crystal Structure of the Periplasmic Component of a Tripartite Macrolide-Specific Efflux Pump

(2009) Soohwan Yum et al.   JOURNAL OF MOLECULAR BIOLOGY

The assembled structure of a complete tripartite bacterial multidrug efflux pump

(2009) M. F. Symmons et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Kinetic control of TolC recruitment by multidrug efflux complexes

(2009) E. B. Tikhonova et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

MacAB Is Involved in the Secretion of Escherichia coli Heat-Stable Enterotoxin II

(2008) H. Yamanaka et al.   JOURNAL OF BACTERIOLOGY

MacB ABC Transporter Is a Dimer Whose ATPase Activity and Macrolide-binding Capacity Are Regulated by the Membrane Fusion Protein MacA

(2008) Hong Ting Lin et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Assembly and Channel Opening in a Bacterial Drug Efflux Machine

(2008) Vassiliy N. Bavro et al.   MOLECULAR CELL