期刊
COMPTES RENDUS BIOLOGIES
卷 334, 期 8-9, 页码 639-646出版社
ELSEVIER FRANCE-EDITIONS SCIENTIFIQUES MEDICALES ELSEVIER
DOI: 10.1016/j.crvi.2011.05.012
关键词
Tandem gene duplication; Chromosomal rearrangements; Evolution; Yeast
类别
资金
- CNRS [GDR 2354]
- ANR [ANR-05-BLAN-0331]
This short article presents an overview of tandem gene arrays (TGAs) in hemiascomycete yeasts. In silica and in vivo analyses are combined to address structural, functional and evolutionary aspects of these particular chromosomal structures. Genomic instability of TGAs is discussed. We conclude that TGAs are generally dynamic regions of the genome in that they are the seats of chromosomal rearrangement events. In addition, they are often breeding grounds of new genes for a rapid adaptation of cells to demands of the environment. (C) 2011 Academic des sciences. Published by Elsevier Masson SAS. All rights reserved.
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