期刊
COMPLEMENTARY THERAPIES IN MEDICINE
卷 21, 期 -, 页码 S54-S60出版社
CHURCHILL LIVINGSTONE
DOI: 10.1016/j.ctim.2011.08.002
关键词
Fever; Cytokines; Thermoregulation
This review describes how fever is generated as a regulated increase in body temperature. It results from an upward shift in the thermoregulatory set point, mediated by pyrogenic cytokines released from monocytes/macrophages in response to infection or trauma. Evidence will be presented that fever is part of an integrated host defense system, and that failure to generate a fever in response to infection is generally associated with a poorer prognosis. (c) 2011 Elsevier Ltd. All rights reserved.
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