Article
Immunology
Christa D. Jackson, Kinsey A. Hilliard, Charles R. Brown
Summary: The deficiency of 12/15-lipoxygenase (12/15-LO) exacerbates ankle swelling and arthritis severity in Lyme arthritis, suggesting that 12/15-LO lipid metabolites play a crucial role in resolving inflammatory arthritis. Therapeutic treatment with lipoxin A4 (LXA(4)) can alleviate joint edema and pain in Lyme arthritis patients.
FRONTIERS IN IMMUNOLOGY
(2023)
Article
Biochemistry & Molecular Biology
Sophie Roigas, Dagmar Heydeck, Hartmut Kuhn
Summary: Eicosanoids and related compounds are pleiotropic lipid mediators synthesized in mammals via different metabolic pathways. They have been implicated in inflammatory diseases and are targeted by anti-inflammatory drugs. While eicosanoid biosynthesis in mammals has been well explored, there is limited knowledge about it in other vertebrates, including bony fish. This study cloned and expressed putative ALOX15 orthologs from three bony fish species and characterized their catalytic properties. The results suggest that functional ALOX isoforms occur in bony fish, but they have different catalytic properties compared to mammalian enzymes. The possible roles of these ALOX isoforms in bony fish inflammation are discussed.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2022)
Article
Fisheries
Manuel Gesto, Lone Madsen, Nikolaj R. Andersen, Najlae El Kertaoui, Patrick Kestemont, Alfred Jokumsen, Ivar Lund
Summary: Different vegetable oils can be used as substitutes of fish oil in aquaculture feed, but they may cause deficiency in long chain polyunsaturated fatty acids in fish products. The welfare and health consequences of these alterations on fish are not well known.
Article
Medicine, Research & Experimental
Mehrdad Zarei, Pooja Acharya, Ramaprasad Ravichandra Talahalli
Summary: The study showed that repeatedly using deep-fried oils may cause hepatic dysfunction, while adding ginger or turmeric during heating can prevent the hepatic inflammatory response.
Article
Biochemistry & Molecular Biology
Chenyang Lu, Ju Chen, Congmin Yi, Jiaojiao Han, Qiuyue Shi, Jingjing Li, Bing Liu, Jun Zhou, Xiurong Su
Summary: The study revealed that tuna oil has beneficial effects on collagen-induced arthritis in mice by reducing arthritis severity, improving joint bone erosion and systemic inflammation, balancing bone remodeling through signaling pathways, and repairing the impaired intestinal epithelial barrier and modulating gut microbiota.
Article
Nutrition & Dietetics
Elis C. S. Fatel, Flavia T. Rosa, Daniela F. Alfieri, Tamires Flauzino, Bruna M. Scavuzzi, Marcell A. B. Lozovoy, Tatiana M. V. Iriyoda, Andrea N. C. Simao, Isaias Dichi
Summary: The study indicates that consuming cranberry juice in conjunction with fish oil supplementation can reduce disease activity and inflammatory markers in people with rheumatoid arthritis.
Article
Nutrition & Dietetics
Mengyi Liu, Ziliang Ye, Sisi Yang, Yanjun Zhang, Qimeng Wu, Chun Zhou, Panpan He, Yuanyuan Zhang, Fanfan Hou, Xianhui Qin
Summary: This study aimed to explore the relationship between habitual fish oil use and the risk of chronic kidney diseases (CKD). A total of 408,023 participants without prior CKD were enrolled from the UK Biobank. Fish oil use and dietary intakes were assessed through questionnaires. The study found that habitual fish oil use was associated with a lower hazard of CKD, and there were consistent inverse relationships between fish consumption and circulating omega-3 PUFA concentration with incident CKD.
Review
Microbiology
Susana Ruiz Mendoza, Daniel Zamith-Miranda, Tamas Takacs, Attila Gacser, Joshua D. Nosanchuk, Allan J. Guimaraes
Summary: The prevalence of fungal infections has been increasing in immunocompromised patients, with arachidonic acid metabolites playing important roles in regulating immune function. Fungal-produced prostaglandins have immunomodulatory functions similar to mammalian counterparts, potentially serving as new targets for combating various fungal infections.
Article
Biochemistry & Molecular Biology
Kannan Sridharan, Ali Mohamed Qader, Mustafa Hammad, Anfal Jassim, Diab Eltayeb Diab, Betsy Abraham, Hasan M. S. N. Hasan, Sheikh Abdul Azeez Pasha, Shamik Shah
Summary: This study investigated the prevalence of SNPs related to paracetamol metabolism in critically ill patients and those with chronic kidney disease. The results showed that SNPs led to alterations in metabolite concentrations and ratios, and patients with renal dysfunction had higher paracetamol concentrations.
Article
Biochemistry & Molecular Biology
Sheethal Sreevallabhan, Ratheesh Mohanan, Svenia P. Jose, Sandya Sukumaran, Tariq Jagmag, Jayesh Tilwani, Anuradha Kulkarni
Summary: The study shows that Phoscoliv significantly enhances antioxidant status, inhibits oxidative stress reaction, reduces lipid peroxidation, decreases the release of pro-inflammatory cytokines, and helps maintain the normal structure of the liver.
JOURNAL OF FOOD BIOCHEMISTRY
(2021)
Article
Biochemistry & Molecular Biology
Helen M. M. Lindqvist, Anna Winkvist, Inger Gjertsson, Philip C. C. Calder, Aaron M. M. Armando, Oswald Quehenberger, Roxana Coras, Monica Guma
Summary: A study on patients with rheumatoid arthritis found that consuming blue mussels, which are rich in n-3 fatty acids, led to significant changes in certain oxylipin levels, but did not have a noticeable impact on inflammation. Further research is needed to investigate the relationship between n-3 fatty acid intake, blood oxylipins, and inflammation.
Article
Agriculture, Multidisciplinary
Krzysztof Kawecki, Ryszard Rezler, Hanna M. Baranowska, Jerzy Stangierski
Summary: The study found that the sample with microcapsules had slightly higher total protein content. The addition of encapsulated oil reduced the pH and water activity value in the meat batter compared to the control sample. There was an inverse correlation between the dynamic viscosity of the batters and the spin-spin relaxation times. The modulus of elasticity in all systems exhibited three areas of change in temperature.
JOURNAL OF THE SCIENCE OF FOOD AND AGRICULTURE
(2021)
Article
Nutrition & Dietetics
William Yakah, David Ramiro-Cortijo, Pratibha Singh, Joanne Brown, Barbara Stoll, Madhulika Kulkarni, Berthe C. Oosterloo, Doug Burrin, Krishna Rao Maddipati, Raina N. Fichorova, Steven D. Freedman, Camilia R. Martin
Summary: Comparing the effects of different lipid emulsions on preterm pigs, it was found that soybean oil enhances the ability of the host to respond acutely to an external stimulus, while fish-oil containing emulsions increase DHA levels, exacerbate AA deficiency, and limit initial inflammatory responses induced by LPS in preterm pigs.
Article
Environmental Sciences
Elizabeth Allmon, Grace Carter, Robert Griffitt, Maria S. Sepulveda
Summary: Research on the cardiotoxic effects of oil on fish has mainly focused on rapidly developing pelagic species, with little emphasis on estuarine species with longer embryological periods. This study fills a knowledge gap by exposing sheepshead minnow embryos to oil and measuring cardiac responses through identifying cardiotoxic phenotypes and calculating cardiac output, finding significant increases in pericardial edema and reduced cardiac output at both oil doses. The methods described in this study allow for more physiologically relevant measures of cardiac performance in early life stages.
Article
Pharmacology & Pharmacy
Sadaf Naeem, Liaquat Ali, Rahila Ikram, Saira Saeed Khan, Huma Shareef, Yousra Shafiq, Nausheen Alam, Anum Adil
Summary: The study found that sesame oil, fish oil, and a combination of both showed positive effects in antioxidant and analgesic properties, with the SO+FO combination showing significant results in both aspects.
PAKISTAN JOURNAL OF PHARMACEUTICAL SCIENCES
(2021)
Article
Health Care Sciences & Services
Jodie B. Hillen, Agnes Vitry, Gillian E. Caughey
AUSTRALIAN JOURNAL OF PRIMARY HEALTH
(2016)
Article
Endocrinology & Metabolism
G. E. Caughey, J. D. Barratt, S. Shakib, A. Kemp-Casey, E. E. Roughead
Article
Medicine, General & Internal
G. E. Caughey, A. I. Vitry, E. N. Ramsay, A. L. Gilbert, S. Shakib, P. Ryan, A. Esterman, R. A. McDermott, E. E. Roughead
INTERNAL MEDICINE JOURNAL
(2016)
Editorial Material
Medicine, General & Internal
Nicole L. Pratt, Emmae N. Ramsay, Gillian E. Caughey, Sepehr Shakib, Elizabeth E. Roughead
MEDICAL JOURNAL OF AUSTRALIA
(2016)
Article
Multidisciplinary Sciences
Sepehr Shakib, Benjamin K. Dundon, John Maddison, Josephine Thomas, Melinda Stanners, Gillian E. Caughey, Robyn A. Clark
Article
Medicine, General & Internal
Joshua M. Inglis, Gillian E. Caughey, William Smith, Sepehr Shakib
INTERNAL MEDICINE JOURNAL
(2017)
Article
Medicine, General & Internal
Gillian E. Caughey, Nicole L. Pratt, John D. Barratt, Sepehr Shakib, Anna R. Kemp-Casey, Elizabeth E. Roughead
MEDICAL JOURNAL OF AUSTRALIA
(2017)
Article
Medicine, General & Internal
Gillian E. Caughey, Kirsty Tait, Agnes I. Vitry, Sepehr Shakib
PATIENT PREFERENCE AND ADHERENCE
(2017)
Review
Geriatrics & Gerontology
Nashwa Masnoon, Sepehr Shakib, Lisa Kalisch-Ellett, Gillian E. Caughey
Review
Geriatrics & Gerontology
Nashwa Masnoon, Sepehr Shakib, Lisa Kalisch-Ellett, Gillian E. Caughey
Article
Orthopedics
M. C. S. Inacio, K. Cashman, N. L. Pratt, M. H. Gillam, G. Caughey, S. E. Graves, E. E. Roughead
OSTEOARTHRITIS AND CARTILAGE
(2018)
Article
Pharmacology & Pharmacy
Nicholas Farinola, Gillian E. Caughey, J. Simon Bell, Sally Johns, Milka Hauta-aho, Sepehr Shakib
THERAPEUTIC ADVANCES IN DRUG SAFETY
(2018)
Article
Pharmacology & Pharmacy
Gillian E. Caughey, Lisa M. Kalisch Ellett, John D. Barratt, Sepehr Shakib
THERAPEUTIC ADVANCES IN DRUG SAFETY
(2017)
Article
Geriatrics & Gerontology
Jodie Belinda Hillen, Agnes Vitry, Gillian E. Caughey
AUSTRALASIAN JOURNAL ON AGEING
(2017)
Article
Pharmacology & Pharmacy
Gao-Jing Ong, Amy Page, Gillian Caughey, Sally Johns, Emily Reeve, Sepehr Shakib
PHARMACOLOGY RESEARCH & PERSPECTIVES
(2017)