Article
Physiology
C. Andre, S. V. Duy, S. Sauve, F. Gagne
Summary: The neuroendocrine effects of municipal discharge and rainfall overflow on mussels were compared in this study. Municipal effluent led to feminizing effects and inflammation, while rainfall overflow specifically affected the Vtg protein levels and reproductive function in females.
FRONTIERS IN PHYSIOLOGY
(2023)
Article
Environmental Sciences
Sylvie Poirier Larabie, Martin Jutras, Gregoire Leclair, Isabelle St-Jean, Christine Kleinert, Francois Gagne, Christian Gagnon
Summary: Aquatic organisms are exposed to emerging contaminants from urban wastewater treatment plants. Pharmaceuticals, including anticancer drugs, are not treated by these plants, posing potential risks to aquatic organisms. The study developed a specific and sensitive LC-MS/MS method for quantifying methotrexate uptake in mussels and revealed low uptake potential of the drug. The method could be useful for examining tissue levels in organisms exposed to urban pollution.
ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH
(2022)
Article
Marine & Freshwater Biology
Marcus J. Forbes-Green, Helene Cyr
Summary: Native freshwater mussels are endangered globally, emphasizing the importance of studying them for conservation efforts. This study examines the impact of physical disturbances and sedimentary habitat on the growth of Elliptio complanata mussels. It finds that sediments provide a refuge for juvenile and young adult mussels, while disturbance events do not negatively affect their growth.
Article
Biochemistry & Molecular Biology
Christine Kleinert, Sylvie Poirier-Larabie, Christian Gagnon, Chantale Andre, Francois Gagne
Summary: The study revealed that cytostatic drugs released in municipal effluents have sublethal toxicity to freshwater mussels, with 5-fluorouracil showing a wider range of effects compared to methotrexate.
COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY C-TOXICOLOGY & PHARMACOLOGY
(2021)
Article
Ecology
David L. Strayer, Stephen K. Hamilton, Heather M. Malcom
Summary: The study found that the shell thickness of Elliptio complanata in the Hudson River increased significantly over the study period, possibly due to changes in water chemistry and predation pressure. Similar changes in shell thickness may be occurring in freshwater environments worldwide, affecting ecological interactions and ecosystem functioning.
FRESHWATER BIOLOGY
(2021)
Article
Environmental Sciences
Priscila Romana da Silva, Ann H. Mounteer, Laercio dos Anjos Benjamin, Edinael Rodrigues de Almeida, Flavia Barros Vitorino, Gemima Santos Arcanjo, Vinicius Rodrigues dos Santos Petersen
Summary: The study indicated that while the upflow anaerobic sludge blanket (UASB) reactor can meet Brazilian legal limits for BOD and COD removals, it is unable to fully remove the toxicity of sewage, which remains highly toxic to Danio rerio and Ceriodaphnia dubia.
Article
Environmental Sciences
Patrice Turcotte, Shirley Anne Smyth, Francois Gagne, Christian Gagnon
Summary: This study investigated the fate of lanthanides in different wastewater treatment processes, and differentiated the origin of gadolinium (Gd) between medical application and geological background using a normalization approach. The results showed that the removal efficiency of lanthanides decreased with their atomic number, and the process using alum as a flocculating agent had the highest removal efficiency.
Article
Environmental Sciences
Marc-Antoine Vaudreuil, Sung Vo Duy, Gabriel Munoz, Sebastien Sauve
Summary: A method for quantification of multi-class pharmaceuticals in wastewaters from hospitals was developed and validated in this study. The results showed high concentrations of pharmaceuticals in hospital wastewaters and their better affinity to suspended solids. These findings provide arguments for at source treatment of these specific effluents before their introduction into urban wastewater systems.
SCIENCE OF THE TOTAL ENVIRONMENT
(2022)
Article
Environmental Sciences
Karan Parekh, Vicki L. Marlatt
Summary: This study investigated the effects of Metro Vancouver's wastewater treatment plant effluents on hepatic gene expression in English sole. The results showed differences in xenobiotic defense, thyroid function, lipid and glucose metabolism, protein synthesis, and reproduction at impacted sites. Male English sole exhibited widespread exposure to estrogenic contaminants, while the induction of hepatic CYP1A was observed due to influx of certain hydrocarbons from industrial contributors.
Article
Environmental Sciences
Elise N. Millar, Michael G. Surette, Karen A. Kidd
Summary: Municipal wastewater treatment plants contain contaminants that may impact the composition of beneficial bacterial communities associated with aquatic organisms. This study found that the microbiomes of invertebrates collected downstream of WWTPs differed from those collected upstream, which could have implications for host health and the transport of WWTP-derived bacteria in aquatic ecosystems.
SCIENCE OF THE TOTAL ENVIRONMENT
(2022)
Article
Engineering, Environmental
Urs Jans, Carsten Prasse, Urs von Gunten
Summary: The Fe-TAML/H2O2 system is effective in degrading electron-rich phenolic compounds and polyaromatic ethers in wastewater, but shows slower oxidation rates for other types of compounds. Trichlorophenol is readily oxidized by the system, and iodide is oxidized to hypoiodous acid, accelerating H2O2 consumption.
ENVIRONMENTAL SCIENCE & TECHNOLOGY
(2021)
Article
Environmental Sciences
Cihang Yan, Jiayin Liu, Zhiyu Wei, Jie Chen, Yutong Ji, Lu Fan
Summary: This study investigated the bioavailability of organic nitrogen contaminants in wastewater treatment plant effluents through bioassays, using 4 kinetic models to describe the mineralization process. The findings showed that the Gamma model was the best fit for describing the variability in bioavailability and degradation rates of organic nitrogen in wastewater effluent.
JOURNAL OF ENVIRONMENTAL MANAGEMENT
(2022)
Article
Microbiology
Poulami Sarkar, Murad Ghanim
Summary: This study reveals the interactions between the carrot psyllid and CLso, identifying vitellogenin as a key player in the immune response against CLso. The expression of vitellogenin influences autophagy and the abundance of CLso, ultimately affecting the mortality of the psyllid vector.
MICROBIOLOGY SPECTRUM
(2022)
Article
Environmental Sciences
Tiza Spit, Jan Peter van der Hoek, Coen de Jong, Doris van Halem, Merle de Kreuk, Bruno Bicudo Perez
Summary: This study investigated the removal of organic micropollutants (OMPs) and antibiotic resistance (AR) using ozone, coagulation, and granular activated carbon (GAC) filtration in wastewater treatment plants. The results showed that ozone and coagulation effectively removed both antibiotic-sensitive bacteria (ASB) and antibiotic-resistant bacteria (ARB), although higher doses were required. GAC filters posed a risk of enhancing ARB, particularly in filters with a matured biology.
FRONTIERS IN ENVIRONMENTAL SCIENCE
(2022)
Article
Biochemistry & Molecular Biology
S. Miyazaki, H. Shimoji, R. Suzuki, I. Chinushi, H. Takayanagi, H. Yaguchi, T. Miura, K. Maekawa
Summary: In eusocial insect colonies, non-reproductive workers shift tasks based on age and colony demography, with the vitellogenin gene playing regulatory roles. In primitive ants like Diacamma sp., the expressions of CVg and Vg-like A in the brain are associated with nursing tasks, suggesting sub-functionalization of Vg functions in derived ant lineages.
INSECT MOLECULAR BIOLOGY
(2021)
Article
Biochemistry & Molecular Biology
N. Hebert, F. Gagne, P. Cejka, B. Bouchard, R. Hausler, D. G. Cyr, C. Blaise, M. Fournier
COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY C-TOXICOLOGY & PHARMACOLOGY
(2008)
Article
Biochemistry & Molecular Biology
F. Gagne, B. Bouchard, C. Andre, E. Farcy, M. Fournier
COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY C-TOXICOLOGY & PHARMACOLOGY
(2011)
Article
Public, Environmental & Occupational Health
J. Lassausaie, A. Bret, X. Bouapao, V. Chanthavong, J. Castonguay-Vanier, F. Quet, S. K. Mikota, C. Theoret, Y. Buisson, B. Bouchard
EPIDEMIOLOGY AND INFECTION
(2015)
Article
Infectious Diseases
C. Thammavong, P. Paboriboune, B. Bouchard, A. Harimanana, F-X. Babin, P. Phimmasone, J-L. Berland, Y. Buisson
INTERNATIONAL JOURNAL OF TUBERCULOSIS AND LUNG DISEASE
(2011)
Article
Veterinary Sciences
Bertrand Bouchard, Bounmy Xaymountry, Nikorn Thongtip, Preeda Lertwatcharasarakul, Worawidh Wajjwalku
JOURNAL OF ZOO AND WILDLIFE MEDICINE
(2014)
Article
Multidisciplinary Sciences
Bertrand Bouchard, Jean-Yves Barnagaud, Marion Poupard, Herve Glotin, Pauline Gauffier, Sara Torres Ortiz, Thomas J. Lisney, Sylvie Campagna, Marianne Rasmussen, Aurelie Celerier
Article
Agriculture, Dairy & Animal Science
Bertrand Bouchard, Thomas J. Lisney, Sylvie Campagna, Aurelie Celerier
APPLIED ANIMAL BEHAVIOUR SCIENCE
(2017)
Article
Biochemistry & Molecular Biology
Gabriela Maressa Machado Baesso, Amanda Vitoria Venancio, Livia Costa Varela Barca, Pepita Fernanda Peppi, Caique Aparecido Faria, Joao Pedro Cosmo Machado, Luiz David Solis Murgas, Alvaro Jose de Almeida Bicudo, Eduardo Mauricio Mendes de Lima, Andre Rodrigues da Cunha Barreto-Vianna
Summary: This study evaluated the effects of eugenol, menthol, and lidocaine as anesthetics on glucose levels and recovery times in zebrafish. The results showed that eugenol and menthol did not affect glucose levels, while lidocaine caused non-concentration-dependent hyperglycemia. Recovery times were similar for eugenol and menthol, but concentration-dependent for lidocaine. Eugenol and menthol were deemed safe and satisfactory for glucose analysis in zebrafish research, while lidocaine could introduce biases and safety concerns. Researchers should carefully consider the selection of anesthetics for reliable results in zebrafish assessments.
COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY C-TOXICOLOGY & PHARMACOLOGY
(2024)
Article
Biochemistry & Molecular Biology
Xiaoxue Li, Tangsong Feng, Weiqun Lu
Summary: This study reveals that exposure to VPA induces ASD-like phenotypes and behaviors, including gene transcription changes, social interaction deficit, decreased aggression, increased anxiety behavior, and elevated cortisol levels. The aggression behavior assay is a better predictor of neurotoxicology behavior of VPA.
COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY C-TOXICOLOGY & PHARMACOLOGY
(2024)
Article
Biochemistry & Molecular Biology
Garam An, Junho Park, Whasun Lim, Gwonhwa Song
Summary: In this study, we investigated the hepatotoxicity and mechanism of action of pyridaben using zebrafish and ZFL cells. Pyridaben caused liver size reduction and apoptosis, and these effects were associated with uncontrolled intracellular calcium flow and downregulation of the PI3K/Akt signaling cascade.
COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY C-TOXICOLOGY & PHARMACOLOGY
(2024)
Article
Biochemistry & Molecular Biology
Md Alamgir Kabir, Md. Golam Rabbane, Marco R. Hernandez, Md Aftab Ali Shaikh, Mohammad Moniruzzaman, Xuexiu Chang
Summary: This study investigated the toxicity of high concentrations of cadmium (Cd) on intestinal immunity and microbial diversity in common carp. The results showed that high Cd concentration caused intestinal inflammation, immunosuppression, and changes in the gut microbiome, leading to detrimental effects on the intestinal homeostasis and health status of the fish.
COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY C-TOXICOLOGY & PHARMACOLOGY
(2024)
Article
Biochemistry & Molecular Biology
Anuradha Batabyal, Veronica Rivi, Cristina Benatti, Johanna M. C. Blom, Fabio Tascedda, Ken Lukowiak
Summary: This study found that exposure to heat shock stressors and bacterial lipopolysaccharide can induce the Garcia effect in pond snails. Additionally, aspirin can prevent the formation of the Garcia effect. However, unexpectedly, exposure to crushed aspirin and heat shock stressors together leads to long-lasting feeding suppression and molecular changes in the snails' serotoninergic system and neuroplasticity genes.
COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY C-TOXICOLOGY & PHARMACOLOGY
(2024)
Article
Biochemistry & Molecular Biology
Li-Yih Lin, Chieh-An Cheng, Sian-Tai Liu, Jiun-Lin Horng
Summary: This study reveals that ammonia exposure impairs ion regulation in zebrafish embryos by inducing oxidative stress, mitochondrial dysfunction, and cell death. The findings suggest that ammonia is toxic to aquatic animals and can lead to the death of embryos.
COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY C-TOXICOLOGY & PHARMACOLOGY
(2024)
Article
Biochemistry & Molecular Biology
Antonio Durate Pagano, Natieli Machado Goncalves, William Borges Domingues, Tony Leandro Rezende da Silveira, Mateus Tavares Kutter, Antonio Sergio Varela Jr, Carine Dahl Corcini, Mariana Cavalcanti Nascimento, Luana Ferreira Viana dos Reis, Patricia Gomes Costa, Adalto Bianchini, Matheus Vieira Volcan, Mariana Harter Remia, Vinicius Farias Campos
Summary: This study analyzed the toxic effects of Roundup Transorb (R) on the endangered Neotropical annual killifish Austrolebias charrua by evaluating molecular and biochemical biomarkers. The findings showed that exposure to Roundup significantly increased the production of reactive oxygen species, lipid peroxidation, and DNA damage in the fish's blood cells. It also decreased membrane fluidity. Gene expression analysis revealed alterations in genes associated with oxidative stress and antioxidant defense. This study provides new insights into adaptive mechanisms of A. charrua in response to Roundup, and it has important implications for environmental monitoring and aquatic toxicology assessment.
COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY C-TOXICOLOGY & PHARMACOLOGY
(2024)
Article
Biochemistry & Molecular Biology
Xiaochan Gao, Hongtao Ren, Yong Huang, Yimin Li, Jiaqi Shen
Summary: The influence of multi-walled carbon nanotubes (MWCNTs) on the toxicity of zinc oxide nanoparticles (ZnONPs) in the intestine of common carp was investigated. The study found that the concentration and concentration ratio of the mixture played a role in the toxicity of ZnONPs. The presence of MWCNTs significantly decreased intercellular zinc accumulation and altered the microbial community diversity and composition of the gut microbiota.
COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY C-TOXICOLOGY & PHARMACOLOGY
(2024)
Article
Biochemistry & Molecular Biology
Guangchao Yang, Qian Yang, Trust Beta, Qin Liu, Zhenzhu Zhu, Fei Shen
Summary: The study found that black garlic MLDs have alleviative effects on ZEN-induced toxicity, and exert their effects through antioxidative, anti-apoptotic, and inhibitory mechanisms on ZEN absorption.
COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY C-TOXICOLOGY & PHARMACOLOGY
(2024)
Article
Biochemistry & Molecular Biology
Tuul Sepp, Ciara Baines, Randel Kreitsberg, Joern Peter Scharsack, Pedro Nogueira, Thomas Lang, Jerome Fort, Elin Sild, John T. Clarke, Arvo Tuvikene, Richard Meitern
Summary: Environmental factors can cause cancer in both wild animals and humans. The use of polluted habitats provides opportunities to study cancer defense mechanisms, which can be influenced by genetic variation and natural selection. Flatfish species, specifically flounders, show higher resistance to pollution-induced cancer compared to dabs, with elevated pollutant metabolism and stronger tumor suppression mechanisms in their liver tissue. This suggests a potential hormetic upregulation of tumor suppression or stronger natural selection pressure for cancer resistance in flounders. Wild species offer valuable insights into understanding the nature and evolution of natural cancer defense mechanisms.
COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY C-TOXICOLOGY & PHARMACOLOGY
(2024)
Article
Biochemistry & Molecular Biology
Regan A. Moss, Kaitlyn M. Murphy, Steven T. Gardner, Madison M. Watkins, John W. Finger Finger Jr, Meghan D. Kelley, Ruth M. Elsey, Daniel A. Warner, Mary T. Mendonca
Summary: The study explored the impact of environmentally relevant concentrations of E2 on the immune system and hormone levels of hatchling American alligators. Results showed that exposure to environmental estrogen can alter plasma hormone concentrations but have little to no impact on morphology and immune responses.
COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY C-TOXICOLOGY & PHARMACOLOGY
(2024)
Article
Biochemistry & Molecular Biology
Ye Liang, Zihao Li, Jing Yuan, Yiwen Zhou, Meng Li, Haifeng Gu
Summary: This study investigated the toxicity mechanism of homo-YTX and NH3-N on the survival of abalone. The results showed that homo-YTX and NH3-N enhanced oxidative stress and lipid peroxidation reactions, inhibited energy supply, disrupted metabolic and immune physiological functions, and activated apoptosis in the gills of abalone.
COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY C-TOXICOLOGY & PHARMACOLOGY
(2024)