Article
Agriculture, Dairy & Animal Science
Yiming Li, Ji De, Qichen Jiang, Ying Yang, Wenyue Xu, Xinglin Du, Yunlong Zhao
Summary: Ammonia nitrogen exposure can cause damage to the hepatopancreas structure and disturb lipid metabolism of juvenile shrimp. Hybrid offspring populations have stronger resistance to ammonia nitrogen stress compared to the broodstock populations.
Article
Agronomy
Alessandra Janaina Becker, Luciano Jensen Vaz, Luciano de Oliveira Garcia, Wilson Wasielesky Jr, Berta Maria Heinzmann, Bernardo Baldisserotto
Summary: The study evaluated the anesthetic efficacy of essential oils for two shrimp species, with induction times decreasing with concentration increase, and some mortality observed at the highest concentration of EOOG. Shrimp exposed to EOC and EOO had significantly shorter induction times, while those exposed to EOO had significantly longer recovery times. Overall, the action of essential oils differed significantly between the two shrimp species.
Article
Engineering, Environmental
Yiguo Lei, Zhixiang Yuan, Qingtian Zeng, Boquan Wan, Jianyong Liu, Wei Wang
Summary: Despite its versatility, the involvement of RNA m6A methylation in shrimp's response to ammonia nitrogen toxicity is not well understood. This study characterized the dynamic RNA m6A methylation landscapes induced by toxic ammonia exposure in the Pacific whiteleg shrimp. The global m6A methylation level decreased significantly after ammonia exposure, and many m6A methyltransferases and binding proteins were repressed. The differentially methylated genes were enriched in pathways related to metabolism, immune defense, and apoptotic signaling.
JOURNAL OF HAZARDOUS MATERIALS
(2023)
Article
Environmental Sciences
Zhi Liang, Tianci Chen, Furong Yang, Shuhong Li, Shuang Zhang, Hui Guo
Summary: This study investigated the effects of different concentrations of zinc on the growth performance, morphological changes, physiological changes, and gene expression in white shrimp hepatopancreas. The results showed that high concentrations of zinc significantly reduced survival rate and growth performance, and caused structural damage and zinc accumulation in the hepatopancreas. Zinc exposure led to decreased activities of digestive enzymes and total antioxidant capacity, and increased production of reactive oxygen species and malondialdehyde. Transcriptome analysis revealed many differentially expressed genes, and qRT-PCR validation confirmed the accuracy of the results. The study demonstrated that zinc exposure caused severe histopathological changes and altered immune, antioxidant, and detoxifying responses by regulating gene expressions.
Article
Fisheries
Huan Chen, Zuhao Zhang, Zhihong Wu, Ruibing Peng, Xiamin Jiang, Qingxi Han, Maowang Jiang
Summary: The goal of this study was to explore the detoxification metabolic pathway and regulatory mechanism of the cuttlefish under ammonia nitrogen stress. The study found that the cuttlefish can detoxify ammonia nitrogen into urea through urea metabolism and utilize amino acid metabolic pathways to reduce ammonia nitrogen content in the body. However, these pathways are inhibited under high ammonia nitrogen stress.
Article
Environmental Sciences
Mingming Zhao, Zhihong Zheng, Chuanqi Wang, Defu Yao, Zhongyang Lin, Yongzhen Zhao, Xiuli Chen, Shengkang Li, Jude Juventus Aweya, Yueling Zhang
Summary: Agricultural and anthropogenic activities release high levels of ammonia into aquatic ecosystems, which severely affect aquatic organisms. This study found that shrimp can survive under high ammonia stress conditions, and a peptide called HMCs27 enhances the antioxidant system and the tricarboxylic acid cycle to attenuate ammonia toxicity.
SCIENCE OF THE TOTAL ENVIRONMENT
(2023)
Article
Environmental Sciences
Xianyun Ren, Shaoting Jia, Baoquan Gao, Qiansen Zhou, Yao Xu, Ping Liu, Jian Li
Summary: This study analyzed the effects of ammonia on the proteome and metabolome of the ornate spiny lobster. Significant changes were observed in proteins and metabolites related to immune response, biotransformation, metabolism, and antioxidant system. The utilization of the urea cycle to reduce ammonia content was also observed. These findings provide insights into the response mechanisms of the lobster to ammonia stress and can contribute to the development of efficient aquaculture methods.
SCIENCE OF THE TOTAL ENVIRONMENT
(2022)
Article
Fisheries
Yiming Li, Wenyue Xu, Bihong Zhu, Qichen Jiang, Yucong Ye, Yunlong Zhao
Summary: Ammonia nitrogen is a significant source of water pollution that severely restricts the development of aquaculture. This study found that the hybrid population had a greater detoxifying capacity and stress resistance ability compared to the parental population under the same concentration of ammonia nitrogen stress.
AQUACULTURE RESEARCH
(2022)
Article
Environmental Sciences
Hannah M. Lowes, Alyssa M. Weinrauch, Ian A. Bouyoucos, Robert A. Grif, Daniels Kononovs, Daniel S. Alessi, Tamzin A. Blewett
Summary: Intertidal animals are exposed to tidal emersion and copper toxicity, but little is known about the interactions of these two stressors. This study examined the effects of copper exposure and tidal emersion on the sea cucumber Cucumaria miniata, finding that copper accumulated in the respiratory tree and had negative effects on aerobic metabolism. Emersion affected copper accumulation and increased oxygen uptake and ammonia excretion upon re-immersion.
SCIENCE OF THE TOTAL ENVIRONMENT
(2023)
Article
Environmental Sciences
Yunshi Liang, Yi Wu, Jianping Li, Ruibing Peng, Maowang Jiang, Xiamin Jiang, Siqing Chen, Jianyuan Lin
Summary: This study examined the effect of gamma-aminobutyric acid (GABA) as a supplement on the ammonia stress resistance of S. pharaonis. The results showed that the application of GABA significantly alleviated the adverse effects of ammonia poisoning, with the best effect observed at a dosage of 80-100 mg/kg.
ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY
(2022)
Article
Environmental Sciences
Daojie Li, Long Shen, Di Zhang, Xiaotong Wang, Qiankun Wang, Wenhao Qin, Yun Gao, Xiaoping Li
Summary: Ammonia, a common toxic gas and one of the main causes of haze, can directly affect human and animal health by inducing apoptosis and DNA oxidative damage in the lungs. It also leads to oxidative stress and inflammatory response. These findings provide new insights into the toxicity of ammonia to workers in livestock farms and chemical fertilizer plants.
JOURNAL OF ENVIRONMENTAL SCIENCES
(2023)
Article
Engineering, Environmental
Guorui Xing, Jiaqi Lu, Lixia Xuan, Jiong Chen, Jinbo Xiong
Summary: Antibiotic pollution poses serious threats to public health and ecological processes. However, systematic research on the interactive effects of increasing nutrient and antibiotic pollution on prokaryotic communities is lacking. This study explored the complex interactions between bacteria, archaea, and various factors and found that the sediment prokaryotic assembly is primarily influenced by sediment antibiotic pollution, ammonia, phosphate, and redox potential. The study also revealed significant tipping points and bio-indicators for regime shift and quantitative diagnosis of antibiotic pollution.
JOURNAL OF HAZARDOUS MATERIALS
(2022)
Article
Environmental Sciences
Chengsong Zhang, Yue Jin, Yang Yu, Jianhai Xiang, Fuhua Li
Summary: The study exposed adult Palaemonid shrimp Palaemon macrodactylus to gradient concentrations of Cadmium (Cd) and found that Cd caused acute toxic effects in this species, including bioaccumulation, induced oxidative stress, and changed energy metabolism.
ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY
(2021)
Article
Fisheries
Amit Kumar Sinha, Noah Limbaugh, Nilima Renukdas, West M. Bishop, Nicholas Romano
Summary: The aim of this study was to assess the effect of increased water hardness on channel catfish, and it was found that while increased water hardness negatively affected the growth performance of the fish, it also alleviated the inhibitory effects of high ammonia exposure on growth. High water hardness may achieve this by protecting the gills and regulating ammonia excretion. However, increased hardness may not be effective in alleviating salinity stress.
Article
Engineering, Environmental
Bettie Cormier, Florane Le Bihanic, Mathieu Cabar, Jean-Claude Crebassa, Melanie Blanc, Maria Larsson, Florian Dubocq, Leo Yeung, Christelle Clerandeau, Steffen H. Keiter, Jerome Cachot, Marie-Laure Begout, Xavier Cousin
Summary: The toxicity of polyethylene (PE) and polyvinyl chloride (PVC) microplastics (MPs) was evaluated in zebrafish and marine medaka over 4 months. The exposure through diet resulted in a significant decrease in growth and reproductive output, with PVC showing more reprotoxic effects compared to PE. The presence of sorbed chemicals in MPs may lead to serious ecological disruptions.
JOURNAL OF HAZARDOUS MATERIALS
(2021)
Article
Environmental Sciences
Bruna Duarte Pereira Righi, Lais Donini Abujamara, Indianara Fernanda Barcarolli, Marianna Basso Jorge, Yuri Dornelles Zebral, Patricia Gomes Costa, Claudia Bueno dos Reis Martinez, Adalto Bianchini
Summary: The response of biomarkers to chemical contamination in crabs from two tropical estuaries in Maranhao State, northeastern Brazil showed significant spatial, seasonal, and annual variability. The study found higher Zn concentration in crabs from Sao Jose Bay and higher Cd concentration with oxidative damage in crabs from Sao Marcos Bay. Levels of lipid peroxidation in crab hepatopancreas were identified as the most reliable biomarker to distinguish the two bays.
Article
Environmental Sciences
Juliana Lemos Dal Pizzol, Joseane Aparecida Marques, Juliana da Silva Fonseca, Patricia Gomes Costa, Adalto Bianchini
Summary: This study evaluated the influence of metal accumulation on the oxidative status and enzyme activity in coral and hydrocoral species in Abrolhos Reef Banks. The results indicated that the hydrocoral M. alcicornis was more affected by metals than the coral M. harttii, and CA activity can serve as a complementary biomarker for assessing the physiological impacts of environmental metal contamination in reefs. The findings also provide reference data for monitoring reef health impacted by a relevant dam rupture.
Article
Marine & Freshwater Biology
Amanda da Silveira Guerreiro, Bruna de Vargas Guterres, Patricia Gomes Costa, Adalto Bianchini, Silvia Silva da Costa Botelho, Juliana Zomer Sandrini
Summary: This study analyzed the effects of diesel water accommodated-fraction (WAF) on the behavioral and biochemical responses of Perna perna mussels. The results demonstrate that WAF exposure alters both behavior and biochemical biomarkers.
AQUATIC TOXICOLOGY
(2022)
Article
Environmental Sciences
Anieli C. Maraschi, Joseane A. Marques, Simone R. Costa, Carlos E. D. Vieira, Patricia G. Costa, Camila de M. G. Martins, Juliana Z. Sandrini, Adalto Bianchini, Marta M. Souza
Summary: The disruption of the Funda & SIM;o dam resulted in the release of a large amount of mine tailings into the Doce River and eventually the ocean, posing challenges for the local biota. Analysis of shrimp samples from different sectors during dry and wet seasons showed seasonal and local effects on the bioaccumulation profile and biomarker response. The study suggests a higher bioavailability of metals during dry season, particularly for Cd, Cr, Cu, and Mn, and a higher Fe bioavailability in estuarine sectors during wet season. Native marine shrimp species proved to be effective indicators of sediment quality and sensitive to water contamination by metals. The findings highlight the importance of continuous monitoring in the estuarine region to understand the long-term effects of metal bioavailability, especially Fe, on the local biota.
ENVIRONMENTAL POLLUTION
(2022)
Article
Environmental Sciences
Vinicius Dias Borges, Yuri Dornelles Zebral, Patricia Gomes Costa, Juliana da Silva Fonseca, Roberta Daniele Klein, Adalto Bianchini
Summary: In this study, oxidative stress markers in tetra Hyphessobrycon luetkenii from a copper contaminated creek in southern Brazil were examined. Fish were translocated between polluted and clean locations for experimental tests. The results showed similar trends in oxidative stress indicators between fish from the polluted and clean locations, suggesting adaptations to long-term metal exposure.
BULLETIN OF ENVIRONMENTAL CONTAMINATION AND TOXICOLOGY
(2023)
Article
Environmental Sciences
Mariana F. Martins, Patricia G. Costa, Amanda da S. Guerreiro, Adalto Bianchini
Summary: Coastal elasmobranchs are vulnerable to chemical contaminants due to their life history characteristics and trophic positions. The effects of prenatal exposure to contaminants in embryos of the critically endangered Brazilian guitarfish were investigated. The study found that prenatal exposure to contaminants can impact the redox status in embryos and lead to oxidative damage.
ENVIRONMENTAL POLLUTION
(2023)
Article
Fisheries
Hellyjunyor Brandao, Wellica Gomes dos Reis, Dariano Krummenauer, Wilson Wasielesky Jr
Summary: This study evaluated the reuse of water from a biofloc system after undergoing a biological anaerobic denitrification process on shrimp performance and water quality. The results showed that using a biofloc inoculum in seawater improved productivity and reduced feed conversion ratio, while also serving as a biological treatment in denitrified seawater for shrimp farming.
AQUACULTURE INTERNATIONAL
(2023)
Review
Fisheries
Rodrigo Schveitzer, Roberto Fabio Conway Baccarat, Carlos Augusto Prata Gaona, Wilson Wasielesky, Rafael Arantes
Summary: Microbial flocs (bioflocs) formed by a variety of microorganisms and organic matter are present in intensive shrimp culture tanks. The concentration of total suspended solids (TSS), which quantifies biofloc levels, is important for system performance. However, suggested TSS limits for Pacific white shrimp (Litopenaeus vannamei) in biofloc technology (BFT) have conflicting research results. It is necessary to revisit this topic and find new guidance for biofloc levels in L. vannamei culture tanks.
REVIEWS IN AQUACULTURE
(2023)
Article
Agriculture, Dairy & Animal Science
Grecica Mariana Colombo, Robson Matheus Marreiro Gomes, Sonia Astrid Munoz Buitrago, Juan Rafael Buitrago Ramirez, Alan Carvalho de Sousa Araujo, Fernando Pablo Silva Oliveira, Virginia Fonseca Pedrosa, Luis Alberto Romano, Marcelo Tesser, Wilson Wasielesky, Jose Maria Monserrat
Summary: The study shows that bioflocs were able to assimilate antioxidants from acai and transfer them to juvenile shrimp. The administration of 20 mg acai L-1 resulted in improved intestinal health and lipid damage mitigation. However, high daily doses of acai (80 mg L-1) led to increased mortality and muscle damage in shrimp.
Article
Agriculture, Dairy & Animal Science
Thaise Dalferth Zancan, Jose Maria Monserrat, Robson Matheus Marreiro Gomes, Vilasia Guimaraes Martins, Wilson Wasielesky Jr, Marcelo Borges Tesser
Summary: The effects of including pumpkin seeds and pomace in the diets of Pacific white shrimp Penaeus vannamei were evaluated. The inclusion of pumpkin seeds impaired growth performance and reduced flavonoid content, while including pumpkin pomace did not affect growth performance and improved feed conversion ratio and antioxidant activity.
Article
Fisheries
Kim Catalani, Rodrigo Zuniga, Marcio Silva de Souza, Wilson Wasielesky, Geraldo Foes
Summary: This study compared the use of biofloc technology and aquamimicry technologies in Litopenaeus vannamei lined ponds, and found that both treatments demonstrated efficiency in shrimp production and effective control of water quality.
BOLETIM DO INSTITUTO DE PESCA
(2023)
Article
Fisheries
Marcos Souza de Almeida, Regio Marcio Toesca Gimenes, Plinio Schmidt Furtado, Luis Henrique Poersch, Wilson Junior, Geraldo Kipper Foes, Juliana Rosa Carrijo-Mauad
Summary: This study compared the bioeconomic viability of biofloc and super-intensive shrimp production methods and found that super-intensive production in a greenhouse is the best investment option.
BOLETIM DO INSTITUTO DE PESCA
(2022)
Article
Fisheries
Cleber Dos Santos Simiao, Grecica Mariana Colombo, Robson Matheus Marreiro Gomes, Patricia Baptista Ramos, Marcelo Borges Tesser, Wilson Wasielesky Junior, Jose Maria Monserrat
Summary: This study investigated the chemoprotection of buriti Mauritia flexuosa in Litopenaeus vannamei postlarvae exposed to ammonia or nitrite. The results showed a dose-dependent relationship between the inclusion levels of buriti and carotenoid content, antioxidant capacity, and oxidative damage. The inclusion of buriti in the diet increased scavenging activity and reduced lipid peroxidation in ammonia or nitrite-exposed organisms.
BOLETIM DO INSTITUTO DE PESCA
(2022)
Article
Multidisciplinary Sciences
Daniel P. Da Costa, Marcio Jose S. Silva, Ricardo Marcelo Geraldi, Joao Paulo Lorenzini, Cristiano C. Mattioli, Afonso De Liguori Oliveira, Ronald K. Luz, Kleber Campos Miranda-Filho
Summary: The study aimed to test the retention capacity of carotenoids in tissues of Lophiosilurus alexandri juveniles fed diets containing different levels of synthetic astaxanthin. Results showed that the inclusion of astaxanthin did not significantly impact the growth and feed efficiency of the fish. Interestingly, the highest levels of carotenoids in blood and muscle were observed at the 100 mg/kg inclusion level.
ANAIS DA ACADEMIA BRASILEIRA DE CIENCIAS
(2022)
Article
Fisheries
Mariana Holanda, Wilson Wasielesky Jr, Gabriele Rodrigues de Lara, Luis H. Poersch
Summary: Integrating marine shrimp and tilapia in a biofloc system is a viable alternative, and the multitrophic system with separate tanks for each species performs the best, with tilapia effectively controlling bioflocs.
Article
Biochemistry & Molecular Biology
Gabriela Maressa Machado Baesso, Amanda Vitoria Venancio, Livia Costa Varela Barca, Pepita Fernanda Peppi, Caique Aparecido Faria, Joao Pedro Cosmo Machado, Luiz David Solis Murgas, Alvaro Jose de Almeida Bicudo, Eduardo Mauricio Mendes de Lima, Andre Rodrigues da Cunha Barreto-Vianna
Summary: This study evaluated the effects of eugenol, menthol, and lidocaine as anesthetics on glucose levels and recovery times in zebrafish. The results showed that eugenol and menthol did not affect glucose levels, while lidocaine caused non-concentration-dependent hyperglycemia. Recovery times were similar for eugenol and menthol, but concentration-dependent for lidocaine. Eugenol and menthol were deemed safe and satisfactory for glucose analysis in zebrafish research, while lidocaine could introduce biases and safety concerns. Researchers should carefully consider the selection of anesthetics for reliable results in zebrafish assessments.
COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY C-TOXICOLOGY & PHARMACOLOGY
(2024)
Article
Biochemistry & Molecular Biology
Xiaoxue Li, Tangsong Feng, Weiqun Lu
Summary: This study reveals that exposure to VPA induces ASD-like phenotypes and behaviors, including gene transcription changes, social interaction deficit, decreased aggression, increased anxiety behavior, and elevated cortisol levels. The aggression behavior assay is a better predictor of neurotoxicology behavior of VPA.
COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY C-TOXICOLOGY & PHARMACOLOGY
(2024)
Article
Biochemistry & Molecular Biology
Garam An, Junho Park, Whasun Lim, Gwonhwa Song
Summary: In this study, we investigated the hepatotoxicity and mechanism of action of pyridaben using zebrafish and ZFL cells. Pyridaben caused liver size reduction and apoptosis, and these effects were associated with uncontrolled intracellular calcium flow and downregulation of the PI3K/Akt signaling cascade.
COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY C-TOXICOLOGY & PHARMACOLOGY
(2024)
Article
Biochemistry & Molecular Biology
Md Alamgir Kabir, Md. Golam Rabbane, Marco R. Hernandez, Md Aftab Ali Shaikh, Mohammad Moniruzzaman, Xuexiu Chang
Summary: This study investigated the toxicity of high concentrations of cadmium (Cd) on intestinal immunity and microbial diversity in common carp. The results showed that high Cd concentration caused intestinal inflammation, immunosuppression, and changes in the gut microbiome, leading to detrimental effects on the intestinal homeostasis and health status of the fish.
COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY C-TOXICOLOGY & PHARMACOLOGY
(2024)
Article
Biochemistry & Molecular Biology
Anuradha Batabyal, Veronica Rivi, Cristina Benatti, Johanna M. C. Blom, Fabio Tascedda, Ken Lukowiak
Summary: This study found that exposure to heat shock stressors and bacterial lipopolysaccharide can induce the Garcia effect in pond snails. Additionally, aspirin can prevent the formation of the Garcia effect. However, unexpectedly, exposure to crushed aspirin and heat shock stressors together leads to long-lasting feeding suppression and molecular changes in the snails' serotoninergic system and neuroplasticity genes.
COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY C-TOXICOLOGY & PHARMACOLOGY
(2024)
Article
Biochemistry & Molecular Biology
Li-Yih Lin, Chieh-An Cheng, Sian-Tai Liu, Jiun-Lin Horng
Summary: This study reveals that ammonia exposure impairs ion regulation in zebrafish embryos by inducing oxidative stress, mitochondrial dysfunction, and cell death. The findings suggest that ammonia is toxic to aquatic animals and can lead to the death of embryos.
COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY C-TOXICOLOGY & PHARMACOLOGY
(2024)
Article
Biochemistry & Molecular Biology
Antonio Durate Pagano, Natieli Machado Goncalves, William Borges Domingues, Tony Leandro Rezende da Silveira, Mateus Tavares Kutter, Antonio Sergio Varela Jr, Carine Dahl Corcini, Mariana Cavalcanti Nascimento, Luana Ferreira Viana dos Reis, Patricia Gomes Costa, Adalto Bianchini, Matheus Vieira Volcan, Mariana Harter Remia, Vinicius Farias Campos
Summary: This study analyzed the toxic effects of Roundup Transorb (R) on the endangered Neotropical annual killifish Austrolebias charrua by evaluating molecular and biochemical biomarkers. The findings showed that exposure to Roundup significantly increased the production of reactive oxygen species, lipid peroxidation, and DNA damage in the fish's blood cells. It also decreased membrane fluidity. Gene expression analysis revealed alterations in genes associated with oxidative stress and antioxidant defense. This study provides new insights into adaptive mechanisms of A. charrua in response to Roundup, and it has important implications for environmental monitoring and aquatic toxicology assessment.
COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY C-TOXICOLOGY & PHARMACOLOGY
(2024)
Article
Biochemistry & Molecular Biology
Xiaochan Gao, Hongtao Ren, Yong Huang, Yimin Li, Jiaqi Shen
Summary: The influence of multi-walled carbon nanotubes (MWCNTs) on the toxicity of zinc oxide nanoparticles (ZnONPs) in the intestine of common carp was investigated. The study found that the concentration and concentration ratio of the mixture played a role in the toxicity of ZnONPs. The presence of MWCNTs significantly decreased intercellular zinc accumulation and altered the microbial community diversity and composition of the gut microbiota.
COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY C-TOXICOLOGY & PHARMACOLOGY
(2024)
Article
Biochemistry & Molecular Biology
Guangchao Yang, Qian Yang, Trust Beta, Qin Liu, Zhenzhu Zhu, Fei Shen
Summary: The study found that black garlic MLDs have alleviative effects on ZEN-induced toxicity, and exert their effects through antioxidative, anti-apoptotic, and inhibitory mechanisms on ZEN absorption.
COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY C-TOXICOLOGY & PHARMACOLOGY
(2024)
Article
Biochemistry & Molecular Biology
Tuul Sepp, Ciara Baines, Randel Kreitsberg, Joern Peter Scharsack, Pedro Nogueira, Thomas Lang, Jerome Fort, Elin Sild, John T. Clarke, Arvo Tuvikene, Richard Meitern
Summary: Environmental factors can cause cancer in both wild animals and humans. The use of polluted habitats provides opportunities to study cancer defense mechanisms, which can be influenced by genetic variation and natural selection. Flatfish species, specifically flounders, show higher resistance to pollution-induced cancer compared to dabs, with elevated pollutant metabolism and stronger tumor suppression mechanisms in their liver tissue. This suggests a potential hormetic upregulation of tumor suppression or stronger natural selection pressure for cancer resistance in flounders. Wild species offer valuable insights into understanding the nature and evolution of natural cancer defense mechanisms.
COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY C-TOXICOLOGY & PHARMACOLOGY
(2024)
Article
Biochemistry & Molecular Biology
Regan A. Moss, Kaitlyn M. Murphy, Steven T. Gardner, Madison M. Watkins, John W. Finger Finger Jr, Meghan D. Kelley, Ruth M. Elsey, Daniel A. Warner, Mary T. Mendonca
Summary: The study explored the impact of environmentally relevant concentrations of E2 on the immune system and hormone levels of hatchling American alligators. Results showed that exposure to environmental estrogen can alter plasma hormone concentrations but have little to no impact on morphology and immune responses.
COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY C-TOXICOLOGY & PHARMACOLOGY
(2024)
Article
Biochemistry & Molecular Biology
Ye Liang, Zihao Li, Jing Yuan, Yiwen Zhou, Meng Li, Haifeng Gu
Summary: This study investigated the toxicity mechanism of homo-YTX and NH3-N on the survival of abalone. The results showed that homo-YTX and NH3-N enhanced oxidative stress and lipid peroxidation reactions, inhibited energy supply, disrupted metabolic and immune physiological functions, and activated apoptosis in the gills of abalone.
COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY C-TOXICOLOGY & PHARMACOLOGY
(2024)