Article
Immunology
Valerie Cornet, Trinh Dinh Khuyen, Syaghalirwa N. M. Mandiki, Stephane Betoulle, Peter Bossier, Felipe E. Reyes-Lopez, Lluis Tort, Patrick Kestemont
Summary: Beta-glucans, prebiotic and/or food additives used in aquaculture, have varying effects on fish immune response and disease resistance. Gas1 beta-glucan may be more efficient in enhancing immunity and preventing diseases compared to other types already in use.
FRONTIERS IN IMMUNOLOGY
(2021)
Article
Fisheries
Seyedeh Mitra Aghili, Farid Firouzbakhsh, Sara Haghparast, Ayoub Farhadi
Summary: This research shows that turmeric powder and black pepper have positive effects on growth, blood, and immunity parameters in rainbow trout. The highest values of growth parameters were observed in fish fed with a 1% diet of 70% turmeric and 30% black pepper. Significant changes were also observed in blood counts and immune parameters.
AQUACULTURE INTERNATIONAL
(2023)
Article
Fisheries
Daniel E. Saenz-Martinez, Paula A. Santana, Monica Arostica, Juan C. Forero, Fanny Guzman, Luis Mercado
Summary: The C-terminal end of IL-8 can be cleaved under acidic conditions, retaining its antibacterial properties and detectable in tissues of infected rainbow trout.
DEVELOPMENTAL AND COMPARATIVE IMMUNOLOGY
(2021)
Article
Immunology
Hesham Nasser, Naofumi Takahashi, Youssef M. Eltalkhawy, Omnia Reda, Sameh Lotfi, Kanako Nasu, Jun-ichi Sakuragi, Shinya Suzu
Summary: IL-32 inhibits HIV-1 production in MDMs through SAMHD1, but stimulates viral production in CD4(+) T cells. IL-32 also induces the expression of immunosuppressive molecules such as IDO1 and PD-L1, and promotes MDMs' mobility.
JOURNAL OF IMMUNOLOGY
(2022)
Article
Physiology
Irene Garcia-Meilan, Lluis Tort, Ali Reza Khansari
Summary: The study aimed to determine the integrated stress response in rainbow trout after acute hypoxia. The results showed that physiological responses were significantly affected by hypoxic stress and their interaction with time after the challenge. The study also revealed the importance of different elements and areas of the stress response, including systemic and mucosal responses, in maintaining homeostasis.
FRONTIERS IN PHYSIOLOGY
(2022)
Article
Fisheries
Yue Chong Yang, Shan Nan Chen, Zhen Gan, Lin Huang, Nan Li, Kai Lun Wang, P. Nie
Summary: This study cloned IL-18R alpha, IL-18R beta, and IL-18BP genes from rainbow trout and found that they possess conserved domains with their mammalian orthologues. Results showed that IL-18R alpha and IL-18R beta have low basal expression levels in multiple organs/tissues, while IL-18BP has tissue-specific expression. Transfection experiments demonstrated that recombinant IL-18 can activate NF-kappa B signaling pathway when both pcDNA3.1-IL-18R alpha/IL-1R1 and pcDNA3.1-IL-18R beta/IL-1RAP are expressed. Recombinant receptors also significantly down-regulate NF-kappa B activity, suggesting the involvement of IL-18R alpha, IL-18R beta, and IL-18BP in rainbow trout IL-18 signal transduction. Co-IP assays indicated that IL-18R beta may interact with MyD88, IRAK4, IRAK1, TRAF6, and TAB2, suggesting its association with these signaling molecules in the IL-18 signaling pathway.
DEVELOPMENTAL AND COMPARATIVE IMMUNOLOGY
(2023)
Article
Marine & Freshwater Biology
Aline Ferain, Eva Delbecque, Ineke Neefs, Helene Dailly, Nancy De Saeyer, Melusine Van Larebeke, Valerie Cornet, Yvan Larondelle, Jean-Francois Rees, Patrick Kestemont, Karel A. C. De Schamphelaere, Cathy Debier
Summary: The study found that both dietary lipids and Cd exposure influenced fatty acid metabolism in fish. The hepatic fatty acid profile mostly reflected that of the diet, with selective retention of certain long chain polyunsaturated fatty acids (LC-PUFAs) and active bioconversion of dietary LA and ALA.
AQUATIC TOXICOLOGY
(2021)
Article
Fisheries
Parviz Hassanzadeh, Mohammad Ahmadvand, Shadi Aslani, Najmeh Sheikhzadeh, Shalaleh Mousavi, Seyed Amin Khatibi, Mahmoud A. O. Dawood, Ehsan Ahmadifar
Summary: This study investigated the effects of feeding astaxanthin on rainbow trout. The results showed that feeding astaxanthin improved growth performance and attenuated oxidative stress.
AQUACULTURE RESEARCH
(2022)
Article
Biology
Mais Jubouri, Giancarlo G. M. Talarico, Jean-Michel Weber, Jan A. Mennigen
Summary: The study demonstrates that alanine inhibits glucose metabolism in rainbow trout, leading to a reduction in blood glucose levels. This effect is likely mediated through stimulation of insulin secretion and involves specific gene expression changes in muscle, differing from the mechanisms observed in mammals.
JOURNAL OF EXPERIMENTAL BIOLOGY
(2021)
Article
Genetics & Heredity
Mohamed Salem, Rafet Al-Tobasei, Ali Ali, Brett Kenney
Summary: This study investigated the DNA methylation and gene expression in rainbow trout muscle, focusing on the association between methylation levels and muscle atrophy. The results showed that hypermethylation of CpG sites near the transcription start site was weakly/moderately associated with reduced gene expression, while hypermethylation of CpG sites in downstream regions was weakly associated with increased gene expression. Only a small number of CpGs were differentially methylated, and these were primarily associated with muscle atrophy. The study also identified potential epigenetic markers and genes involved in muscle atrophy in rainbow trout.
Article
Fisheries
Julia Mougin, Victor Lobanov, Morgane Danion, Roxane Roquigny, Lionel Goardon, Thierry Grard, Thierry Morin, Laurent Labbe, Alyssa Joyce
Summary: Misuse and overuse of antibiotics in aquaculture leads to bacterial resistance. Using immunostimulants in fish diets, specifically fungal and herbal compounds, is a sustainable alternative. This study evaluates the effects of fungal and herbal additives on rainbow trout, showing positive immune and gut microbiota responses without adverse effects on growth and survival. The findings contribute to the understanding and potential commercial use of immunostimulant compounds as feed supplements.
FISH & SHELLFISH IMMUNOLOGY
(2023)
Article
Environmental Sciences
N. Hodkovicova, A. Hollerova, J. Blahova, P. Mikula, M. Crhanova, D. Karasova, A. Franc, S. Pavlokova, J. Mares, E. Postulkova, F. Tichy, P. Marsalek, J. Lanikova, M. Faldyna, Z. Svobodova
Summary: The study revealed the toxic effects of NSAIDs on the kidneys, liver, and gills of rainbow trout, with kidneys being the most affected organ, potentially leading to impaired oxygen transport. Furthermore, NSAIDs also impact the microbiota, causing gut dysbiosis.
SCIENCE OF THE TOTAL ENVIRONMENT
(2022)
Article
Fisheries
Lina Weirup, Alexander Rebl, Carsten Schulz, Henrike Seibel
Summary: The welfare of rainbow trout in aquaculture settings was studied using gene expression analysis and other welfare indicators. The study found significant differences in welfare indicators and gene expression profiles among farms with different environmental and management conditions. Farms with high water supply, fast water exchange, and lower stocking densities showed lower levels of external morphological damage in the fish.
Article
Environmental Sciences
Charlotte Bourdon, Patrice Couture, Pierre-Yves Gourves, Christelle Clerandeau, Patrice Gonzalez, Jerome Cachot
Summary: Copper pyrithione (CuPT) exhibits marked toxicity towards early life stages of fish, leading to high accumulation of copper in larvae. It induces higher larval mortality and greater effects on larval development and growth compared to CuSO4, and requires higher concentrations to induce expression of genes involved in oxidative stress defence, detoxification, and copper transport.
ENVIRONMENTAL TOXICOLOGY AND PHARMACOLOGY
(2023)
Article
Environmental Sciences
Shannon Weeks Santos, Patrice Gonzalez, Bettie Cormier, Nicolas Mazzella, Aurelie Moreira, Christelle Clerandeau, Benedicte Morin, Jerome Cachot
Summary: The study found that subchronic exposure to environmental concentrations of CPF could lead to sublethal effects on early-life stages of rainbow trout, especially affecting swimming activity which could impact foraging behavior and predator avoidance.
ENVIRONMENTAL TOXICOLOGY AND CHEMISTRY
(2021)
Article
Biochemistry & Molecular Biology
Fuqiang Ge, Qiaoling Yu, Jun Zhang, Yaoyao Han, Dongfa Zhu, Xi Xie
Summary: The E93 gene was identified and found to be widely distributed in adult tissues of the swimming crab. The expression levels of PtE93 mRNA in Y-organ and epidermis fluctuated during the molt cycle, suggesting its involvement in juvenile molting. Treatment with 20E induced PtE93 expression, while treatment with MF showed the opposite effect. The study also observed a negative correlation between PtE93 and ecdysteroid biosynthesis genes.
COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY B-BIOCHEMISTRY & MOLECULAR BIOLOGY
(2024)
Article
Biochemistry & Molecular Biology
Manuel Marrero, Oscar Monroig, Jose A. Perez, Monica B. Betancor, Ana Galindo, Ana Bolanos, N. Guadalupe Acosta, Covadonga Rodriguez
Summary: This study investigated the combined effects of partial dietary replacement of fish oil (FO) by vegetable oil (VO) and reduced ambient salinity on the fatty acid composition of C. labrosus juveniles. The results showed that C. labrosus is able to biosynthesise EPA and DHA from ALA, and low salinity conditions can upregulate the gene expression related to fatty acid metabolism. Fish reared on FO20 diet showed the highest amount of n-3 LC-PUFA in muscle.
COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY B-BIOCHEMISTRY & MOLECULAR BIOLOGY
(2024)
Article
Biochemistry & Molecular Biology
Davide Degli Esposti, Aureline Lalouette, Karen Gaget, Louveline Lepeule, Zineb Chaabi, Maxime Lepretre, Anabelle Espeyte, Nicolas Delorme, Herve Queau, Laura Garnero, Federica Calevro, Arnaud Chaumot, Olivier Geffard
Summary: Metal pollution has significant effects on aquatic environments, and metallothioneins play important roles in maintaining metal homeostasis and detoxification. This study identified two metallothionein-coding transcripts in Gammarus fossarum and investigated their organ-specific expression patterns. The results showed that mt1 was more strongly induced after cadmium exposure, and mt1 was more highly induced in the caeca compared to the gills for any metal exposure. Additionally, mt2 was more inducible in the gills than in the caeca for cadmium and zinc exposure at the individual level.
COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY B-BIOCHEMISTRY & MOLECULAR BIOLOGY
(2024)
Article
Biochemistry & Molecular Biology
Cuihong You, Shuangshuang Miao, Zhiyong Xie, Siyuan Lin, Shuqi Wang, Cuiying Chen, Li Lin, Yanhua Huang, Meng Zhou, Yewei Dong, Yuanyou Li, Ping Zhuang
Summary: The rabbitfish S. guttatus was found to have the capability for LC-PUFA biosynthesis, with the expression of related genes varying temporally and spatially during embryogenesis and being influenced by ambient salinity.
COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY B-BIOCHEMISTRY & MOLECULAR BIOLOGY
(2024)
Article
Biochemistry & Molecular Biology
Saydur Rahman, Mohammad Maruf Billah, Victor Rangel, Esmirna Cantu
Summary: Global warming has severe impacts on the reproductive fitness of marine invertebrates. In this study, the researchers used various techniques to investigate the effects of high temperatures on global DNA methylation, cellular apoptosis, and nitrative stress in the gonads of Atlantic sea urchins.
COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY B-BIOCHEMISTRY & MOLECULAR BIOLOGY
(2024)
Article
Biochemistry & Molecular Biology
E. S. Kladchenko, A. A. Tkachuk, M. S. Podolskaya, A. Yu. Andreyeva
Summary: This study investigated the osmotic stability and cellular responses of hemocytes in Mediterranean mussel and Pacific oyster. The results revealed that both species showed cellular volume changes and alterations in mitochondrial membrane potential upon hypoosmotic swelling. These findings provide insights into the cellular responses of bivalve mollusks to osmotic stress.
COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY B-BIOCHEMISTRY & MOLECULAR BIOLOGY
(2024)
Article
Biochemistry & Molecular Biology
Yuya Ohhara, Chiemi Sagisaka, Kimiko Yamakawa-Kobayashi
Summary: This study investigated the biosynthetic capacity of n-3 PUFAs in the terrestrial invertebrate Sinella dubiosa, and found that it can metabolize oleic, linolenic, and arachidonic acids to produce EPA, suggesting that it may serve as an EPA source in soil ecosystems.
COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY B-BIOCHEMISTRY & MOLECULAR BIOLOGY
(2024)
Correction
Biochemistry & Molecular Biology
N. Perales-Garcia, D. Tovar-Ramirez, M. G. Martinez-Morales, B. P. Ceballos-Vazquez, D. A. Corona-Rojas, M. A. Salcedo-Meza, A. Garrido-Mora, F. Vega-Villasante, H. Nolasco-Soria
COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY B-BIOCHEMISTRY & MOLECULAR BIOLOGY
(2024)
Article
Biochemistry & Molecular Biology
N. Perales-Garcia, D. Tovar-Ramirez, M. G. Martinez-Morales, B. P. Ceballos-Vazquez, D. A. Corona-Rojas, M. A. Salcedo-Meza, A. Garrido-Mora, F. Vega-Villasante, H. Nolasco-Soria
Summary: This study provides the first report on the digestive tract pH of the pygmy octopus. The pH of the digestive tract regions was found to be lower than 7.0 and did not differ significantly between wild and captive octopuses. The digestive gland had the lowest pH values, but they were still above 5.0.
COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY B-BIOCHEMISTRY & MOLECULAR BIOLOGY
(2024)
Article
Biochemistry & Molecular Biology
Carlos Espirito-Santo, Carmen Alburquerque, Francisco A. Guardiola, Rodrigo O. A. Ozorio, Leonardo J. Magnoni
Summary: Swimming has physiological effects on farmed fish, but the potential link between swimming and oxidative stress is still poorly understood. This study investigated the impact of different moderate swimming conditions on the antioxidant status of gilthead seabream, revealing that swimming modulated the activity of antioxidant enzymes in the liver and skeletal muscle. Adequate swimming conditions were found to minimize oxidative stress in gilthead seabream.
COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY B-BIOCHEMISTRY & MOLECULAR BIOLOGY
(2024)
Article
Biochemistry & Molecular Biology
Yingxin Zhang, Chaobin Qin, Junli Wang, Liping Yang, Xiao Yan, Shaoyang Zhi, Guoxing Nie
Summary: The study focuses on the expression patterns of PFK genes in response to glucose, insulin, and glucagon stimuli in grass carp. The findings suggest that PFK family genes have different or even opposite expression patterns in various tissues, which may contribute to glucose intolerance in fish.
COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY B-BIOCHEMISTRY & MOLECULAR BIOLOGY
(2024)
Article
Biochemistry & Molecular Biology
Jianshuang Li, Likang Lyu, Haishen Wen, Yun Li, Xiaojie Wang, Yijia Yao, Xin Qi
Summary: This study investigated the transcriptional regulation of estrogen receptors (ESRs) on isotocin receptors (itrs) in guppies, and found that estrogen can regulate oxytocin receptor expression in ovoviviparous teleosts. The study also demonstrated that ESR1 represses itr2 promoter activity in an estrogen-dependent manner, while overexpression of ESR2a or ESR2b enhances itr2 promoter activity.
COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY B-BIOCHEMISTRY & MOLECULAR BIOLOGY
(2024)
Article
Biochemistry & Molecular Biology
Wan-Xin Li, Li-Ting Cai, Yan-Ping Huang, Yuan-Qing Huang, Shu-Hui Pan, Zhi-Long Liu, Charles Brighton Ndandala, Gang Shi, Si-Ping Deng, Hong-Juan Shi, Guang-Li Li, Dong-Neng Jiang
Summary: In this study, it was found that S. argus has two lep genes, with lepa highly expressed in the liver and lepb not detected in any tissue. lepa was found to play a role in regulating female reproduction in S. argus.
COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY B-BIOCHEMISTRY & MOLECULAR BIOLOGY
(2024)
Article
Biochemistry & Molecular Biology
Li-Xiang Wu, Xiao-Ying Tan, Yi-Chuang Xu, Hua Zheng, Xiao-Lei Wei, Wu-Hong Lv, Zhi Luo
Summary: This study investigates the mechanisms underlying the activation of lipophagy in yellow catfish under high glucose-induced lipid deposition. The SIRT1-NRF2-TFEB pathway is proposed to mediate lipophagy activation, and lipophagy helps alleviate high glucose-induced lipid deposition. This study provides insights into the control of lipophagy in response to metabolic stress.
COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY B-BIOCHEMISTRY & MOLECULAR BIOLOGY
(2024)