Article
Biochemistry & Molecular Biology
Alicja Pakiet, Kinga Sikora, Jarek Kobiela, Olga Rostkowska, Adriana Mika, Tomasz Sledzinski
Summary: This study identified significant differences in lipid composition between cancer tissue and tumor adjacent tissue in colorectal cancer patients, with 67 lipid compounds showing significant alterations. Many of these lipid compounds are bioactive and can influence cancer development. Increases in phospholipids and sphingolipids, major components of cell membranes, were also observed, which can lead to changes in cell membrane properties.
LIPIDS IN HEALTH AND DISEASE
(2021)
Article
Engineering, Multidisciplinary
Ibrahim Ahmad Ibadurrohman, Nurkholis Hamidi, Lilis Yuliati
Summary: The study found that the degree of unsaturation affects the combustion characteristics of biodiesel, with molecules containing allyl groups accelerating hydrogen atom abstraction and leading to higher burning parameters. Therefore, a high concentration of linoleic methyl ester is recommended in biodiesel, but caution should be taken regarding soot formation at higher levels of unsaturation.
ALEXANDRIA ENGINEERING JOURNAL
(2022)
Article
Food Science & Technology
Santiago P. Aubourg, Marcos Trigo, Maria Jesus Gonzalez, Salome Lois, Isabel Medina
Summary: A novel approach of bioactive lipid extraction using different green solvents was conducted on squid by-products. The results showed that ethanol-containing systems led to higher lipid yields and better fatty acid composition compared to the traditional chloroform/methanol extraction.
Article
Food Science & Technology
S. Kacar, M. Bashan, C. Keskin
Summary: In this study, the fatty acid composition of breast milk was analysed using 25 colostral and 25 mature milk samples collected at different lactational stages. Gas-chromatography was employed to perform transmethylation and analysis of the milk lipid extracts. The major components of total lipid, phospholipid, and triacylglycerol fractions were palmitic acid, stearic acid, myristic acid, oleic acid, and linoleic acid. Colostrum had lower levels of PUFAs and higher levels of SFAs compared to mature milk, and the levels of EPA and DHA in total lipid were lower in colostrum. There were no statistical differences in triacylglycerol and phospholipid fractions between colostrum and mature milk samples.
Article
Chemistry, Analytical
Paola Arena, Danilo Sciarrone, Paola Dugo, Paola Donato, Luigi Mondello
Summary: Triacylglycerols (TAGs), as the main components of edible oils and animal fats, play a crucial role in determining the nutritional value, organoleptic properties, and technological features of foods. Each lipid matrix exhibits a distinct TAG profile, serving as a fingerprint to ensure the quality and authenticity of food products. In this study, the TAG profile of borage seed oil was analyzed using two-dimensional comprehensive liquid chromatography (LCxLC), identifying a total of 94 TAG compounds with varying unsaturation levels and partition values. This analytical approach may be valuable in quickly identifying TAG components in oil samples.
Article
Chemistry, Applied
Luis Gaspar, Fernando Ricardo, Tania Melo, Pedro Domingues, M. Rosario Domingues, Ricardo Calado, Felisa Rey
Summary: The present study performed the first fingerprinting of the polar lipidome of Octopus vulgaris, identifying nearly 400 lipid species from 13 classes of polar lipids. The study highlighted the presence of phosphatidylcholine and phosphatidylethanolamine as the main phospholipids, and ceramides as the main sphingolipids. Additionally, a high proportion of essential fatty acids were found.
JOURNAL OF FOOD COMPOSITION AND ANALYSIS
(2023)
Article
Pharmacology & Pharmacy
An-Kuo Chou, Yu-Wen Chen
Summary: This study found that the combination of L-NAME and lidocaine can enhance and prolong cutaneous analgesia, and also enhance the potency of spinal anaesthesia.
JOURNAL OF PHARMACY AND PHARMACOLOGY
(2023)
Article
Biochemistry & Molecular Biology
Linda Molteni, Bruno Charlier, Viviana Izzo, Albino Coglianese, Valeria Conti, Roberto Eleopra, Roberto Cilia, Chiara Capelli, Annachiara D'Urso, Ugo de Grazia
Summary: Levodopa is an effective treatment for Parkinson's disease, but its complex pharmacokinetics leads to variability in motor response and increases the risk of fluctuations and dyskinesia. Therefore, therapeutic monitoring of Levodopa is crucial to provide personalized therapy and improve drug efficacy and safety.
Article
Mycology
Christopher M. Wallis, Daniel P. Lawrence, Renaud Travadon, Kendra Baumgartner
Summary: Fatty acid methyl ester (FAME) analyses were conducted on 14 fungal species causing grapevine trunk diseases, revealing specific fatty acids contributing to species discrimination. The use of FAME profile libraries and commercial software enabled accurate species-level identification with low sample reassessment rates. However, FAME profiles should not be used for phylogenetic relationships due to significant incongruences with dendrograms based on internal transcribed spacer (ITS) region sequences.
Proceedings Paper
Materials Science, Multidisciplinary
P. Kanthasamy, V. Arul Mozhi Selvan
Summary: Solid wastes generated in the leather industry can be turned into value-added products by recovering leather fleshing fats. This is done through processes such as esterification and transesterification to produce biodiesel.
MATERIALS TODAY-PROCEEDINGS
(2021)
Article
Green & Sustainable Science & Technology
Chinedu Matthew Agu, Matthew Chukwudi Menkiti, Albert Chibuzor Agulanna, Bernad I. Okolo, Kenechi Nwosu-Obieogu
Summary: This study focuses on the modeling of methyl ester yield obtained from the transesterification of Terminalia catappa L. kernel oil using Artificial Neural Network and Response Surface Methodology. The results show that the methyl ester yields were 90.94% and 90.84% under the optimal conditions predicted by the RSM and ANN models, respectively. The physicochemical analysis and GC-MS showed the potential use of the methyl ester as a transformer fluid. Comparing the two models, ANN was deemed as the better predictive model.
CLEANER ENGINEERING AND TECHNOLOGY
(2022)
Article
Food Science & Technology
Claude Lambre, Jose Manuel Barat Baviera, Claudia Bolognesi, Andrew Chesson, Pier Sandro Cocconcelli, Riccardo Crebelli, David Michael Gott, Konrad Grob, Evgenia Lampi, Marcel Mengelers, Alicja Mortensen, Inger-Lise Steffensen, Christina Tlustos, Henk Van Loveren, Laurence Vernis, Holger Zorn, Laurence Castle, Emma Di Consiglio, Roland Franz, Nicole Hellwig, Maria Rosaria Milana, Stefan Merkel, Ellen Van Haver, Katharina Volk, Gilles Riviere
Summary: The CEP Panel evaluated the safety of a substance used in high impact polystyrene obtained by reaction, concluding that it does not pose a safety concern if used as an additive at up to 0.025% w/w in ABS copolymers for contact with various types of food under specified conditions.
Article
Physiology
A. Gajos-Draus, M. Duda, A. Beresewicz
Summary: Diabetes-induced vascular pathologies are associated with inflammation mediated by NF-kappa B and Nrf2, with NF-kappa B activation induced by NADPH oxidase 2 and Nrf2 activation by Nox4. The imbalance between these two systems can be prevented by interventions such as exercise training and sodium nitrite, which replenish vascular NO signaling. Inhibition of nitric oxide synthase disrupts the balance, leading to vascular oxidative stress and inflammation, as seen in diabetic rats.
JOURNAL OF PHYSIOLOGY AND PHARMACOLOGY
(2021)
Article
Physiology
Wales A. Carter, Kristen J. DeMoranville, Barbara J. Pierce, Scott R. McWilliams
Summary: The study found that diet and exercise training significantly affect the activity of key oxidative enzymes in songbirds, particularly carnitine palmitoyl transferase and citrate synthase. This suggests a plausible mechanism linking diet quality and metabolic performance in songbirds.
JOURNAL OF COMPARATIVE PHYSIOLOGY B-BIOCHEMICAL SYSTEMS AND ENVIRONMENTAL PHYSIOLOGY
(2021)
Article
Biology
Idan Koren, Sammy Boussiba, Inna Khozin-Goldberg, Aliza Zarka
Summary: Microalgae like Chromochloris zofingiensis are plant-like micro-organisms that can capture light energy through photosynthesis to produce high value pharmaceutical and nutritional pigments. Understanding their growth characteristics is crucial for efficient commercial production. By staining the nucleus of the alga, researchers found that C. zofingiensis cells conduct consecutive DNA synthesis and divisions before dividing into daughter cells. This process is influenced by light conditions and can be applied for high pigment productivity in biotechnological applications.
Article
Ornithology
Luke L. Powell, Adam Metallo, Crinan Jarrett, Nathan W. Cooper, Peter P. Marra, Scott R. McWilliams, Ulf Bauchinger, Bryant C. Dossman
Summary: A noninvasive aluminum muscle meter device was developed to estimate the size of pectoral muscles in birds, and a durable plastic 3D-printed version was created for wider availability. The device showed repeatability among users, correlation with visual scoring systems, and outperformed traditional systems in predicting body condition indices. The precision of the 3D-scanning hardware used to create the device made it as useful as the original aluminum version, but more cost-effective and accessible.
JOURNAL OF FIELD ORNITHOLOGY
(2021)
Article
Ornithology
Lillie A. Langlois, Scott R. McWilliams
Summary: The study found that Hermit Thrushes and White-throated Sparrows have similar requirements for lysine and methionine, but different requirements for arginine. Most birds exhibit various responses when fed diets with inadequate essential amino acid concentrations, but may also overcompensate when consuming diets deficient in certain amino acids.
JOURNAL OF ORNITHOLOGY
(2022)
Article
Environmental Sciences
Ram Chandra Shrestha, Lusine Ghazaryan, Ben Poodiack, Boris Zorin, Avner Gross, Osnat Gillor, Inna Khozin-Goldberg, Ilya Gelfand
Summary: The study found that fertilization with algal biomass reduced wheat grain nitrogen content and soil nitrogen oxide emissions, leading to lower greenhouse gas emissions and global warming impact compared to urea fertilization.
SCIENCE OF THE TOTAL ENVIRONMENT
(2022)
Article
Plant Sciences
Yogesh Taparia, Achintya Kumar Dolui, Sammy Boussiba, Inna Khozin-Goldberg
Summary: This study describes the construction of a modular two-component transcriptional unit system to express SpCas9 in a diatom. The system enables multiplexed targeting and marker-free genome editing. The editing efficiency of the system was evaluated by targeting the StLDP gene, and the results showed the importance of StLDP in lipid droplet regulation.
FRONTIERS IN PLANT SCIENCE
(2022)
Article
Ornithology
Christopher M. Roelandt, Amber M. Roth, Scott R. McWilliams, Jill C. Witt
Summary: The field-usable point-of-care analyzer showed high repeatability and precision in measuring plasma TRIG in male American Woodcock, but was not accurate compared to lab-measured values, possibly due to environmental effects or specific issues with analyzing woodcock blood. This suggests that the analyzer may not provide a reliable alternative method for measuring circulating TRIG in woodcock during cold springs, and a pilot study is recommended before field use for understanding its operating limits.
JOURNAL OF ORNITHOLOGY
(2022)
Article
Ornithology
Clayton L. Graham, Scott R. McWilliams
Summary: The study validated the deuterium dilution method as a nonlethal technique for estimating body composition of shorebirds during fall staging. The results showed high accuracy of the predictive models using deuterium dilution method, while conventionally used morphology-based condition indices were poor predictors of fat mass.
JOURNAL OF ORNITHOLOGY
(2022)
Article
Biology
Edwin R. Price, Ulf Bauchinger, Scott R. McWilliams, Michelle L. Boyles, Lillie A. Langlois, Alexander R. Gerson, Christopher G. Guglielmo
Summary: Migratory birds undergo rapid upregulation of catabolic capacity during flight, with minor effects due to training. Dietary fatty acid composition and antioxidants have no significant effect on muscle catabolic enzymes or lipid transporter expression.
JOURNAL OF EXPERIMENTAL BIOLOGY
(2022)
Article
Biotechnology & Applied Microbiology
Giulia Trentin, Francesca Piazza, Marta Carletti, Boris Zorin, Inna Khozin-Goldberg, Alberto Bertucco, Eleonora Sforza
Summary: Two diazotrophic cyanobacteria were cultivated to produce cyanophycin under nitrogen fixing conditions. Nostoc sp. showed higher efficiency in accumulating cyanophycin and fixing atmospheric nitrogen. The operating conditions were optimized, with nitrogen availability and/or pH playing a major role in biomass production and phosphorus limitation maximizing cyanophycin accumulation.
APPLIED MICROBIOLOGY AND BIOTECHNOLOGY
(2023)
Article
Food Science & Technology
Ekaterina Novichkova, Sagar Nayak, Sammy Boussiba, Jacob Gopas, Dina Zilberg, Inna Khozin-Goldberg
Summary: The study investigates the anti-inflammatory and immunomodulatory potential of the microalga Lobosphaera incisa P127 in the zebrafish model of IBD. Results show that diets containing 15% non-starved (Ns) and 7.5% and 15% nitrogen-starved (St) algal biomass effectively attenuate gut injury, while diets containing 7.5% Ns and DGLA ethyl ester have no effect on gut condition.
MOLECULAR NUTRITION & FOOD RESEARCH
(2023)
Article
Plant Sciences
Avital Friedjung Yosef, Lusine Ghazaryan, Linda Klamann, Katherine Sarah Kaufman, Capucine Baubin, Ben Poodiack, Noya Ran, Talia Gabay, Shoshana Didi-Cohen, Manuela Bog, Inna Khozin-Goldberg, Osnat Gillor
Summary: This study investigates the diversity of duckweeds in Israel and finds that the duckweed population in aquatic environments consists of both native and transient species. The analysis of fatty acids and protein content suggests functional differences among the identified species. Additionally, potential invasive species are identified.
Article
Ecology
Cornelia W. Twining, Jeremy Ryan Shipley, Marshall D. McCue, Ivan Pokrovsky, Arnaud Gregoire, Bruno Faivre, Martin Wikelski, Jesko Partecke
Summary: Seasonal migration is a demanding task for animals, and the energetic demands of migration determine the preparation undertaken by different species and populations. Birds use stored fat as fuel for their migratory flight, and certain lipids like polyunsaturated fatty acids (PUFAs) may play a crucial role in providing efficient fuel and fulfilling additional functions during long-distance migratory flight.
FUNCTIONAL ECOLOGY
(2023)
Review
Biochemical Research Methods
Marshall D. Mccue
Summary: This article reviews the practice of C-13 breath testing in humans and animals, discusses the impact of ambient CO2 contamination on its accuracy, and proposes a mathematical solution to address these issues.
RAPID COMMUNICATIONS IN MASS SPECTROMETRY
(2023)
Editorial Material
Plant Sciences
Zhi-Yan Du, Wajid Waheed Bhat, Guoyin Kai, Inna Khozin-Goldberg, Xiao-Hong Yu, Agnieszka Zienkiewicz, Krzysztof Zienkiewicz
FRONTIERS IN PLANT SCIENCE
(2023)
Article
Biochemistry & Molecular Biology
Sang Hyuck Lee, Mi Ae Kim, Young Chang Sohn
Summary: This study characterized the CCAP signaling system in Pacific abalone and revealed its relationship with the calcium/PKC and cAMP/PKA signal transduction pathways. It provides new insights into the evolutionary origins of the NPS and OT/VP signaling systems in protostomes.
COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY A-MOLECULAR & INTEGRATIVE PHYSIOLOGY
(2024)
Article
Biochemistry & Molecular Biology
Hanna Scheuffele, Erica V. Todd, John A. Donald, Timothy D. Clark
Summary: Global warming is causing an increase in extreme weather events, affecting ecosystems and the behavior of ectotherms. More research is needed to understand the impact of diurnal thermal variability and improve climate change predictions.
COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY A-MOLECULAR & INTEGRATIVE PHYSIOLOGY
(2024)
Article
Biochemistry & Molecular Biology
Jaakko Haverinen, Ahmed Badr, Markus Eskelinen, Matti Vornanen
Summary: The acclimatization of certain ectothermic vertebrates to winter conditions involves reduced energy consumption, achieved through decreased movement activity, depression of cellular functions, or switching to anaerobic energy production. This study on crucian carp showed that winter-acclimatized fish exhibited lower metabolic rates and a shift to anaerobic energy production during anoxia. Winter dormancy in crucian carp is achieved through active reduction of energy consumption, a slowed metabolic rate, and a direct response to oxygen absence.
COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY A-MOLECULAR & INTEGRATIVE PHYSIOLOGY
(2024)
Article
Biochemistry & Molecular Biology
Maria Cruz Sueiro, Cynthia A. Awruch, Gustavo M. Somoza, Walter S. Svagelj, Maria G. Palacios
Summary: According to life-history theory, there might be different immunological strategies between reproductive and non-reproductive periods due to limited resources. Our study on two sympatric marine fish species, rockfish and sandperch, found that reproductive individuals showed lower immune function, but higher levels of natural antibodies in rockfish females, compared to their non-reproductive counterparts. On the other hand, reproductively active sandperch males showed lower levels of natural antibodies and higher neutrophil to lymphocyte ratio and spleen index compared to non-reproductive males. The study highlights the species-specific patterns of immunity and the potential influence of resource limitation and abiotic factors on immune trade-offs in fish.
COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY A-MOLECULAR & INTEGRATIVE PHYSIOLOGY
(2024)
Article
Biochemistry & Molecular Biology
James B. Cummins, Dane A. Crossley II
Summary: This study focuses on cardiovascular development in altricial bird species, which has been less studied compared to precocial species. The researchers investigated the cholinergic and adrenergic receptor mediated control of arterial blood pressure and heart rate in the neotropic cormorant. The findings suggest that both cholinergic and adrenergic tone play a role in cardiovascular regulation in embryonic birds.
COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY A-MOLECULAR & INTEGRATIVE PHYSIOLOGY
(2024)
Article
Biochemistry & Molecular Biology
Ru Xia, Hong-Kang Liu, Xi-Feng Liu, Xin Deng, Chuan-Jie Qin, Yuan-Fa He, Shi-Mei Lin, Yong-Jun Chen
Summary: This study cloned the genes encoding glucokinase and glucose-6-phosphatase catalytic subunit in largemouth bass, revealing their distribution and transcriptional regulation. The results showed that the functions of G6pc and Gck in LMB were highly conserved in evolution, and the interconversion of glucose and G6P in the liver was well regulated at the transcript level under high starch diet, but a futile cycle was induced after a glucose load.
COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY A-MOLECULAR & INTEGRATIVE PHYSIOLOGY
(2024)
