期刊
JOURNAL OF MEDICAL VIROLOGY
卷 88, 期 4, 页码 734-737出版社
WILEY
DOI: 10.1002/jmv.24370
关键词
RT-PCR detection; environment; phylogenetic tree; genotype; non-human primate
类别
资金
- National Research Foundation [UID 85799]
Hepatitis A virus (HAV) was detected, by real-time reverse transcription-polymerase chain reaction, in irrigation water from a dam on a commercial fresh produce farm in South Africa (SA). The virus was characterized by nucleotide sequence and phylogenetic analysis of a consensus sequence spanning the VP1 and VP1/P2B genomic regions. Amino acid sequence and phylogenetic analysis indicated that the HAV strain was closely related to HAV genotype V and possibly of simian origin. This suggests that a novel HAV may be circulating in SA and its presence in irrigation water highlights the potential for zoonotic or anthroponotic cross-species transmission via environmental food and water sources. J. Med. Virol. 88:734-737, 2016. (c) 2015 Wiley Periodicals, Inc.
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