UNC80mutation causes a syndrome of hypotonia, severe intellectual disability, dyskinesia and dysmorphism, similar to that caused by mutations in its interacting cation channelNALCN

Mutations in NALCN Cause an Autosomal-Recessive Syndrome with Severe Hypotonia, Speech Impairment, and Cognitive Delay

(2013) Moeenaldeen D. Al-Sayed et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Isolated foveal hypoplasia with secondary nystagmus and low vision is associated with a homozygous SLC38A8 mutation

(2013) Yonatan Perez et al.   EUROPEAN JOURNAL OF HUMAN GENETICS

Deciphering the fine-structure of tribal admixture in the Bedouin population using genomic data

(2013) B Markus et al.   HEREDITY

Recessive truncatingNALCNmutation in infantile neuroaxonal dystrophy with facial dysmorphism

(2013) Çiğdem Köroğlu et al.   JOURNAL OF MEDICAL GENETICS

UNC79 and UNC80, Putative Auxiliary Subunits of the NARROW ABDOMEN Ion Channel, Are Indispensable for Robust Circadian Locomotor Rhythms in Drosophila

(2013) Bridget C. Lear et al.   PLoS One

A system for exact and approximate genetic linkage analysis of SNP data in large pedigrees

(2012) M. Silberstein et al.   BIOINFORMATICS

Sodium Leak Channels in Neuronal Excitability and Rhythmic Behaviors

(2011) Dejian Ren   NEURON

UNC80 functions as a scaffold for Src kinases in NALCN channel function

(2010) Haikun Wang et al.   Channels

Extracellular Calcium Controls Background Current and Neuronal Excitability via an UNC79-UNC80-NALCN Cation Channel Complex

(2010) Boxun Lu et al.   NEURON

HomozygosityMapper--an interactive approach to homozygosity mapping

(2009) D. Seelow et al.   NUCLEIC ACIDS RESEARCH

Peptide neurotransmitters activate a cation channel complex of NALCN and UNC-80

(2008) Boxun Lu et al.   NATURE

A Putative Cation Channel, NCA-1, and a Novel Protein, UNC-80, Transmit Neuronal Activity in C. elegans

(2008) Edward Yeh et al.   PLOS BIOLOGY