Article
Chemistry, Physical
Catalin Panaghie, Georgeta Zegan, Alina Sodor, Nicanor Cimpoesu, Nicoleta-Monica Lohan, Bogdan Istrate, Ana-Maria Roman, Nicoleta Ioanid
Summary: Biodegradable metallic materials have been widely used in medical applications. This paper investigates the corrosion/degradation products of an experimental material (ZnMgY alloy) after immersion tests in three physiological solutions. The results show that the alloy's microstructure strongly influences the corrosion characteristics and the corrosion products mainly include oxides, hydroxides, carbonates or phosphates.
Article
Nanoscience & Nanotechnology
Andrea Zaffora, Francesco Di Franco, Danilo Virtu, Francesco Carfi Pavia, Giulio Ghersi, Sannakaisa Virtanen, Monica Santamaria
Summary: Coatings were grown on the AZ31 Mg alloy via a hard anodizing process in the hot glycerol phosphate-containing electrolyte. The optimized anodizing conditions and post-anodizing annealing treatment further enhanced the corrosion resistance of the coatings, mainly composed of magnesium phosphate. The coatings exhibited good biocompatibility and are suitable for biomedical devices.
ACS APPLIED MATERIALS & INTERFACES
(2021)
Article
Chemistry, Physical
S. Thanka Rajan, Mitun Das, A. Arockiarajan
Summary: In this study, tantalum oxide thin films were deposited onto the surface of AZ31B alloy using the sputtering process, and their biocompatibility and corrosion resistance were evaluated. The results showed that the Ta-based thin films significantly enhanced the corrosion resistance of the magnesium alloy, exhibited good bioactivity, and had good hemocompatibility.
JOURNAL OF ALLOYS AND COMPOUNDS
(2022)
Article
Chemistry, Physical
Liuzhong Yang, Yan Feng, Yuqing He, Linyi Yang, Hanchuan Liu, Xinfa Wang, Chaoqun Peng, Richu Wang
Summary: The influences of Sc/Sm microalloying on microstructure, mechanical property, bio-corrosion behavior and biocompatibility of the as-cast Mg-2Zn-0.3Ca alloy have been investigated. Sc microalloying refines the grain and improves the yield strength, while Sm microalloying promotes the formation of dispersed particles. Mg-2Zn-0.3Ca-0.4Sm alloy exhibits the best corrosion resistance and protective layer, and is non-cytotoxic and promotes cell proliferation.
JOURNAL OF ALLOYS AND COMPOUNDS
(2022)
Article
Chemistry, Physical
Bangjun Li, Jiapeng Sun, Bingqian Xu, Guosong Wu
Summary: This paper investigates the corrosion behavior of Mg-5.7Gd-1.9Ag alloy sheets in a salt solution. The results show that the rolled sheets exhibit better corrosion resistance compared to the as-cast sheets. Aging treatment decreases corrosion resistance, but it still remains higher than that of the as-cast sheets. The migration of corrosion is mainly influenced by the evolution of second phases rather than grain size and texture.
JOURNAL OF ALLOYS AND COMPOUNDS
(2022)
Article
Materials Science, Multidisciplinary
Mingliang Qiao, Jianchun Sha, Siqi Yin, Wenhong Liu, Zhong Zhao, Jianzhong Cui, Zhiqiang Zhang
Summary: The microstructures, corrosion behavior, biocompatibility, and antimicrobial properties of biodegradable Mg-2Zn-1Gd-0.5Zr-xCu (x - 0, 0.1, 0.3, 0.5 wt.%) alloys were evaluated. The addition of Cu element resulted in the generation of the MgZnCu phase in addition to existing phases in the alloys. The presence of grain boundaries and specific phases acted as physical barriers to hinder corrosion, while the formation of Ca-P compounds and dense oxides improved the corrosion resistance. However, the increase in the content and change in the morphology of the MgZnCu phase enhanced galvanic corrosion and reduced corrosion resistance. The Mg-2Zn-1Gd-0.5Zr-0.1Cu alloy exhibited lower corrosion rate, good biocompatibility, and excellent antibacterial properties, making it a potential biodegradable antimicrobial biomaterial for bone implants.
JOURNAL OF MATERIALS RESEARCH AND TECHNOLOGY-JMR&T
(2022)
Article
Materials Science, Multidisciplinary
Evgeniy Merson, Vitaliy Poluyanov, Pavel Myagkikh, Dmitri Merson, Alexei Vinogradov
Summary: The study demonstrates that stress-corrosion cracking (SCC) in magnesium and its alloys during slow-strain rate tensile testing in air is related to hydrogen embrittlement and the corrosion product layer. However, the complete recovery of mechanical response and elimination of harmful embrittling features can be achieved by removing corrosion products from the surface of pre-exposed specimens, which challenges the common viewpoint that SCC mechanism is solely governed by diffusible hydrogen.
Article
Materials Science, Multidisciplinary
Pi-Chen Lin, Kaifan Lin, Yu-Hsuan Lin, Kai-Chiang Yang, Vladimir Ivanovitch Semenov, Hsin-Chih Lin, Miin-Jang Chen
Summary: Polycrystalline HfZrO2 (HZO) film can enhance the corrosion resistance and reduce the corrosion rate of as-extruded Mg-Ca alloy. Compared to ZrO2 film, HZO film exhibits better short-term corrosion resistance. HZO film shows low toxicity and is suitable for the protective coating of biological implants.
Article
Materials Science, Multidisciplinary
Xiaoxing Li, Runqi Zhou
Summary: The microstructure, mechanical properties, corrosion, wear behavior, and cytocompatibility of in situ Zn-Mg-Mg2Si alloys with different Mg2Si contents were evaluated. Increasing Mg-10Si content improved the mechanical strength, hardness, and wear resistance, but decreased the corrosion rate and cytocompatibility. The Zn-Mg-0.6Mg2Si alloy exhibited the best matching with moderate UTS, YS, hardness, wear loss, degradation rate, and cell viability, making it a preferable candidate for biodegradable bone-implant materials.
Article
Materials Science, Multidisciplinary
Weiyan Jiang, Wenzhou Yu
Summary: The gradient Mg-Si alloy designed for biodegradable orthopedic implant materials shows significant improvement in bio-corrosion resistance, with high polarization resistance, low corrosion current density, and slow corrosion rate. Additionally, the alloy exhibits good osteogenic activity and non-toxicity to cells.
Article
Materials Science, Coatings & Films
Zheng Zhao, Lishuai Zong, Chengde Liu, Wenfei Ding, Linyan Zhu, Chunwei Qi, Chenghao Wang, Shuxin Shao, Jinyan Wang, Xigao Jian
Summary: In this study, a reinforced corrosion control strategy for bioabsorbable Mg alloy stents was proposed by introducing graphene oxide into a poly(trimethylene carbonate) coating. The increase of graphene oxide content in the coating improved its corrosion resistance by prolonging the permeation path of solution, without significantly affecting its cytocompatibility and hemocompatibility. However, excessive graphene oxide content resulted in the formation of defects and a rapid decrease in corrosion resistance.
SURFACE & COATINGS TECHNOLOGY
(2022)
Article
Materials Science, Multidisciplinary
Zheng Zhao, Lishuai Zong, Chengde Liu, Xiangyu Li, Chenghao Wang, Wentao Liu, Xitong Cheng, Jinyan Wang, Xigao Jian
Summary: An inorganic coating was prepared on a bioabsorbable magnesium alloy surface using a simple two-step immersion approach, significantly improving its adhesion and corrosion resistance while maintaining good biocompatibility.
Review
Metallurgy & Metallurgical Engineering
Violeta Tsakiris, Christu Tardei, Florentina Marilena Clicinschi
Summary: In the past decade, there has been significant growth in the market for alloys used for implants, especially in orthopedic implants. Research on biodegradable magnesium-based alloys has made great strides in the medical industry due to the desire to improve quality of life and reduce costs.
JOURNAL OF MAGNESIUM AND ALLOYS
(2021)
Article
Engineering, Biomedical
Wenhui Wang, Carsten Blawert, Rui Zan, Yu Sun, Hongzhou Peng, Jiahua Ni, Pei Han, Tao Suo, Yang Song, Shaoxiang Zhang, Mikhail L. Zheludkevich, Xiaonong Zhang
Summary: The study successfully obtained bulk nanocrystalline Mg alloy with high strength and good corrosion resistance through hot rolling process of a lean Mg-2wt.%Zn alloy. The microstructure evolution during the rolling process was analyzed in depth, providing a new direction for the development of lean biomedical Mg alloys.
BIOACTIVE MATERIALS
(2021)
Article
Materials Science, Multidisciplinary
Hassan Jafari, Amir Houshang Mojiri Tehrani, Mojiri Tehrani, Mahsa Heydari
Summary: The study found that extrusion temperature and ratio have significant effects on the microstructure, hardness, compression, and corrosion behavior of Mg-5Zn-1.5Y alloy. Lower temperature and higher ratio extrusion conditions provided higher compressive strengths, and the extrusion process decreased the corrosion rate of the alloy in simulated body fluid significantly. Extrusion temperature had a more pronounced effect on corrosion resistance compared to the extrusion ratio, with higher temperatures resulting in higher corrosion resistance.
INTERNATIONAL JOURNAL OF MINERALS METALLURGY AND MATERIALS
(2022)
Article
Nanoscience & Nanotechnology
Fiorela Ghilini, Rmiriam C. Rodriguez Gonzalez, Alejandro G. Minan, Diego Pissinis, Alberto Hernandez Creus, Roberto C. Salvarezza, Patricia L. Schilardi
ACS APPLIED MATERIALS & INTERFACES
(2018)
Review
Materials Science, Biomaterials
Fiorela Ghilini, Diego E. Pissinis, Alejandro Minan, Patricia L. Schilardi, Carolina Diaz
ACS BIOMATERIALS SCIENCE & ENGINEERING
(2019)
Article
Dentistry, Oral Surgery & Medicine
Ariel Gonzalez, Alejandro Guillermo Minan, Claudia Alejandra Grillo, Eduardo Daniel Prieto, Patricia Laura Schilardi, Monica Alicia Fernandez Lorenzo de Mele
Article
Nanoscience & Nanotechnology
Eduardo Gonik, Damian Rodriguez Sartori, Pedro David Gara, Alejandro Minan, Monica Fernandez Lorenzo de Mele, Monica C. Gonzalez
Summary: Immobilization of PEG-covered silicon dots on glass substrates was achieved by a simple strategy, forming a water-wettable, strongly supported, photoluminescent glass coating. These films showed high capacity for photosensitizing singlet oxygen in water, leading to inhibition of bacterial adhesion and growth, especially of Staphylococcus aureus. The synergistic effect of a less adherent surface inhibiting biofilm formation, combined with the ability to photosensitize singlet oxygen, successfully eradicated attached bacteria.
Article
Biophysics
Maria Noel Urrutia, Maria Jose Sosa, Diego E. Pissinis, Antonela Canneva, Alejandro G. Minan, Mariana Vignoni, Alejandra Calvo, Andres H. Thomas, Patricia L. Schilardi
Summary: This study successfully immobilized pterin moieties on silicon substrates through a nucleophilic substitution reaction, with a higher proportion of the N-derivative, retaining their photochemical properties and inhibiting Staphylococcus aureus growth under irradiation. The results suggest the potential for modification of various materials with photosensitive surfaces having microbiological self-cleaning properties.
COLLOIDS AND SURFACES B-BIOINTERFACES
(2021)
Article
Chemistry, Multidisciplinary
Damian Rodriguez Sartori, Marcos Bertuola, Alejandro Minan, Eduardo Gonik, Monica C. Gonzalez, Monica Fernandez Lorenzo de Mele
Summary: The study evaluated the effects of environmental factors on the physicochemical properties of MWCNT and their impacts on bacteria growing in biofilms, finding that sunlight irradiation and the presence of HA alter the metal adsorption, HA composition, and bacterial adaptive behavior.
Article
Infectious Diseases
Beatriz Muller Nunes Souza, Juliana Guerra Pinto, Andre Henrique Correia Pereira, Alejandro Guillermo Minan, Juliana Ferreira-Strixino
Summary: The study found that the use of PDZ for antimicrobial photodynamic therapy has a significant bactericidal effect on Staphylococcus aureus, including complete inactivation of MRSA strains.
Article
Ecology
Damian Rodriguez Sartori, Alejandro G. Minan, Monica C. Gonzalez, Monica A. Fernandez Lorenzo de Mele
Summary: The use of metal-based and Al2O3 nanoparticles is increasing, but their impact on groundwater and biological systems is not well-studied. In the presence of Al2O3-NP, Pseudomonas aeruginosa exhibits an adaptive behavior of disassembling 3D structures and forming a 2D network for survival, independent of EPS.
Article
Oncology
Isabelle de Paula Ribeiro, Juliana Guerra Pinto, Beatriz Muller Nunes Souza, Alejandro Guillermo Minan, Juliana Ferreira-Strixino
Summary: Antimicrobial Photodynamic Therapy (aPDT) with curcumin was shown to reduce the growth of MRSA biofilm without cytotoxicity, providing a relevant alternative possibility for the inactivation of this strain.
PHOTODIAGNOSIS AND PHOTODYNAMIC THERAPY
(2022)
Article
Biochemistry & Molecular Biology
Natalia S. Fagali, Marcos A. Madrid, Blanca T. Perez Maceda, Maria E. Lopez Fernandez, Rosa M. Lozano Puerto, Monica Fernandez Lorenzo de Mele
Article
Chemistry, Multidisciplinary
Darlin J. Perez Enriquez, Maria L. Dell'Arciprete, Maria L. Dittler, Alejandro Minan, Eduardo Prieto, Monica C. Gonzalez
NEW JOURNAL OF CHEMISTRY
(2020)
Article
Multidisciplinary Sciences
Maira Gaspar Tosato, Patricia Schilardi, Monica Fernandez Lorenzo de Mele, Andres H. Thomas, Carolina Lorente, Alejandro Minan
Article
Biophysics
Cristina Potrich, Anna Pedrotti, Cecilia Pederzolli, Lorenzo Lunelli
Summary: This study developed different functional surfaces for capturing exosomes and verified their effectiveness through experiments. Among them, the negatively-charged surface performed the best, capturing a large number of exosomes and successfully analyzing their biomarkers.
COLLOIDS AND SURFACES B-BIOINTERFACES
(2024)
Article
Biophysics
Brojendra Nath Saren, Srushti Mahajan, Mayur Aalhate, Rahul Kumar, Essha Chatterjee, Indrani Maji, Ujala Gupta, Santosh Kumar Guru, Pankaj Kumar Singh
Summary: This study developed P-selectin-targeted dasatinib nanoparticles coated with chitosan and fucoidan (DST-CH-FUC-NPs), which showed sustained release, reduced hemolytic potential, increased cytotoxicity and cellular uptake compared to free dasatinib. These nanoparticles also demonstrated enhanced ROS production, mitochondrial membrane potential damage, apoptosis induction, cell migration inhibition, and disruption of lysosomal membrane integrity.
COLLOIDS AND SURFACES B-BIOINTERFACES
(2024)
Article
Biophysics
Weiping Deng, Xiaohui Li, Ya Li, Zhongbing Huang, Yulin Wang, Ning Mu, Juan Wang, Tunan Chen, Ximing Pu, Guangfu Yin, Hua Feng
Summary: This study demonstrates the importance of chirality in nerve repair by constructing a GO-phenylalanine derivative hydrogel system. In vivo experiments show that the dextro group significantly improves functional recovery and histological restoration in rat sciatic nerve repair models. The doped GO promotes angiogenesis and myelination. These results suggest that chirality plays a crucial role in promoting nerve regeneration.
COLLOIDS AND SURFACES B-BIOINTERFACES
(2024)
Article
Biophysics
Xiaoyan Wang, Jin Gao, Yu Gao, Linlin Zhang, Congchao Xu, Qintong Li, Lin Li, Jianliang Xue
Summary: In this study, a highly effective surfactant producer strain, Bacillus Cereus GX7, was isolated from the oil tank bottom sludge of Shengli Oil Field in China. The biosurfactant produced by GX7 was identified as surfactin, a lipopeptide surfactant, through TLC, FT-IR, and LC-MS/MS analysis. The fermentation process of GX7 was optimized using single-factor experiments, focusing on the composition of fermentation medium and fermentation conditions. Glucose and peptone were found to be the best carbon and nitrogen sources, and the optimum temperature, inoculum amount, pH, rotation speed, and fermentation time for the strain were determined to be 30°C, 1%, 7.5, 150 rpm, and 48 h, respectively. After optimization, the surface tension and emulsification index of the fermentation broth were 26.84 mN/m and 57.84%, respectively. Furthermore, the biosurfactant produced by GX7 demonstrated good stability over a wide range of temperature, pH, and salt concentration.
COLLOIDS AND SURFACES B-BIOINTERFACES
(2024)
Article
Biophysics
Rodney Marcelo do Nascimento, Christine Grauby-Heywang, Houssem Kahli, Nesrine Debez, Laure Beven, Ivan Helmuth Bechtold, Touria Cohen Bouhacina
Summary: This article presents a theoretical model based on thermodynamic rules to assess the early stages of bacterial biofilm formation on different material surfaces. By utilizing morphological characteristics of bacteria and Atomic Force Microscopy images, the model generates a dataset of energetically minimized states, which can be correlated with bacterial adhesion states.
COLLOIDS AND SURFACES B-BIOINTERFACES
(2024)
Article
Biophysics
Filipa A. L. S. Silva, Licinia Timochenco, Raquel Costa-Almeida, Jose Ramiro Fernandes, Susana G. Santos, Fernao D. Magalhaes, Artur M. Pinto
Summary: The study demonstrates that by photoreducing nanosized graphene oxide using ultraviolet radiation, nanometric particles with high light-to-heat conversion efficiency and water stability can be obtained. These nanomaterials exhibit high absorption in the near-infrared region and show no cytotoxicity towards human cells, indicating their potential for safe therapy.
COLLOIDS AND SURFACES B-BIOINTERFACES
(2024)
Article
Biophysics
D. Costa, V. De Matteis, F. Treso, G. Montani, M. Martino, R. Rinaldi, M. Corrado, M. Cascione
Summary: This review primarily discusses the relationship between contact lens discomfort (CLD) and the surface properties of contact lenses (CLs), specifically the coefficient of friction (CoF). The review emphasizes the importance of introducing a standardized protocol for measuring CoF and calls for a more precise evaluation of the relationship between surface properties and comfort in CLs users.
COLLOIDS AND SURFACES B-BIOINTERFACES
(2024)
Article
Biophysics
Debdip Brahma, Tamal Sarkar, Rupal Kaushik, Akshay Narayan Sarangi, Amar Nath Gupta
Summary: This in-vitro study evaluates the effect of reactive oxygen species (ROS) on the structural rearrangement of elastin. The results show that oxidative stress leads to a decrease in protein size and changes in secondary structure, potentially promoting protein aggregation. This study is important for therapeutics aiming to prevent elastin degradation and aging.
COLLOIDS AND SURFACES B-BIOINTERFACES
(2024)
Article
Biophysics
Xin Yang, Qiang Wang, Chaoxi Yan, Degang Huang, Yinchang Zhang, Huazheng He, Shouliang Xiong, Congming Li, Pingbo Chen, Tingjun Ye, Dan Hu, Lei Wang
Summary: This study presents a practical and effective strategy to improve osseointegration in patients with osteoporosis. By coating titanium implants with polydopamine followed by strontium modification, the bi-functional implants promote bone regeneration and immune regulation. The results show good biocompatibility, sustained release of strontium ions, and stable osseointegration between bone tissues and implants.
COLLOIDS AND SURFACES B-BIOINTERFACES
(2024)
Article
Biophysics
Sengwang Fu, Jianping Zhu, Zhijun Jiang, Yue Cao, Yufei Chen, Lihao Zhang, Sunlong Li, Weipeng Lu, Chengbin Miao, Qing He, Qi Li, Weixing Zhang, Lehao Ren, Yachun Li, Hongchao Shi, Cihui Liu
Summary: Effective management of biofluids is crucial for in vivo surgical interventions. Recent advances include self-sealing needles, drug-eluting stents, and shear-thinning hydrogels. However, complications associated with intestinal mucosal injury and secondary damage still persist. In this study, researchers developed an interpenetrating Janus wettability stent coating that enables unidirectional draining of excessive biofluid. They also demonstrated directional biofluid movement using a self-pumping dressing with potential applications in biofluid collection and disease diagnosis through metal ion detection. This integrated system presents an opportunity for designing wound dressings with effective biofluid management and metal ion detection capabilities.
COLLOIDS AND SURFACES B-BIOINTERFACES
(2024)
Article
Biophysics
Maryam Hassani, Mojtaba Kamankesh, Mazda Rad-Malekshahi, Kobra Rostamizadeh, Farhad Rezaee, Ismaeil Haririan, Seyed Mojtaba Daghighi
Summary: Bacterial adhesion and biofilm formation on the surface of biomaterial implants is a critical problem, and a polymer brush coating with antiadhesive and antimicrobial properties has proven to be highly effective in resolving this issue.
COLLOIDS AND SURFACES B-BIOINTERFACES
(2024)
Article
Biophysics
Huaihong Zhang, Na Liu, Yuting Zhang, Hui Cang, Zhaosheng Cai, Ziqun Huang, Jun Li
Summary: A functionalized cationic polymer, CR-PQAC, was designed and synthesized for photothermal enhanced antimicrobial therapy. The CR-PQAC nanoparticles exhibited significant antibacterial activity and low cytotoxicity against mammalian cells.
COLLOIDS AND SURFACES B-BIOINTERFACES
(2024)
Article
Biophysics
Ipsita Sahu, Priyadarshi Chakraborty
Summary: Peptide nanotechnology bridges the gap between materials and biological worlds by utilizing self-assembly of short-peptide building blocks. Hydrogels engineered from these short peptides show great potential in biomedical applications, but their weak mechanical properties and limited functional diversity need to be addressed. Nanoengineering the networks of these hydrogels by incorporating small molecules, polymers, and inorganic/carbon nanomaterials can enhance their mechanical properties and expand their functional diversity.
COLLOIDS AND SURFACES B-BIOINTERFACES
(2024)
Article
Biophysics
Hao Wei, Yajun Gu, Ao Li, Panpan Song, Dingding Liu, Feihu Sun, Xiaofeng Ma, Xiaoyun Qian
Summary: In this study, a stable three-dimensional conductive hydrogel was prepared by cross-linking MXenes to Matrigel hydrogel. The conductive hydrogel promotes the proliferation and differentiation of NSCs, providing new strategies for neural tissue engineering.
COLLOIDS AND SURFACES B-BIOINTERFACES
(2024)
Article
Biophysics
Yue Zhong, Xiaoli Ge, Juan Zhang, Qun Wei, Feng Wang, Yongke Zhong
Summary: The effect of oxygenic groups on the hemocompatibility of activated carbon was studied through liquid-phase oxidation and subsequent heat treatment. Results showed that the presence of oxygenic groups improved hemocompatibility, while their removal decreased it.
COLLOIDS AND SURFACES B-BIOINTERFACES
(2024)