Article
Polymer Science
Mohammed S. Algahtani, Mohammad Zaki Ahmad, Ihab Hamed Nourein, Hassan A. Albarqi, Hamad S. Alyami, Mohammad H. Alyami, Abdulsalam A. Alqahtani, Ali Alasiri, Thamer S. Algahtani, Abdul Aleem Mohammed, Javed Ahmad
Summary: Hydrogels are a significant drug delivery system for topical treatment of cutaneous open wounds. Incorporating curcumin into a nanoemulsion system within hydrogels has shown improved therapeutic efficacy for wound healing. This nanomedicine-based approach enhances the bioavailability of curcumin and accelerates the wound healing process.
Article
Pharmacology & Pharmacy
Asmaa O. Manaa, Hoda H. Bagjdadi, Nefertiti A. El-Nikhely, Lamia A. Heikal, Lobna S. El-Hosseiny
Summary: This study successfully developed a stable nanoemulsion of oregano essential oil (ONE) and evaluated its antibacterial and anticancer effects, finding that the nanoemulsion exhibited improved activity. Furthermore, the nanoemulsion significantly inhibited cell proliferation and induced apoptosis, as evidenced by upregulation of apoptotic markers and downregulation of proliferation markers.
JOURNAL OF DRUG DELIVERY SCIENCE AND TECHNOLOGY
(2022)
Review
Critical Care Medicine
Meera Kumari, Dhiraj Kumar Nanda
Summary: The review article focuses on the potential uses of curcumin nanoemulsion in the treatment and management of burn wounds. The poor solubility and low bioavailability of curcumin limit its effective use in managing bacterial infection related to burn wounds. The use of nano particle-based drug delivery systems, particularly nanoemulsion, can overcome these limitations and enhance the permeation ability of curcumin, making it a potential topical therapeutic agent in burn wound infection.
Article
Pharmacology & Pharmacy
Meenakshi Dudi, Raj Kumar, Priyanshi Saini, Aashima Sharma, Satish Kumar Pandey, Harjot Kaur, Ravinder Kumar, S. K. Mehta
Summary: In this study, OST-loaded oil in water nano-emulsion (OST-NEm) was prepared using a low-cost and highly effective ultrasonication emulsification method. The NEm showed good storage stability and stability under different salt concentrations and pH conditions. The cell viability studies confirmed the lack of toxicity of OST-NEm up to a concentration of 160 muM. OST and OST-NEm exhibited higher antioxidant potential compared to the control substance BHT.
JOURNAL OF DRUG DELIVERY SCIENCE AND TECHNOLOGY
(2023)
Article
Engineering, Biomedical
Rajib Dey, Riya Mukherjee, Jayanta Haldar
Summary: This report introduces an intrinsically antimicrobial hydrogel (HyDex) that exhibits broad-spectrum antimicrobial activity, hemostatic ability, and rapid wound closure efficacy. The hydrogel demonstrates effective antibacterial and antifungal effects, rapid blood clotting, and reduction in inflammatory responses in various models, showing great potential in addressing resistant bacteria, fungal infections, bleeding, and inflammation.
ADVANCED HEALTHCARE MATERIALS
(2022)
Article
Acoustics
Rania A. Hashad, Ritu Singla, Sukhvir Kaur Bhangu, Edwina Jap, Haiyan Zhu, Anton Y. Peleg, Luke Blakeway, Christoph E. Hagemeyer, Francesca Cavalieri, Muthupandian Ashokkumar, Karen Alt
Summary: In this study, a novel nanocarrier system was developed using the natural food preservative peptide Nisin. The system, called nisin-shelled nanoemulsions (NSNE), exhibited stable and uniform nanoemulsion structure with high bactericidal activity and drug loading capacity. Moreover, the nisin shell was used for the specific attachment of a cancer targeting ligand, leading to the successful assembly of targeted NSNE loaded with the chemotherapeutic drug Doxorubicin. The targeted NSNE demonstrated cancer-specific binding and enhanced cytotoxicity to HER2 expressing tumor cells.
ULTRASONICS SONOCHEMISTRY
(2022)
Article
Pharmacology & Pharmacy
Megumi Nishitani Yukuyama, Lara Mendes Ferreira Guimaraes, Rafael Scheliga Segovia, Claudiana Lameu, Gabriel Lima Barros de Araujo, Raimar Lobenberg, Aline de Souza, Mirla Anali Bazan Henostroza, Beatriz Rabelo Folchini, Camilla Midori Peroni, Mariana Yasue Saito Miyagi, Isabela Fernandes Oliveira, Jose Fernando Rinaldi Alvarenga, Jarlei Fiamoncini, Nadia Araci Bou-Chacra
Summary: Malignant wounds (MWs) in advanced stage cancer patients can cause significant deformity and malodor, affecting their quality of life. Researchers have often overlooked this disease. This study proposes a new oral treatment option using high-oil-content flubendazole (FLZ) loaded in nanoemulsion for MW. Results from in vivo tests on mice showed that FLZ-loaded nanoemulsion containing oil derived from linoleic acid had the best treatment effects for MW.
JOURNAL OF DRUG DELIVERY SCIENCE AND TECHNOLOGY
(2022)
Article
Polymer Science
Mohd Nazam Ansari, Gamal A. Soliman, Najeeb Ur Rehman, Md Khalid Anwer
Summary: The development of an effective gel for treating eczema is still a challenge in medicine. In this study, researchers developed a chitosan gel based on nanoemulsions for wound healing and evaluated its properties. The gel showed promising results in terms of drug release, wound healing, and anti-inflammatory activities.
Article
Pharmacology & Pharmacy
Touseef Nawaz, Muhammad Iqbal, Barkat Ali Khan, Naveed Ahmed, Asif Nawaz, Akhtar Rasul, Waleed Y. Rizg, Abdulmajeed M. Jali, Rayan A. Ahmed, Awaji Y. Safhi
Summary: This study investigated a pharmaceutical acriflavine-loaded polycaprolactone nanoemulsion for burn wound healing. The optimized nanoemulsion was found to be stable with desirable physicochemical properties. In vivo experiments showed that the nanoemulsion formulation had high wound healing potential.
Article
Food Science & Technology
Rupsa Roychowdhury, Nandita Srivastava, Sumeeta Kumari, Anil Kumar Pinnaka, Anirban Roy Choudhury
Summary: The study isolated a marine exopolysaccharide EPS K1(T)-9 from Neorhizobium urealyticum sp. nov. and investigated its potential as a replacement for synthetic emulsifiers. EPS K1(T)-9 exhibited pH stable emulsification activity and functional properties such as non-Newtonian pseudoplastic behavior, high water and oil holding capacity, and swelling capacity. The findings suggest that EPS K1(T)-9 has promising applications in the food and related industries.
LWT-FOOD SCIENCE AND TECHNOLOGY
(2021)
Article
Biochemistry & Molecular Biology
Idglan Sa de Lima, Maria Onaira Goncalves Ferreira, Esmeralda Maria Lustosa Barros, Marcia dos Santos Rizzo, Jailson de Araujo Santos, Alessandra Braga Ribeiro, Josy Anteveli Osajima Furtini, Edson C. Silva-Filho, Leticia M. Estevinho
Summary: Chicha gum, obtained from the Sterculia striata plant, is a natural polymer with the ability to form hydrogels due to its hydroxyl groups. These hydrogels can associate with biologically active molecules and enhance their properties for drug delivery systems. The hydrogels produced in this study, associated with nerolidol, exhibited antibacterial activity and were effective in wound healing, making them potential products for wound treatment.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2023)
Article
Biochemistry & Molecular Biology
Thi Thanh Ngoc Le, Thi Kieu Nhi Nguyen, Van Minh Nguyen, Thi Cam Minh Dao, Hoai Bao Chau Nguyen, Cong Thuan Dang, Thi Bao Chi Le, Thi Khanh Linh Nguyen, Phuong Thao Tien Nguyen, Le Hoang Nam Dang, Van Minh Doan, Hoang Nhan Ho
Summary: This study aimed to optimize a CUR-NE-based gel and evaluate its physicochemical and biological properties for the treatment of acne and wound healing. The optimal formulation contained CUR, Capryol 90 (oil), Labrasol: Cremophor RH40 (1:1) (surfactants), propylene glycol (co-surfactant), and water. The obtained CUR-NE gel showed higher in vitro release of CUR and accelerated antibacterial and wound healing activities compared to other CUR-loaded gels.
Review
Pharmacology & Pharmacy
Paolo Pino, Francesca Bosco, Chiara Mollea, Barbara Onida
Summary: Chronic wounds are a global health concern, with increasing incidence due to age and age-related comorbidities. Antimicrobial bionanocomposites, such as nano-ZnO-BNC, offer promising solutions for wound healing with their antimicrobial properties. However, standardized testing procedures and a comprehensive understanding of their antimicrobial mechanism are still lacking.
Article
Agricultural Engineering
Sang-Il Han, Min Seo Jeon, Joon-Woo Ahn, Yoon-E Choi
Summary: This study used ultrasonication at a frequency of 40 kHz to enhance the growth of Haematococcus lacustris and identified the optimal conditions as 20 W of ultrasound output and a 15-day treatment interval. The results showed that under the optimal conditions, the cell density and chlorophyll content increased by 50.00% and 39.01%, respectively. Transmission electron microscopy analysis revealed that ultrasonication caused minimal damage to the cell layers of H. lacustris.
BIORESOURCE TECHNOLOGY
(2022)
Review
Infectious Diseases
Ali Pormohammad, Nadia K. Monych, Sougata Ghosh, Diana L. Turner, Raymond J. Turner
Summary: Wounds continue to be a serious medical concern, with infectious microbes in biofilm form delaying the healing process. Developing novel wound dressing drug formulations and materials with combined antibacterial, antibiofilm, and wound healing properties are necessary. Nanomaterials show promising applicability for various wound types with their unique properties.
Article
Materials Science, Biomaterials
Karuppusamy Shanmugapriya, Hyejin Kim, Hyun Wook Kang
Summary: In this study, an EGFR-conjugated hydrogel was fabricated to promote wound healing in cold restraint-induced gastric ulceration on burn wounds, demonstrating good biocompatibility and enhanced healing ability. In vivo experiments showed that EGFR-H had stronger ulcer healing ability compared to hydrogel alone and controls.
MATERIALS SCIENCE AND ENGINEERING C-MATERIALS FOR BIOLOGICAL APPLICATIONS
(2021)
Article
Food Science & Technology
Viruja Ummat, Saravana Periaswamy Sivagnanam, Gaurav Rajauria, Colm O'Donnell, Brijesh Kumar Tiwari
Summary: Various methods and technologies for extracting bioactive compounds from seaweeds are crucial for improving extraction efficiency. Combinations of different cell disruption technologies and extraction methods can enhance the purity and quantity of target compounds, contributing to improved process efficiency.
TRENDS IN FOOD SCIENCE & TECHNOLOGY
(2021)
Article
Biochemistry & Molecular Biology
Ming Zhao, Marco Garcia-Vaquero, Joanna Przyborska, Saravana Periaswamy Sivagnanam, Brijesh Tiwari
Summary: Analytical methods for determining the purity of extracted fucoidan from brown seaweeds were developed and compared, with FT-IR spectroscopy and chemometrics showing potential for non-destructive and real-time determination. The results suggested that these methods could be effective for assessing fucoidan purity.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2021)
Article
Pharmacology & Pharmacy
Karuppusamy Shanmugapriya, Subramanian Palanisamy, Pandi Boomi, Rathinasamy Subaskumar, Sundaram Ravikumar, Thangavelu Thayumanavan
Summary: This study successfully synthesized silver nanoparticles using Indian Gnaphalium polycaulon plant extract, demonstrating excellent antimicrobial activity, especially against Gram-positive, Gram-negative bacteria, and fungal pathogens. Additionally, the nanoparticles showed significant efficacy in promoting wound healing.
JOURNAL OF DRUG DELIVERY SCIENCE AND TECHNOLOGY
(2021)
Article
Education, Scientific Disciplines
Karuppusamy Shanmugapriya, Periaswamy Sivagnanam Saravana, Rajakumari Karuppusamy, Thangavelu Thayumanavan
Summary: The study identified bioactive metabolites from G. polycaulon extracts and found that these compounds interacted with specific proteins. The similarity toolbox provided a convenient way to find plant phytoconstituents with similar ligands. G. polycaulon plant has the potential for wound healing and could be used for novel drug discovery.
INDIAN JOURNAL OF PHARMACEUTICAL EDUCATION AND RESEARCH
(2021)
Article
Biophysics
Karuppusamy Shanmugapriya, Hyun Wook Kang
Summary: The synthesized nanohydroxyapatite/collagen-loaded fucoidan-based nanomaterial is non-toxic, promotes cell proliferation and migration, and inhibits reactive oxygen species in gastrointestinal cancer cells. These findings suggest its potential as a carrier for targeted drug delivery.
COLLOIDS AND SURFACES B-BIOINTERFACES
(2021)
Article
Biochemistry & Molecular Biology
Eduarda M. Cabral, Julie Rose Mae Mondala, Marcia Oliveira, Joanna Przyborska, Stephen Fitzpatrick, Dilip K. Rai, Saravana Periaswamy Sivagnanam, Marco Garcia-Vaquero, Denis O'Shea, Michael Devereux, Brijesh K. Tiwari, James Curtin
Summary: The study investigated the antimicrobial and anticancer properties of a fucoidan extract and fractions from Fucus vesiculosus. The fractions showed inhibitory effects on the growth of various bacteria, and the 300 kDa fraction displayed low IC50 values against brain glioblastoma cancer cells. Further research is needed to explore the mechanisms of action.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2021)
Review
Biotechnology & Applied Microbiology
Periaswamy Sivagnanam Saravana, Viruja Ummat, Paula Bourke, Brijesh K. Tiwari
Summary: This review discusses the use of novel cell disruption techniques for the extraction of valuable compounds from macro-microalgae. These techniques, such as ionic liquid and deep eutectic solvent, offer advantages of green chemistry and sustainability, including shorter extraction time, improved yield, and reduced cost.
CRITICAL REVIEWS IN BIOTECHNOLOGY
(2023)
Review
Chemistry, Medicinal
Shanmugapriya Karuppusamy, Gaurav Rajauria, Stephen Fitzpatrick, Henry Lyons, Helena McMahon, James Curtin, Brijesh K. Tiwari, Colm O'Donnell
Summary: Marine algal species, especially brown algae, contain polysaccharides such as laminarin that have potential pharmacological properties and health benefits. Laminarin has been extensively studied for its antioxidant, anti-tumor, anti-coagulant, anticancer, immunomodulatory, anti-obesity, anti-diabetic, anti-inflammatory, wound healing, and neuroprotective potential. It is considered a biodegradable, biocompatible, and low toxic substance, making it a promising material for biomedical and industrial applications. This review provides an overview of the biological activities, mechanisms of action, impacts on human health, and reported health benefits of laminarin, as well as recent advances and opportunities for further research in this field.
Article
Chemistry, Medicinal
Dimitra Graikini, Arturo B. Soro, Saravana P. Sivagnanam, Brijesh K. Tiwari, Lourdes Sanchez
Summary: This study investigated the bioactivity of extracts from brown algae Fucus vesiculosus against rotavirus and foodborne bacteria, and found that these extracts can neutralize and inhibit the growth of these microorganisms.
Article
Biotechnology & Applied Microbiology
Xianglu Zhu, Laura Healy, Janith Wanigasekara, Ming Zhao, Ramesh Babu Padamati, Shanmugapriya Karuppusamy, James F. Curtin, Saravana Periaswamy Sivagnanam, Dilip K. Rai, Da-Wen Sun, Brijesh K. Tiwari
Summary: The present study focused on the extraction and characterization of laminarin from Laminaria digitata. Optimized extraction conditions were achieved through central composite design and ultrasound technology, resulting in high yield and purity of the laminarin extracts. These extracts exhibited significant antioxidant and cytotoxic activities, effectively inducing cancer cell death.
ALGAL RESEARCH-BIOMASS BIOFUELS AND BIOPRODUCTS
(2023)
Article
Biotechnology & Applied Microbiology
Xianglu Zhu, Laura Healy, Rahel Suchintita Das, M. L. Bhavya, Shanmugapriya Karuppusamy, Da-Wen Sun, Colm O'Donnell, Brijesh K. Tiwari
Summary: This paper investigates a novel biorefinery process using hydrodynamic cavitation (HDC) for the extraction of valuable compounds from brown seaweed. By controlling processing time, solvent selection, and HDC conditions, a cascading extraction of multiple valuable compounds was achieved. The results demonstrate that this process can significantly reduce energy consumption, and the extracted laminarin exhibits identical bioactive activities.
ALGAL RESEARCH-BIOMASS BIOFUELS AND BIOPRODUCTS
(2023)
Article
Chemistry, Applied
Saravana Periaswamy Sivagnanam, Hadil Alaydi, Eduarda M. Cabral, Mahesha M. Poojary, Shanmugapriya Karuppusamy, Brijesh K. Tiwari
Summary: This study investigated the valorization of the invasive macroalgae Ascophyllum nodosum by exploring the extraction of multiple products using ultrasound, microwave, and supercritical CO2 techniques. The results showed that using ethanol as the extraction solvent improved the yields and antioxidant activity. Furthermore, pretreatment with ultrasound and microwave enhanced the yield of carotenoids, total phenolics, and fatty acids in the extracts.
Article
Biophysics
Cristina Potrich, Anna Pedrotti, Cecilia Pederzolli, Lorenzo Lunelli
Summary: This study developed different functional surfaces for capturing exosomes and verified their effectiveness through experiments. Among them, the negatively-charged surface performed the best, capturing a large number of exosomes and successfully analyzing their biomarkers.
COLLOIDS AND SURFACES B-BIOINTERFACES
(2024)
Article
Biophysics
Brojendra Nath Saren, Srushti Mahajan, Mayur Aalhate, Rahul Kumar, Essha Chatterjee, Indrani Maji, Ujala Gupta, Santosh Kumar Guru, Pankaj Kumar Singh
Summary: This study developed P-selectin-targeted dasatinib nanoparticles coated with chitosan and fucoidan (DST-CH-FUC-NPs), which showed sustained release, reduced hemolytic potential, increased cytotoxicity and cellular uptake compared to free dasatinib. These nanoparticles also demonstrated enhanced ROS production, mitochondrial membrane potential damage, apoptosis induction, cell migration inhibition, and disruption of lysosomal membrane integrity.
COLLOIDS AND SURFACES B-BIOINTERFACES
(2024)
Article
Biophysics
Weiping Deng, Xiaohui Li, Ya Li, Zhongbing Huang, Yulin Wang, Ning Mu, Juan Wang, Tunan Chen, Ximing Pu, Guangfu Yin, Hua Feng
Summary: This study demonstrates the importance of chirality in nerve repair by constructing a GO-phenylalanine derivative hydrogel system. In vivo experiments show that the dextro group significantly improves functional recovery and histological restoration in rat sciatic nerve repair models. The doped GO promotes angiogenesis and myelination. These results suggest that chirality plays a crucial role in promoting nerve regeneration.
COLLOIDS AND SURFACES B-BIOINTERFACES
(2024)
Article
Biophysics
Xiaoyan Wang, Jin Gao, Yu Gao, Linlin Zhang, Congchao Xu, Qintong Li, Lin Li, Jianliang Xue
Summary: In this study, a highly effective surfactant producer strain, Bacillus Cereus GX7, was isolated from the oil tank bottom sludge of Shengli Oil Field in China. The biosurfactant produced by GX7 was identified as surfactin, a lipopeptide surfactant, through TLC, FT-IR, and LC-MS/MS analysis. The fermentation process of GX7 was optimized using single-factor experiments, focusing on the composition of fermentation medium and fermentation conditions. Glucose and peptone were found to be the best carbon and nitrogen sources, and the optimum temperature, inoculum amount, pH, rotation speed, and fermentation time for the strain were determined to be 30°C, 1%, 7.5, 150 rpm, and 48 h, respectively. After optimization, the surface tension and emulsification index of the fermentation broth were 26.84 mN/m and 57.84%, respectively. Furthermore, the biosurfactant produced by GX7 demonstrated good stability over a wide range of temperature, pH, and salt concentration.
COLLOIDS AND SURFACES B-BIOINTERFACES
(2024)
Article
Biophysics
Rodney Marcelo do Nascimento, Christine Grauby-Heywang, Houssem Kahli, Nesrine Debez, Laure Beven, Ivan Helmuth Bechtold, Touria Cohen Bouhacina
Summary: This article presents a theoretical model based on thermodynamic rules to assess the early stages of bacterial biofilm formation on different material surfaces. By utilizing morphological characteristics of bacteria and Atomic Force Microscopy images, the model generates a dataset of energetically minimized states, which can be correlated with bacterial adhesion states.
COLLOIDS AND SURFACES B-BIOINTERFACES
(2024)
Article
Biophysics
Filipa A. L. S. Silva, Licinia Timochenco, Raquel Costa-Almeida, Jose Ramiro Fernandes, Susana G. Santos, Fernao D. Magalhaes, Artur M. Pinto
Summary: The study demonstrates that by photoreducing nanosized graphene oxide using ultraviolet radiation, nanometric particles with high light-to-heat conversion efficiency and water stability can be obtained. These nanomaterials exhibit high absorption in the near-infrared region and show no cytotoxicity towards human cells, indicating their potential for safe therapy.
COLLOIDS AND SURFACES B-BIOINTERFACES
(2024)
Article
Biophysics
D. Costa, V. De Matteis, F. Treso, G. Montani, M. Martino, R. Rinaldi, M. Corrado, M. Cascione
Summary: This review primarily discusses the relationship between contact lens discomfort (CLD) and the surface properties of contact lenses (CLs), specifically the coefficient of friction (CoF). The review emphasizes the importance of introducing a standardized protocol for measuring CoF and calls for a more precise evaluation of the relationship between surface properties and comfort in CLs users.
COLLOIDS AND SURFACES B-BIOINTERFACES
(2024)
Article
Biophysics
Debdip Brahma, Tamal Sarkar, Rupal Kaushik, Akshay Narayan Sarangi, Amar Nath Gupta
Summary: This in-vitro study evaluates the effect of reactive oxygen species (ROS) on the structural rearrangement of elastin. The results show that oxidative stress leads to a decrease in protein size and changes in secondary structure, potentially promoting protein aggregation. This study is important for therapeutics aiming to prevent elastin degradation and aging.
COLLOIDS AND SURFACES B-BIOINTERFACES
(2024)
Article
Biophysics
Xin Yang, Qiang Wang, Chaoxi Yan, Degang Huang, Yinchang Zhang, Huazheng He, Shouliang Xiong, Congming Li, Pingbo Chen, Tingjun Ye, Dan Hu, Lei Wang
Summary: This study presents a practical and effective strategy to improve osseointegration in patients with osteoporosis. By coating titanium implants with polydopamine followed by strontium modification, the bi-functional implants promote bone regeneration and immune regulation. The results show good biocompatibility, sustained release of strontium ions, and stable osseointegration between bone tissues and implants.
COLLOIDS AND SURFACES B-BIOINTERFACES
(2024)
Article
Biophysics
Sengwang Fu, Jianping Zhu, Zhijun Jiang, Yue Cao, Yufei Chen, Lihao Zhang, Sunlong Li, Weipeng Lu, Chengbin Miao, Qing He, Qi Li, Weixing Zhang, Lehao Ren, Yachun Li, Hongchao Shi, Cihui Liu
Summary: Effective management of biofluids is crucial for in vivo surgical interventions. Recent advances include self-sealing needles, drug-eluting stents, and shear-thinning hydrogels. However, complications associated with intestinal mucosal injury and secondary damage still persist. In this study, researchers developed an interpenetrating Janus wettability stent coating that enables unidirectional draining of excessive biofluid. They also demonstrated directional biofluid movement using a self-pumping dressing with potential applications in biofluid collection and disease diagnosis through metal ion detection. This integrated system presents an opportunity for designing wound dressings with effective biofluid management and metal ion detection capabilities.
COLLOIDS AND SURFACES B-BIOINTERFACES
(2024)
Article
Biophysics
Maryam Hassani, Mojtaba Kamankesh, Mazda Rad-Malekshahi, Kobra Rostamizadeh, Farhad Rezaee, Ismaeil Haririan, Seyed Mojtaba Daghighi
Summary: Bacterial adhesion and biofilm formation on the surface of biomaterial implants is a critical problem, and a polymer brush coating with antiadhesive and antimicrobial properties has proven to be highly effective in resolving this issue.
COLLOIDS AND SURFACES B-BIOINTERFACES
(2024)
Article
Biophysics
Huaihong Zhang, Na Liu, Yuting Zhang, Hui Cang, Zhaosheng Cai, Ziqun Huang, Jun Li
Summary: A functionalized cationic polymer, CR-PQAC, was designed and synthesized for photothermal enhanced antimicrobial therapy. The CR-PQAC nanoparticles exhibited significant antibacterial activity and low cytotoxicity against mammalian cells.
COLLOIDS AND SURFACES B-BIOINTERFACES
(2024)
Article
Biophysics
Ipsita Sahu, Priyadarshi Chakraborty
Summary: Peptide nanotechnology bridges the gap between materials and biological worlds by utilizing self-assembly of short-peptide building blocks. Hydrogels engineered from these short peptides show great potential in biomedical applications, but their weak mechanical properties and limited functional diversity need to be addressed. Nanoengineering the networks of these hydrogels by incorporating small molecules, polymers, and inorganic/carbon nanomaterials can enhance their mechanical properties and expand their functional diversity.
COLLOIDS AND SURFACES B-BIOINTERFACES
(2024)
Article
Biophysics
Hao Wei, Yajun Gu, Ao Li, Panpan Song, Dingding Liu, Feihu Sun, Xiaofeng Ma, Xiaoyun Qian
Summary: In this study, a stable three-dimensional conductive hydrogel was prepared by cross-linking MXenes to Matrigel hydrogel. The conductive hydrogel promotes the proliferation and differentiation of NSCs, providing new strategies for neural tissue engineering.
COLLOIDS AND SURFACES B-BIOINTERFACES
(2024)
Article
Biophysics
Yue Zhong, Xiaoli Ge, Juan Zhang, Qun Wei, Feng Wang, Yongke Zhong
Summary: The effect of oxygenic groups on the hemocompatibility of activated carbon was studied through liquid-phase oxidation and subsequent heat treatment. Results showed that the presence of oxygenic groups improved hemocompatibility, while their removal decreased it.
COLLOIDS AND SURFACES B-BIOINTERFACES
(2024)
