Article
Biochemistry & Molecular Biology
Fen Ma, Chenguang Jiang, Wenyuan Xie, Defeng Wu
Summary: Using polysaccharide nanocrystals, such as chitin nanocrystals, as nanofillers for biodegradable aliphatic polymers is an attractive method for developing fully degradable nanocomposites. The incorporation of chitin nanocrystals in poly(L-lactide)/poly(D-lactide) blends promotes the formation of stereocomplex crystallites and accelerates overall crystallization kinetics. The nanocomposites exhibit higher stereocomplex crystallization temperatures and lower activation energy compared to the blend. However, the presence of chitin nanocrystals reduces the fraction of stereocomplex crystallites due to the nucleation effect, despite an increased rate of homocrystallization. This study provides valuable information for the use of chitin nanocrystals as nucleators for polylactide stereocomplexes.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2023)
Article
Chemistry, Multidisciplinary
Rami Hador, Michael Shuster, Vincenzo Venditto, Moshe Kol
Summary: This study proposes a new approach to tolerate stereoerrors in the polymer by crowding them in a stereogradient copolymer. A zirconium complex of an amine tris(phenolate) ligand is used as a catalyst for the ring opening polymerization of meso-lactide at room temperature, and stereogradient copolymers are formed in the polymerization of mixtures of meso-lactide/L-lactide at 180 degrees C. These stereogradient copolymers exhibit enhanced crystallinities compared to stereorandom copolymers obtained with tin octanoate.
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
(2022)
Article
Polymer Science
Lidong Feng, Xinchao Bian, Gao Li, Xuesi Chen
Summary: The study shows that the compatibility between PLLA and PLDLA-m decreases as the L-lactate unit content in PLDLA-m decreases, impacting the crystallization and compatibility of the blends.
Article
Polymer Science
Lidong Feng, Xinchao Bian, Gao Li, Xuesi Chen
Summary: By investigating the thermal properties, morphology, and thermal stability of PLLA/PDLA blends, a new stereoamorphous mesophase (sam-PLA) structure was discovered, and the relationship between different phases in the PLLA/PDLA blends was explored.
Article
Chemistry, Physical
Andrea Atrei, Beata Lesiak-Orlowska, Jozsef Toth
Summary: The surface composition of magnetite nanoparticles, bare and functionalized with citrate, was investigated using XPS and ToF-SIMS. The results showed that the oxide composition was not modified by the citrate functionalization. The amount of citrate ions adsorbed on the surface was independent of the functionalization procedure. The citrate shell was found to be a single layer that only partially covered the nanoparticle surface. Additionally, the presence of ammonia molecules from the Fe(II) salt used in the nanoparticle preparation was detected.
APPLIED SURFACE SCIENCE
(2022)
Article
Chemistry, Physical
Sk Shamim Hasan Abir, Julio E. Trevino, Bhupendra B. Srivastava, Muhtasim Ul Karim Sadaf, Julia I. Salas, Karen Lozano, Mohammed Jasim Uddin
Summary: In recent years, there has been great potential in the optoelectronic and flexible nanogenerator applications of inorganic perovskite materials. This study successfully synthesized inorganic perovskite nanocrystals with blue to green tunable photoluminescence and fabricated flexible piezoelectric nanogenerators. The experiments demonstrated that the green perovskite nanocrystals had higher voltage and current outputs compared to the blue perovskite nanocrystals.
Article
Polymer Science
Prasong Srihanam, Wiriya Thongsomboon, Yodthong Baimark
Summary: The aim of this study was to modify PLLA-b-PEG-b-PLLA copolymer using low-cost CaCO3 filler to improve its material properties. The addition of CaCO3 enhanced the crystallinity and thermal stability of PLLA-b-PEG-b-PLLA matrix. SEM analysis showed stronger interfacial adhesion between PLLA-b-PEG-b-PLLA and CaCO3 compared to PLLA and CaCO3. Tensile testing revealed increased stress and modulus for PLLA-b-PEG-b-PLLA matrix with CaCO3, while these properties significantly decreased for PLLA matrix. Therefore, CaCO3 shows promise as an inexpensive filler for improving PLLA-b-PEG-b-PLLA bioplastics.
Article
Chemistry, Applied
Yaowalak Srisuwan, Yodthong Baimark
Summary: This paper reports a study on flexible polymer blends made from PLLA-PEG-PLLA and TPS. The addition of TPS suppressed crystallizability of PLLA and PLLA-PEG-PLLA matrices, while greatly increasing the thermal stability of PLLA-PEG-PLLA. The PEG middle-blocks enhanced phase compatibility between PLLA-PEG-PLLA and TPS, resulting in ductile and flexible blend films.
CARBOHYDRATE POLYMERS
(2022)
Article
Polymer Science
Lei Hua, Xiaodong Wang
Summary: New biodegradable aliphatic PLLA-PBA-PLLA copolymers with different PLLA block lengths showed different structures and crystallization behaviors of PBA-mid, which were studied using various analytical techniques.
Article
Polymer Science
Yuhan Wei, Zhengyue Wang, Shuaining Zhou, Zhibo Li
Summary: A tough and transparent film of poly(L-lactic acid)/poly(D-lactide)-b-poly(butadiene)-b-poly(D-lactide) (PLLA/PDLA-PB-PDLA) with balanced strength was obtained. The film was achieved by synthesizing PDLA-PB-PDLA triblock copolymer using ring-opening polymerization and then blending it with PLLA. The blended films exhibited good transparency even with a high loading of PDLA-PB-PDLA. The enhanced mechanical properties were attributed to the synergistic effect of flexible PB chains and stereocomplex crystals formed between PLLA matrix and PDLA chains.
Article
Polymer Science
Zirui Huang, Meiling Zhong, Haibo Yang, Enqin Xu, Dehui Ji, Paul Joseph, Ri-Chao Zhang
Summary: The isothermal crystallization of poly(l-lactide) was studied using in-situ wide angle X-ray diffraction and polarized optical microscopes equipped with a hot-stage accessory. It was found that PLLA formed spherulites at high temperature and exhibited irregular morphology at low temperature, attributed to varying crystallization rates. The change in the Avrami exponent value with temperature further supported the different trend in crystal morphology.
Article
Biochemistry & Molecular Biology
Pejman Ghaffari-Bohlouli, Hafez Jafari, Alireza Khatibi, Mamak Bakhtiari, Beeta Tavana, Payam Zahedi, Amin Shavandi
Summary: By reinforcing electrospun PLDLLA/PVA nanofibers with PCCNWs, the hydrophilicity, degradation rate, and mechanical properties of the composite material were enhanced, promoting cellular activity and showing potential for bone tissue engineering applications.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2021)
Article
Polymer Science
Yaowalak Srisuwan, Yodthong Baimark
Summary: In this study, high-molecular-weight poly(L-lactide)-b-poly(ethylene glycol)-b-poly(L-lactide) triblock copolymer (PLLA-PEG-PLLA) was used as a biodegradable bioplastic. However, its high cost and poor thermal stability limited its applications. Native cassava starch was blended to reduce the production cost and improve the thermal stability. The interaction between starch and PEG increased the thermal stability and phase adhesion, resulting in flexible and hydrophilic films with potential applications in biomedical, packaging, and agricultural fields.
Article
Polymer Science
M. Margarida Cardoso, Ines N. Peca, Telma Lopes, Rui Gardner, A. Bicho
Summary: DWNPs were produced with PLGA and PLLA containing doxorubicin as a model drug. Optical and fluorescence microscopy were used to examine the inner morphology and drug distribution of the double-walled microparticles. The study showed that the double-walled nanoparticles exhibited sustained drug release and the PLLA layer acted as a rate control barrier.
Article
Polymer Science
Suyang Dai, Ni Jiang, Zhenbo Ning, Zhihua Gan
Summary: The length of the PDLA block was found to have a significant impact on the degradation behavior of PLLA/4-DL-D blend films.
POLYMER INTERNATIONAL
(2021)
Article
Chemistry, Multidisciplinary
Sungwook Park, Hojun Kim, Kyungmin Woo, Jeong-Min Kim, Hye-Jun Jo, Youngdo Jeong, Kwan Hyi Lee
Summary: Researchers developed a biosensor based on the virus receptor to detect SARS-CoV-2 efficiently and sensitively, which may serve as an effective strategy for screening infectious diseases to prevent pandemics.
Article
Chemistry, Multidisciplinary
Jangsun Hwang, Youngmin Seo, Daun Jeong, Xiaoyu Ning, Christian Wiraja, Lixia Yang, Chew Teng Tan, Jinhyuck Lee, Yesol Kim, Ji Won Kim, Dai Hyun Kim, Jonghoon Choi, Chin Yan Lim, Kanyi Pu, Woo Young Jang, Chenjie Xu
Summary: This article discusses the development and application of mRNA nanosensors for wound management, which can accurately assess wound status and track the healing process in real time.
Article
Nanoscience & Nanotechnology
Phornsawat Baipaywad, Seong Vin Hong, Jong Bae Kim, Jangsun Hwang, Jonghoon Choi, Hansoo Park, Taejong Paik
Summary: A one-step, room-temperature synthesis method for fluorescent organosilica nanobeads (FOS NBs) was developed with good colloidal stability in aqueous media. This approach shows promise for large-scale production of luminescent colloidal nanobeads.
Correction
Engineering, Biomedical
Youngmin Seo, Saeromi Kim, Hyun Soo Lee, Jaeho Park, Kyungwoo Lee, Indong Jun, Hyunseon Seo, Young Jin Kim, Youngsik Yoo, Byoung Chan Choi, Hyun-Kwang Seok, Yu-Chan Kim, Myoung-Ryul Ok, Jonghoon Choi, Choun-Ki Joo, Hojeong Jeon
ACTA BIOMATERIALIA
(2022)
Article
Pharmacology & Pharmacy
Yonghyun Choi, Wooic Son, Youngpin Han, Jayoung Chae, Chul-Su Yang, Jonghoon Choi
Summary: The interaction between tumour cells and macrophages allows cancer cells to escape immune detection and clearance by interfering with macrophage phagocytosis. This study demonstrates the potential of targeting a specific glycan on CD24 to inhibit immune checkpoint. Sambucus nigra agglutinin (SNA), a sialic acid-binding lectin, was used to block CD24 and enhance phagocytosis in melanoma tumours. Additionally, SNA-conjugated hollow gold-iron oxide nanoparticles were prepared for photothermal therapy of tumours, and the combination treatment successfully increased tumour cell phagocytosis in vitro and in vivo models.
ACTA PHARMACEUTICA SINICA B
(2023)
Article
Engineering, Environmental
Changjoon Keum, Sungwook Park, Hyunro Kim, Hojun Kim, Kwan Hyi Lee, Youngdo Jeong
Summary: A modular conductive MOF (c-MOF)-gated FET biosensor array is able to discriminate small-molecular neurotransmitters in biofluids. The adsorption and oxidation of analytes inside c-MOF films enable sensitive detection of small molecules at clinically relevant concentrations, regardless of the ionic strength of the media. The hierarchical screening ability of c-MOF allows differentiated adsorption of small molecules, providing discriminatory information of each neurotransmitter.
CHEMICAL ENGINEERING JOURNAL
(2023)
Review
Biotechnology & Applied Microbiology
Sungjun Lee, Yonghyun Choi, Eunseo Jeong, Jongjun Park, Jiwon Kim, Masayoshi Tanaka, Jonghoon Choi
Summary: For the past 200 years, lactate has been misunderstood as a metabolic waste end product causing fatigue. However, recent studies have shown that lactate production is closely related to energy metabolism and has various physiological effects in different organs, such as the brain, muscles, and liver. Lactate has also been found to be a potential biomarker for fat oxidation and could be used as a preventive agent for brain diseases. Therefore, the perception of lactate as a fatigue-inducing waste product should be revised.
JOURNAL OF BIOSCIENCE AND BIOENGINEERING
(2023)
Article
Chemistry, Physical
Joohye Hong, Semi Yoon, Yonghyun Choi, Eun-Ae Chu, Kyeong Sik Jin, Hee-Young Lee, Jonghoon Choi
Summary: This study focused on the addition of cholesterol and polymers to the phospholipid envelope of liposomes to increase their rigidity, which affected the sustained release of encapsulated drugs. By controlling the cholesterol and polymer content in the phospholipid envelope, the release rate of oxygen molecules and the size of the nanoliposomes were successfully regulated. The oxygen-dissolved nanoliposomes exhibited low cytotoxicity and tunable phospholipid envelope components, showing significant potential as controlled-release carriers of oxygen.
JOURNAL OF MOLECULAR LIQUIDS
(2023)
Article
Chemistry, Multidisciplinary
Eunseo Jeong, Jongjun Park, Hayoung Kim, Sungjun Lee, Yonghyun Choi, Masayoshi Tanaka, Jonghoon Choi
Summary: This study developed a new cervical cancer diagnostic method using gold nanorods and liquid cytology to improve accuracy and reduce dependence on experts.
KOREAN JOURNAL OF CHEMICAL ENGINEERING
(2023)
Article
Chemistry, Medicinal
Jiwon Kim, Yonghyun Choi, Jongjun Park, Jonghoon Choi
Summary: Copper nanoparticles on graphene oxide nanosheets were used as antibacterial materials to combat wound-infecting bacteria. To reduce cytotoxicity, the GO/Cu was encapsulated with a gelatin complex. Gallic acid was used to stabilize the gelatin complex and showed enhanced antibacterial and antibiofilm effects compared to GO/Cu alone. The microcomplex also exhibited low cytotoxicity and biocompatibility.
ACS INFECTIOUS DISEASES
(2023)
Article
Engineering, Biomedical
Nina Tomic, Tamara Matic, Nenad Filipovic, Dragana Mitic Culafic, Aldo R. Boccacccini, Magdalena M. Stevanovic
Summary: Recent studies have shown that resveratrol, a polyphenolic compound, has various beneficial effects on human health including cardioprotection, neuroprotection, anti-cancer, anti-inflammatory, osteoinductive, and antimicrobial effects. However, its poor water solubility, sensitivity to oxygen, light, heat, rapid metabolism, and low bioavailability limit its potential for in vivo applications. The synthesis of resveratrol in nanoparticle form could be a possible solution to overcome these limitations.
JOURNAL OF BIOMATERIALS APPLICATIONS
(2023)
Review
Chemistry, Multidisciplinary
Kevin Kent Vincent Canlas, Joohye Hong, Jayoung Chae, Hyun Wook Seo, Shin Hyuk Kang, Jonghoon Choi, Hansoo Park
Summary: Viral diseases are a significant health concern, from diseases like polio that have been eradicated, to ongoing issues like HIV, and now the global threat of COVID-19. Pathogenic viruses easily spread through various means, such as contaminated food and water, bodily fluids, and even airborne particles due to their small size. Additionally, viruses have virulent proteins in their coats that allow them to assimilate into target cells. Nanoparticles have shown promise as a treatment due to their ability to target viruses at a molecular level. This review focuses on the progress in nanoparticle technology for viral therapeutics, including strategies and current clinical applications.
KOREAN JOURNAL OF CHEMICAL ENGINEERING
(2023)
Article
Chemistry, Multidisciplinary
Joohye Hong, Yonghyun Choi, Gahyun Lee, Jiwon Kim, Yeonwoo Jang, Cheol-Hee Yoon, Hyun Wook Seo, In-Kyu Park, Shin Hyuk Kang, Jonghoon Choi
Summary: A drug delivery system has been developed to effectively deliver HDAC inhibitors to latent HIV-infected cells. This system utilizes oxygen-containing nanosomes as drug carriers, which improve chemotherapy efficiency and have unique advantages for drug delivery. Enhanced targeting capability is achieved through the introduction of CXCR4 binding peptides to specifically target CD4(+) T cells, reducing drug toxicity and controlling drug release.
Article
Chemistry, Multidisciplinary
Jayoung Chae, Seung Hyun Kang, Jiwon Kim, Yonghyun Choi, Shin Hyuk Kang, Jonghoon Choi
Summary: This study successfully synthesized rifampicin-loaded mannose surface-modified solid lipid nanoparticles (Man-RIF SLNs), which exhibited antibacterial and anti-biofilm properties against non-tuberculous lung disease. Thus, mannose receptor-targeted rifampicin delivery through solid lipid nanoparticles can effectively be applied to the treatment of non-tuberculous lung disease.
NANOSCALE ADVANCES
(2023)
Review
Chemistry, Multidisciplinary
Muhammad Saad Khan, Sila Appak Baskoy, Celina Yang, Joohye Hong, Jayoung Chae, Heejin Ha, Sungjun Lee, Masayoshi Tanaka, Yonghyun Choi, Jonghoon Choi
Summary: The solubility and administration route of bioactive molecules have a significant impact on their effects. Effective and stable delivery of therapeutics is crucial for utilizing drugs in the biological and pharmacological industries. Lipid nanoparticles (LNPs) have shown potential as carriers for therapeutics and have been widely studied in clinical trials, including doxorubicin-loaded liposomes (Doxil (R)). LNPs, such as liposomes, solid lipid nanoparticles (SLNs), and nanostructured lipid nanoparticles, have also been developed for vaccine delivery. This review focuses on the use of LNPs in vaccine development and the clinical application of mRNA therapeutic-loaded LNPs.
NANOSCALE ADVANCES
(2023)
Article
Biophysics
Cristina Potrich, Anna Pedrotti, Cecilia Pederzolli, Lorenzo Lunelli
Summary: This study developed different functional surfaces for capturing exosomes and verified their effectiveness through experiments. Among them, the negatively-charged surface performed the best, capturing a large number of exosomes and successfully analyzing their biomarkers.
COLLOIDS AND SURFACES B-BIOINTERFACES
(2024)
Article
Biophysics
Brojendra Nath Saren, Srushti Mahajan, Mayur Aalhate, Rahul Kumar, Essha Chatterjee, Indrani Maji, Ujala Gupta, Santosh Kumar Guru, Pankaj Kumar Singh
Summary: This study developed P-selectin-targeted dasatinib nanoparticles coated with chitosan and fucoidan (DST-CH-FUC-NPs), which showed sustained release, reduced hemolytic potential, increased cytotoxicity and cellular uptake compared to free dasatinib. These nanoparticles also demonstrated enhanced ROS production, mitochondrial membrane potential damage, apoptosis induction, cell migration inhibition, and disruption of lysosomal membrane integrity.
COLLOIDS AND SURFACES B-BIOINTERFACES
(2024)
Article
Biophysics
Weiping Deng, Xiaohui Li, Ya Li, Zhongbing Huang, Yulin Wang, Ning Mu, Juan Wang, Tunan Chen, Ximing Pu, Guangfu Yin, Hua Feng
Summary: This study demonstrates the importance of chirality in nerve repair by constructing a GO-phenylalanine derivative hydrogel system. In vivo experiments show that the dextro group significantly improves functional recovery and histological restoration in rat sciatic nerve repair models. The doped GO promotes angiogenesis and myelination. These results suggest that chirality plays a crucial role in promoting nerve regeneration.
COLLOIDS AND SURFACES B-BIOINTERFACES
(2024)
Article
Biophysics
Xiaoyan Wang, Jin Gao, Yu Gao, Linlin Zhang, Congchao Xu, Qintong Li, Lin Li, Jianliang Xue
Summary: In this study, a highly effective surfactant producer strain, Bacillus Cereus GX7, was isolated from the oil tank bottom sludge of Shengli Oil Field in China. The biosurfactant produced by GX7 was identified as surfactin, a lipopeptide surfactant, through TLC, FT-IR, and LC-MS/MS analysis. The fermentation process of GX7 was optimized using single-factor experiments, focusing on the composition of fermentation medium and fermentation conditions. Glucose and peptone were found to be the best carbon and nitrogen sources, and the optimum temperature, inoculum amount, pH, rotation speed, and fermentation time for the strain were determined to be 30°C, 1%, 7.5, 150 rpm, and 48 h, respectively. After optimization, the surface tension and emulsification index of the fermentation broth were 26.84 mN/m and 57.84%, respectively. Furthermore, the biosurfactant produced by GX7 demonstrated good stability over a wide range of temperature, pH, and salt concentration.
COLLOIDS AND SURFACES B-BIOINTERFACES
(2024)
Article
Biophysics
Rodney Marcelo do Nascimento, Christine Grauby-Heywang, Houssem Kahli, Nesrine Debez, Laure Beven, Ivan Helmuth Bechtold, Touria Cohen Bouhacina
Summary: This article presents a theoretical model based on thermodynamic rules to assess the early stages of bacterial biofilm formation on different material surfaces. By utilizing morphological characteristics of bacteria and Atomic Force Microscopy images, the model generates a dataset of energetically minimized states, which can be correlated with bacterial adhesion states.
COLLOIDS AND SURFACES B-BIOINTERFACES
(2024)
Article
Biophysics
Filipa A. L. S. Silva, Licinia Timochenco, Raquel Costa-Almeida, Jose Ramiro Fernandes, Susana G. Santos, Fernao D. Magalhaes, Artur M. Pinto
Summary: The study demonstrates that by photoreducing nanosized graphene oxide using ultraviolet radiation, nanometric particles with high light-to-heat conversion efficiency and water stability can be obtained. These nanomaterials exhibit high absorption in the near-infrared region and show no cytotoxicity towards human cells, indicating their potential for safe therapy.
COLLOIDS AND SURFACES B-BIOINTERFACES
(2024)
Article
Biophysics
D. Costa, V. De Matteis, F. Treso, G. Montani, M. Martino, R. Rinaldi, M. Corrado, M. Cascione
Summary: This review primarily discusses the relationship between contact lens discomfort (CLD) and the surface properties of contact lenses (CLs), specifically the coefficient of friction (CoF). The review emphasizes the importance of introducing a standardized protocol for measuring CoF and calls for a more precise evaluation of the relationship between surface properties and comfort in CLs users.
COLLOIDS AND SURFACES B-BIOINTERFACES
(2024)
Article
Biophysics
Debdip Brahma, Tamal Sarkar, Rupal Kaushik, Akshay Narayan Sarangi, Amar Nath Gupta
Summary: This in-vitro study evaluates the effect of reactive oxygen species (ROS) on the structural rearrangement of elastin. The results show that oxidative stress leads to a decrease in protein size and changes in secondary structure, potentially promoting protein aggregation. This study is important for therapeutics aiming to prevent elastin degradation and aging.
COLLOIDS AND SURFACES B-BIOINTERFACES
(2024)
Article
Biophysics
Xin Yang, Qiang Wang, Chaoxi Yan, Degang Huang, Yinchang Zhang, Huazheng He, Shouliang Xiong, Congming Li, Pingbo Chen, Tingjun Ye, Dan Hu, Lei Wang
Summary: This study presents a practical and effective strategy to improve osseointegration in patients with osteoporosis. By coating titanium implants with polydopamine followed by strontium modification, the bi-functional implants promote bone regeneration and immune regulation. The results show good biocompatibility, sustained release of strontium ions, and stable osseointegration between bone tissues and implants.
COLLOIDS AND SURFACES B-BIOINTERFACES
(2024)
Article
Biophysics
Sengwang Fu, Jianping Zhu, Zhijun Jiang, Yue Cao, Yufei Chen, Lihao Zhang, Sunlong Li, Weipeng Lu, Chengbin Miao, Qing He, Qi Li, Weixing Zhang, Lehao Ren, Yachun Li, Hongchao Shi, Cihui Liu
Summary: Effective management of biofluids is crucial for in vivo surgical interventions. Recent advances include self-sealing needles, drug-eluting stents, and shear-thinning hydrogels. However, complications associated with intestinal mucosal injury and secondary damage still persist. In this study, researchers developed an interpenetrating Janus wettability stent coating that enables unidirectional draining of excessive biofluid. They also demonstrated directional biofluid movement using a self-pumping dressing with potential applications in biofluid collection and disease diagnosis through metal ion detection. This integrated system presents an opportunity for designing wound dressings with effective biofluid management and metal ion detection capabilities.
COLLOIDS AND SURFACES B-BIOINTERFACES
(2024)
Article
Biophysics
Maryam Hassani, Mojtaba Kamankesh, Mazda Rad-Malekshahi, Kobra Rostamizadeh, Farhad Rezaee, Ismaeil Haririan, Seyed Mojtaba Daghighi
Summary: Bacterial adhesion and biofilm formation on the surface of biomaterial implants is a critical problem, and a polymer brush coating with antiadhesive and antimicrobial properties has proven to be highly effective in resolving this issue.
COLLOIDS AND SURFACES B-BIOINTERFACES
(2024)
Article
Biophysics
Huaihong Zhang, Na Liu, Yuting Zhang, Hui Cang, Zhaosheng Cai, Ziqun Huang, Jun Li
Summary: A functionalized cationic polymer, CR-PQAC, was designed and synthesized for photothermal enhanced antimicrobial therapy. The CR-PQAC nanoparticles exhibited significant antibacterial activity and low cytotoxicity against mammalian cells.
COLLOIDS AND SURFACES B-BIOINTERFACES
(2024)
Article
Biophysics
Ipsita Sahu, Priyadarshi Chakraborty
Summary: Peptide nanotechnology bridges the gap between materials and biological worlds by utilizing self-assembly of short-peptide building blocks. Hydrogels engineered from these short peptides show great potential in biomedical applications, but their weak mechanical properties and limited functional diversity need to be addressed. Nanoengineering the networks of these hydrogels by incorporating small molecules, polymers, and inorganic/carbon nanomaterials can enhance their mechanical properties and expand their functional diversity.
COLLOIDS AND SURFACES B-BIOINTERFACES
(2024)
Article
Biophysics
Hao Wei, Yajun Gu, Ao Li, Panpan Song, Dingding Liu, Feihu Sun, Xiaofeng Ma, Xiaoyun Qian
Summary: In this study, a stable three-dimensional conductive hydrogel was prepared by cross-linking MXenes to Matrigel hydrogel. The conductive hydrogel promotes the proliferation and differentiation of NSCs, providing new strategies for neural tissue engineering.
COLLOIDS AND SURFACES B-BIOINTERFACES
(2024)
Article
Biophysics
Yue Zhong, Xiaoli Ge, Juan Zhang, Qun Wei, Feng Wang, Yongke Zhong
Summary: The effect of oxygenic groups on the hemocompatibility of activated carbon was studied through liquid-phase oxidation and subsequent heat treatment. Results showed that the presence of oxygenic groups improved hemocompatibility, while their removal decreased it.
COLLOIDS AND SURFACES B-BIOINTERFACES
(2024)
