期刊
COLLOIDS AND SURFACES A-PHYSICOCHEMICAL AND ENGINEERING ASPECTS
卷 375, 期 1-3, 页码 23-29出版社
ELSEVIER
DOI: 10.1016/j.colsurfa.2010.11.029
关键词
Cellulose acetate; Poly-L-lysine; Nanoparticle; Nanoprecipitation mechanism; Solvent displacement; Ultrathin layer
资金
- European Union [FP7/2007-2013, 214653]
An efficient nanoprecipitation technique using good cellulose acetate (CA) solvents as modifier for the dispersive media (nonsolvent) was developed for the generation of CA nanoparticles. Addition of tetrahydrofuran (THF) to the nonsolvent leads to smaller particles than obtained with pure water or standard stabilizing agents like surfactants and block copolymers. Sonication, efficient agitation, and optimization of process parameters like temperature, THF content, pH value and stirrer velocity reduces nanoparticle sizes and improves substrate recoveries. With the optimized process, spherical nanoparticles of 60 nm with 87% yield can be generated reproducibly. This is obtained by addition of good polymer solvents (tetrahydrofuran (THF)) to a nonsolvent (water) and applying those mixtures as nonsolvents for nanoprecipitation. Main theoretical models in discussion are not able to explain sufficiently the particle size reduction by the addition of a good polymer solvent to the nonsolvent. CA nanoparticles can be used to produce ultrathin layers deposited onto positively charged surfaces. Possible applications are seen in surface science (e.g. surface modifications and surface functionalization of CA foils and membranes). (C) 2010 Elsevier B.V. All rights reserved.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据