Article
Otorhinolaryngology
Catherine Sobieski, Daniel E. Killeen, Samuel L. Barnett, Bruce E. Mickey, Jacob B. Hunter, Brandon Isaacson, Joe Walter Kutz
Summary: Facial nerve outcomes one year after microsurgical resection are poorer in patients with NF2 tumors compared to sporadic tumors, particularly for tumors with a volume greater than 3 cm³ and those classified as NF2 tumors.
OTOLARYNGOLOGY-HEAD AND NECK SURGERY
(2021)
Article
Clinical Neurology
Felix Arlt, Johannes Kasper, Dirk Winkler, Katja Jaehne, Michael Karl Fehrenbach, Juergen Meixensberger, Caroline Sander
Summary: Intraoperative neurophysiological monitoring is crucial in vestibular schwannoma surgery to prevent nerve injury. Repeated direct nerve stimulation and a detected decreased amplitude might show facial nerve function deterioration.
FRONTIERS IN NEUROLOGY
(2022)
Article
Medicine, Research & Experimental
Daniel E. Killeen, Samuel L. Barnett, Bruce E. Mickey, Jacob B. Hunter, Brandon Isaacson, Joe Walter Kutz
Summary: The study revealed that patients with tumor volume >3 cm(3) had worse facial nerve outcomes 12 months following surgical resection. Tumor volume was identified as a key factor affecting facial nerve function outcomes.
Article
Oncology
Giuseppe Di Perna, Raffaele De Marco, Bianca Maria Baldassarre, Enrico Lo Bue, Fabio Cofano, Pietro Zeppa, Luca Ceroni, Federica Penner, Antonio Melcarne, Diego Garbossa, Michele Maria Lanotte, Francesco Zenga
Summary: This retrospective study aimed to investigate the impact of morphologic and neurophysiological factors on the short- and long-term facial nerve function after vestibular schwannoma resection. A multiparametric score, Facial Nerve Outcome Score (FNOS), was developed and shown to be a reliable predictor of facial nerve function.
FRONTIERS IN ONCOLOGY
(2023)
Article
Medicine, Research & Experimental
Candace E. Hobson, Joe Saliba, Nopawan Vorasubin, Robert H. Lyles, Bill Mastrodimos, Roberto A. Cueva
Summary: This study shows that the position of vestibular schwannoma relative to the IAC axis can be used along with tumor size to predict postoperative facial outcomes. A greater proportion of tumor posterior to the IAC axis was associated with significantly better facial outcomes.
Review
Clinical Neurology
Saba Raza-Knight, Sacha Chiuta, Aprajay Golash, Nihal Gurusinghe, Gareth Roberts, Andrew F. Alalade
Summary: Endoscopy-assisted or fully endoscopic procedures for sporadic VS resection have comparable facial nerve outcomes and extent of resection to microsurgery, with potential higher functional facial nerve preservation rates for smaller tumors using endoscopic assistance. However, hearing outcomes and the overall impact on outcomes remain variable and warrant further prospective studies.
OTOLOGY & NEUROTOLOGY
(2022)
Review
Medicine, General & Internal
Leonardo Franz, Gino Marioni, Antonio Mazzoni, Cosimo de Filippis, Elisabetta Zanoletti
Summary: This narrative review provides an update on the patho-physiological and clinical issues related to facial nerve damage in oto-neurological and skull base surgery. The occurrence of intraoperative facial nerve damage is associated with the anatomical relationship between tumor and nerve, the trajectory of the surgical corridor, and the boundaries of the resection margins. Mechanisms such as stretching, compression, devascularization, and heating may contribute to intraoperative facial nerve damage and nerve regeneration disorders.
JOURNAL OF CLINICAL MEDICINE
(2023)
Article
Neurosciences
Kathrin Machetanz, Florian Grimm, Ruth Schaefer, Leonidas Trakolis, Helene Hurth, Patrick Haas, Alireza Gharabaghi, Marcos Tatagiba, Georgios Naros
Summary: This study introduces a cost-effective custom-made EMG biofeedback system for facial rehabilitation, demonstrating its good application potential in both healthy subjects and patients with facial palsy. There is a correlation between electrophysiological measurements and clinical outcomes.
FRONTIERS IN NEUROSCIENCE
(2022)
Review
Medicine, Research & Experimental
Longping Yao, Baoyan Wang, Fengfei Lu, Xiaozheng He, Guohui Lu, Shizhong Zhang
Summary: The facial nerve, a mixed nerve, has sensory and motor fibers, with its main branch located in the cerebellopontine angle. Facial nerve dysfunction can occur in skullbase tumors and Bell's palsy, with recovery outcomes varying between the two. Recent advances in MRI technology have allowed for better visualization of the facial nerve in the presence of large tumors.
EUROPEAN JOURNAL OF MEDICAL RESEARCH
(2023)
Article
Medicine, Research & Experimental
Isaac D. Erbele, Micah L. Klumpp, Moises A. Arriaga
Summary: Preoperative functional testing cannot reliably predict the presence of intracranial facial schwannomas. Hearing is better in facial schwannomas, especially in lower frequencies, while patients with vestibular schwannomas have worse hearing outcomes.
Editorial Material
Clinical Neurology
Ufuk Erginoglu, Walid Elshamy, Mustafa K. Baskaya
Summary: Preserving facial nerve function is crucial in translabyrinthine approach for vestibular schwannoma surgery. Anatomical variations in the facial nerve are rare but can be associated with congenital abnormalities. We present a rare case of vestibular schwannoma with a bifurcated facial nerve. The patient had a successful postoperative recovery with Grade I outcome. This case highlights the importance of identifying and preserving the facial nerve during vestibular schwannoma resection.
WORLD NEUROSURGERY
(2022)
Article
Biophysics
Qingrun Zeng, Mengjun Li, Shaonan Yuan, Jianzhong He, Jingqiang Wang, Zan Chen, Changchen Zhao, Ge Chen, Jiantao Liang, Mingchu Li, Yuanjing Feng
Summary: The study addresses the challenges of tractography of the facial-vestibulocochlear nerve complex due to small size and intricate anatomical environment. By creating an FVN template and performing data-driven fiber clustering, the researchers developed a pipeline for automatic identification of FVN, which showed promising results on healthy and tumor patient datasets, with good spatial overlap and visualization matching expert manual identification.
NMR IN BIOMEDICINE
(2021)
Article
Clinical Neurology
Yang Sun, Jianhua Yang, Tang Li, Kaiming Gao, Xiaoguang Tong
Summary: This study has established a new nomogram for predicting the rates of poor facial nerve outcomes after vestibular schwannoma surgery, which includes significant prognostic factors. The nomogram showed good discrimination and calibration in the validation cohort.
FRONTIERS IN NEUROLOGY
(2022)
Article
Clinical Neurology
Mohamed Elsayed, Huan Jia, Baptiste Hochet, Olivier Sterkers, Renato Torres, Yann Nguyen, Isabelle Bernat, Ghizlene Lahlou, Michel Kalamarides
Summary: Decision-making for large sporadic vestibular schwannomas resection can be guided by intraoperative monitoring of maximal facial nerve amplitude and latency response to optimize post-operative results. Tumors were removed through retrosigmoid or translabyrinthine approaches in patients with normal preoperative FN function, achieving some tumor removal while maintaining a certain decrease in amplitude. Good postoperative facial nerve function and significant hearing preservation were achieved after 6 months, with no significant difference observed between TR and NTR+STR procedures.
ACTA NEUROCHIRURGICA
(2021)
Article
Clinical Neurology
Nolan Ung, Panayotis E. Pelargos, Khashayar Mozaffari, Monica Mathur, Courtney Duong, Lawrance K. Chung, Kevin Ding, Nikhilesh S. Bhatt, Natalie Barnette, Brittany Voth, Quinton Gopen, Isaac Yang
Summary: DTI tractography is an accurate tool to visualize and locate the facial nerve during surgical resection of Vestibular Schwannomas, potentially reducing postoperative facial nerve damage.
JOURNAL OF THE NEUROLOGICAL SCIENCES
(2021)
Article
Clinical Neurology
Hui Luo, Zhengxin Chen, Shuai Wang, Rui Zhang, Wenjin Qiu, Lin Zhao, Chenghao Peng, Ran Xu, Wanghao Chen, Hong-Wei Wang, Yuanyuan Chen, Jingmin Yang, Xiaotian Zhang, Shuyu Zhang, Dan Chen, Wenting Wu, Chunsheng Zhao, Gang Cheng, Tao Jiang, Daru Lu, Yongping You, Ning Liu, Huibo Wang
Article
Multidisciplinary Sciences
Chao Lin, Hongquan He, Zheng Li, Yinglong Liu, Honglu Chao, Jing Ji, Ning Liu
SCIENTIFIC REPORTS
(2015)
Article
Neurosciences
Ying-Yi Wang, Guan Sun, Hui Luo, Xie-Feng Wang, Feng-Ming Lan, Xiao Yue, Lin-Shan Fu, Pei-Yu Pu, Chun-Sheng Kang, Ning Liu, Yong-Ping You
CNS NEUROSCIENCE & THERAPEUTICS
(2012)
Article
Multidisciplinary Sciences
Qingsheng Dong, Ning Cai, Tao Tao, Rui Zhang, Wei Yan, Rui Li, Junxia Zhang, Hui Luo, Yan Shi, Wenkang Luan, Yaxuan Zhang, Yongping You, Yingyi Wang, Ning Liu
Article
Biochemistry & Molecular Biology
Zhu-mei Shi, Xie-feng Wang, Xu Qian, Tao Tao, Lin Wang, Qiu-dan Chen, Xi-rui Wang, Lei Cao, Ying-yi Wang, Jun-xia Zhang, Tao Jiang, Chun-sheng Kang, Bing-hua Jiang, Ning Liu, Yong-ping You
Article
Oncology
Tongle Zhi, Kuan Jiang, Xiupeng Xu, Tianfu Yu, Fengqi Zhou, Yingyi Wang, Ning Liu, Junxia Zhang