Article
Psychology, Clinical
Nithya Ramakrishnan, Marijn Lijffijt, Charles E. Green, Nicholas L. Balderston, Nicholas Murphy, Christian Grillon, Tabish Iqbal, Brittany Vo-Le, Brittany O'Brien, James W. Murrough, Alan C. Swann, Sanjay J. Mathew
Summary: The study demonstrated successful occupancy of lanicemine on NMDAR and effects on arousal symptoms. While lanicemine strongly attenuated APS following a single infusion, differential changes from placebo after three infusions may have been obscured by habituation effects. This research supports selective NMDAR antagonism as a viable pharmacological strategy for treating salient aspects of PTSD.
DEPRESSION AND ANXIETY
(2021)
Review
Psychology, Multidisciplinary
Robert Raeder, Nicola S. Clayton, Markus Boeckle
Summary: This systematic review and meta-analysis provides strong evidence for the efficacy of narrative-based interventions (NBIs) in the treatment of post-traumatic stress disorder (PTSD). The results show that NBIs significantly decrease PTSD symptomatology both immediately after treatment and at 3-9 month follow-up assessments. Furthermore, NBIs are superior to active and waitlist controls, indicating their effectiveness in treating PTSD.
FRONTIERS IN PSYCHOLOGY
(2023)
Article
Psychiatry
Gregory M. Sullivan, R. Michael Gendreau, Judith Gendreau, Perry Peters, Ashild Peters, Jean Engels, Bruce L. Daugherty, Benjamin Vaughn, Frank W. Weathers, Seth Lederman
Summary: This study suggests that TNX-102 SL 5.6 mg reduces PTSD symptoms, improves sleep and psychosocial function, and is well tolerated.
PSYCHIATRY RESEARCH
(2021)
Article
Psychiatry
Thauana Torres Oliveira-Watanabe, Luis Francisco Ramos-Lima, Cecilia Zylberstajn, Vinicius Calsavara, Bruno Messina Coimbra, Mariana Rangel Maciel, Lucia Helena Machado Freitas, Marcelo Feijo Mello, Andrea Feijo Mello
Summary: The study validated the reliability of CAPS-5 in Brazilian-Portuguese, with a 15-item model showing high internal consistency.
FRONTIERS IN PSYCHIATRY
(2021)
Article
Biochemistry & Molecular Biology
Jennifer M. Mitchell, G. Marcela Ot'alora, Bessel van der Kolk, Scott Shannon, Michael Bogenschutz, Yevgeniy Gelfand, Casey Paleos, Christopher R. Nicholas, Sylvestre Quevedo, Brooke Balliett, Scott Hamilton, Michael Mithoefer, Sarah Kleiman, Kelly Parker-Guilbert, Keren Tzarfaty, Charlotte Harrison, Alberdina de Boer, Rick Doblin, Berra Yazar-Klosinski
Summary: This study evaluated the efficacy and safety of MDMA-AT in participants with moderate to severe PTSD. The results showed that MDMA-AT significantly reduced the severity of symptoms and functional impairment, and was well tolerated by a diverse population.
Article
Clinical Neurology
Carter E. Bedford, Norman B. Schmidt
Summary: This study evaluated the effect of a brief computer-based intervention (SBETS) on posttraumatic stress symptoms (PTSS). The results showed that SBETS had a significant impact on PTSS and could be considered as an accessible and acceptable treatment option for trauma survivors.
JOURNAL OF AFFECTIVE DISORDERS
(2023)
Article
Psychology, Clinical
Lindsay B. Kramer, Sarah E. Whiteman, Jessica M. Petri, Elizabeth G. Spitzer, Frank W. Weathers
Summary: This study aimed to replicate previously identified discrepancies and examine the possible objective predictors and subjective sources of these discrepancies. The findings suggest that discrepancies between self-rated and clinician-rated measures of PTSD may arise from factors such as time-frame reminders, comprehension of symptoms, trauma-related attribution errors, increased awareness, and general errors.
Article
Psychology, Clinical
Catalin Nedelcea, Iulia D. Ciorbea, Diana L. Vasile, Serban Ionescu, Claudiu Papasteri, Ramona D. Letzner, Ana Cosmoiu, Teodora Georgescu
Summary: This study aimed to improve the assessment of PTSD in a Marxist-Leninist cultural context by developing an alternative self-report measure, which showed excellent psychometric properties in terms of internal consistency, temporal reliability, and validity. The research also revealed important findings regarding symptom clusters and activation patterns in high-risk groups.
EUROPEAN JOURNAL OF PSYCHOTRAUMATOLOGY
(2022)
Article
Psychology, Clinical
Ida Hensler, Josefin Sveen, Martin Cernvall, Filip K. Arnberg
Summary: The Swedish version of the self-management app PTSD Coach has been found to benefit posttraumatic stress and depressive symptoms after three months use. This study also evaluated the effects of the app on functional disability and described negative effects, helpfulness, and satisfaction with the app. Overall, symptoms of posttraumatic stress, depression, somatic illness, and functional disability decreased and were maintained within 3 to 9 months of app access.
INTERNET INTERVENTIONS-THE APPLICATION OF INFORMATION TECHNOLOGY IN MENTAL AND BEHAVIOURAL HEALTH
(2023)
Article
Medicine, Research & Experimental
Lei Yi, Yunling Lian, Ning Ma, Ni Duan
Summary: This study found that yoga intervention can alleviate anxiety and depression, and improve symptoms for women with PTSD who are survivors of motor vehicle accidents.
JOURNAL OF TRANSLATIONAL MEDICINE
(2022)
Article
Psychiatry
Carolin Steuwe, Michaela Berg, Thomas Beblo, Martin Driessen
Summary: The study found that both NET and DBT-bt significantly improved symptoms in patients with comorbid BPD and PTSD, with no significant difference in improvement between the two treatments. However, NET had a higher remission rate than DBT-bt, and remission of PTSD was associated with remission of BPD in all cases.
FRONTIERS IN PSYCHIATRY
(2021)
Article
Psychology, Clinical
Yaron Alon, Omer Azriel, Daniel S. Pine, Yair Bar-Haim
Summary: This study examined remotely-delivered attention bias modification (ABM) and attention control training (ACT) for PTSD treatment. Results showed that both ACT and ABM led to significant symptom reduction, with ACT showing advantages in non-depressed patients and patients whose trauma occurred more recently. Further refinements in remote ABM/ACT treatments may be necessary.
PSYCHOLOGICAL MEDICINE
(2023)
Article
Psychology, Clinical
Richard M. Gray, Denise Budden-Potts, Richard J. Schwall, Frank F. Bourke
Summary: PTSD in female veterans and service members is understudied, and new, effective treatments are needed. Reconsolidation of Traumatic Memories (RTM) was found to be effective in treating PTSD in military women, with significant results replicated from previous studies on male populations. Further research is recommended.
PSYCHOLOGICAL TRAUMA-THEORY RESEARCH PRACTICE AND POLICY
(2021)
Article
Health Care Sciences & Services
Kyle Possemato, Emily Johnson, Kimberly Barrie, Sharfun Ghaus, Delilah Noronha, Michael Wade, Mark A. Greenbaum, Craig Rosen, Marylene Cloitre, Jason Owen, Shaili Jain, Gregory Beehler, Annabel Prins, Karen Seal, Eric Kuhn
Summary: This study tested the effectiveness of a brief primary care-based treatment in reducing the severity of PTSD and improving patient satisfaction. The results showed that the treatment resulted in more patient-reported symptom relief and higher treatment satisfaction, but did not show a significant improvement in clinician-rated PTSD severity.
JOURNAL OF GENERAL INTERNAL MEDICINE
(2023)
Article
Plant Sciences
Wing Fai Yeung, Branda Yee-Man Yu, Ka-Fai Chung, Zhang-Jin Zhang, Lixing Lao, Fiona Yan-Yee Ho, Lorna Kwai-Ping Suen, Lai-Ming Ho
Summary: The study demonstrates that self-administered acupressure learned through a training course has significant effects in alleviating insomnia disorder, improving related daytime impairment, and mood problems. This provides a feasible self-management approach for individuals with insomnia.
Article
Psychology, Developmental
Patricia Paiva de Oliveira Galvao, Juliana Yurgel Valente, Hugo Cogo-Moreira, Jair J. Mari, Zila M. Sanchez
Summary: This study investigates the association between being a victim of bullying and body dissatisfaction as well as eating disorder behavior (EDB) among Brazilian middle school students. The results suggest that being a victim of bullying predicts a higher likelihood of engaging in EDB, independent of exposure to intervention programs. However, bullying itself is not directly associated with body dissatisfaction. The study highlights the importance of addressing bullying in school environments.
CHILD PSYCHIATRY & HUMAN DEVELOPMENT
(2023)
Article
Psychology, Developmental
Cezar H. Lorenzi, Douglas Teixeira Leffa, Rodrigo Bressan, Sintia Belangero, Ary Gadelha, Marcos L. Santoro, Giovanni A. Salum, Luis Augusto Rohde, Arthur Caye
Summary: This study validates the performance of an ADHD predictive model, showing it to be effective in developed countries but not in a developing country. The findings suggest that the model can be used in different clinical and research settings.
JOURNAL OF CHILD PSYCHOLOGY AND PSYCHIATRY
(2023)
Article
Criminology & Penology
Ricardo A. F. DeMello, Bruno Messina Coimbra, Bianca D. M. Pedro, Isabella M. Benvenutti, Mary S. L. Yeh, Andrea F. Mello, Marcelo F. Mello, Dalva R. Poyares
Summary: This study investigated the association between tonic immobility (TI) and peri-traumatic dissociation (PTD) with posttraumatic stress disorder (PTSD) in women who experienced sexual violence. The results showed a significant positive correlation between PTD and PTSD severity, as well as anxiety and depressive symptoms. Risk factors for PTD occurrence included history of physical and sexual abuse during childhood, lower education, and lower income. TI was not associated with PTSD severity.
JOURNAL OF INTERPERSONAL VIOLENCE
(2023)
Article
Psychology, Clinical
Marina S. Borges, Mauricio S. Hoffmann, Andre Simioni, Luiza K. Axelrud, Danielle S. Teixeira, Andre Zugman, Andrea Jackowski, Pedro M. Pan, Rodrigo A. Bressan, Nadine Parker, Jurgen Germann, Patricia P. Bado, Theodore D. Satterthwaite, Michael P. Milham, M. Mallar Chakravarty, Luis Augusto Paim Rohde, Euripedes Constantino Miguel, Tomas Paus, Giovanni A. Salum
Summary: This study investigates the relationship between deviations in cerebellar volume and psychopathology, executive functions, and academic achievement in children and adolescents. The findings suggest that deviations in typical cerebellar development are associated with long-lasting consequences in youth. This study highlights the potential of typical developing models and emphasizes the important role of the cerebellum in mental health, cognition, and education.
PSYCHOLOGICAL MEDICINE
(2023)
Article
Psychology, Clinical
Cecilia Zylberstajn, Bruno Messina Coimbra, Thauana T. Oliveira-Watanabe, Mariana Rangel Maciel, Vinicius F. Calsavara, Miranda Olff, Marcelo Feijo Mello, Andrea Feijo Mello
Summary: This study investigated the relationship between PTEs, PD, and PTSD in sexually assaulted women. The results showed that lifetime exposure to PTEs was a risk factor for PD, but PD was not a risk factor for PTSD severity nor a mediator between PTEs and PTSD severity.
JOURNAL OF TRAUMA & DISSOCIATION
(2023)
Article
Psychiatry
Stefania Tognin, Ana Catalan, Matthew J. Kempton, Barnaby Nelson, Patrick McGorry, Anita Riecher-Rossler, Rodrigo Bressan, Neus Barrantes-Vidal, Marie-Odile Krebs, Merete Nordentoft, Stephan Ruhrmann, Gabriele Sachs, Bart P. F. Rutten, Jim van Os, Lieuwe de Haan, Mark van der Gaag, Philip R. McGuire, Lucia Valmaggia
Summary: Research shows that adverse childhood experiences (ACE) can impact educational achievements in individuals at clinical high risk of psychosis (CHR). Specifically, CHR individuals with ACE had lower education levels, employment rates, and estimated IQ compared to healthy controls. Early intervention programs for psychosis should integrate interventions to support the educational and vocational recovery of young CHR individuals, and public health and social interventions to prevent or reduce the impact of ACE are recommended.
EUROPEAN PSYCHIATRY
(2023)
Article
Psychiatry
Emily J. Hird, Noriyuki Ohmuro, Paul Allen, Peter Moseley, Matthew J. Kempton, Gemma Modinos, Gabriele Sachs, Mark van der Gaag, Lieuwe de Haan, Ary Gadelha, Rodrigo Bressan, Neus Barrantes-Vidal, Stephan Ruhrmann, Ana Catalan, Philip McGuire
Summary: The study found that individuals at clinical high risk for psychosis have a lower sensitivity to hearing speech in noise and uncertainty about the affective valence of this speech, which is associated with adverse clinical outcomes. The findings suggest that the ability to hear speech illusions in noise could be used as a cognitive marker to predict the likelihood of remission or transition to psychosis in individuals at risk.
SCHIZOPHRENIA BULLETIN
(2023)
Article
Psychiatry
Jessica Honorato-Mauer, Gabriela Xavier, Vanessa Kiyomi Ota, Samar Nasser Chehimi, Fernanda Mafra, Cassia Cuoco, Lucas Toshio Ito, Rafaella Ormond, Paula Fontes Asprino, Adrielle Oliveira, Amanda Victoria Gomes Bugiga, Ana Claudia Torrecilhas, Rodrigo Bressan, Gisele Gus Manfro, Euripedes Constantino Miguel, Luis Augusto Rohde, Pedro Mario Pan, Giovanni Abrahao Salum, Renata Pellegrino, Sintia Belangero, Marcos Leite Santoro
Summary: This study analyzed the expression of microRNAs (miRNAs) in serum extracellular vesicles (EVs) from adolescents and found a correlation between miRNA expression and mental health disorders. The results provide support for further research on utilizing EVs miRNAs as biomarkers for mental health disorders.
TRANSLATIONAL PSYCHIATRY
(2023)
Review
Psychiatry
Carlos Gustavo Costardi, Ana Carolina C. D'agostini, Pedro Mario Pan, Rodrigo Affonseca Bressan
Summary: This article aims to synthesize the evidence for digital mental health interventions for school teachers. A literature search retrieved 11 studies that fulfilled the inclusion criteria. Although these interventions had some impact on the mental health of school teachers, there were limitations in study designs and data quality, as well as a need for effective evidence-based interventions.
EARLY INTERVENTION IN PSYCHIATRY
(2023)
Article
Behavioral Sciences
Joao Ricardo Sato, Claudinei Eduardo Biazoli, Ana Paula Arantes Bueno, Arthur Caye, Pedro Mario Pan, Marcos Santoro, Jessica Honorato-Mauer, Giovanni Abrahao Salum, Marcelo Queiroz Hoexter, Rodrigo Affonseca Bressan, Andrea Parolin Jackowski, Euripedes Constantino Miguel, Sintia Belangero, Luis Augusto Rohde
Summary: Neuroimaging studies suggest that brain development mechanisms may explain some ADHD symptoms. However, the mechanisms by which genetic factors influence brain development in relation to ADHD remain largely unknown. This study aimed to investigate the associations between an ADHD polygenic risk score and brain network functioning. The findings suggest correlations between the ADHD polygenic risk score and the segregation of cingulo-opercular networks and the default mode network, supporting the role of attentional networks and DMN in attention processes. However, these associations were not found at follow-up.
GENES BRAIN AND BEHAVIOR
(2023)
Article
Psychiatry
Matheus Ghossain Barbosa, Viviane Machado, Carolina Ziebold, Tais Moriyama, Rodrigo A. Bressan, Pedro Pan, Luis Augusto Rohde, Euripedes Constantino Miguel, Lais Fonseca, Jim Van Os, Ary Gadelha
Summary: The Brazilian High-Risk Cohort study examined the measurement invariance of the CAPE-positive scale in children and adolescents over a three-year period. The results show that the scale is not invariant over time, indicating the need for further investigation into the factors influencing its results.
SCHIZOPHRENIA RESEARCH
(2023)
Article
Political Science
Regiane Nitsch Bressan, Julia de Souza Borba Goncalves
Summary: This article analyzes the relationship dynamics between the Pacific Alliance and Mercosur from 2011 to 2022, focusing on their moments of advancement and retraction. Based on data analysis and literature review, it suggests that the initial competition between the two regional processes has been overcome by efforts to manage their differences, leading to ongoing dialogue. However, the challenges of Latin American integration and ideological differences among national governments hinder the establishment of common trade policies, requiring cooperation beyond tariff elimination. Restoring the convergence agenda will depend on political willingness and engagement from economic elites.
LATIN AMERICAN POLICY
(2023)
Article
Psychiatry
Ana Paula Aguiar, Angel Olider Rojas Vistorte, Henrique Teruo Akiba, Paula Oliveira, Deise Palermo Puertas Ruiz, Ary Gadelha, Rodrigo Affonseca Bressan, Pedro Mario Pan
Summary: Methods to prospectively identify individuals at high risk of developing psychosis have been proposed, and this study translated and adapted two screening tools (PQ-16 and PRIME-Screen) into Brazilian Portuguese. After translation and cross-cultural adaptation, these new instruments can be used to screen Brazilian Portuguese-speaking patients who are at risk of psychosis in primary care.
TRENDS IN PSYCHIATRY AND PSYCHOTHERAPY
(2023)
Correction
Psychiatry
David Mongan, Melanie Focking, Colm Healy, Subash Raj Susai, Meike Heurich, Kieran Wynne, Barnaby Nelson, Patrick D. McGorry, Paul Amminger, Merete Nordentoft, Marie-Odile Krebs, Anita Riecher-Rossler, Rodrigo A. Bressan, Neus Barrantes-Vidal, Stefan Borgwardt, Stephan Ruhrmann, Gabriele Sachs, Christos Pantelis, Mark van der Gaag, Lieuwe de Haan, Lucia Valmaggia, Thomas A. Pollak, Matthew J. Kempton, Bart P. F. Rutten, Robert Whelan, Mary Cannon, Stan Zammit, Gerard Cagney, David R. Cotter, Philip McGuire
Article
Substance Abuse
Renata Faro Guerra, Ilza Rosa Batista, Hyoun S. Kim, Marcelo Queiroz Hoexter, Ming Chi Shih, Rodrigo Affonseca Bressan, Hermano Tavares
Summary: The aim of this research was to investigate the association between dopamine transporter (DAT) density in the ventral striatum and gambling disorder (GD). The results suggest that DAT density in the striatum is associated with recent gambling activity and gambling expectation.
JOURNAL OF GAMBLING STUDIES
(2023)