PPAR-γ Agonism as a Modulator of Mood: Proof-of-Concept for Pioglitazone in Bipolar Depression

Lurasidone as Adjunctive Therapy With Lithium or Valproate for the Treatment of Bipolar I Depression: A Randomized, Double-Blind, Placebo-Controlled Study

(2013) Antony Loebel et al.   AMERICAN JOURNAL OF PSYCHIATRY

Lurasidone Monotherapy in the Treatment of Bipolar I Depression: A Randomized, Double-Blind, Placebo-Controlled Study

(2013) Antony Loebel et al.   AMERICAN JOURNAL OF PSYCHIATRY

Bidirectional Association Between Depression and Metabolic Syndrome: A systematic review and meta-analysis of epidemiological studies

(2012) A. Pan et al.   DIABETES CARE

Pro-inflammatory cytokines as predictors of antidepressant effects of exercise in major depressive disorder

(2012) C D Rethorst et al.   MOLECULAR PSYCHIATRY

Pioglitazone Adjunctive Therapy for Moderate-to-Severe Major Depressive Disorder: Randomized Double-Blind Placebo-Controlled Trial

(2012) Khatereh Sepanjnia et al.   NEUROPSYCHOPHARMACOLOGY

Adiponectin is critical in determining susceptibility to depressive behaviors and has antidepressant-like activity

(2012) Jing Liu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Antidepressant-like effect of pioglitazone in the forced swimming test in mice: The role of PPAR-gamma receptor and nitric oxide pathway

(2011) Mohammad Salehi Sadaghiani et al.   BEHAVIOURAL BRAIN RESEARCH

Use of insulin sensitizers for the treatment of major depressive disorder: A pilot study of pioglitazone for major depression accompanied by abdominal obesity

(2011) David E. Kemp et al.   JOURNAL OF AFFECTIVE DISORDERS

Possible implications of insulin resistance and glucose metabolism in Alzheimer’s disease pathogenesis

(2011) Domenico Bosco et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

Insulin Modulates Cocaine-Sensitive Monoamine Transporter Function and Impulsive Behavior

(2011) A. N. M. Schoffelmeer et al.   JOURNAL OF NEUROSCIENCE

Increased levels of adipokines in bipolar disorder

(2011) Izabela Guimarães Barbosa et al.   JOURNAL OF PSYCHIATRIC RESEARCH

A role for central nervous system PPAR-γ in the regulation of energy balance

(2011) Karen K Ryan et al.   NATURE MEDICINE

Translating Discoveries into Medicine: Psychiatric Drug Development in 2011

(2011) Linda S Brady et al.   NEUROPSYCHOPHARMACOLOGY

Psychoneuroimmunology Meets Neuropsychopharmacology: Translational Implications of the Impact of Inflammation on Behavior

(2011) Ebrahim Haroon et al.   NEUROPSYCHOPHARMACOLOGY

A Randomized Add-on Trial of an N-methyl-D-aspartate Antagonist in Treatment-Resistant Bipolar Depression

(2010) Nancy Diazgranados et al.   ARCHIVES OF GENERAL PSYCHIATRY

Medical comorbidity in bipolar disorder: relationship between illnesses of the endocrine/metabolic system and treatment outcome

(2010) David E Kemp et al.   BIPOLAR DISORDERS

Second-generation antipsychotics in major depressive disorder: update and clinical perspective

(2010) Jun Chen et al.   CURRENT OPINION IN PSYCHIATRY

Pioglitazone: side effect and safety profile

(2010) Priya Shah et al.   Expert Opinion On Drug Safety

Low 24-Hour Adiponectin and High Nocturnal Leptin Concentrations in a Case-Control Study of Community-Dwelling Premenopausal Women With Major Depressive Disorder

(2010) Giovanni Cizza et al.   JOURNAL OF CLINICAL PSYCHIATRY

Time-Resolved and Tissue-Specific Systems Analysis of the Pathogenesis of Insulin Resistance

(2010) Robert Kleemann et al.   PLoS One

Antidepressant Response Associated With Pioglitazone: Support for an Overlapping Pathophysiology Between Major Depression and Metabolic Syndrome

(2009) DAVID E. KEMP et al.   AMERICAN JOURNAL OF PSYCHIATRY

Antidepressant-like effects of rosiglitazone, a PPARγ agonist, in the rat forced swim and mouse tail suspension tests

(2009) Amany Ali Eissa Ahmed et al.   BEHAVIOURAL PHARMACOLOGY

A Prospective Observational Study of Obesity, Body Composition, and Insulin Resistance in 18 Women With Bipolar Disorder and 17 Matched Control Subjects

(2009) Sara B. Fleet-Michaliszyn et al.   JOURNAL OF CLINICAL PSYCHIATRY

Metabolic Syndrome Predisposes to Depressive Symptoms

(2009) Hannu Koponen et al.   JOURNAL OF CLINICAL PSYCHIATRY

Obesity and Onset of Significant Depressive Symptoms

(2009) Nicole Vogelzangs et al.   JOURNAL OF CLINICAL PSYCHIATRY

C-reactive protein concentration and risk of coronary heart disease, stroke, and mortality: an individual participant meta-analysis

(2009)   LANCET

CSF concentrations of brain tryptophan and kynurenines during immune stimulation with IFN-α: relationship to CNS immune responses and depression

(2009) C L Raison et al.   MOLECULAR PSYCHIATRY

Higher plasma interleukin-6 (IL-6) level is associated with SSRI- or SNRI-refractory depression

(2009) Reiji Yoshimura et al.   PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY

Insulin, Insulin-Like Growth Factors??and Incretins

(2008) Roger S McIntyre et al.   CNS DRUGS

Examining a Bidirectional Association Between Depressive Symptoms and Diabetes

(2008) Sherita Hill Golden   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

IL-1 is an essential mediator of the antineurogenic and anhedonic effects of stress

(2008) J. W. Koo et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Association of adiponectin and resistin with cardiovascular events in Korean patients with type 2 diabetes: The Korean atherosclerosis study (KAS)

(2006) Soo Lim et al.   ATHEROSCLEROSIS