Serotonin 5-HT1A Receptors as Targets for Agents to Treat Psychiatric Disorders: Rationale and Current Status of Research

The serotonin 1A receptor gene confer susceptibility to mood disorders: results from an extended meta-analysis of patients with major depression and bipolar disorder

(2012) Taro Kishi et al.   EUROPEAN ARCHIVES OF PSYCHIATRY AND CLINICAL NEUROSCIENCE

Increased Serotonin-1A (5-HT1A) Autoreceptor Expression and Reduced Raphe Serotonin Levels in Deformed Epidermal Autoregulatory Factor-1 (Deaf-1) Gene Knock-out Mice

(2012) Margaret Czesak et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Serotonin receptors involved in antidepressant effects

(2012) Francesc Artigas   PHARMACOLOGY & THERAPEUTICS

Acute 5-HT1A autoreceptor knockdown increases antidepressant responses and serotonin release in stressful conditions

(2012) Albert Ferrés-Coy et al.   PSYCHOPHARMACOLOGY

The role of 5-HT1A receptors in phencyclidine (PCP)-induced novel object recognition (NOR) deficit in rats

(2012) M. Horiguchi et al.   PSYCHOPHARMACOLOGY

Biased agonism at serotonin 5-HT1A receptors: preferential postsynaptic activity for improved therapy of CNS disorders

(2012) Adrian Newman-Tancredi   Neuropsychiatry

Preclinical and clinical characterization of the selective 5-HT1Areceptor antagonist DU-125530 for antidepressant treatment

(2011) MC Scorza et al.   BRITISH JOURNAL OF PHARMACOLOGY

5-HT1A Receptor Agonists Enhance Pyramidal Cell Firing in Prefrontal Cortex Through a Preferential Action on GABA Interneurons

(2011) L. Llado-Pelfort et al.   CEREBRAL CORTEX

Cost of disorders of the brain in Europe 2010

(2011) Anders Gustavsson et al.   EUROPEAN NEUROPSYCHOPHARMACOLOGY

Serotonin-1A Autoreceptors Are Necessary and Sufficient for the Normal Formation of Circuits Underlying Innate Anxiety

(2011) J. W. Richardson-Jones et al.   JOURNAL OF NEUROSCIENCE

Selective siRNA-mediated suppression of 5-HT1A autoreceptors evokes strong anti-depressant-like effects

(2011) A Bortolozzi et al.   MOLECULAR PSYCHIATRY

In vivo electrophysiological and neurochemical effects of the selective 5-HT1A receptor agonist, F13640, at pre- and postsynaptic 5-HT1A receptors in the rat

(2011) Laia Lladó-Pelfort et al.   PSYCHOPHARMACOLOGY

Comparative pharmacology of antipsychotics possessing combined dopamine D2 and serotonin 5-HT1A receptor properties

(2011) Adrian Newman-Tancredi et al.   PSYCHOPHARMACOLOGY

Higher Serotonin 1A Binding in a Second Major Depression Cohort: Modeling and Reference Region Considerations

(2010) Ramin V. Parsey et al.   BIOLOGICAL PSYCHIATRY

Preferential in vivo action of F15599, a novel 5-HT1A receptor agonist, at postsynaptic 5-HT1A receptors

(2010) L Lladó-Pelfort et al.   BRITISH JOURNAL OF PHARMACOLOGY

5-HT1A receptor-regulated signal transduction pathways in brain

(2010) Abigail M. Polter et al.   CELLULAR SIGNALLING

Competitive interaction of 5-HT1A receptors with G-protein subtypes in CHO cells demonstrated by RNA interference

(2010) Isabelle Rauly-Lestienne et al.   CELLULAR SIGNALLING

Therapeutic Role of 5-HT1A Receptors in The Treatment of Schizophrenia and Parkinson's Disease

(2010) Yukihiro Ohno   CNS Neuroscience & Therapeutics

F15599, a preferential post-synaptic 5-HT1A receptor agonist: Activity in models of cognition in comparison with reference 5-HT1A receptor agonists

(2010) Ronan Depoortère et al.   EUROPEAN NEUROPSYCHOPHARMACOLOGY

Dopamine release induced by atypical antipsychotics in prefrontal cortex requires 5-HT1A receptors but not 5-HT2A receptors

(2010) Analía Bortolozzi et al.   INTERNATIONAL JOURNAL OF NEUROPSYCHOPHARMACOLOGY

Can We Really Accelerate and Enhance the Selective Serotonin Reuptake Inhibitor Antidepressant Effect?

(2010) Maria J. Portella et al.   JOURNAL OF CLINICAL PSYCHIATRY

5-HT1A Autoreceptor Levels Determine Vulnerability to Stress and Response to Antidepressants

(2010) Jesse W. Richardson-Jones et al.   NEURON

Synchronized Activity between the Ventral Hippocampus and the Medial Prefrontal Cortex during Anxiety

(2010) Avishek Adhikari et al.   NEURON

The serotonin1A receptor gene as a genetic and prenatal maternal environmental factor in anxiety

(2010) G. Gleason et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The role of serotonin receptor subtypes in treating depression: a review of animal studies

(2010) Gregory V. Carr et al.   PSYCHOPHARMACOLOGY

The prefrontal cortex: a target for antipsychotic drugs

(2009) F. Artigas   ACTA PSYCHIATRICA SCANDINAVICA

Signal transduction and functional selectivity of F15599, a preferential post-synaptic 5-HT1Areceptor agonist

(2009) A Newman-Tancredi et al.   BRITISH JOURNAL OF PHARMACOLOGY

Treatment of cognitive dysfunction in chronic schizophrenia by augmentation of atypical antipsychotics with buspirone, a partial 5-HT1Areceptor agonist

(2009) Danijela Piškulić et al.   HUMAN PSYCHOPHARMACOLOGY-CLINICAL AND EXPERIMENTAL

Subchronic Effects of Phencyclidine on Dopamine and Serotonin Receptors: Implications for Schizophrenia

(2009) Yong Kee Choi et al.   JOURNAL OF MOLECULAR NEUROSCIENCE

5-HT1A receptor function in major depressive disorder

(2009) Jonathan Savitz et al.   PROGRESS IN NEUROBIOLOGY

A Meta-Analysis of Head-to-Head Comparisons of Second-Generation Antipsychotics in the Treatment of Schizophrenia

(2008) Stefan Leucht et al.   AMERICAN JOURNAL OF PSYCHIATRY

The role of 5-HT1A receptors in learning and memory

(2008) Sven Ove Ögren et al.   BEHAVIOURAL BRAIN RESEARCH

Does stimulation of 5-HT1A receptors improve cognition in schizophrenia?

(2008) Herbert Y. Meltzer et al.   BEHAVIOURAL BRAIN RESEARCH

Serotonin 5-HT1A receptor binding in people with panic disorder: positron emission tomography study

(2008) Jon R. Nash et al.   BRITISH JOURNAL OF PSYCHIATRY

Pyramidal Neurons in Rat Prefrontal Cortex Projecting to Ventral Tegmental Area and Dorsal Raphe Nucleus Express 5-HT2A Receptors

(2008) P. Vazquez-Borsetti et al.   CEREBRAL CORTEX

5-HT1A Receptor, an Old Target for New Therapeutic Agents

(2008) Enza Lacivita et al.   CURRENT TOPICS IN MEDICINAL CHEMISTRY

Serotonin 1A receptors in human and monkey prefrontal cortex are mainly expressed in pyramidal neurons and in a GABAergic interneuron subpopulation: implications for schizophrenia and its treatment

(2008) Julián De Almeida et al.   JOURNAL OF NEUROCHEMISTRY

 -Ca2+/Calmodulin-Dependent Protein Kinase II Contributes to the Developmental Programming of Anxiety in Serotonin Receptor 1A Knock-Out Mice

(2008) L. Lo Iacono et al.   JOURNAL OF NEUROSCIENCE

Pindolol augmentation of serotonin reuptake inhibitors for the treatment of depressive disorder: a systematic review

(2008) R. Whale et al.   JOURNAL OF PSYCHOPHARMACOLOGY

Second-generation versus first-generation antipsychotic drugs for schizophrenia: a meta-analysis

(2008) Stefan Leucht et al.   LANCET

Evidence for HTR1A and LHPP as interacting genetic risk factors in major depression

(2008) C D Neff et al.   MOLECULAR PSYCHIATRY

Functional serotonin 1A receptor variant influences treatment response to atypical antipsychotics in schizophrenia

(2008) Rainald Mössner et al.   Pharmacogenetics and Genomics

Antipsychotics differ in their ability to internalise human dopamine D2S and human serotonin 5-HT1A receptors in HEK293 cells

(2007) Peter Heusler et al.   EUROPEAN JOURNAL OF PHARMACOLOGY