Article
Medicine, General & Internal
Tesfaye S. Mengistu, Veronika Schreiber, Christopher Flatley, Jane Fox, Sailesh Kumar
Summary: The study investigated maternal and intrapartum risk factors for early severe neonatal morbidity in late preterm and early term infants. Results identified risk factors such as pre-existing diabetes, instrumental birth, and emergency cesarean for late preterm infants, while pre-existing and gestational diabetes, antepartum hemorrhage, and certain birth methods were significant for early term infants. Overall, the predicted probability of early severe neonatal morbidity decreased with increasing gestational age.
JOURNAL OF CLINICAL MEDICINE
(2021)
Article
Obstetrics & Gynecology
Maria Andrikopoulou, Ukachi N. Emeruwa, Elizabeth Ludwig, Eve Overton, Cynthia Gyamfi-Bannerman
Summary: The study aimed to investigate the impact of race on respiratory morbidity in late preterm neonates, and the results showed that respiratory morbidity in late preterm infants is similar across different racial groups, and a history of pregnancies with neonatal respiratory disease is the strongest risk factor for respiratory disease recurrence.
AMERICAN JOURNAL OF OBSTETRICS & GYNECOLOGY MFM
(2021)
Article
Oncology
Francesco Petrella, Monica Casiraghi, Davide Radice, Claudia Bardoni, Andrea Cara, Shehab Mohamed, Daniele Sances, Lorenzo Spaggiari
Summary: This study evaluated the role and influencing factors of unplanned returns to the operating room (URORs) after elective oncologic thoracic surgery. The findings revealed that patients experiencing UROR after surgery had significantly higher morbidity and mortality rates, with bronchopleural fistula being the most lethal complication.
Article
Obstetrics & Gynecology
Cynthia Gyamfi-Bannerman, Angela B. Gantt, Russell S. Miller
Summary: The text highlights the established risks of late-preterm and early-term births, as well as the need to carefully consider maternal, fetal, and placental complications when determining delivery timing. It emphasizes the importance of delivering when there are clear indications for maternal or newborn benefits, regardless of lung maturity testing results, while also stressing the need for individualized delivery timing in certain conditions lacking data guidance.
OBSTETRICS AND GYNECOLOGY
(2021)
Article
Pediatrics
Haibo Peng, Yanling Shi, Fei Wang, Zhenchao Jin, Cungui Li, Jing Kang, Guofei Zhang, Lian Zhang, Yanli Yao, Zhangbin Yu
Summary: There are significant differences in obstetric and delivery room care practices and mortality and morbidity rates among very preterm infants between two representative tertiary newborn centers in northwestern and southern regions of China. Very preterm infants born in Qinghai Red Cross Hospital have higher odds of mortality or severe morbidity compared to those born in Shenzhen Baoan Women's and Children's Hospital.
Article
Pediatrics
Mathilde Letouzey, Elsa Lorthe, Laetitia Marchand-Martin, Gilles Kayem, Caroline Charlier, Marine Butin, Ayoub Mitha, Monique Kaminski, Valerie Benhammou, Pierre-Yves Ancel, Pascal Boileau, Laurence Foix-L'Helias
Summary: This study aims to assess the association between early empirical antibiotic therapy and adverse outcomes in very preterm infants. The study found that early antibiotic exposure was associated with an increased risk of severe cerebral lesions and moderate-severe bronchopulmonary dysplasia in very preterm infants at low risk of early-onset sepsis.
JOURNAL OF PEDIATRICS
(2022)
Article
Pediatrics
Qi Zhou, Edmond Kelly, Thuy Mai Luu, Xiang Y. Ye, Joseph Ting, Prakesh S. S. Shah, Shoo K. K. Lee
Summary: This study examined the incidence, mortality, short-term morbidity, and long-term neurodevelopmental outcomes of invasive fungal infection (IFI) among preterm infants in Canada. The study found that the incidence of IFI was 1.3%, and infants with IFI had higher mortality and adverse neurodevelopmental outcomes compared to those with non-fungal infections and no infections.
FRONTIERS IN PEDIATRICS
(2023)
Article
Surgery
Guy Ludbrook, Michael P. W. Grocott, Kathy Heyman, Sandy Clarke-Errey, Colin Royse, Jamie Sleigh, L. Bogdan Solomon
Summary: This study evaluated whether a new high-acuity postoperative unit, advanced recovery room care (ARRC), reduces complications and health care utilization compared with usual ward care (UC). The results showed that ARRC allowed enhanced detection and management of early medical emergency response (MER)-level complications, leading to a decrease in subsequent MER-level complications after discharge to the ward and an increase in days at home at 30 days.
Review
Pediatrics
Zeyar T. Htun, Jacqueline C. Hairston, Cynthia Gyamfi-Bannerman, Jaime Marasch, Ana Paula Duarte Ribeiro
Summary: Administering antenatal corticosteroids can help reduce respiratory morbidities in preterm and early term infants, but potential long term adverse effects should also be considered. Current practices of ACS use and discussions on extending versus restricting this practice to certain settings are important considerations.
Article
Obstetrics & Gynecology
Arpitha Chiruvolu, Kevin M. Claunch, Alberto J. Garcia, Barbara Petrey, Kendall Hammonds, Lea H. Mallett
Summary: The study revealed that in treating transient tachypnea of the newborn, using CPAP compared to NC resulted in significantly lower maximum FiO(2) levels in the CPAP group, with a 32% reduction in hours on oxygen.
JOURNAL OF PERINATOLOGY
(2021)
Article
Pediatrics
Nir Melamed, Omer Weitzner, Paige Church, Rudaina Banihani, Jon Barrett, Junmin Yang, Jonathan Wong, Bruno Piedboeuf, Prakesh S. Shah
Summary: This study compared the outcomes of preterm singleton and twin infants and found that twin infants born at 23-25 weeks, particularly those with same-sex and monochorionic pregnancies, had a higher risk of adverse neonatal outcomes and early-childhood outcomes compared to singleton infants.
JOURNAL OF PEDIATRICS
(2023)
Article
Obstetrics & Gynecology
Leilah D. Zahedi-Spung, Nandini Raghuraman, George A. Macones, Alison G. Cahill, Joshua Rosenbloom
Summary: Cesarean delivery for very preterm neonates may decrease the risk of death in the delivery room or within 24 hours post-delivery, but is not associated with an improvement in overall morbidity or mortality.
AMERICAN JOURNAL OF OBSTETRICS AND GYNECOLOGY
(2022)
Article
Pediatrics
Elizabeth G. Salazar, Sara C. Handley, Lucy T. Greenberg, Erika M. Edwards, Scott A. Lorch
Summary: This study analyzed 433,814 premature infants born in 465 US hospitals and found that the level of care in the neonatal intensive care unit (NICU) is associated with care quality for moderate and late preterm (MLP) infants but not for extremely and very preterm infants. MLP infants in type C NICUs had lower care quality scores. This study suggests that providing less complex subspecialty services in NICUs may improve the care quality for MLP infants.
Article
Pediatrics
Jie Chen, Yineng Zhou, Jie Tang, Chenyu Xu, Liping Chen, Biyun Xu, Yimin Dai, Yali Hu, Yi-Hua Zhou
Summary: This study aimed to investigate the role of breastfeeding and vaginal delivery in increasing mother-to-child transmission of cytomegalovirus (CMV) and to observe the clinical outcomes of postnatal infection in term or moderate and late preterm infants. The results showed that breastfeeding and vaginal delivery increased the risk of postnatal CMV infection, but did not affect the growth and liver function of the infants.
FRONTIERS IN PEDIATRICS
(2023)
Article
Pediatrics
Brendany Mulcahy, Daniel L. Rolnik, Alexia Matheson, Yizhen Liu, Kirsten R. Palmer, Ben W. Mol, Atul Malhotra
Summary: The study found that community lockdowns during the COVID-19 pandemic did not alter composite neonatal outcomes in preterm infants, but reduced rates of some common outcomes as well as early neonatal inflammatory markers in the exposed group.