Angiotensin-(1–7) and angiotensin-(1–9): function in cardiac and vascular remodelling

Relative affinity of angiotensin peptides and novel ligands at AT1and AT2receptors

(2015) Sanja Bosnyak et al.   CLINICAL SCIENCE

Angiotensin-(1–7) Dose-Dependently Inhibits Atherosclerotic Lesion Formation and Enhances Plaque Stability by Targeting Vascular Cells

(2013) Jian Min Yang et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

AVE 0991, a non-peptide mimic of angiotensin-(1-7) effects, attenuates pulmonary remodelling in a model of chronic asthma

(2013) M G Rodrigues-Machado et al.   BRITISH JOURNAL OF PHARMACOLOGY

Discovery and Characterization of Alamandine

(2013) Roberto Queiroga Lautner et al.   CIRCULATION RESEARCH

Loss of Angiotensin-Converting Enzyme-2 Exacerbates Diabetic Cardiovascular Complications and Leads to Systolic and Vascular Dysfunction

(2012) Vaibhav B. Patel et al.   CIRCULATION RESEARCH

Activation of the ACE2/Angiotensin-(1-7)/Mas Receptor Axis Enhances the Reparative Function of Dysfunctional Diabetic Endothelial Progenitors

(2012) Y. P. R. Jarajapu et al.   DIABETES

Cardioprotective Effects Mediated by Angiotensin II Type 1 Receptor Blockade and Enhancing Angiotensin 1-7 in Experimental Heart Failure in Angiotensin-Converting Enzyme 2–Null Mice

(2012) Vaibhav B. Patel et al.   HYPERTENSION

Angiotensin-Converting Enzyme 2 Priming Enhances the Function of Endothelial Progenitor Cells and Their Therapeutic Efficacy

(2012) Ji Chen et al.   HYPERTENSION

Hemodynamic effects of vasorelaxant compounds in mice lacking one, two or all three angiotensin II receptors

(2012) Florian Gembardt et al.   HYPERTENSION RESEARCH

Matrix control of transforming growth factor-  function

(2012) M. Horiguchi et al.   JOURNAL OF BIOCHEMISTRY

Regional mechanics determine collagen fiber structure in healing myocardial infarcts

(2012) Gregory M. Fomovsky et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

Myofibroblast-mediated mechanisms of pathological remodelling of the heart

(2012) Karl T. Weber et al.   Nature Reviews Cardiology

Angiotensin-(1–7) abrogates mitogen-stimulated proliferation of cardiac fibroblasts

(2012) LaTronya T. McCollum et al.   PEPTIDES

Angiotensin-(1-7) receptor Mas is an essential modulator of extracellular matrix protein expression in the heart

(2012) Elisandra Gava et al.   REGULATORY PEPTIDES

Renoprotective Effects of AVE0991, a Nonpeptide Mas Receptor Agonist, in Experimental Acute Renal Injury

(2012) Lívia Corrêa Barroso et al.   International Journal of Hypertension

AVE0991, a Nonpeptide Compound, Attenuates Angiotensin II-Induced Vascular Smooth Muscle Cell Proliferation via Induction of Heme Oxygenase-1 and Downregulation of p-38 MAPK Phosphorylation

(2012) Chen Sheng-Long et al.   International Journal of Hypertension

Endothelial Nox4 NADPH Oxidase Enhances Vasodilatation and Reduces Blood Pressure In Vivo

(2011) Robin Ray et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Chronic treatment with angiotensin-(1-7) improves renal endothelial dysfunction in apolipoproteinE-deficient mice

(2011) J Stegbauer et al.   BRITISH JOURNAL OF PHARMACOLOGY

An orally active formulation of angiotensin-(1-7) produces an antithrombotic effect

(2011) Rodrigo Araujo Fraga-Silva et al.   Clinics

Lentivirus-mediated overexpression of angiotensin-(1-7) attenuated ischaemia-induced cardiac pathophysiology

(2011) YanFei Qi et al.   EXPERIMENTAL PHYSIOLOGY

Angiotensin-(1-9) Attenuates Cardiac Fibrosis in the Stroke-Prone Spontaneously Hypertensive Rat via the Angiotensin Type 2 Receptor

(2011) Monica Flores-Munoz et al.   HYPERTENSION

Role of angiotensin-converting enzyme 2 in cardiac hypertrophy induced by nitric oxide synthase inhibition

(2011) Shinji Inaba et al.   JOURNAL OF HYPERTENSION

Rho kinase inhibition activates the homologous angiotensin-converting enzyme-angiotensin-(1–9) axis in experimental hypertension

(2011) María P Ocaranza et al.   JOURNAL OF HYPERTENSION

Differential Mechanisms of Ang (1-7)-Mediated Vasodepressor Effect in Adult and Aged Candesartan-Treated Rats

(2011) S. Bosnyak et al.   International Journal of Hypertension

Angiotensin-(1–7) upregulates cardiac nitric oxide synthase in spontaneously hypertensive rats

(2010) María A. Costa et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Vasoprotective and Atheroprotective Effects of Angiotensin (1-7) in Apolipoprotein E–Deficient Mice

(2010) Sonja Tesanovic et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Angiotensin-Converting Enzyme 2 Suppresses Pathological Hypertrophy, Myocardial Fibrosis, and Cardiac Dysfunction

(2010) JiuChang Zhong et al.   CIRCULATION

Circulating Rather Than Cardiac Angiotensin-(1-7) Stimulates Cardioprotection After Myocardial Infarction

(2010) Yong Wang et al.   Circulation-Heart Failure

Angiotensin-converting enzyme 2 activation protects against hypertension-induced cardiac fibrosis involving extracellular signal-regulated kinases

(2010) Anderson J. Ferreira et al.   EXPERIMENTAL PHYSIOLOGY

Angiotensin-(1–9) regulates cardiac hypertrophy in vivo and in vitro

(2010) Maria Paz Ocaranza et al.   JOURNAL OF HYPERTENSION

Angiotensin1-9 antagonises pro-hypertrophic signalling in cardiomyocytes via the angiotensin type 2 receptor

(2010) M. Flores-Muñoz et al.   JOURNAL OF PHYSIOLOGY-LONDON

Different Effects of Angiotensin II and Angiotensin-(1-7) on Vascular Smooth Muscle Cell Proliferation and Migration

(2010) Feng Zhang et al.   PLoS One

Angiotensin-(1–7) prevents atrial fibrosis and atrial fibrillation in long-term atrial tachycardia dogs

(2010) Enzhao Liu et al.   REGULATORY PEPTIDES

Chronic angiotensin-(1–7) administration improves vascular remodeling after angioplasty through the regulation of the TGF-β/Smad signaling pathway in rabbits

(2009) Wutao Zeng et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Angiotensin II–Mediated Adaptive and Maladaptive Remodeling of Cardiomyocyte Excitation–Contraction Coupling

(2009) Konstantin Gusev et al.   CIRCULATION RESEARCH

Loss of Angiotensin-Converting Enzyme 2 Accelerates Maladaptive Left Ventricular Remodeling in Response to Myocardial Infarction

(2009) Zamaneh Kassiri et al.   Circulation-Heart Failure

Onset of Experimental Severe Cardiac Fibrosis Is Mediated by Overexpression of Angiotensin-Converting Enzyme 2

(2009) Rachel Masson et al.   HYPERTENSION

Angiotensin-(1-7) Prevents Cardiomyocyte Pathological Remodeling Through a Nitric Oxide/Guanosine 3′,5′-Cyclic Monophosphate–Dependent Pathway

(2009) Enéas R.M. Gomes et al.   HYPERTENSION

Angiotensin II signaling via type 2 receptors in a human model of vascular hyporeactivity: implications for hypertension

(2009) Lorenzo A Calò et al.   JOURNAL OF HYPERTENSION

Alteration of sarcoplasmic reticulum Ca2+release termination by ryanodine receptor sensitization and in heart failure

(2009) Timothy L. Domeier et al.   JOURNAL OF PHYSIOLOGY-LONDON

Relationship between angiotensin-(1-7) and angiotensin II correlates with hemodynamic changes in human liver cirrhosis

(2009) Walkíria Wingester Vilas-Boas et al.   WORLD JOURNAL OF GASTROENTEROLOGY

Effect of Statins, Angiotensin-Converting Enzyme Inhibitors, and Beta Blockers on Survival in Patients ≥65 Years of Age With Heart Failure and Preserved Left Ventricular Systolic Function

(2008) Rahman Shah et al.   AMERICAN JOURNAL OF CARDIOLOGY

Angiotensin converting enzyme-2 confers endothelial protection and attenuates atherosclerosis

(2008) Fina Lovren et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Angiotensin(1-7) Blunts Hypertensive Cardiac Remodeling by a Direct Effect on the Heart

(2008) Chantal Mercure et al.   CIRCULATION RESEARCH

Molecular Mechanisms Involved in the Angiotensin-(1-7)/Mas Signaling Pathway in Cardiomyocytes

(2008) Marco F. Dias-Peixoto et al.   HYPERTENSION

Angiotensin-converting enzyme 2 (ACE2) expression and activity in human carotid atherosclerotic lesions

(2008) JC Sluimer et al.   JOURNAL OF PATHOLOGY

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(2008) Rodrigo Fraga-Silva et al.   MOLECULAR MEDICINE