Development of a mouse model mimicking key aspects of a viral asthma exacerbation

γδT cells suppress inflammation and disease during rhinovirus-induced asthma exacerbations

(2013) N Glanville et al.   Mucosal Immunology

The E3 ubiquitin ligase midline 1 promotes allergen and rhinovirus-induced asthma by inhibiting protein phosphatase 2A activity

(2013) Adam Collison et al.   NATURE MEDICINE

Macrophage/epithelial cell CCL2 contributes to rhinovirus-induced hyperresponsiveness and inflammation in a mouse model of allergic airways disease

(2012) Dina Schneider et al.   AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY

Safety and efficacy of a CXCR2 antagonist in patients with severe asthma and sputum neutrophils: a randomized, placebo-controlled clinical trial

(2012) P. Nair et al.   CLINICAL AND EXPERIMENTAL ALLERGY

IL-6 Induced by Double-Stranded RNA Augments Allergic Inflammation via Suppression of Foxp3+T-Cell/IL-10 Axis

(2011) Koichiro Matsumoto et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

Synthetic double-stranded RNA enhances airway inflammation and remodelling in a rat model of asthma

(2011) Satoshi Takayama et al.   IMMUNOLOGY

Asthma exacerbations: Origin, effect, and prevention

(2011) David J. Jackson et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Lebrikizumab Treatment in Adults with Asthma

(2011) Jonathan Corren et al.   NEW ENGLAND JOURNAL OF MEDICINE

MDA5 and TLR3 Initiate Pro-Inflammatory Signaling Pathways Leading to Rhinovirus-Induced Airways Inflammation and Hyperresponsiveness

(2011) Qiong Wang et al.   PLoS Pathogens

The Relationship of Airway Hyperresponsiveness and Airway Inflammation

(2010) William W. Busse   CHEST

Rhinovirus Infection of Allergen-Sensitized and -Challenged Mice Induces Eotaxin Release from Functionally Polarized Macrophages

(2010) D. R. Nagarkar et al.   JOURNAL OF IMMUNOLOGY

Treating Viral Exacerbations of Chronic Obstructive Pulmonary Disease: Insights from a Mouse Model of Cigarette Smoke and H1N1 Influenza Infection

(2010) Carla M. T. Bauer et al.   PLoS One

T-helper Type 2–driven Inflammation Defines Major Subphenotypes of Asthma

(2009) Prescott G. Woodruff et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Inhaled house dust mite induces pulmonary T helper 2 cytokine production

(2009) L. G. Gregory et al.   CLINICAL AND EXPERIMENTAL ALLERGY

SCH527123, a novel CXCR2 antagonist, inhibits ozone-induced neutrophilia in healthy subjects

(2009) O. Holz et al.   EUROPEAN RESPIRATORY JOURNAL

Molecular Mechanisms of Corticosteroid Resistance

(2008) Ian M. Adcock et al.   CHEST

Mouse models of rhinovirus-induced disease and exacerbation of allergic airway inflammation

(2008) Nathan W Bartlett et al.   NATURE MEDICINE

Rhinovirus-induced lower respiratory illness is increased in asthma and related to virus load and Th1/2 cytokine and IL-10 production

(2008) S. D. Message et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Anti-inflammatory modulation of chronic airway inflammation in the murine house dust mite model

(2008) Kristina Ulrich et al.   PULMONARY PHARMACOLOGY & THERAPEUTICS

The Synergistic Interactions of Allergic Lung Inflammation and Intratracheal Cationic Protein

(2007) Jason H. T. Bates et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE