Role of the CYP4A/20-HETE pathway in vascular dysfunction of the Dahl salt-sensitive rat

Introgression of Brown NorwayCYP4Agenes on to the Dahl salt-sensitive background restores vascular function in SS-5BNconsomic rats

(2012) Kathleen M. Lukaszewicz et al.   CLINICAL SCIENCE

Introgression of the Brown Norway Renin Allele Onto the Dahl Salt-Sensitive Genetic Background Increases Cu/Zn SOD Expression in Cerebral Arteries

(2011) M. J. Durand et al.   AMERICAN JOURNAL OF HYPERTENSION

Chronic activation of AMP-activated protein kinase prevents 20-hydroxyeicosatetraenoic acid-induced endothelial dysfunction

(2011) Natalie C Ward et al.   CLINICAL AND EXPERIMENTAL PHARMACOLOGY AND PHYSIOLOGY

Cytochrome P450 metabolites of arachidonic acid are elevated in stroke patients compared with healthy controls

(2011) Natalie C. Ward et al.   CLINICAL SCIENCE

Isolated Human and Rat Cerebral Arteries Constrict to Increases in Flow: Role of 20-HETE and TP Receptors

(2011) Peter Toth et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

20-HETE increases NADPH oxidase-derived ROS production and stimulates the L-type Ca2+ channel via a PKC-dependent mechanism in cardiomyocytes

(2010) Qinghua Zeng et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Impaired relaxation of cerebral arteries in the absence of elevated salt intake in normotensive congenic rats carrying the Dahl salt-sensitive renin gene

(2010) Matthew J. Durand et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

The Role of 20-Hydroxyeicosatetraenoic Acid in Cerebral Arteriolar Constriction and the Inhibitory Effect of Propofol

(2009) Keiko Hama-Tomioka et al.   ANESTHESIA AND ANALGESIA

20-Hydroxy-5,8,11,14-eicosatetraenoic Acid Mediates Endothelial Dysfunction via I B Kinase-Dependent Endothelial Nitric-Oxide Synthase Uncoupling

(2009) J. Cheng et al.   JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS

Oxidative Stress and Hypertension

(2009) David G. Harrison et al.   MEDICAL CLINICS OF NORTH AMERICA

Time-Course and Mechanisms of Restored Vascular Relaxation by Reduced Salt Intake and Angiotensin II Infusion in Rats Fed a High-Salt Diet

(2009) Scott T. McEwen et al.   MICROCIRCULATION

Modulation of Vascular O2Responses by Cytochrome 450-4A ω-Hydroxylase Metabolites In Dahl Salt-Sensitive Rats

(2009) Jingli Wang et al.   MICROCIRCULATION

A Single Nucleotide Polymorphism in the CYP4F2 but not CYP4A11 Gene Is Associated With Increased 20-HETE Excretion and Blood Pressure

(2008) Natalie C. Ward et al.   HYPERTENSION

Association of a Functional Cytochrome P450 4F2 Haplotype with Urinary 20-HETE and Hypertension

(2008) H. Liu et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Association of a CYP4A11 Variant and Blood Pressure in Black Men

(2008) J. V. Gainer et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

20-Hydroxyeicosatetraenoic acid causes endothelial dysfunction via eNOS uncoupling

(2007) Jennifer Cheng et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY