标题
IL-6/IL-6 receptor system and its role in physiological and pathological conditions
作者
关键词
-
出版物
CLINICAL SCIENCE
Volume 122, Issue 4, Pages 143-159
出版商
Portland Press Ltd.
发表日期
2011-10-14
DOI
10.1042/cs20110340
参考文献
相关参考文献
注意：仅列出部分参考文献，下载原文获取全部文献信息。- Regulation of IL-17 in Human CCR6+ Effector Memory T Cells
- (2014) H. Liu et al. JOURNAL OF IMMUNOLOGY
- IL-6 plays an essential role in neutrophilia under inflammation
- (2011) Misato Hashizume et al. CYTOKINE
- Anti-interleukin-6 receptor antibody, tocilizumab, for the treatment of autoimmune diseases
- (2011) Toshio Tanaka et al. FEBS LETTERS
- Tumor development in murine ulcerative colitis depends on MyD88 signaling of colonic F4/80+CD11bhighGr1low macrophages
- (2011) Gabriela Schiechl et al. JOURNAL OF CLINICAL INVESTIGATION
- Tocilizumab inhibits structural joint damage in rheumatoid arthritis patients with inadequate responses to methotrexate: Results from the double-blind treatment phase of a randomized placebo-controlled trial of tocilizumab safety and prevention of structu
- (2010) Joel M. Kremer et al. ARTHRITIS AND RHEUMATISM
- High molecular weight hyaluronic acid inhibits IL-6-induced MMP production from human chondrocytes by up-regulating the ERK inhibitor, MKP-1
- (2010) Misato Hashizume et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- Down-regulation of hepcidin resulting from long-term treatment with an anti-IL-6 receptor antibody (tocilizumab) improves anemia of inflammation in multicentric Castleman disease
- (2010) S.-N. J. Song et al. BLOOD
- Autostimulatory effects of IL-6 on excessive B cell differentiation in patients with systemic lupus erythematosus: analysis of IL-6 production and IL-6R expression
- (2010) A. KITANI et al. CLINICAL AND EXPERIMENTAL IMMUNOLOGY
- Immunologic abnormality in NZB/W Fl mice. Thymus-independent expansion of B cells responding to interleukin-6
- (2010) M. MIHARA et al. CLINICAL AND EXPERIMENTAL IMMUNOLOGY
- The acute phase protein response in patients receiving subcutaneous IL-6
- (2010) R. E. BANKS et al. CLINICAL AND EXPERIMENTAL IMMUNOLOGY
- Intercellular adhesion molecule-1 on synovial cells attenuated interleukin-6-induced inhibition of osteoclastogenesis induced by receptor activator for nuclear factor κB ligand
- (2010) M. Suzuki et al. CLINICAL AND EXPERIMENTAL IMMUNOLOGY
- Interleukin-6 as a Therapeutic Target in Candidate Inflammatory Diseases
- (2010) N Nishimoto CLINICAL PHARMACOLOGY & THERAPEUTICS
- IL-6 and IL-1 synergistically enhanced the production of MMPs from synovial cells by up-regulating IL-6 production and IL-1 receptor I expression
- (2010) Miho Suzuki et al. CYTOKINE
- Interleukin-6 in bone metastasis and cancer progression
- (2010) Tasnim Ara et al. EUROPEAN JOURNAL OF CANCER
- Anti-IL-6 receptor antibody suppressed T cell activation by inhibiting IL-2 production and inducing regulatory T cells
- (2010) Hiroto Yoshida et al. EUROPEAN JOURNAL OF PHARMACOLOGY
- Interleukin 6 as a Key Regulator of Muscle Mass during Cachexia
- (2010) James A. Carson et al. EXERCISE AND SPORT SCIENCES REVIEWS
- Comparative analysis of the effects of anti-IL-6 receptor mAb and anti-TNF mAb treatment on CD4+ T-cell responses in murine colitis
- (2010) Fumitaka Terabe et al. INFLAMMATORY BOWEL DISEASES
- Interleukin-6 and soluble interleukin-6 receptors in the synovial fluids from rheumatoid arthritis patients are responsible for osteoclast-like cell formation
- (2010) Shigeru Kotake et al. JOURNAL OF BONE AND MINERAL RESEARCH
- Lack of evidence for an increase in interleukin-6 expression in adult murine bone, bone marrow, and marrow stromal cell cultures after ovariectomy
- (2010) Socorro J. Vargas et al. JOURNAL OF BONE AND MINERAL RESEARCH
- Averting inflammation by targeting the cytokine environment
- (2010) Manfred Kopf et al. NATURE REVIEWS DRUG DISCOVERY
- Monitoring anti-interleukin 6 receptor antibody treatment for rheumatoid arthritis by quantitative magnetic resonance imaging of the hand and power Doppler ultrasonography of the finger
- (2010) Tamotsu Kamishima et al. SKELETAL RADIOLOGY
- Overproduced interleukin 6 decreases blood lipid levels via upregulation of very-low-density lipoprotein receptor
- (2009) M. Hashizume et al. ANNALS OF THE RHEUMATIC DISEASES
- Comparison of tocilizumab monotherapy versus methotrexate monotherapy in patients with moderate to severe rheumatoid arthritis: the AMBITION study
- (2009) G. Jones et al. ANNALS OF THE RHEUMATIC DISEASES
- Total cholesterol and LDL levels decrease before rheumatoid arthritis
- (2009) E. Myasoedova et al. ANNALS OF THE RHEUMATIC DISEASES
- Rapid improvement of AA amyloidosis with humanised anti-interleukin 6 receptor antibody treatment
- (2009) S Nishida et al. ANNALS OF THE RHEUMATIC DISEASES
- Rapid and sustained improvement in bone and cartilage turnover markers with the antiâinterleukin-6 receptor inhibitor tocilizumab plus methotrexate in rheumatoid arthritis patients with an inadequate response to methotrexate: Results from a substudy of the multicenter double-blind, placebo-controlled trial of tocilizumab in inadequate responders to methotrexate alone
- (2009) Patrick Garnero et al. ARTHRITIS AND RHEUMATISM
- IL-6 and Stat3 Are Required for Survival of Intestinal Epithelial Cells and Development of Colitis-Associated Cancer
- (2009) Sergei Grivennikov et al. CANCER CELL
- Recent developments and complexities in neutrophil transmigration
- (2009) Abigail Woodfin et al. CURRENT OPINION IN HEMATOLOGY
- Interleukin-6 inhibits early differentiation of ATDC5 chondrogenic progenitor cells
- (2009) Shoko Nakajima et al. CYTOKINE
- Molecular mechanisms of castration-resistant prostate cancer progression
- (2009) Smitha S Dutt et al. Future Oncology
- The induction of antibody production by IL-6 is indirectly mediated by IL-21 produced by CD4+T cells
- (2009) Oliver Dienz et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Proinflammatory Cytokines Synergistically Enhance the Production of Chemokine Ligand 20 (CCL20) from Rheumatoid Fibroblast-like Synovial Cells in vitro and Serum CCL20 Is Reduced in vivo by Biologic Disease-modifying Antirheumatic Drugs
- (2009) S.-Y. KAWASHIRI et al. JOURNAL OF RHEUMATOLOGY
- Properties and origin of human Th17 cells
- (2009) Sergio Romagnani et al. MOLECULAR IMMUNOLOGY
- B-cell-directed therapies for autoimmune disease
- (2009) Thomas Dörner et al. Nature Reviews Rheumatology
- Desirable effect of combination therapy with high molecular weight hyaluronate and NSAIDs on MMP production
- (2009) M. Hashizume et al. OSTEOARTHRITIS AND CARTILAGE
- Involvement of Th17 cells and the effect of anti-IL-6 therapy in autoimmune uveitis
- (2009) T. Yoshimura et al. RHEUMATOLOGY
- Tocilizumab, a humanized anti-interleukin-6 receptor antibody, improved anemia in monkey arthritis by suppressing IL-6-induced hepcidin production
- (2009) Misato Hashizume et al. RHEUMATOLOGY INTERNATIONAL
- IL-6/sIL-6R trans-signalling, but not TNF-α induced angiogenesis in a HUVEC and synovial cell co-culture system
- (2009) Misato Hashizume et al. RHEUMATOLOGY INTERNATIONAL
- Effects of the anti-interleukin-6 receptor antibody, tocilizumab, on serum lipid levels in patients with rheumatoid arthritis
- (2009) Shin-ya Kawashiri et al. RHEUMATOLOGY INTERNATIONAL
- Anti-inflammatory mechanism of tocilizumab, a humanized anti-IL-6R antibody: effect on the expression of chemokine and adhesion molecule
- (2009) Miho Suzuki et al. RHEUMATOLOGY INTERNATIONAL
- IL-6 receptor inhibition with tocilizumab improves treatment outcomes in patients with rheumatoid arthritis refractory to anti-tumour necrosis factor biologicals: results from a 24-week multicentre randomised placebo-controlled trial
- (2008) P. Emery et al. ANNALS OF THE RHEUMATIC DISEASES
- Interleukin-6 receptor inhibition with tocilizumab reduces disease activity in rheumatoid arthritis with inadequate response to disease-modifying antirheumatic drugs: The tocilizumab in combination with traditional disease-modifying antirheumatic drug therapy study
- (2008) Mark C. Genovese et al. ARTHRITIS AND RHEUMATISM
- Interleukin-6 blockade suppresses autoimmune arthritis in mice by the inhibition of inflammatory Th17 responses
- (2008) Minoru Fujimoto et al. ARTHRITIS AND RHEUMATISM
- Crucial role of the interleukin-6/interleukin-17 cytokine axis in the induction of arthritis by glucose-6-phosphate isomerase
- (2008) Keiichi Iwanami et al. ARTHRITIS AND RHEUMATISM
- Tocilizumab, a Humanized Anti-interleukin-6 Receptor Antibody, Ameliorates Joint Swelling in Established Monkey Collagen-Induced Arthritis
- (2008) Yasushi Uchiyama et al. BIOLOGICAL & PHARMACEUTICAL BULLETIN
- A key role for G-CSF-induced neutrophil production and trafficking during inflammatory arthritis
- (2008) J. L. Eyles et al. BLOOD
- Interleukin-6 in the Bone Marrow Microenvironment Promotes the Growth and Survival of Neuroblastoma Cells
- (2008) T. Ara et al. CANCER RESEARCH
- Interleukin-6 Directly Inhibits Osteoclast Differentiation by Suppressing Receptor Activator of NF-κB Signaling Pathways
- (2008) Fumio Yoshitake et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Cachexia Worsens Prognosis in Patients with Resectable Pancreatic Cancer
- (2008) Jeannine Bachmann et al. JOURNAL OF GASTROINTESTINAL SURGERY
- Effect of interleukin-6 receptor inhibition with tocilizumab in patients with rheumatoid arthritis (OPTION study): a double-blind, placebo-controlled, randomised trial
- (2008) Josef S Smolen et al. LANCET
- Efficacy and safety of tocilizumab in patients with systemic-onset juvenile idiopathic arthritis: a randomised, double-blind, placebo-controlled, withdrawal phase III trial
- (2008) Shumpei Yokota et al. LANCET
- Study of active controlled tocilizumab monotherapy for rheumatoid arthritis patients with an inadequate response to methotrexate (SATORI): significant reduction in disease activity and serum vascular endothelial growth factor by IL-6 receptor inhibition therapy
- (2008) Norihiro Nishimoto et al. Modern Rheumatology
- IL-6 blockade inhibits the induction of myelin antigen-specific Th17 cells and Th1 cells in experimental autoimmune encephalomyelitis
- (2008) Satoshi Serada et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- IL-6 trans-signalling directly induces RANKL on fibroblast-like synovial cells and is involved in RANKL induction by TNF- and IL-17
- (2008) M. Hashizume et al. RHEUMATOLOGY
- Anemia in monkey collagen-induced arthritis is correlated with serum IL-6, but not TNFα
- (2008) Yasushi Uchiyama et al. RHEUMATOLOGY INTERNATIONAL
- Influence of humanized anti-IL-6R antibody, tocilizumab on the activity of soluble gp130, natural inhibitor of IL-6 signaling
- (2008) Misato Hashizume et al. RHEUMATOLOGY INTERNATIONAL
Create your own webinar
Interested in hosting your own webinar? Check the schedule and propose your idea to the Peeref Content Team.
Create NowBecome a Peeref-certified reviewer
The Peeref Institute provides free reviewer training that teaches the core competencies of the academic peer review process.
Get Started