Sitagliptin prevents the development of metabolic and hormonal disturbances, increased β-cell apoptosis and liver steatosis induced by a fructose-rich diet in normal rats

Antihyperglycemic effects of ASP8497 in streptozotocin-nicotinamide induced diabetic rats: comparison with other dipeptidyl peptidase-IV inhibitors

(2014) Atsuo Tahara et al.   Pharmacological Reports

Effects of Sitagliptin Treatment on Dysmetabolism, Inflammation, and Oxidative Stress in an Animal Model of Type 2 Diabetes (ZDF Rat)

(2010) Liliana Ferreira et al.   MEDIATORS OF INFLAMMATION

Regulation of liver glucokinase activity in rats with fructose-induced insulin resistance and impaired glucose and lipid metabolism

(2009) Flavio Francini et al.   CANADIAN JOURNAL OF PHYSIOLOGY AND PHARMACOLOGY

Combination treatment with alogliptin and voglibose increases active GLP-1 circulation, prevents the development of diabetes and preserves pancreatic beta-cells in prediabeticdb/dbmice

(2009) Y. Moritoh et al.   DIABETES OBESITY & METABOLISM

The beta cell lesion in type 2 diabetes: there has to be a primary functional abnormality

(2009) S. E. Kahn et al.   DIABETOLOGIA

Inhibition of DPP-4 with sitagliptin improves glycemic control and restores islet cell mass and function in a rodent model of type 2 diabetes

(2009) James Mu et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Differential Importance of Glucose-Dependent Insulinotropic Polypeptide vs Glucagon-Like Peptide 1 Receptor Signaling for Beta Cell Survival in Mice

(2009) Adriano Maida et al.   GASTROENTEROLOGY

GLP-1 receptor signaling protects pancreatic beta cells in intraportal islet transplant by inhibiting apoptosis

(2008) Kentaro Toyoda et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Glucolipotoxicity: Fuel Excess and β-Cell Dysfunction

(2008) Vincent Poitout et al.   ENDOCRINE REVIEWS

The dipeptidyl peptidase-4 inhibitor alogliptin in combination with pioglitazone improves glycemic control, lipid profiles, and increases pancreatic insulin content in ob/ob mice

(2008) Yusuke Moritoh et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Abdominal Adipose Tissue: Early Metabolic Dysfunction Associated to Insulin Resistance and Oxidative Stress Induced by an Unbalanced Diet

(2008) O. Rebolledo et al.   HORMONE AND METABOLIC RESEARCH

Islet adaptive changes to fructose-induced insulin resistance: β-cell mass, glucokinase, glucose metabolism, and insulin secretion

(2008) B Maiztegui et al.   JOURNAL OF ENDOCRINOLOGY

The incretin system and its role in type 2 diabetes mellitus

(2008) J HOLST et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

Efficacy of the dipeptidyl peptidase IV inhibitor isoleucine thiazolidide (P32/98) in fatty Zucker rats with incipient and manifest impaired glucose tolerance

(2007) P. Augstein et al.   DIABETES OBESITY & METABOLISM