α1-Antitrypsin deficiency, chronic obstructive pulmonary disease and the serpinopathies

Crystallographic and Cellular Characterisation of Two Mechanisms Stabilising the Native Fold of α1-Antitrypsin: Implications for Disease and Drug Design

(2009) Bibek Gooptu et al.   JOURNAL OF MOLECULAR BIOLOGY

The intracellular accumulation of polymeric neuroserpin explains the severity of the dementia FENIB

(2008) E. Miranda et al.   HUMAN MOLECULAR GENETICS

The molecular aetiology of the serpinopathies

(2008) M DAVIES et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

Polymers and inflammation: disease mechanisms of the serpinopathies

(2008) Bibek Gooptu et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Crystal structure of a stable dimer reveals the molecular basis of serpin polymerization

(2008) Masayuki Yamasaki et al.   NATURE

NEUROSERPIN MUTATION CAUSES ELECTRICAL STATUS EPILEPTICUS OF SLOW-WAVE SLEEP

(2008) M. Coutelier et al.   NEUROLOGY

Dimers Initiate and Propagate Serine Protease Inhibitor Polymerisation

(2007) Aiwu Zhou et al.   JOURNAL OF MOLECULAR BIOLOGY

Cavities of α1-antitrypsin that play structural and functional roles

(2002) Cheolju Lee et al.   PROTEIN SCIENCE