Article
Rehabilitation
Sarah R. Robbins, Patricia P. Alfredo, Washington S. Junior, Amelia P. Marques
Summary: The study aimed to investigate the effect of laser therapy combined with stretching exercises on pain and functionality in patients with knee osteoarthritis. The results showed significant improvements in pain relief, activity levels, and range of motion in the knee joint.
CLINICAL REHABILITATION
(2022)
Article
Rehabilitation
Patricia Pereira Alfredo, Jan Magnus Bjordal, Rodrigo Alvaro Brandao Lopes-Martins, Mark Johnson, Washington Steagall Junior, Amelia Pasqual Marques, Raquel Aparecida Casarotto
Summary: This study investigated the effect of prolonged low-level laser therapy combined with exercise on pain and disability in patients with knee osteoarthritis. The results showed that the isolated application of low-level laser therapy in the initial 3 weeks and combined with exercises in the final 8 weeks reduced pain, disability, and medication intake over a 6-month period.
CLINICAL REHABILITATION
(2022)
Article
Medicine, General & Internal
Martin Bjorn Stausholm, Ingvill Fjell Naterstad, Patricia Pereira Alfredo, Christian Couppe, Kjartan Vibe Fersum, Ernesto Cesar Pinto Leal-Junior, Rodrigo Alvaro Brandao Lopes-Martins, Jon Joensen, Jan Magnus Bjordal
Summary: LLT combined with strength training can reduce pain and improve physical performance in patients with knee osteoarthritis. However, the improvement in joint line pain pressure threshold is less significant compared to placebo therapy.
JOURNAL OF CLINICAL MEDICINE
(2022)
Review
Engineering, Biomedical
Roberta Chow, Ann Liebert, Sharon Tilley, Gregory Bennett, C. Philip Gabel, Liisa Laakso
Summary: This review analyzed the Australian Guideline for the treatment of knee osteoarthritis developed using GRADE methodology, which recommended against the use of low-level laser therapy (LLLT). However, the latest systematic review provided strong support for LLLT, highlighting a conflict between guidelines based on opinion and evidence. It is recommended that the Australian Guideline should be updated immediately to reflect a positive recommendation.
LASERS IN MEDICAL SCIENCE
(2021)
Article
Rehabilitation
Bugra Ince, Altinay Goksel Karatepe, Seniz Akcay, Taciser Kaya
Summary: This study aimed to investigate the effects of balance and proprioception exercises in patients with knee osteoarthritis. The results showed that balance and proprioception exercises may have positive effects on dynamic balance and pain. However, further studies are needed to examine the effects on physical function and quality of life.
CLINICAL REHABILITATION
(2023)
Article
Rheumatology
Soheir Shehata RezkAllah Rezk Samaan, Magda G. Sedhom, Mariam O. Grace
Summary: This study compared the effects of high-intensity laser therapy (HILT) plus exercise therapy (ET) and low-intensity pulsed ultrasound (LIPUS) plus ET on knee osteoarthritis (KOA). The results showed that HILT+ET achieved better improvement in pain, knee ROM, proprioceptive accuracy, and functional disability compared to LIPUS+ET and ET alone.
INTERNATIONAL JOURNAL OF RHEUMATIC DISEASES
(2022)
Article
Medicine, General & Internal
Sihong Li, Min Yang, Long Tang, Yizhao Zhou
Summary: This study aims to evaluate the synergistic effects of ultrasound and low-level laser therapy in patients with knee osteoarthritis through a randomized double-blind design, providing a reliable theoretical basis for future research. The results are expected to have a significant impact on postoperative outcomes for patients.
Review
Rehabilitation
Mohd Azzuan Ahmad, Mohamad Shariff A. Hamid, Ashril Yusof
Summary: This study examined the effects of low-level laser therapy (LLLT) and high-intensity laser therapy (HILT) combined with rehabilitation exercise on pain, stiffness, and function in knee osteoarthritis (KOA). The results showed that both LLLT and HILT were effective in reducing KOA symptoms, with HILT showing greater efficacy in reducing knee pain and stiffness.
Review
Engineering, Biomedical
Xiaojie Lin, Ching Ting Tsao, Masayuki Kyomoto, Miqin Zhang
Summary: Osteoarthritis (OA) is a prevalent chronic disease in the elderly population, with current clinical treatments limited to symptom relief. Injectable natural polymer hydrogels are considered highly promising for controlled drug delivery.
ADVANCED HEALTHCARE MATERIALS
(2022)
Article
Biology
Mohd Azzuan Ahmad, Mageswari Moganan, Mohamad Shariff Hamid, Norhuda Sulaiman, Ushantini Moorthy, Nazirah Hasnan, Ashril Yusof
Summary: This study aimed to compare the effects of low-level laser therapy (LLLT) and high-intensity laser therapy (HILT) as adjuncts to knee osteoarthritis (KOA) rehabilitation exercises. The results showed that compared to LLLT, HILT led to significant improvements in pain, physical function, and knee-related disability.
Article
Veterinary Sciences
Loris Barale, Paolo Monticelli, Chiara Adami
Summary: Low-level laser therapy (LLLT) can increase physical activity in dogs with osteoarthritis, thus improving their quality of life.
VETERINARY MEDICINE AND SCIENCE
(2023)
Article
Rehabilitation
Eng Chuan Neoh, Matthew Rong Jie Tay, Jaclyn Tan, Joshua Tan, Ying Tong Lim, Acharyya Sanchalika, Ling Fong Chong, Kelvin Guoping Tan
Summary: The study found that patients who received additional rehabilitative exercises supervised by peer volunteers after TKA showed improved knee flexion ROM at discharge. However, there were no significant differences between the intervention and control group in other rehabilitation outcomes.
ARCHIVES OF PHYSICAL MEDICINE AND REHABILITATION
(2021)
Article
Medicine, General & Internal
Sameer Akram Gohir, Frida Eek, Anthony Kelly, Abhishek Abhishek, Ana M. Valdes
Summary: The study showed that internet-based treatment for knee osteoarthritis was more effective than routine self-management care, without causing harm to arthritis patients. The intervention group experienced significant improvements in pain relief, physical function, and muscle strength compared to the control group.
Article
Integrative & Complementary Medicine
Chiung-Hui Huang, Mei-Ling Yeh, Fang-Pey Chen, Daphne Wu
Summary: This study aimed to evaluate the effect of low-level laser acupuncture on postoperative pain in older patients with knee osteoarthritis after total knee arthroplasty. The results showed that low-level laser acupuncture can gradually reduce postoperative pain intensity and morphine consumption in these patients.
JOURNAL OF INTEGRATIVE MEDICINE-JIM
(2022)
Article
Geriatrics & Gerontology
Michal Elboim-Gabyzon, Fouad Nahhas
Summary: This randomized controlled trial found that both pulsed electromagnetic field therapy (PEMFT) and low-level laser therapy (LLLT) have significant positive effects on pain and physical function in individuals with knee osteoarthritis (KOA), with PEMFT showing better results.
Article
Rheumatology
Sarah R. Robbins, Luciano R. S. Melo, Hema Urban, Leticia A. Deveza, Rebecca Asher, Victoria L. Johnson, David J. Hunter
Summary: The study aimed to test the effectiveness of a 32-week, stepped-care intervention on disease remission rates in overweight and obese patients with medial tibiofemoral osteoarthritis. Results showed a slightly higher disease remission rate in the stepped-care group compared to the control group, but no significant difference was found.
ARTHRITIS CARE & RESEARCH
(2021)
Article
Neurosciences
Fabrizio dos Santos Cardoso, Julio Cesar Claudino dos Santos, Francisco Gonzalez-Lima, Bruno Henrique Silva Araujo, Rodrigo Alvaro Brandao Lopes-Martins, Sergio Gomes da Silva
Summary: The study found that transcranial photobiomodulation can enhance brain energy metabolism and cognition, particularly reversing aging-related metabolic changes in older rats. Statistical analysis revealed that photobiomodulation significantly improved metabolic pathways in younger rats, especially in excitatory neurotransmission and oxidative metabolism, while restoring altered pathways in older rats.
MOLECULAR NEUROBIOLOGY
(2021)
Article
Cell Biology
Fabrizio dos Santos Cardoso, Cristiane de Souza Oliveira Tavares, Bruno Henrique Silva Araujo, Fernanda Mansur, Rodrigo Alvaro Brandao Lopes-Martins, Sergio Gomes da Silva
Summary: Transcranial photobiomodulation improves spatial learning and memory in young and aged rats, while also altering their neuroinflammatory profile.
CELLULAR AND MOLECULAR NEUROBIOLOGY
(2022)
Article
Orthopedics
X. Liu, S. Robbins, J. Eyles, T. Fedorova, S. Virk, L. A. Deveza, A. J. McLachlan, D. J. Hunter
Summary: The RADIANT study aimed to investigate the efficacy and safety of a complementary medicine supplement combination in people with hand osteoarthritis. However, the results showed no significant differences in symptomatic relief between the two groups over 12 weeks, suggesting that the supplement combination might not be effective for treating hand pain in people with HOA.
OSTEOARTHRITIS AND CARTILAGE
(2021)
Article
Biochemical Research Methods
Rafael Campos, David Halen Araujo Pinheiro, Jose Britto-Junior, Heleson Alves de Castro, Gustavo Duarte Mendes, Manoel Odorico Moraes, Maria Elisabete A. Moraes, Rodrigo Alvaro Brandao Lopes-Martins, Natalicia J. Antunes, Gilberto De Nucci
Summary: This study describes the development and validation of a method for quantification of 6-nitrodopamine in Krebs-Henseleit's solution using LC-MS/MS technology. The results indicate that tortoise aortae display a basal endothelium-derived 6-nitrodopamine release, with mean concentrations of 0.44 +/- 0.06 ng/mL and 0.18 +/- 0.05 ng/mL for endothelium-intact and denuded aortae, respectively.
JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES
(2021)
Article
Orthopedics
Vicky Duong, Philippa J. A. Nicolson, Sarah R. Robbins, Leticia A. Deveza, Anne Wajon, Ray Jongs, David J. Hunter
Summary: This study aimed to determine whether baseline pain and hand function were associated with treatment adherence in participants with thumb base OA over 12 weeks. The results showed that high baseline pain was significantly associated with better treatment adherence, while higher baseline functional impairment was not.
JOURNAL OF HAND THERAPY
(2022)
Article
Chemistry, Physical
Luis Vicente Franco Oliveira, Nadua Apostolico, Juan Jose Uriarte, Renata Kelly da Palma, Renato A. Prates, Alessandro Melo Deana, Luis Rodolfo Ferreira, Joao Pedro Ribeiro Afonso, Rodolfo de Paula Vieira, Manoel Carneiro de Oliveira Junior, Daniel Navajas, Ramon Farre, Rodrigo Alvaro B. Lopes-Martins
Summary: The study aimed to evaluate the extracellular matrix and lung mechanical parameters of decellularized lungs undergoing sterilizing photodynamic therapy, showing no significant changes in lung properties after PDT and a reduction in fungal infection population following PDT. Further studies are needed to confirm the effectiveness of PDT in sterilizing lung scaffolds.
INTERNATIONAL JOURNAL OF PHOTOENERGY
(2021)
Article
Engineering, Biomedical
Sadi Fernando Stamborowski, Bruna Moreira de Oliveira Spinelli, Fernanda Pupio Silva Lima, Davidson Ribeiro Costa, Gabriela Aparecida de Silveira Souza, Mario Oliveira Lima, Rodrigo Alvaro Brandao Lopes Martins
Summary: The study found that low-level laser therapy can alleviate muscle fatigue and have a positive effect on body thermoregulation. A crossover study revealed that the laser group showed a lower rate of muscle strength decrease during the muscle fatigue protocol.
LASERS IN MEDICAL SCIENCE
(2021)
Article
Orthopedics
L. A. Deveza, S. R. Robbins, V. Duong, K. Fu, A. Wajon, J. P. Eyles, R. Jongs, E. A. Riordan, W. M. Oo, D. J. Hunter
Summary: The study investigated heterogeneous effects of a combination of conservative therapies compared with an education intervention for thumb base osteoarthritis. Results showed that the combined intervention had greater benefits in patients with lower joint subluxation, with no significant heterogeneity in other subgroups. Customized treatment strategies may be necessary based on individual characteristics.
OSTEOARTHRITIS AND CARTILAGE
(2021)
Article
Rehabilitation
Sarah R. Robbins, Patricia P. Alfredo, Washington S. Junior, Amelia P. Marques
Summary: The study aimed to investigate the effect of laser therapy combined with stretching exercises on pain and functionality in patients with knee osteoarthritis. The results showed significant improvements in pain relief, activity levels, and range of motion in the knee joint.
CLINICAL REHABILITATION
(2022)
Article
Rheumatology
Ying Shi, Kai Fu, Win Min Oo, Leticia A. Deveza, Xia Wang, Vicky Duong, Sarah R. Robbins, David J. Hunter
Summary: This study reveals a significant correlation between radiographic features and hand function in thumb-base osteoarthritis, while ultrasound-detected PDS is closely related to the PGA at baseline. Additionally, radiographic JSN may serve as a predictor for stiffness and PGA in thumb-base osteoarthritis.
INTERNATIONAL JOURNAL OF RHEUMATIC DISEASES
(2022)
Article
Rehabilitation
Patricia Pereira Alfredo, Jan Magnus Bjordal, Rodrigo Alvaro Brandao Lopes-Martins, Mark Johnson, Washington Steagall Junior, Amelia Pasqual Marques, Raquel Aparecida Casarotto
Summary: This study investigated the effect of prolonged low-level laser therapy combined with exercise on pain and disability in patients with knee osteoarthritis. The results showed that the isolated application of low-level laser therapy in the initial 3 weeks and combined with exercises in the final 8 weeks reduced pain, disability, and medication intake over a 6-month period.
CLINICAL REHABILITATION
(2022)
Article
Multidisciplinary Sciences
Ana Maria Braga de Oliveira, Doralice Severo da Cruz Teixeira, Fabricio dos Santos Menezes, Amelia Pasqual Marques, Yeda Aparecida de Oliveira Duarte, Raquel Aparecida Casarotto
Summary: In this study, the impact of socioeconomic inequalities on chronic pain in older adults was investigated, focusing on sex differences. The study found that chronic pain was more common in females (27.2%) than in males (14.5%). Socioeconomic factors such as poverty and race had a greater impact on chronic pain in females, while in males, educational attainment and insufficient income were significant factors.
Article
Biochemical Research Methods
Martin Bjorn Stausholm, Ingvill Fjell Naterstad, Christian Couppe, Kjartan Vibe Fersum, Ernesto Cesar Pinto Leal-Junior, Rodrigo alvaro Brandao Lopes-Martins, Jan Magnus Bjordal, Jon Joensen
Summary: This study investigates the long-term effectiveness of LLLT combined with ST in persons with KOA, focusing on pain reduction, disability level, quality-of-life, and physical abilities. The results will improve understanding of the pathophysiology, tissue morphology, and clinical status of KOA patients up to a year after starting ST and receiving a higher 904 nm LLLT dose.
METHODS AND PROTOCOLS
(2021)
Article
Rehabilitation
Rose Goonan, Edward Mohandoss, Celia Marston, Jaqueline Kay, Anurika Priyanjali De Silva, Andrea B. Maier, Esmee Reijnierse, Marlena Klaic
Summary: This study evaluated the physical and functional outcomes of the 'Ending Pyjama Paralysis' intervention in geriatric rehabilitation patients. The results showed that this intervention did not lead to additional functional and physical benefits in this setting.
CLINICAL REHABILITATION
(2024)
Article
Rehabilitation
Sinikka Kilpikoski, Arja H. Hakkinen, Jussi P. Repo, Kati Kyrola, Juhani Multanen, Markku Kankaanpaa, Aki Vainionpaa, Esa-Pekka Takala, Hannu Kautiainen, Jari Ylinen
Summary: This study aimed to compare the effectiveness of a McKenzie Method intervention with guideline-based patient education in patients with sciatica. The results showed that multiple sessions of McKenzie-based back exercises combined with a patient's educational book had similar long-term effects to guideline-based advice. However, the small sample size and confounding factors limited the power of these results.
CLINICAL REHABILITATION
(2024)
Article
Rehabilitation
Margot W. M. de Waal, Michael Jansen, Loes M. Bakker, Arno J. Doornebosch, Elizabeth M. Wattel, Dennis Visser, Ewout B. Smit
Summary: The Utrecht Scale for Evaluation of Rehabilitation has been shown to be effective in evaluating physical and cognitive functioning in geriatric rehabilitation. A minimal important change of 14.5 points has been established for physical functioning.
CLINICAL REHABILITATION
(2024)