Article
Urology & Nephrology
Jianli Yang, Qiaozhi Ma, Jiqiang Liu, Haiping Zu, Siqing Dong, Ying Liu, Gang Guo, Binbin Nie, Xuetao Mu
Summary: The study aimed to investigate the application of multiparametric MRI in evaluating the correlation between transitional zone characteristics and IPSS in BPH patients. The results showed that mp-MRI could effectively assess the volume and morphology of BPH, with mean-SI-T2WI and ADC being able to describe the internal composition of the prostate.
Article
Oncology
Angeles Garcia-Criado, Jordi Rimola, Susana Seijo, Anna Darnell, Ernest Belmonte, Victor Sapena, Julian Moreno-Rojas, Valeria Perez, Virginia Hernandez-Gea, Carmen Ayuso, Maria Reig, Juan Carlos Garcia-Pagan, Jordi Bruix
Summary: This study evaluates the incidence of hepatocellular carcinoma (HCC) in Western patients with Budd-Chiari syndrome (BCS) and assesses the performance of MRI with hepatobiliary contrast (HB-MRI) for nodule characterization. A total of 55 nodules with arterial phase hyperenhancement (APHE) were detected at EC-MRI, but HCC was not detected during a median of 10 years of follow-up. HB-MRI with contrast uptake in the hepatobiliary phase may help to categorize nodules as benign.
Article
Urology & Nephrology
Jessica C. Dai, Tara N. Morgan, Ramy Goueli, Daniel Parrott, Alexander Kenigsberg, Ryan J. Mauck, Claus G. Roehrborn, Douglas W. Strand, Daniel N. Costa, Jeffrey C. Gahan
Summary: The study found a strong correlation between MRI features and the histologic phenotype of BPH nodules, suggesting that MRI may provide a noninvasive method to determine underlying BPH nodule histology.
JOURNAL OF ENDOUROLOGY
(2022)
Article
Radiology, Nuclear Medicine & Medical Imaging
Daniel N. Costa, Liwei Jia, Naveen Subramanian, Yin Xi, Neil M. Rofsky, Debora Z. Recchimuzzi, Alberto Diaz de Leon, Patrick Arraj, Ivan Pedrosa
Summary: This study compared the detection rates of clinically significant prostate cancer in prospectively reported 2 + 1 TZ lesions and conventional 3 + 0 TZ lesions defined by PI-RADS v2.1, finding no significant difference in cancer detection rates between the two groups.
AMERICAN JOURNAL OF ROENTGENOLOGY
(2021)
Article
Radiology, Nuclear Medicine & Medical Imaging
Mengsi Li, Jing Guo, Ping Hu, Huichuan Jiang, Juan Chen, Jiaxi Hu, Patrick Asbach, Ingolf Sack, Wenzheng Li
Summary: The study investigated the diagnostic performance of stiffness and fluidity quantified with tomoelastography compared to multiparametric MRI in depicting prostate cancer. The results showed that combining stiffness and fluidity improved the diagnostic performance of detecting PCa, demonstrating higher specificity and better differentiation in both the peripheral and transition zones.
Article
Oncology
Han Xu, Ximing Wang, Chaoqun Guan, Ru Tan, Qing Yang, Qi Zhang, Aie Liu, Qingwei Liu
Summary: The objective of this research is to explore the value of whole-thyroid CT-based radiomics in predicting benign and malignant thyroid nodules. A highly efficient CT radiomic model was constructed to differentiate between the two types of nodules based on the analysis of imaging and clinical data.
FRONTIERS IN ONCOLOGY
(2022)
Article
Radiology, Nuclear Medicine & Medical Imaging
Hesong Shen, Xiaoqian Yuan, Daihong Liu, Chunrong Tu, Xing Wang, Renwei Liu, Xiaoxia Wang, Xiaosong Lan, Kaiwen Fu, Jiuquan Zhang
Summary: The study aimed to differentiate between NPCT1 and BH using DECT-derived virtual monoenergetic images, with 40 keV VMI(+) showing better demarcation, quality, and contrast effects in the enhanced phase. The combination of image features and quantitative parameters resulted in effective differentiation between the two diseases, with high sensitivity and specificity.
QUANTITATIVE IMAGING IN MEDICINE AND SURGERY
(2021)
Article
Multidisciplinary Sciences
Stephan Ursprung, Andrew N. Priest, Fulvio Zaccagna, Wendi Qian, Andrea Machin, Grant D. Stewart, Anne Y. Warren, Timothy Eisen, Sarah J. Welsh, Ferdia A. Gallagher, Tristan Barrett
Summary: The study aimed to detect early response to sunitinib treatment in metastatic clear cell renal cancer using multiparametric MRI. The results showed a reduction in tumor volumes and improved diffusivity after 12 days of sunitinib therapy, with correlations to treatment response and progression-free survival. Physiological imaging confirmed efficacy of the anti-angiogenic agent and demonstrated response to treatment shortly after initiation.
Review
Radiology, Nuclear Medicine & Medical Imaging
Teresa A. Diaz, Benjamin Benson, Alexander Clinkenbeard, Jeremiah R. Long, Akira Kawashima, Motoyo Yano
Summary: There are various minimally invasive surgical therapies available for the treatment of benign prostatic hyperplasia (BPH), including laser-based and thermal ablation procedures, which result in volume reduction of prostatic tissue. While MRI is not commonly used in the routine preprocedural evaluation of BPH, emerging data suggest a potential role for MRI in predicting postprocedure outcomes.
AMERICAN JOURNAL OF ROENTGENOLOGY
(2022)
Article
Oncology
Yanjie Zhao, Rong Chen, Ting Zhang, Chaoyue Chen, Muhetaer Muhelisa, Jingting Huang, Yan Xu, Xuelei Ma
Summary: This study suggests that a combination of MRI texture analysis and LDA algorithm is effective in discriminating between benign and malignant breast lesions. Different classification models showed promising results in both training and validation groups, demonstrating potential clinical utility.
FRONTIERS IN ONCOLOGY
(2021)
Article
Oncology
Rongqi Yi, Ting Li, Gang Xie, Kang Li
Summary: A DLCT-based nomogram was developed and tested for the preoperative classification of benign and malignant thyroid nodules. The nomogram showed good diagnostic performance and can serve as a simple and effective tool for individualized risk assessment and treatment decision-making.
FRONTIERS IN ONCOLOGY
(2023)
Article
Medicine, General & Internal
Vanessa F. Schmidt, Mirjam Schirren, Maurice M. Heimer, Philipp M. Kazmierczak, Clemens C. Cyran, Moritz Wildgruber, Max Seidensticker, Jens Ricke, Olga Solyanik
Summary: This study assessed the treatment response of BPS patients following PAE using a semi-automatic software analysis of MRI features and clinical indexes. The results showed a significant reduction in TGV after PAE, with CGV decreasing significantly after one month. Improvement in IPSS and ICIQ-UI SF after one month correlated moderately with TGV reduction.
Article
Radiology, Nuclear Medicine & Medical Imaging
Siqian Gu, Jing Qian, Ling Yang, Zhilei Sun, Chunhong Hu, Ximing Wang, Su Hu, Yuyang Xie
Summary: A radiomics-clinical model and nomogram were developed to differentiate between brain glial cell hyperplasia and low-grade glioma using multiparametric MRI imaging and clinical risk factors.
BMC MEDICAL IMAGING
(2023)
Article
Radiology, Nuclear Medicine & Medical Imaging
Thomas H. Sanford, Stephanie A. Harmon, Deepak Kesani, Sandeep Gurram, Nikhil Gupta, Sherif Mehralivand, Jonathan Sackett, Scott Wiener, Bradford J. Wood, Sheng Xu, Peter A. Pinto, Peter L. Choyke, Baris Turkbey
Summary: The study aimed to quantitatively assess prostate anatomy and its relation to lower urinary tract symptoms. Prostatic urethral length was found to be associated with worse urinary symptoms, along with urethral angle and transition zone volume. This demonstrates the potential of quantitative assessment of prostatic urethral anatomy in predicting lower urinary tract symptoms.
ACADEMIC RADIOLOGY
(2021)
Article
Medicine, General & Internal
Ying Cao, Heng Zhang, Gui-Lan Tu, Ye Tian, Xiao-Hu Tang, Lei Tang, Mu-Xia Luo, Yan-Dong Wang, Zhen Wang, Shu-Jie Xia, Guang-Heng Luo
Summary: The aim of this study was to observe the effect of the stroma proportion in hyperplasia nodules on the clinical symptoms of benign prostatic hyperplasia (BPH) patients and to identify the different genes and pathways in prostatic hyperplasia nodules between patients with epithelial-dominated hyperplasia (EDH) and stromal-dominated hyperplasia (SDH) nodules. The results showed that the symptoms of BPH patients with SDH nodules may be associated with prostate fibrosis and fibrosis may be a significant contributing factor in BPH/LUTS patients with SDH nodules.
INTERNATIONAL JOURNAL OF GENERAL MEDICINE
(2023)
Review
Urology & Nephrology
Michael Lardas, Nikos Grivas, Thomas P. A. Debray, Fabio Zattoni, Christopher Berridge, Marcus Cumberbatch, Thomas Van den Broeck, Erik Briers, Maria De Santis, Andrea Farolfi, Nicola Fossati, Giorgio Gandaglia, Silke Gillessen, Shane O'Hanlon, Ann Henry, Matthew Liew, Malcolm Mason, Lisa Moris, Daniela Oprea-Lager, Guillaume Ploussard, Olivier Rouviere, Ivo G. Schoots, Theodorus van der Kwast, Henk van der Poel, Thomas Wiegel, Peter-Paul Willemse, Cathy Y. Yuan, Jeremy P. Grummet, Derya Tilki, Roderick C. N. van den Bergh, Thomas B. Lam, Philip Cornford, Nicolas Mottet
Summary: This study systematically reviewed patient- and tumor-related prognostic factors for post-radical prostatectomy urinary incontinence (UI). The results showed that increasing age, shorter length of the membranous urethra, greater prostate volume, and higher Charlson comorbidity index were independent prognostic factors for UI within 3 months after radical prostatectomy. These factors remained predictive at 3-12 months post-surgery.
EUROPEAN UROLOGY FOCUS
(2022)
Review
Urology & Nephrology
Lisa Moris, Giorgio Gandaglia, Antoni Vilaseca, Thomas Van den Broeck, Erik Briers, Maria De Santis, Silke Gillessen, Nikos Grivas, Shane O'Hanlon, Ann Henry, Thomas B. Lam, Michael Lardas, Malcolm Mason, Daniela Oprea-Lager, Guillaume Ploussard, Olivier Rouviere, Ivo G. Schoots, Henk van der Poel, Thomas Wiegel, Peter-Paul Willemse, Cathy Y. Yuan, Jeremy P. Grummet, Derya Tilki, Roderick C. N. van den Bergh, Philip Cornford, Nicolas Mottet
Summary: Comparative studies on nerve-sparing (NS) and non-nerve-sparing (NNS) surgical techniques for prostate cancer patients showed an increased risk of positive surgical margins with NS surgery, but no negative impact on biochemical recurrence. However, methodological uncertainties exist in current research and more data is needed to support these findings.
EUROPEAN UROLOGY FOCUS
(2022)
Editorial Material
Radiology, Nuclear Medicine & Medical Imaging
Anwar R. Padhani, Masoom A. Haider, Olivier Rouviere
Summary: Before a prostate biopsy, balancing the benefits and harms of MRI results is important, as well as considering patients' preferences and tolerance. Decision curve analysis shows that combining clinical risk factors with MRI findings optimizes biopsy outcomes across a range of clinically relevant risk thresholds.
EUROPEAN RADIOLOGY
(2022)
Article
Computer Science, Artificial Intelligence
Audrey Duran, Gaspard Dussert, Olivier Rouviere, Tristan Jaouen, Pierre-Marc Jodoin, Carole Lartizien
Summary: In this study, a novel end-to-end multi-class network for the segmentation and grading of prostate cancer lesions is proposed. The model achieves high sensitivity and specificity in magnetic resonance imaging and demonstrates state-of-the-art performance in prostate segmentation.
MEDICAL IMAGE ANALYSIS
(2022)
Article
Surgery
Fabien Boucher, Michel Abihannah, Julie Chauvel-Picard, Ali A. Mojallal, Olivier Rouviere, Sophie Brosset
Summary: The reverse tensor fascia latae perforator (TFLp) flap can be a suitable option for perigenicular reconstruction in patients without the anterolateral thigh perforator (ALTp).
Review
Urology & Nephrology
Guillaume Ploussard, Olivier Rouviere, Morgan Roupret, Roderick van den Bergh, Raphaele Renard-Penna
Summary: Active surveillance is a recommended treatment option for prostate cancer management, preserving oncological and functional outcomes. Additional monitoring using relevant parameters and MRI can improve initial stratification and reduce invasive procedures. However, abandoning biopsies without MRI progression is not yet recommended in routine practice.
NATURE REVIEWS UROLOGY
(2022)
Article
Radiology, Nuclear Medicine & Medical Imaging
Au Hoang-Dinh, Trung Nguyen-Quang, Lenh Bui-Van, Christelle Gonindard-Melodelima, Remi Souchon, Olivier Rouviere
Summary: The purpose of this study was to quantify the influence of factors of variability on ADC estimation in the normal prostate peripheral zone. The results showed that the MRI scanner, the lowest b-value used, and the period of the day had a substantial impact on ADC computation.
DIAGNOSTIC AND INTERVENTIONAL IMAGING
(2022)
Article
Oncology
Ariane Lapierre, Lionel Badet, Olivier Rouviere, Gilles Crehange, Julien Berthiller, Philippe Paparel, Olivier Chapet
Summary: The purpose of this study was to determine the maximum tolerated dose for primary renal cell carcinoma treated with stereotactic body radiation therapy (SBRT). A multicentric phase 1 study was conducted using dose escalation, and it was found that there was no dose-limiting toxicity at the prescribed dose levels. The highest dose of 48 Gy in 4 fractions was deemed safe for further studies.
PRACTICAL RADIATION ONCOLOGY
(2023)
Review
Urology & Nephrology
Nikolaos Grivas, Michael Lardas, Estefania Linares Espinos, Thomas B. Lam, Olivier Rouviere, Nicolas Mottet, Roderick C. N. van den Bergh
Summary: Literature has shown that in men with an abnormal prostate magnetic resonance imaging (MRI) scan but a normal biopsy, a significant prostate cancer can be present. MRI scans should be double checked, followed by standard checkups or repeat prostate biopsy, especially in highly suspicious cases.
Editorial Material
Urology & Nephrology
Johan Stranne, Nicolas Mottet, Olivier Rouviere
Review
Radiology, Nuclear Medicine & Medical Imaging
Olivier Rouviere, Tristan Jaouen, Pierre Baseilhac, Mohammed Lamine Benomar, Raphael Escande, Sebastien Crouzet, Remi Souchon
Summary: The purpose of this study was to review the diagnostic performance of AI-based algorithms for characterizing/detecting prostate cancer on MRI. The algorithms showed promising results and performed well as standalone diagnostic tools. However, the management of discrepancies between algorithm findings and human reading needs further investigation.
DIAGNOSTIC AND INTERVENTIONAL IMAGING
(2023)
Article
Respiratory System
Vincent Cottin, Elodie Blanchard, Mallorie Kerjouan, Romain Lazor, Martine Reynaud-Gaubert, Camille Taille, Yurdagul Uzunhanj, Lidwine Wemeau, Claire Andrejak, Dany Baud, Philippe Bonniaud, Pierre-Yves Brillet, Alain Calender, Lara Chalabreysse, Isabelle Court-Fortune, Nicolas Pierre Desbaillets, Gilbert Ferretti, Anne Guillemot, Laurane Hardelin, Marianne Kambouchner, Violette Leclerc, Mathieu Lederlin, Marie-Claire Malinge, Alain Mancel, Sylvain Marchand-Adam, Jean-Michel Maury, Jean-Marc Naccache, Mouhamad Nasser, Hilario Nunes, Gaele Pagnoux, Gregoire Prevot, Christine Rousset-Jablonski, Olivier Rouviere, Salim Si-Mohamed, Renaud Touraine, Julie Traclet, Segolene Turquier, Stephane Vagnarelli, Kais Ahmad
Summary: This article presents the English-language version of the French National Diagnostic and Care Protocol for lymphangioleiomyomatosis, a rare lung disease. The protocol provides practical recommendations for diagnosing, managing, and following up with patients. The recommendations cover various aspects of the disease, including diagnosis criteria, management principles, and use of pharmaceutical specialties and treatments.
RESPIRATORY MEDICINE AND RESEARCH
(2023)
Review
Urology & Nephrology
Giancarlo Marra, Geert J. L. H. van Leenders, Fabio Zattoni, Claudia Kesch, Pawel Rajwa, Philip Cornford, Theodorus van der Kwast, Roderick C. N. van den Bergh, Erik Briers, Thomas Van den Broeck, Gert De Meerleer, Maria De Santis, Daniel Eberli, Andrea Farolfi, Silke Gillessen, Nikolaos Grivas, Jeremy P. Grummet, Ann M. Henry, Michael Lardas, Matt Lieuw, Estefania Linares Espinos, Malcolm D. Mason, Shane O'Hanlon, Inge M. van Oort, Daniela E. Oprea-Lager, Guillaume Ploussard, Olivier Rouviere, Ivo. G. Schoots, Johan Stranne, Derya Tilki, Thomas Wiegel, Peter-Paul M. Willemse, Nicolas Mottet, Giorgio Gandaglia
Summary: This study aimed to compare the oncological outcomes of conventional prostate cancer and unconventional histologic subtypes in localized disease. Unconventional histologic subtypes, such as cribriform, intraductal, and ductal prostate cancer, had worse oncological outcomes compared to conventional prostate cancer. However, mucinous and prostatic intraepithelial neoplasia (PIN)-like subtypes showed similar outcomes to conventional prostate cancer.
Article
Radiology, Nuclear Medicine & Medical Imaging
Gregoire Cazalas, Clement Klein, Gilles Piana, Eric De Kerviler, Afshin Gangi, Philippe Puech, Cosmina Nedelcu, Remi Grange, Xavier Buy, Marc-Antoine Jegonday, Pierre Bigot, Charles Karim Bensalah, Victor Gaillard, Geraldine Pignot, Philippe Paparel, Lionel Badet, Clement Michiels, Jean Christophe Bernhard, Olivier Rouviere, Nicolas Grenier, Clement Marcelin
Summary: Percutaneous-guided thermal ablation and robotic-assisted partial nephrectomy are effective treatments for T1b renal cancer; however, thermal ablation has a higher local recurrence rate.
EUROPEAN RADIOLOGY
(2023)
Article
Oncology
Stefano Fanti, Alberto Briganti, Louise Emmett, Karim Fizazi, Silke Gillessen, Karolien Goffin, Boris A. Hadaschik, Ken Herrmann, Jolanta Kunikowska, Tobias Maurer, Steven MacLennan, Nicolas Mottet, Declan G. Murphy, Daniela E. Oprea-Lager, Joe M. O'Sullivan, Wim J. G. Oyen, Olivier Rouviere, Oliver Sartor, Arnulf Stenzl, Hendrik Van Poppel, Jochen Walz, Wim Witjes, Anders Bjartell
Summary: The use and potential of PSMA PET/CT in prostate cancer treatment and management were assessed and achieved consensus among a panel of experts, particularly in utilizing PSMA PET/CT for patient selection and guiding [177Lu]Lu-PSMA therapy.
EUROPEAN UROLOGY ONCOLOGY
(2022)