Individualization of Drug Therapy: History, Present State, and Opportunities for the Future

The Genetic Basis for Cancer Treatment Decisions

(2012) Janet E. Dancey et al.   CELL

Personal Omics Profiling Reveals Dynamic Molecular and Medical Phenotypes

(2012) Rui Chen et al.   CELL

Physiologically-Based Pharmacokinetics in Drug Development and Regulatory Science

(2011) Malcolm Rowland et al.   Annual Review of Pharmacology and Toxicology

Dosing Clopidogrel Based on CYP2C19 Genotype and the Effect on Platelet Reactivity in Patients With Stable Cardiovascular Disease

(2011) Jessica L. Mega et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Therapeutic Drug Monitoring of Voriconazole and Posaconazole

(2011) Trana Hussaini et al.   PHARMACOTHERAPY

Diseases in a Dish

(2011) Stephen S. Hall   SCIENTIFIC AMERICAN

A Semi-Mechanistic Model to Predict the Effects of Liver Cirrhosis on Drug Clearance

(2010) Trevor N. Johnson et al.   CLINICAL PHARMACOKINETICS

Enrichment of Clinical Study Populations

(2010) R Temple   CLINICAL PHARMACOLOGY & THERAPEUTICS

Applications of Physiologically Based Pharmacokinetic (PBPK) Modeling and Simulation During Regulatory Review

(2010) P Zhao et al.   CLINICAL PHARMACOLOGY & THERAPEUTICS

What Is Clinical Utility and Why Should We Care?

(2010) L J Lesko et al.   CLINICAL PHARMACOLOGY & THERAPEUTICS

Therapeutic drug monitoring of lopinavir/ritonavir in pregnancy

(2010) JS Lambert et al.   HIV MEDICINE

Warfarin Genotyping Reduces Hospitalization Rates

(2010) Robert S. Epstein et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

DNA, drugs and chariots: on a decade of pharmacogenomics at the US FDA

(2010) Lawrence J Lesko et al.   PHARMACOGENOMICS

Association of Cytochrome P450 2C19 Genotype With the Antiplatelet Effect and Clinical Efficacy of Clopidogrel Therapy

(2009) Alan R. Shuldiner   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Quantitative Evaluation of Pharmacokinetic Inhibition of CYP3A Substrates by Ketoconazole: A Simulation Study

(2009) Ping Zhao et al.   JOURNAL OF CLINICAL PHARMACOLOGY

Genomic and personalized medicine: foundations and applications

(2009) Geoffrey S. Ginsburg et al.   Translational Research

Physiology-Based Simulations of a Pathological Condition

(2008) Andrea N Edginton et al.   CLINICAL PHARMACOKINETICS

Systems biology: Metabonomics

(2008) Jeremy K. Nicholson et al.   NATURE

HLA-B*5701 Screening for Hypersensitivity to Abacavir

(2008) Simon Mallal et al.   NEW ENGLAND JOURNAL OF MEDICINE