Cardiovascular Pharmacogenomics of Adrenergic Receptor Signaling: Clinical Implications and Future Directions

HK-2 Human Renal Proximal Tubule Cells as a Model for G Protein–Coupled Receptor Kinase Type 4–Mediated Dopamine 1 Receptor Uncoupling

(2010) John J. Gildea et al.   HYPERTENSION

Common genetic variation of β1- and β2-adrenergic receptor and response to four classes of antihypertensive treatment

(2010) Timo Suonsyrjä et al.   Pharmacogenetics and Genomics

Haplotypes of the adrenergic system predict the blood pressure response to β-blockers in women with essential hypertension

(2010) Fabiana Filigheddu et al.   PHARMACOGENOMICS

Common ADRB2 Haplotypes Derived from 26 Polymorphic Sites Direct β2-Adrenergic Receptor Expression and Regulation Phenotypes

(2010) Alfredo Panebra et al.   PLoS One

2009 Focused Update: ACCF/AHA Guidelines for the Diagnosis and Management of Heart Failure in Adults

(2009) et al.   CIRCULATION

An α 2C -Adrenergic Receptor Polymorphism Alters the Norepinephrine-Lowering Effects and Therapeutic Response of the β-Blocker Bucindolol in Chronic Heart Failure

(2009) Michael R. Bristow et al.   Circulation-Heart Failure

Clinical and Genetic Modifiers of Long-Term Survival in Heart Failure

(2009) Sharon Cresci et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

Impact of β1-Adrenergic Receptor Polymorphisms on Susceptibility to Heart Failure, Arrhythmogenesis, Prognosis, and Response to Beta-Blocker Therapy

(2008) Andréia Biolo et al.   AMERICAN JOURNAL OF CARDIOLOGY

 1- and  2-Adrenergic Receptor Gene Variation,  -Blocker Use and Risk of Myocardial Infarction and Stroke

(2008) R. N. Lemaitre et al.   AMERICAN JOURNAL OF HYPERTENSION

Multiple interactions between the alpha2C- and beta1-adrenergic receptors influence heart failure survival

(2008) Sharon LR Kardia et al.   BMC Medical Genetics

β-Adrenergic Receptor Gene Polymorphisms and β-Blocker Treatment Outcomes in Hypertension

(2008) MA Pacanowski et al.   CLINICAL PHARMACOLOGY & THERAPEUTICS

Lack of Association Between Adrenergic Receptor Genotypes and Survival in Heart Failure Patients Treated With Carvedilol or Metoprolol

(2008) Amy J. Sehnert et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

A GRK5 polymorphism that inhibits β-adrenergic receptor signaling is protective in heart failure

(2008) Stephen B Liggett et al.   NATURE MEDICINE