The Roles of Neurotrophic Factor and Wnt Signaling in Depression

A Novel Role of the WNT-Dishevelled-GSK3  Signaling Cascade in the Mouse Nucleus Accumbens in a Social Defeat Model of Depression

(2011) M. B. Wilkinson et al.   JOURNAL OF NEUROSCIENCE

Inhibition of glycogen synthase kinase-3 is necessary for the rapid antidepressant effect of ketamine in mice

(2011) E Beurel et al.   MOLECULAR PSYCHIATRY

Signaling pathways underlying the rapid antidepressant actions of ketamine

(2011) Ronald S. Duman et al.   NEUROPHARMACOLOGY

Induction of the Wnt Antagonist Dickkopf-1 Is Involved in Stress-Induced Hippocampal Damage

(2011) Francesco Matrisciano et al.   PLoS One

Wnt7a signaling promotes dendritic spine growth and synaptic strength through Ca2+/Calmodulin-dependent protein kinase II

(2011) L. Ciani et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Stress, sex, and neural adaptation to a changing environment: mechanisms of neuronal remodeling

(2010) Bruce S. McEwen   Annals of the New York Academy of Sciences

Modulation in Activation and Expression of Phosphatase and Tensin Homolog on Chromosome Ten, Akt1, and 3-Phosphoinositide-Dependent Kinase 1: Further Evidence Demonstrating Altered Phosphoinositide 3-Kinase Signaling in Postmortem Brain of Suicide Subjects

(2010) Yogesh Dwivedi et al.   BIOLOGICAL PSYCHIATRY

Wnt2 Expression and Signaling Is Increased by Different Classes of Antidepressant Treatments

(2010) Hideki Okamoto et al.   BIOLOGICAL PSYCHIATRY

Frizzled-5, a receptor for the synaptic organizer Wnt7a, regulates activity-mediated synaptogenesis

(2010) M. Sahores et al.   DEVELOPMENT

Canonical Wnt3a Modulates Intracellular Calcium and Enhances Excitatory Neurotransmission in Hippocampal Neurons

(2010) Miguel E. Avila et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

A negative regulator of MAP kinase causes depressive behavior

(2010) Vanja Duric et al.   NATURE MEDICINE

Long-term depression in the CNS

(2010) Graham L. Collingridge et al.   NATURE REVIEWS NEUROSCIENCE

Is Glycogen Synthase Kinase-3 a Central Modulator in Mood Regulation?

(2010) Xiaohua Li et al.   NEUROPSYCHOPHARMACOLOGY

mTOR-Dependent Synapse Formation Underlies the Rapid Antidepressant Effects of NMDA Antagonists

(2010) N. Li et al.   SCIENCE

Blocked Inhibitory Serine-Phosphorylation of Glycogen Synthase Kinase-3α/β Impairs In Vivo Neural Precursor Cell Proliferation

(2009) Tae-Yeon Eom et al.   BIOLOGICAL PSYCHIATRY

Stress-Induced Dendritic Remodeling in the Prefrontal Cortex is Circuit Specific

(2009) R. M. Shansky et al.   CEREBRAL CORTEX

Wnt2 Regulates Progenitor Proliferation in the Developing Ventral Midbrain

(2009) Kyle M. Sousa et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Dentate gyrus-specific knockdown of adult neurogenesis impairs spatial and object recognition memory in adult rats

(2009) S. Jessberger et al.   LEARNING & MEMORY

Interactions between BDNF Val66Met polymorphism and early life stress predict brain and arousal pathways to syndromal depression and anxiety

(2009) J M Gatt et al.   MOLECULAR PSYCHIATRY

Wnts blow on NeuroD1 to promote adult neuron production and diversity

(2009) Pierre Vanderhaeghen   NATURE NEUROSCIENCE

Emerging roles of Wnts in the adult nervous system

(2009) Nibaldo C. Inestrosa et al.   NATURE REVIEWS NEUROSCIENCE

Role of the Wnt receptor Frizzled-1 in presynaptic differentiation and function

(2009) Lorena Varela-Nallar et al.   Neural Development

Wnt Signaling Mediates Experience-Related Regulation of Synapse Numbers and Mossy Fiber Connectivities in the Adult Hippocampus

(2009) Nadine Gogolla et al.   NEURON

Ketamine and the next generation of antidepressants with a rapid onset of action

(2009) Rodrigo Machado-Vieira et al.   PHARMACOLOGY & THERAPEUTICS

Brain structural and functional abnormalities in mood disorders: implications for neurocircuitry models of depression

(2008) Wayne C. Drevets et al.   Brain Structure & Function

The molecular neurobiology of depression

(2008) Vaishnav Krishnan et al.   NATURE

Targeting the glutamatergic system to develop novel, improved therapeutics for mood disorders

(2008) Gerard Sanacora et al.   NATURE REVIEWS DRUG DISCOVERY