Functional Characterization of Liver Enhancers That Regulate Drug-Associated Transporters

Membrane transporters in drug development

(2010)   NATURE REVIEWS DRUG DISCOVERY

Impact of OATP transporters on pharmacokinetics

(2009) A Kalliokoski et al.   BRITISH JOURNAL OF PHARMACOLOGY

Regulatory polymorphisms in key candidate genes for disease susceptibility and drug response: a mandate for valid genetic biomarkers

(2009) Wolfgang Sadee   EXPERT REVIEW OF MOLECULAR DIAGNOSTICS

Allelic imbalance (AI) identifies novel tissue-specificcis-regulatory variation for humanUGT2B15

(2009) Chang Sun et al.   HUMAN MUTATION

Germline Genetic Variation in an Organic Anion Transporter Polypeptide Associated With Methotrexate Pharmacokinetics and Clinical Effects

(2009) Lisa R. Treviño et al.   JOURNAL OF CLINICAL ONCOLOGY

Functional Genetic Variation in the Basal Promoter of the Organic Cation/Carnitine Transporters OCTN1 (SLC22A4) and OCTN2 (SLC22A5)

(2009) H. Tahara et al.   JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS

Modeling tissue-specific structural patterns in human and mouse promoters

(2009) Alexis Vandenbon et al.   NUCLEIC ACIDS RESEARCH

Identification and characterization of novel polymorphisms in the basal promoter of the human transporter, MATE1

(2009) Ji Ha Choi et al.   Pharmacogenetics and Genomics

Genetic variants in multidrug and toxic compound extrusion-1, hMATE1, alter transport function

(2009) Ying Chen et al.   PHARMACOGENOMICS JOURNAL

Genetic Variation in the Proximal Promoter of ABC and SLC Superfamilies: Liver and Kidney Specific Expression and Promoter Activity Predict Variation

(2009) Stephanie E. Hesselson et al.   PLoS One

Pharmacogenomics: Inter-ethnic and Intra-ethnic Differences in Pharmacokinetic and Pharmacodynamic Profiles of Clinically Relevant Drugs

(2009) Ichiro IEIRI et al.   YAKUGAKU ZASSHI-JOURNAL OF THE PHARMACEUTICAL SOCIETY OF JAPAN

Effect of pregnane X receptor ligands on transport mediated by human OATP1B1 and OATP1B3

(2008) Chunshan Gui et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Identification and Characterization of Proximal Promoter Polymorphisms in the Human Concentrative Nucleoside Transporter 2 (SLC28A2)

(2008) S. W. Yee et al.   JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS

Organic Anion Transporter 2 (SLC22A7) Is a Facilitative Transporter of cGMP

(2008) C. D. Cropp et al.   MOLECULAR PHARMACOLOGY

Xenobiotic transporters of the human organic anion transporting polypeptides (OATP) family

(2008) B. Hagenbuch et al.   XENOBIOTICA