Safety Assessment and Dose Selection for First-in-Human Clinical Trials With Immunomodulatory Monoclonal Antibodies

CD28 Superagonists: What Makes the Difference in Humans?

(2008) Burkhart Schraven et al.   IMMUNITY

Toward experimental assessment of receptor occupancy: TGN1412 revisited

(2008) Zoe Waibler et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

CTLA-4: Negative Regulator of the Immune Response and a Target for Cancer Therapy

(2008) Ulrich Keilholz   JOURNAL OF IMMUNOTHERAPY

Signaling Signatures and Functional Properties of Anti-Human CD28 Superagonistic Antibodies

(2008) Zoe Waibler et al.   PLoS One

The effects of antibody treatment on regulatory CD4+CD25+ T cells

(2008) Huanfa Yi et al.   TRANSPLANT IMMUNOLOGY

Studies of monkey complement: measurement of cynomolgus monkey CH50, ACH50, C4, C2 and C3

(2008) Hengjie Xu et al.   XENOTRANSPLANTATION

Scientific review and recommendations on preclinical cardiovascular safety evaluation of biologics

(2008) Hugo M. Vargas et al.   JOURNAL OF PHARMACOLOGICAL AND TOXICOLOGICAL METHODS