期刊
CLINICAL PEDIATRICS
卷 49, 期 3, 页码 258-270出版社
SAGE PUBLICATIONS INC
DOI: 10.1177/0009922809335668
关键词
NIDCAP; prematurity; neuropsychological function; EEG; spectral coherence
类别
资金
- U.S. Department of Education (NIHR, NIDRR, and NCRI-ECI) [HO24S90003, HO23C970032, HI33G20203, R305T990294]
- National Institutes of Health [RO1HD3826]
- I. B. Harris Foundation
- National Institute of Healt [P30HD18655]
The current study reports the effects of NIDCAP (Newborn Individualized Developmental Care and Assessment Program) at 8 years of age for a randomized controlled trial of 38 very early born (<= 29 weeks postmenstrual age), high-risk preterm infants. It was hypothesized that the experimental group at school age in comparison with the control group would perform significantly better neuropsychologically and neuroelectrophysiologically. Twenty-two (11 control, 11 experimental) children of the original 38 (18 control, 20 experimental) participants were studied at school age with a detailed neuropsychological battery and with EEG spectral coherence measures. Results indicated significantly better right hemisphere and frontal lobe function in the experimental group than the control group, both neuropsychologically and neurophysiologically. Neurobehavioral and physiological results in the newborn period successfully predicted the beneficial brain function effects at age 8 years. Results support the conclusion that the NIDCAP intervention has lasting effects into school age.
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