Article
Oncology
Jean-Baptiste Melan, Pierre Philouze, Pierre Pradat, Nazim Benzerdjeb, Jacques Blanc, Philippe Ceruse, Carine Fuchsmann
Summary: This study aimed to assess the impact of surgical resection and free flap reconstruction of soft palate cancer on speech, swallowing, and quality of life. The results showed satisfactory speech and swallowing outcomes post-surgery, with relatively little impact on patient quality of life.
Article
Audiology & Speech-Language Pathology
Kelly Greyce Sukar Cavalcanti de Oliveira, Zulina Souza de Lira, Hilton Justino da Silva, Jonia Alves Lucena, Adriana de Oliveira Camargo Gomes
Summary: The purpose of this study was to investigate the immediate effects of a flexible resonance tube and lip trill on oropharyngeal geometry and vocal acoustic parameters in singers without vocal symptoms. The results showed that the FRT exercise increased vocal tract length, while the LTT technique improved the glottal to noise excitation ratio. Additionally, men had larger oral cavity volume compared to women, and the application of these techniques resulted in increased vocal tract volume.
Article
Health Care Sciences & Services
Nisreen Naser Al Awaji, Khaled Abdulraheem Alghamdi, Abdullah Mohammed Alfaris, Rahaf Zamil Alzamil, Lojain Naser Alhijji, Ghaida Saad Alyehya, Shadan Mohammed Al Harbi, Eman M. Mortada
Summary: This study investigated the prevalence of perceived voice disorders among female university teaching faculty and identified stress, reflux, and asthma as significant factors related to self-perceived voice disorders. Furthermore, the study data showed that self-perceived voice disorders negatively impacted the overall quality of life of teaching faculty.
JOURNAL OF PERSONALIZED MEDICINE
(2023)
Article
Chemistry, Multidisciplinary
Ander Gonzalez-Docasal, Aitor Alvarez
Summary: Voice cloning, an emerging field, aims to generate synthetic utterances resembling specific individuals. This study investigates techniques for improving voice cloning quality, focusing on a low-quality dataset and comparing with high-quality corpora. Evaluations select suitable data for training a voice-cloning system and ablations remove lower quality and more variable audio files to decrease heterogeneity. An algorithm utilizing the Tacotron 2 attention matrix calculates alignment quality, and experiments show significant quality improvement in synthesised audio for the challenging low-quality corpus. Results suggest comparable audio quality between models trained on a 3 h pre-trained corpus and those trained from scratch using larger amounts of data.
APPLIED SCIENCES-BASEL
(2023)
Article
Oncology
Chung-Kan Tsao, Filippo Marchi, Chung-Jan Kang, Claudio Sampieri, Yi-An Lu, Shiang-Fu Huang, Yu-Ting Chen, Giorgio Giordano, Giorgio Peretti, Giampiero Parrinello, Andrea Iandelli, Tuan-Jen Fang
Summary: Laryngopharyngectomy is the preferred treatment for locally advanced pharyngolaryngeal tumors. Loss of speech capacity significantly affects patient-reported quality of life. A novel surgical technique, called J-flap, offers a potential alternative for voice restoration without the need for a voice prosthesis. This study aimed to compare the subjective and objective vocal outcomes and their impact on overall and voice-related quality of life between tracheoesophageal puncture with a voice prosthesis and J-flap reconstruction.
Review
Oncology
Noorazrul Yahya, Hanani Abdul Manan
Summary: Synthesizing evidence from multiple studies, we found that proton therapy has advantages over photon therapy in terms of quality of life and patient-reported outcomes for oropharyngeal cancers. However, further confirmation is needed through randomized controlled trials due to potential biases in the existing studies.
Article
Oncology
Susanne I. Scott, Anne Kathrine O. Madsen, Niclas Rubek, Birgitte W. Charabi, Irene Wessel, Sara Fredslund Hadju, Claus V. Jensen, Sarah Stephen, Joanne M. Patterson, Jeppe Friborg, Kathrine A. Hutcheson, Henrik Kehlet, Christian von Buchwald
Summary: A longitudinal comparison of functional and quality of life outcomes in patients treated for OPSCC revealed persistent impairment in swallowing function in both groups, with only the TORS group showing worse scores in one QoL subscale (sticky saliva) at 12-month follow-up.
Article
Oncology
Nedeljko Jovanovic, Colleen Dreyer, Sarah Hawkins, Kendra Thouless, David Palma, Philip C. Doyle, Julie A. Theurer
Summary: Patients treated for oropharyngeal cancer are at increased risk for functional decline, with weight and swallowing-related quality of life decreasing significantly in the first year post-treatment regardless of feeding tube placement. These findings can improve patient monitoring and communication in the clinical setting, potentially leading to better outcomes for those with OPC.
SUPPORTIVE CARE IN CANCER
(2021)
Article
Medicine, General & Internal
Chen-Chi Wang, Jia-Shiou Liao
Summary: This study investigated the correlation between scores on the VHI, its shortened version (VHI-10), and the V-RQOL for Mandarin-speaking laryngectomees using PAL and ES. The results showed that the scores on the Mandarin long-form VHI and the VHI-10 were highly correlated with each other, while they were moderately correlated with the V-RQOL scores. The Mandarin versions of long-form VHI, short-form VHI, and MA-VHI-10 were found to be interchangeable for a Mandarin-speaking alaryngeal population.
JOURNAL OF THE CHINESE MEDICAL ASSOCIATION
(2022)
Review
Computer Science, Artificial Intelligence
Awais Khan, Khalid Mahmood Malik, James Ryan, Mikul Saravanan
Summary: This work conducts a review of spoofing detection methods using hand-crafted features, deep learning, and end-to-end solutions. It evaluates the effectiveness of these methods against logical access attacks and physical access attacks, and reviews integrated solutions to voice spoofing evaluation and speaker verification, as well as adversarial and anti-forensic attacks. The study presents experimental analysis, performance evaluations, and cross-corpus assessments to assess the generalizability of existing solutions.
ARTIFICIAL INTELLIGENCE REVIEW
(2023)
Article
Medicine, General & Internal
Irini Youssef, Jennifer Yoon, Nader Mohamed, Kaveh Zakeri, Robert H. Press, Linda Chen, Daphna Y. Gelblum, Sean M. McBride, Chiaojung Jillian Tsai, Nadeem Riaz, Yao Yu, Marc A. Cohen, Lara Ann Dunn, Alan L. Ho, Richard J. Wong, Loren S. Michel, Jay O. Boyle, Bhuvanesh Singh, Anuja Kriplani, Ian Ganly, Eric J. Sherman, David G. Pfister, James Fetten, Nancy Y. Lee
Summary: This study compared the toxic effects and oncologic outcomes of patients with newly diagnosed nonmetastatic oropharyngeal carcinoma (OPC) treated with intensity-modulated proton therapy (IMPT) or intensity-modulated radiation therapy (IMRT). The results showed that IMPT treatment was associated with reduced acute toxicity and favorable oncologic outcomes compared to IMRT.
Article
Audiology & Speech-Language Pathology
Kimberly L. Dahl, Hasini R. Weerathunge, Daniel P. Buckley, Anton S. Dolling, Manuel Diaz-Cadiz, Lauren F. Tracy, Cara E. Stepp
Summary: This study evaluated the reliability and accuracy of auditory-perceptual voice evaluations by experienced clinicians through telepractice platforms, finding that transmission conditions and dysphonia percepts have significant effects on average ratings and interrater agreement. However, overall severity had the highest agreement while strain had the lowest. Telepractice transmission does not substantially reduce the reliability or accuracy of such evaluations.
AMERICAN JOURNAL OF SPEECH-LANGUAGE PATHOLOGY
(2021)
Article
Medicine, Legal
Ricky K. W. Chan
Summary: This study investigates the acoustics of laryngeal voice quality and its impact on forensic voice comparison. The results indicate that voice quality parameters have promising results when speech style is controlled for, but their discriminative value is limited in cases involving speech style mismatch.
FORENSIC SCIENCE INTERNATIONAL
(2023)
Article
Otorhinolaryngology
Puja Aggarwal, Katherine A. Hutcheson, Adam S. Garden, Frank E. Mott, Ryan P. Goepfert, Amber Duvall, Clifton D. Fuller, Stephen Y. Lai, G. Brandon Gunn, Erich M. Sturgis, Ehab Y. Hanna, Sanjay Shete
Summary: The study identified Black race, Hispanic ethnicity, current cigarette smoking, specific chemotherapy and radiation doses as factors associated with the severity of voice and speech symptoms in oropharyngeal cancer survivors.
JAMA OTOLARYNGOLOGY-HEAD & NECK SURGERY
(2021)
Article
Otorhinolaryngology
Esther Lee, Hannah R. Crowder, Daniel Gorelik, Christopher Badger, Jennifer Schottler, Ning-Wei Li, Robert Siegel, Nader Sadeghi, Punam G. Thakkar, Arjun S. Joshi, Joseph F. Goodman
Summary: NAC + S treatment offers favorable long-term quality of life, as indicated by near-normal scores in most quality of life domains.
EUROPEAN ARCHIVES OF OTO-RHINO-LARYNGOLOGY
(2022)
Article
Dentistry, Oral Surgery & Medicine
P. James, F. Bekiroglu, D. Broderick, O. Khattak, D. Lowe, A. Schache, R. J. Shaw, S. N. Rogers
Summary: The COVID-19 pandemic prompted a shift in postoperative care for microvascular free tissue transfer patients from the high dependency unit (HDU) to the ward. This retrospective study compared outcomes before and during the pandemic, and found that ward-based care was safe and helped alleviate bed pressures in the HDU. Case selection should be done carefully.
BRITISH JOURNAL OF ORAL & MAXILLOFACIAL SURGERY
(2022)
Article
Otorhinolaryngology
Simon N. Rogers, Ashni Adatia, Stephanie Hackett, Angela Boscarino, Anika Patel, Derek Lowe, Christopher J. Butterworth
Summary: This study reports on the changes in reconstruction and oral rehabilitation of maxillary defects since 1994. A total of 186 patients were included, with the majority of tumors located in the alveolus and hard palate. Significant changes were observed over time in reconstruction type, use of implants, dental restoration, and length of hospital stay.
EUROPEAN ARCHIVES OF OTO-RHINO-LARYNGOLOGY
(2022)
Article
Dentistry, Oral Surgery & Medicine
J. Twigg, A. Kanatas, G. M. Humphris, D. Lowe, S. N. Rogers
Summary: The aim of this study was to evaluate the usability of a single-page condition-specific prompt list, the Patient Concerns Inventory (PCIHN), in assessing health-related quality of life (HRQOL). The results showed that certain items and the total number of items in the PCI-HN could predict poor HRQOL.
INTERNATIONAL JOURNAL OF ORAL AND MAXILLOFACIAL SURGERY
(2022)
Article
Oncology
Anastasios Kanatas, Derek Lowe, Simon N. Rogers
Summary: During clinical follow-up, using HRQOL questionnaires and prompt lists can help identify the needs of head and neck cancer patients and provide additional support. Baseline HRQOL is a significant predictor of HRQOL 12 months later, and patients with lower baseline HRQOL may benefit more from using prompt lists.
Article
Economics
Victory 'Segun Ezeofor, Llinos Haf Spencer, Simon N. Rogers, Anastasios Kanatas, Derek Lowe, Cherith J. Semple, Jeffrey R. Hanna, Seow Tien Yeo, Rhiannon Tudor Edwards
Summary: The study conducted an economic evaluation of the PCI in head and neck cancer patients, finding that the PCI intervention was cost-effective and cost-saving, with a higher quality-adjusted life-year (QALY) gain compared to the non-PCI group. Consultants using the PCI reported a better awareness of patients' post-treatment needs, showing that the PCI is a low-cost intervention that provides benefits to patients and is supported in routine practice.
PHARMACOECONOMICS-OPEN
(2022)
Article
Dentistry, Oral Surgery & Medicine
S. N. Rogers, D. Lowe, A. W. Midgley
Summary: This study examined the interest and reasons for participation in an exercise program among head and neck cancer patients. The findings suggest that personalized interventions tailored to the specific needs of the patients, supported by patient peers, can help motivate participation in exercise.
INTERNATIONAL JOURNAL OF ORAL AND MAXILLOFACIAL SURGERY
(2022)
Review
Otorhinolaryngology
Anastasios Kanatas, Derek Lowe, Simon N. Rogers
Summary: This article reviews the development, validation, and clinical implications of the Patient Concerns Inventory for head and neck cancer (PCI-HN). It provides an overview of the PCI-HN's background, evaluation, and utility, which is essential for multidisciplinary teams and researchers.
EUROPEAN ARCHIVES OF OTO-RHINO-LARYNGOLOGY
(2022)
Article
Physiology
Adrian W. Midgley, Andrew R. Levy, Felipe A. Cunha, Angela Key, Joanne M. Patterson, Simon N. Rogers
Summary: The purpose of this study was to assess the safety and feasibility of using the cardiopulmonary exercise test (CPET) for evaluating head and neck cancer (HaNC) survivors. The study also aimed to compare their cardiorespiratory fitness to age and sex-matched norms and establish their current physical activity levels. The results showed that most HaNC survivors had lower levels of cardiorespiratory fitness, which should be taken into account when determining an appropriate ramp rate.
CLINICAL PHYSIOLOGY AND FUNCTIONAL IMAGING
(2023)
Article
Oncology
Cecilie Hollaender-Mieritz, Anne Marie Juhl Elsborg, Claus Andrup Kristensen, Simon N. Rogers, Helle Pappot, Karin Piil
Summary: This study aims to establish a patient concerns inventory (PCI-HNC-PT) for patients with advanced head and neck cancer receiving palliative treatment. Through patient interviews and a focus group interview with oncology nurses, the items and concerns for the PCI-HNC-PT were determined.
SUPPORTIVE CARE IN CANCER
(2023)
Article
Otorhinolaryngology
Hisham Mehanna, Ben Carter, Andrew K. Hartley, Ahmad K. Abou-Foul, Jill Brooks, June Jones, Lydia Fresco, Laura M. Moss, Terence M. N. Jones, Simon N. P. Rogers, Randall P. Morton, ETERMIN Study Management Grp
Summary: The study aims to determine patients' preferences and willingness to complete commonly used head-and-neck cancer quality of life questionnaires in routine follow-up clinics. Results showed that 82% of respondents found the questionnaires useful for communicating their health concerns, with patients preferring structured disease-specific instruments and disliking unstructured patient-generated lists. However, only 55% of patients expressed support for completing questionnaires routinely at the clinic.
CLINICAL OTOLARYNGOLOGY
(2023)
Article
Audiology & Speech-Language Pathology
Ann Edwards, Alison Holm, Paul Carding, Michael Steele, Elspeth Froude, Clare Burns, Elizabeth Cardell
Summary: This research compares the effectiveness of independent online and blended learning approaches for developing VFSS analytical skills among novice analysts. The study finds that all three training approaches improve novice analysts' ability to identify impairments on VFSS. However, expert facilitation leads to better decision-making skills, higher confidence, and greater engagement in learning.
INTERNATIONAL JOURNAL OF SPEECH-LANGUAGE PATHOLOGY
(2023)
Article
Multidisciplinary Sciences
Adrian W. Midgley, Andrew R. Levy, Simon N. Rogers, Rachel C. Brooker, Valerie Bryant, Mary Gemma Cherry, Steven Lane, Michael M. Nugent, Ruth Price, Andrew G. Schache, Bridget Young, Joanne M. Patterson
Summary: The aim of this study is to investigate the feasibility and acceptability of introducing a remotely delivered, fully personalised, collaborative, and flexible exercise programme into the usual care pathway for head and neck cancer patients. The study will recruit 70 patients and assess the retention, uptake, and adherence to the exercise programme, as well as the impact on fatigue, quality of life, physical activity levels, and physical fitness. The results of this feasibility study will inform the design of a future randomised controlled trial.
Review
Oncology
Hannah C. Doughty, Ruaraidh A. Hill, Andrew Riley, Adrian W. Midgley, Joanne M. Patterson, Lynne M. Boddy, Simon N. Rogers, Michelle Maden, Nefyn H. Williams
Summary: This review explored barriers to and facilitators of physical activity promotion and participation in cancer patients. Educating patients and healthcare professionals on the benefits and safety of physical activity may facilitate promotion, uptake, and adherence. Head and neck cancer patients experienced barriers not cited across other cancers, and research exploring physical activity promotion in this patient group is required to improve physical activity engagement.
SUPPORTIVE CARE IN CANCER
(2023)
Article
Oncology
Corrie Dicks, Simon N. Rogers, Anastasios Kanatas, Derek Lowe, Calum Mchale, Gerry Humphris
Summary: This study investigated the number of concerns raised by patients using the Patient Concerns Inventory (PCI) and those who did not raise concerns. The study also examined who initiated the concerns and the factors that may predict this initiation.
SUPPORTIVE CARE IN CANCER
(2023)
Article
Surgery
A. Kanatas, D. Coffey, J. Spellman, J. Twigg, D. Lowe, S. N. Rogers
Summary: This study reports on the follow-up pattern of head and neck cancer patients in two large UK centers during the COVID-19 pandemic. The findings suggest that remote consultations were favored by clinicians, but variations in practice were observed, leading to a "hybrid follow-up approach". The study recommends developing a personalized follow-up model based on risk stratification, and further evaluating the mode of such consultations.
ANNALS OF THE ROYAL COLLEGE OF SURGEONS OF ENGLAND
(2023)