Review
Nutrition & Dietetics
Nicola Veronese, Ligia J. Dominguez, Damiano Pizzol, Jacopo Demurtas, Lee Smith, Mario Barbagallo
Summary: Oral magnesium supplementation has been shown to improve glucose metabolism in people with diabetes, leading to a reduction in fasting plasma glucose levels. It also has positive effects on glucose parameters and insulin sensitivity markers in individuals at high risk of diabetes. This suggests that magnesium supplementation may be beneficial in managing diabetes and improving insulin sensitivity.
Article
Endocrinology & Metabolism
Hongdian Li, Mingxuan Li, Shaoning Dong, Sai Zhang, Ao Dong, Mianzhi Zhang
Summary: This study used Mendelian randomization to investigate the direct effect of thyroid characteristics on diabetic kidney disease (DKD) and diabetic retinopathy (DR). The results showed that abnormal thyroid hormone levels were associated with the occurrence of DKD and decreased glomerular filtration rate, but not with DR.
FRONTIERS IN ENDOCRINOLOGY
(2023)
Article
Multidisciplinary Sciences
Lynette J. Oost, Julia I. P. van Heck, Cees J. Tack, Jeroen H. F. de Baaij
Summary: This study investigated the prevalence of hypomagnesemia and its correlation with metabolic determinants in adults with type 1 diabetes. The results suggest that hypomagnesemia in individuals with type 1 diabetes is associated with insulin resistance.
SCIENTIFIC REPORTS
(2022)
Review
Nutrition & Dietetics
Maria del Carmen Macias Ruiz, Lorena Cuenca Bermejo, Nicola Veronese, Emiliano Fernandez Villalba, Ana Maria Gonzalez Cuello, Karolina Kublickiene, Valeria Raparelli, Colleen M. Norris, Alexandra Kautzky-Willer, Louise Pilote, Mario Barbagallo, Ligia Dominguez, Maria Trinidad Herrero
Summary: This article reviews the role of magnesium in health and illness, with emphasis on the elderly population with chronic kidney disease (CKD) and potential sex differences. It is found that magnesium can be used as an adjunctive treatment for CKD patients to improve glomerular filtration, but further research and characterization are needed for its clinical applications. Therefore, well-designed prospective clinical trials are needed to establish guidelines for magnesium supplementation, considering age and sex.
Article
Multidisciplinary Sciences
Varun Kavuru, Ryan S. Senger, John L. Robertson, Devasmita Choudhury
Summary: Chronic kidney disease (CKD) is a major public health burden, with diabetes mellitus (DM) being one of the main causes. Raman spectroscopy and chemometric modeling of urine samples can potentially differentiate diabetic kidney disease (DKD) from other glomerular damage causes.
Article
Medicine, General & Internal
Jin-Woo Park, Eun-Kyoung Kim, Jiyoun Lee, Seung Hyun Chung, Gihong Boo, Sang-Hwan Do
Summary: This study investigated the effects of intraoperative magnesium administration on postoperative glucose control in patients with diabetes. The results showed that patients treated with magnesium had lower mean glucose levels, lower incidence of high blood glucose levels, and lower insulin requirements compared to the control group. This suggests that magnesium infusion is beneficial for improving postoperative blood glucose profiles in patients with diabetes.
JOURNAL OF CLINICAL MEDICINE
(2022)
Review
Medicine, General & Internal
Mohamed Hassanein, Tariq Shafi
Summary: This review article focuses on the role of the kidneys in glucose metabolism and discusses the benefits, limitations, and evidence behind glycemic markers in patients with chronic kidney disease. The article specifically highlights the emerging minimally invasive technique of continuous glucose monitoring for glycemic assessment.
Article
Endocrinology & Metabolism
Feifei Cheng, Andrea O. Luk, Hongjiang Wu, Claudia H. T. Tam, Cadmon K. P. Lim, Baoqi Fan, Guozhi Jiang, Luke Carroll, Aimin Yang, Eric S. H. Lau, Alex C. W. Ng, Heung Man Lee, Elaine Chow, Alice P. S. Kong, Anthony C. Keech, Mugdha Joglekar, Wing Yee So, Anandwardhan A. Hardikar, Juliana C. N. Chan, Alicia J. Jenkins, Ronald C. W. Ma
Summary: This study found that rLTL is independently associated with incident ESKD and rapid eGFR decline in Chinese individuals with type 2 diabetes. Shorter rLTL at baseline was linked to a higher risk of developing ESKD and a faster decline in kidney function during follow-up. Telomere length may serve as a useful biomarker for predicting kidney disease progression in type 2 diabetes patients.
Article
Multidisciplinary Sciences
Pietro Hiram Guzzi, Francesca Cortese, Gaia Chiara Mannino, Elisabetta Pedace, Elena Succurro, Francesco Andreozzi, Pierangelo Veltri
Summary: This study presents a framework for analyzing the relationship between type 2 diabetes and comorbidities, considering age variations. By integrating existing data sources and novel algorithms, the study identifies genes that significantly change their expression in specific tissues over time and reconstructs the associated protein interaction networks and pathways. The findings reveal interesting pathways related to type 2 diabetes, insulin regulation, and brain activities, providing insights for the development of specific therapies.
SCIENTIFIC REPORTS
(2023)
Review
Endocrinology & Metabolism
Yu Ren, Shuang Sun, Yongwei Su, Chenfei Ying, Hua Luo
Summary: This study analyzed the effect of fruit consumption on glucose control and found that increasing fruit intake can reduce fasting blood glucose concentration, but has no significant effect on glycosylated hemoglobin. It is recommended for patients with diabetes to increase fruit intake while ensuring that total energy intake remains unchanged.
FRONTIERS IN ENDOCRINOLOGY
(2023)
Review
Endocrinology & Metabolism
James Ling, Jack K. C. Ng, Juliana C. N. Chan, Elaine Chow
Summary: Diabetes is the leading cause of chronic kidney disease (CKD) in developed countries, with optimal glycemic control being important in reducing the risk of CKD progression and related death. However, assessing glycemic control in advanced CKD and dialysis patients can be challenging. Continuous glucose monitoring (CGM) systems provide an alternative and more reliable method of glycemic assessment, although further studies are needed to confirm their accuracy and cost-effectiveness in this population.
FRONTIERS IN ENDOCRINOLOGY
(2022)
Article
Biochemistry & Molecular Biology
Shuqin Mei, Lin Li, Xiangjun Zhou, Cheng Xue, Man J. Livingston, Qingqing Wei, Bing Dai, Zhiguo Mao, Changlin Mei, Zheng Dong
Summary: Diabetes enhances kidney fibrosis by enhancing HIF-1 activation, leading to impaired kidney repair. In diabetic mice, unilateral ureteral obstruction induces more renal fibrosis, apoptosis, and interstitial macrophage infiltration. High glucose-conditioned renal tubular cells show higher expression of fibrosis marker protein under hypoxia, which is mediated by increased HIF-1α expression. Knockout of proximal tubule-specific HIF-1α attenuates fibrosis induced by UUO in diabetic mice kidneys.
Review
Nutrition & Dietetics
Enav Yefet, Liron Bar, Ido Izhaki, Rula Iskander, Manal Massalha, Johnny S. S. Younis, Zohar Nachum
Summary: This systematic review and meta-analysis of randomized controlled trials aimed to evaluate the effects of probiotic supplements on glycemic control and metabolic parameters in women with gestational diabetes mellitus (GDM). The results showed that compared to placebo, women receiving probiotic supplements had significantly lower fasting serum glucose, insulin, homeostatic model assessment for insulin resistance (HOMA-IR), triglycerides, total cholesterol, and VLDL levels. The use of probiotic supplements containing Lactobacillus acidophilus also led to decreased neonatal birth weight.
Article
Urology & Nephrology
James Ling, Jack K. C. Chung Ng, Eric S. H. Lau, Ronald C. W. Ma, Alice P. S. Kong, Andrea O. Y. Luk, Jeffrey S. S. Kwok, Cheuk-Chun Szeto, Juliana C. N. Chan, Elaine Chow
Summary: This study evaluated the relationship between HbA1c and CGM metrics in patients with moderate-to-advanced CKD. The correlations between glucose management indicator (GMI) and HbA1c attenuated with advancing CKD. HbA1c showed significant correlation with some CGM metrics in G3b and G4, but not in G5.
KIDNEY INTERNATIONAL REPORTS
(2022)
Review
Endocrinology & Metabolism
Carol Chiung-Hui Peng, Yu-Kang Tu, Gin Yi Lee, Rachel Huai-En Chang, Yuting Huang, Khulood Bukhari, Yao-Chou Tsai, Yunting Fu, Huei-Kai Huang, Kashif M. Munir
Summary: Proton pump inhibitors (PPI) therapy can improve glycemic control among individuals with diabetes, but it does not decrease the risk of incident diabetes.
JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM
(2021)
Article
Psychiatry
Anna C. Queiroz de Medeiros, Lucia de F. C. Pedrosa, Maria E. Yamamoto
BRAZILIAN JOURNAL OF PSYCHIATRY
(2019)
Article
Nutrition & Dietetics
Georgina Gomez, Regina Mara Fisberg, Agatha Nogueira Previdelli, Cristiane Hermes Sales, Irina Kovalskys, Mauro Fisberg, Marianella Herrera-Cuenca, Lilia Yadira Cortes Sanabria, Martha Cecilia Yepez Garcia, Rossina Gabriella Pareja Torres, Attilio Rigotti, Viviana Guajardo, Iona Zalcman Zimberg, Anne Chinnock, Ana Gabriela Murillo, Juan Carlos Brenes
Article
Microbiology
Marina Padilha, Niels Banhos Danneskiold-Samsoe, Asker Brejnrod, Christian Hoffmann, Vanessa Pereira Cabral, Julia de Melo Iaucci, Cristiane Hermes Sales, Regina Mara Fisberg, Ramon Vitor Cortez, Susanne Brix, Carla Romano Taddei, Karsten Kristiansen, Susana Marta Isay Saad
Article
Nutrition & Dietetics
Mariane de Mello Fontanelli, Renata Micha, Cristiane Hermes Sales, Junxiu Liu, Dariush Mozaffarian, Regina Mara Fisberg
EUROPEAN JOURNAL OF NUTRITION
(2020)
Article
Multidisciplinary Sciences
Raphaela Cecilia The Maia de Arruda Falcao, Clwlia de Oliveira Lyra, Celia Marcia Medeiros de Morais, Liana Galvao Bacurau Pinheiro, Lucia Fatima Campos Pedrosa, Severina Carla Vieira Cunha Lima, Karine Cavalcanti Mauricio Sena-Evangelista
Article
Public, Environmental & Occupational Health
Mariane de M. Fontanelli, Cristiane H. Sales, Michelle A. de Castro, Regina M. Fisberg
Summary: The study found a growing trend in the consumption of grain foods meeting the <= 10:1 ratio from 2003 to 2015, but this consumption remains far below recommended levels. Sociodemographic factors such as older age, female gender, higher education levels, and higher family income were associated with a higher likelihood of consuming grain foods meeting the ratio, while individuals of black, brown, or indigenous ethnicity were less likely to consume these foods.
PUBLIC HEALTH NUTRITION
(2021)
Article
Cardiac & Cardiovascular Systems
Josivan Gomes Lima, Lucia Helena C. Nobrega, Flora Tamires Moura Bandeira, Andre Gustavo Pires Sousa, Taisa Barreto Medeiros de Araujo Macedo, Ana Claudia Cavalcante Nogueira, Antonio Fernandes de Oliveira Filho, Renato Jorge Alves, Maria Helane Costa Gurgel Castelo, Fabiana Maria Silva Coelho, Rayana Elias Maia, Debora Nobrega Lima, Ana Rafaela de Souza Timoteo, Julliane Tamara Araujo de Melo Campos
Summary: This study described a novel pathogenic intronic mutation in GPIHBP1 in patients from the Northeast region of Brazil, suggesting the occurrence of a founder effect. This mutation is likely to alter GPIHBP1 pre-mRNA processing and affect around 50% of the domain structure.
Article
Public, Environmental & Occupational Health
Regina Mara Fisberg, Ana Carolina Barco Leme, Agatha Previdelli, Aline Veroneze de Mello, Angela Graciela Martinez, Cristiane Hermes Sales, Georgina Gomez, Irina Kovalskys, Marianella Herrera-Cuenca, Lilia Yadira Cortes Sanabria, Martha Cecilia Yepez Garcia, Rossina G. Torres, Attilio Rigotti, Mauro Fisberg
Summary: The study based on the ELANS data aimed to investigate the top sources of energy, nutrients-to-limit, and total gram amount consumed by Latin Americans. The findings showed that rice, yeast breads, and turnovers were the top sources of energy, while fruit drinks, other 100% juice, and rice were the most consumed in terms of total gram amount. Added sugars mainly came from other 100% juice and fruit drinks, while SFA mostly came from turnovers, cheese, and pizza. The top sources of Na included rice, soups, and rice mixed dishes. The identification of these sources is crucial for developing strategies to improve nutrient intake among this population.
PUBLIC HEALTH NUTRITION
(2021)
Article
Environmental Sciences
Ana Carolina Barco Leme, Regina Mara Fisberg, Aline Veroneze de Mello, Cristiane Hermes Sales, Gerson Ferrari, Jess Haines, Attilo Rigotti, Georgina Gomez, Irina Kovalskys, Lilia Yadira Cortes Sanabria, Marianella Herrera-Cuenca, Martha Cecilia Yepez Garcia, Rossina G. Pareja, Mauro Fisberg
Summary: The study found that in most Latin American countries, the intake inadequacy of key nutrients such as vitamin A, D, C, E, dietary folate, calcium, iron, magnesium, potassium, and fiber exceeded 50%, with the exception of vitamin C at 39%. Milk, cheese, seafoods, breads, and fruit juices/drinks were identified as the main food sources of these shortfall nutrients.
INTERNATIONAL JOURNAL OF ENVIRONMENTAL RESEARCH AND PUBLIC HEALTH
(2021)
Article
Nutrition & Dietetics
Cristiane Hermes Sales, Marcelo Macedo Rogero, Flavia Mori Sarti, Regina Mara Fisberg
Summary: The study revealed that residents of Sao Paulo had a low prevalence of anemia, iron deficiency, and IDA. However, female adolescents and adults were more vulnerable to depleted iron stores, while male adults and older adults had a considerable prevalence of iron overload. Various sociodemographic factors influenced these parameters.
Letter
Endocrinology & Metabolism
Bartira Miridan Xavier Cortez Rodrigues Reboucas Feijo, Roberto Moreno Mendonca, Eryvaldo Socrates Tabosa Egito, Debora Nobrega Lima, Julliane Tamara Araujo de Melo Campos, Josivan Gomes Lima
CLINICAL ENDOCRINOLOGY
(2022)
Review
Biochemistry & Molecular Biology
Julliane Tamara Araujo de Melo Campos, Matheus Sena de Oliveira, Luisa Pessoa Soares, Katarina Azevedo de Medeiros, Leonardo Rene dos Santos Campos, Josivan Gomes Lima
Summary: Classical and progeroid congenital lipodystrophies are rare diseases caused by pathogenic variants in genes, leading to various issues such as impaired adipose tissue homeostasis, insulin resistance, diabetes, dyslipidemia, and inflammation. Studying the link between adipogenesis and DNA repair in these diseases is of great significance.
GENETICS AND MOLECULAR BIOLOGY
(2022)
Article
Pharmacology & Pharmacy
Raul D. Santos, Alberto Lorenzatti, Pablo Corral, Juan Patricio Nogueira, Alberto M. Cafferata, Daniel Aimone, Charles M. Lourenco, Maria Cristina Izar, Josivan G. Lima, Ana Maria Lottenberg, Rodrigo Alonso, Karla Garay, Alvaro Ruiz Morales, Hernando Vargas-Uricoechea, Christian A. Colon Pena, Alejandro Roman-Gonzalez
Summary: Familial chylomicronemia syndrome (FCS) is a rare genetic disorder characterized by late diagnosis, heterogeneity in disease progression, and increased risk of pancreatitis and secondary diabetes. Molecular diagnosis is uncommon, with loss of function variants on the lipoprotein lipase gene being a common etiology. Low awareness among health professionals contributes to inadequate care for FCS patients.
JOURNAL OF CLINICAL LIPIDOLOGY
(2021)
Article
Public, Environmental & Occupational Health
Diogo Vale, Celia Marcia Medeiros de Morais, Lucia de Fatima Campos Pedrosa, Maria Angela Fernandes Ferreira, Angelo Giuseppe Roncalli da Costa Oliveira, Clelia de Oliveira Lyra
CIENCIA & SAUDE COLETIVA
(2019)
Article
Nutrition & Dietetics
Eduardo Paixao Silva, Erika Paula Silva Freitas, Isabelli Luara Costa Silva, Giovanna Melo Carvalho, Jainara da Silval Soares, Josivan Gomes Lima, Lucia de Fatima Campos Pedrosa, Karine Cavalcanti Mauricio Sena-Evangelista
NUTRICION CLINICA Y DIETETICA HOSPITALARIA
(2019)