Article
Microbiology
Nuomin, Riyang Baek, Takeshi Tsuruta, Naoki Nishino
Summary: Milk can be categorized into two types, A1 and A2, based on the fi-casein variants. This study compared the effects of feeding A1 casein, A2 casein, mixed casein, soy protein isolate, and egg white on the cecum microbiota and fermentation in mice. The results showed that mice fed A1 casein had higher levels of acetic acid and greater relative abundances of Muribaculaceae and Desulfovibrionaceae. However, the differences among the mice fed A1, A2, and mixed caseins were not significant compared to the differences observed among the three caseins, soy, and egg feedings. Evaluating the distinct modulatory effects on gut environments, the differences between milk, soy, and egg proteins are worth further investigation.
Review
Biochemistry & Molecular Biology
Dibyendu Das, Mir Ekbal Kabir, Sanjib Sarkar, Sawlang Borsingh Wann, Jatin Kalita, Prasenjit Manna
Summary: Soy protein has anti-diabetic properties and can prevent and control abnormalities related to diabetes, with a significant correlation between soy protein intake and lower prevalence of diabetes. Soy-derived peptides can also trigger anti-diabetic responses by modulating cell signaling pathways.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2022)
Article
Nutrition & Dietetics
Keiichi Koshinaka, Asuka Honda, Rihei Iizumi, Yuto Miyazawa, Kentaro Kawanaka, Akiko Sato
Summary: According to the Digestible Indispensable Amino Acid Score (DIAAS), egg white protein (EGG) has a high score and has been found to accelerate skeletal muscle gain more effectively than casein (CAS) and whey (WHE) under anabolism-dominant conditions, regardless of its arginine-rich composition.
Review
Agriculture, Dairy & Animal Science
B. G. Carter, N. Cheng, R. Kapoor, G. H. Meletharayil, M. A. Drake
Summary: Milk can be fractionated into various components using microfiltration technology, offering unique functional and nutritional benefits for new product development. Microfiltration shows promise in improving efficiency and quality in dairy production, particularly in cheese making. These new ingredients could provide unique functional and flavor properties in food applications, presenting potential growth opportunities in response to consumer demand for safe and nutritious foods.
JOURNAL OF DAIRY SCIENCE
(2021)
Article
Endocrinology & Metabolism
Brandon J. Gheller, Jamie E. Blum, Esther W. Lim, Michal K. Handzlik, Ern Hwei Hannah Fong, Anthony C. Ko, Shray Khanna, Molly E. Gheller, Erica L. Bender, Matthew S. Alexander, Patrick J. Stover, Martha S. Field, Benjamin D. Cosgrove, Christian M. Metallo, Anna E. Thalacker-Mercer
Summary: Skeletal muscle regeneration requires MuSCs, MPCs, and a myogenic program, with serine/glycine playing a crucial role in MuSC/MPC function.
MOLECULAR METABOLISM
(2021)
Review
Nutrition & Dietetics
Justin Dela Cruz, David Kahan
Summary: Research on the effects of pre-sleep casein protein supplementation on metabolism, appetite, and other non-muscular parameters is limited, with data showing limited effects. Further research is needed to clarify the observed relationships.
Article
Biochemistry & Molecular Biology
Dibyendu Das, Nazim Uddin Afzal, Sawlang Borsingh Wann, Jatin Kalita, Prasenjit Manna
Summary: The present study investigated the antidiabetic potential of protein isolates from Hawaijar (HPI), a popular fermented soybean food of North-East India. Treatment with HPI significantly upregulated glucose uptake, glucose utilization, glucose-6-phosphate, and stimulated PI3K/AKT/GLUT4 pathway in high-glucose (HG) -treated myotubes. SDS-PAGE and immunoblotting analyses of HPI showed the reduction and/or absence of various subunits of 7S and 11S globulin protein and appearance of new proteins compared to respective non-fermented soy protein isolates.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2023)
Article
Physiology
Sonia Metayer-Coustard, Sophie Tesseraud, Christophe Praud, David Royer, Thierry Bordeau, Edouard Coudert, Estelle Cailleau-Audouin, Estelle Godet, Joel Delaveau, Elisabeth Le Bihan-Duval, Cecile Berri
Summary: Divergent selection on Pectoralis major pHu in chickens resulted in the creation of pHu+ and pHu- lines, with differences in carbohydrate and protein metabolism which likely affect muscle growth and energy storage capabilities. These differences were already present at hatching, indicating early mechanisms involved in the establishment of phenotypes.
FRONTIERS IN PHYSIOLOGY
(2021)
Article
Nutrition & Dietetics
Jerome Salles, Christelle Guillet, Olivier Le Bacquer, Carmen Malnero-Fernandez, Christophe Giraudet, Veronique Patrac, Alexandre Berry, Philippe Denis, Corinne Pouyet, Marine Gueugneau, Yves Boirie, Heidi Jacobs, Stephane Walrand
Summary: Old rats were found to use pea protein with the same efficiency as casein or whey proteins, with similar effects on body composition, tissue weight, skeletal muscle protein synthesis and degradation. This suggests that using plant-based proteins could help older individuals diversify their protein sources and meet nutritional intake recommendations more easily.
Article
Chemistry, Medicinal
Hye-Won Yang, Seyeon Oh, Dong-Min Chung, Minyoung Seo, Shin Jae Park, You-Jin Jeon, Kyunghee Byun, BoMi Ryu
Summary: This study evaluated the effect of Ishige okamurae extract (IO) and its component, Ishophloroglucin A (IPA), on muscle atrophy induced by dexamethasone. The results showed that IO and IPA supplementation improved muscle weight and width, enhanced grip strength, and regulated muscle protein metabolism by modulating gene expression related to protein synthesis, degradation, and muscle growth activation or inhibition.
Article
Food Science & Technology
Yudong Wang, Hao Yan, Yang Zhuang, Yuxin Tian, Hong Yang
Summary: The study aimed to investigate the impact of soy protein isolate (SPI), egg white protein (EW), and whey protein isolate (WPI) on the flavor characteristics of silver carp surimi. It was found that SPI had significant effects on volatile odor compounds (VOCs) in surimi gels, while EW had a relatively lower effect. All three proteins reduced undesirable VOCs and fatty acids in the surimi, with SPI and EW also reducing free amino acids (FAAs). Most VOCs had a positive correlation with FAAs in surimi with SPI or WPI, while a negative correlation was observed with EW. Furthermore, SPI had higher fatty acid levels and a stronger correlation with certain VOCs compared to EW or WPI. The addition of NMPs was found to modify the flavor of surimi gels and mask the fishy odor, with 2% or 4% being the appropriate amount.
LWT-FOOD SCIENCE AND TECHNOLOGY
(2023)
Article
Nutrition & Dietetics
Teresa F. Wegrzyn, Sharon Henare, Natalie Ahlborn, Noha Ahmed Nasef, Linda M. Samuelsson, Simon M. Loveday
Summary: The study found that there were differences in postprandial plasma amino acid response and urine metabolite fingerprints between soy-dairy protein blends and whey protein in older adults. However, overall, the protein source did not significantly impact the postprandial plasma amino acid response.
BRITISH JOURNAL OF NUTRITION
(2022)
Article
Nutrition & Dietetics
Francina J. Dijk, Zandrie Hofman, Yvette C. Luiking, Matthew J. W. Furber, Justin D. Roberts, Ardy van Helvoort, Miriam van Dijk
Summary: This study aimed to compare the effect of P4, whey protein, and casein on muscle protein synthesis (MPS). The results showed that P4 had a similar MPS response to whey protein in aged mice after fasting.
Article
Food Science & Technology
Zhi-hui Sun, Ming-jing Yao, Xin Bian, Qing-qi Guo, Hua-nan Guan, Yang Yang, Bing Wang, Yan-guo Shi, Wojciech Piekoszewski, Xiao-wan Yang, Na Zhang
Summary: The addition of soy protein hydrolysate (SPH) to infant formula powder significantly enhances the proliferation of probiotics and increases antibacterial activity, making it a promising protein alternative in infant formula powder.
FOOD RESEARCH INTERNATIONAL
(2021)
Article
Physiology
Mon-Chien Lee, Yi-Ju Hsu, Fang-Yu Wu, Chi-Chang Huang, Hsueh-Yu Li, Wen-Chyuan Chen
Summary: This study found that the combination of soy protein supplementation and resistance training had the best effect on improving muscle strength, physical performance, and functional activity in aging mice, compared to individual applications. This strategy has a positive impact on overall health and physical fitness improvement among the elderly.
FRONTIERS IN PHYSIOLOGY
(2022)
Article
Nutrition & Dietetics
Sarah K. Kirschner, Nicolaas E. P. Deutz, Renate Jonker, Steven W. M. Olde Damink, Rajesh Harrykissoon, Anthony J. Zachria, Srinivasan Dasarathy, Marielle P. K. J. Engelen
Summary: This study found that COPD patients have abnormalities in intestinal function, which worsen with disease severity and are associated with a decrease in quality of life.
CLINICAL NUTRITION
(2021)
Article
Physiology
Clayton L. Cruthirds, Nicolaas E. P. Deutz, Gerdien C. Ligthart-Melis, Sunday Y. Simbo, Marielle P. K. J. Engelen
Summary: Older adults with COPD experience disturbances in gut function and whole body protein metabolism during and after exercise, particularly in cases of exercise-induced hypoxia.
JOURNAL OF APPLIED PHYSIOLOGY
(2021)
Article
Nutrition & Dietetics
Sindhu Kashyap, Nirupatna Shivakumar, Veerasamy Sejian, Nicolaas E. P. Deutz, Thomas Preston, Sheshshayee Sreeman, Sarita Devi, Anura Kurpad
Summary: The study aimed to determine the true ileal indispensable amino acid digestibility of intrinsically labeled goat milk protein in South Indian women of reproductive age and measure the intestinal absorption of amino acid and inert sugar. Results showed that the digestibility of goat milk protein in South Indian women with normal intestinal function was comparable to healthy French adults.
AMERICAN JOURNAL OF CLINICAL NUTRITION
(2021)
Article
Nutrition & Dietetics
Nicolaas E. P. Deutz, Pierre Singer, Raven A. Wierzchowska-McNew, Marina V. Viana, Itai A. Ben-David, Olivier Pantet, John J. Thaden, Gabriella A. M. Ten Have, Marielle P. K. J. Engelen, Mette M. Berger
Summary: Severely disturbed AA metabolism and increased WBP were observed in critically ill ICU patients compared to healthy controls. Lower phase-angle and higher CRP levels were also noted in the ICU patients. Specific AA pathways were affected depending on disease severity, highlighting the importance of comprehensive metabolic phenotyping in improving the health of critically ill patients.
CLINICAL NUTRITION
(2021)
Article
Nutrition & Dietetics
Sarah K. Kirschner, Nicolaas E. P. Deutz, Iris Rijnaarts, Tiffany J. Smit, Daniel J. Larsen, Marielle P. K. J. Engelen
Summary: The study found impaired protein digestion and absorption, altered plasma SCFA concentrations in CHF patients, which are associated with reduced muscle and cognitive health as well as overall well-being. More research is needed to implement strategies to improve intestinal function in CHF and to explore the mechanisms underlying its connection with other systemic manifestations.
JOURNAL OF PARENTERAL AND ENTERAL NUTRITION
(2022)
Review
Nutrition & Dietetics
Nina Kaegi-Braun, Montserrat Faessli, Fiona Kilchoer, Saranda Dragusha, Pascal Tribolet, Filomena Gomes, Celine Bretscher, Sara Germann, Nicolaas E. Deutz, Zeno Stanga, Beat Mueller, Philipp Schuetz
Summary: Nutritional support has been shown to significantly improve clinical outcomes in malnourished medical inpatients, reducing mortality, unplanned hospital readmissions, and length of hospital stay. High-protein strategies and long-term nutritional interventions are most effective in improving patient outcomes.
CLINICAL NUTRITION ESPEN
(2021)
Article
Computer Science, Information Systems
Anurag Das, Bobak Mortazavi, Seyedhooman Sajjadi, Theodora Chaspari, Laura E. Ruebush, Nicolaas E. Deutz, Gerard L. Cote, Ricardo Gutierrez-Osuna
Summary: This study examines the impact of additional dietary biomarkers in blood on macronutrient prediction and finds that they improve prediction performance compared to using continuous glucose monitors alone. The findings suggest a potential solution to the problem of diet monitoring and may facilitate the development of automated methods for monitoring nutritional intake.
IEEE JOURNAL OF BIOMEDICAL AND HEALTH INFORMATICS
(2022)
Article
Nutrition & Dietetics
Raven A. Wierzchowska-McNew, Marielle P. K. J. Engelen, John J. Thaden, Gabriella A. M. ten Have, Nicolaas E. P. Deutz
Summary: This study aimed to investigate the association between obesity, sex, and sex-by-obesity interaction on whole-body arginine kinetics. The findings suggest that alterations in arginine metabolism are present in morbid obesity, but further research is needed to explore the factors related to these changes.
AMERICAN JOURNAL OF CLINICAL NUTRITION
(2022)
Article
Nutrition & Dietetics
Katherine L. Ford, Claire F. Trottier, Wendy V. Wismer, Michael B. Sawyer, Mario Siervo, Nicolaas E. P. Deutz, Carla M. Prado, Helen Vallianatos
Summary: This qualitative study explored the dietary decisions made by patients with colorectal cancer (CRC) starting chemotherapy. The results showed that patients' dietary choices were influenced by medical factors, health beliefs, fixed diets, and external influences. Understanding these factors can guide healthcare providers in providing tailored dietary support for CRC patients.
JOURNAL OF THE ACADEMY OF NUTRITION AND DIETETICS
(2023)
Article
Geriatrics & Gerontology
Wayne W. Campbell, Nicolaas E. P. Deutz, Elena Volpi, Caroline M. Apovian
Summary: This narrative review discusses the impact of dietary protein intake on muscle-related attributes of older adults. Insufficient protein intake exacerbates age-related reductions in muscle size, quality, and function. Adequate protein intake promotes muscle size and function, with observational studies suggesting higher protein intake may enhance muscle strength and function. Higher protein intake benefits lean body mass changes under stress conditions. Specialized protein supplements can help attenuate muscle loss in older adults with medical conditions or acute illness. Animal protein sources are preferred for sarcopenia-related parameters. The quantity, quality, and patterning of dietary protein intake are important for supporting muscle size and function in older adults.
JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES
(2023)
Editorial Material
Nutrition & Dietetics
Nathalie Delzenne, Nicolaas E. Deutz, Dileep N. Lobo, George Grimble
Summary: In this education paper, advice is given on successful scientific grant writing. The paper emphasizes the importance of defining research hypothesis, fulfilling technical aspects, and understanding the requirements before writing the proposal. It also highlights the need to develop a timeline, create an attractive summary, and set SMART research objectives. Additionally, the paper emphasizes the importance of making the proposal understandable to non-experts while providing sufficient details for experts.
CLINICAL NUTRITION ESPEN
(2023)
Article
Nutrition & Dietetics
Nicolaas E. Deutz, Nathalie Delzenne, George Grimble, Dileep N. Lobo
Summary: Publishing a scientific paper is a challenging process that depends on the quality of study design, research questions, clear primary endpoints, and data from a large population. Before submission, it is important to meet ethical requirements, register in public databases, and declare any conflicts of interest. The structure of the manuscript includes sections for introduction, materials and methods, results, discussion, and an abstract that summarizes all aspects concisely. The publication process involves editors, reviewers, and publishers, with the initial impression being crucial for review. Thoughtful responses to reviewers' feedback are necessary for revisions. The goal is acceptance and publication of the paper.
CLINICAL NUTRITION ESPEN
(2023)
Article
Nutrition & Dietetics
George Grimble, Dileep N. Lobo, Nathalie Delzenne, Nicolaas E. Deutz
Summary: When presenting a paper, it is important to tailor your presentation to the audience's knowledge level and the title and abstract you submitted. Keep the talk simple and avoid complexity. Stick to the scheduled time and present the information in a concise manner. Make sure your slides are clear and informative, readable from a distance. Practice the talk beforehand, preferably with colleagues, and be prepared to make any necessary changes. Familiarize yourself with the content so you can relax and enjoy the experience.
CLINICAL NUTRITION ESPEN
(2023)
Article
Nutrition & Dietetics
Dileep N. Lobo, George Grimble, Nathalie Delzenne, Nicolaas E. Deutz
Summary: There are potential pitfalls in the publication process that researchers may encounter, whether knowingly or unknowingly. Disregarding publication governance can be risky and harm the reputation of authors and co-authors, even if the errors are unintentional. This article highlights these pitfalls, introduces relevant rules in research and publishing, and guides readers on how to avoid stumbling on the path to publication.
CLINICAL NUTRITION ESPEN
(2023)
Review
Nutrition & Dietetics
Nina Kaegi-Braun, Fiona Kilchoer, Saranda Dragusha, Carla Gressies, Montserrat Faessli, Filomena Gomes, Nicolaas E. Deutz, Zeno Stanga, Beat Mueller, Philipp Schuetz
Summary: This systematic review suggests that postdischarge nutritional support in the outpatient setting can lower all-cause mortality, increase nutritional intake, and improve body weight in malnourished patients.
CLINICAL NUTRITION
(2022)