Hepatosplenic Candidiasis Imaged With F-18 FDG PET/CT

We report a case of hepatosplenic candidiasis imaged with F-18 fluorodeoxyglucose positron emission tomography/computed tomography (FDG PET/CT). A 22-year-old man receiving treatment for acute myeloid leukemia presented with fever. Hepatosplenic candidiasis was diagnosed based on the presence of hepatosplenic micro abscesses on CT. Fever persisted in spite of fluconazole treatment. F-18 FDG PET/CT scan was performed to rule out persistent hepatosplenic infection or other organ involvement. PET showed multiple intense uptake foci throughout the liver and spleen. The fungicidal drug was changed. The patient improved. We conclude that it would be interesting to investigate the use of F-18 FDG PET/CT in the work-up of systemic candidiasis.