The Cryptococcus neoformans Capsule: a Sword and a Shield

A Major Role for Capsule-Independent Phagocytosis-Inhibitory Mechanisms in Mammalian Infection by Cryptococcus neoformans

(2011) Cheryl D. Chun et al.   Cell Host & Microbe

Evaluation of a Novel Point-of-Care Cryptococcal Antigen Test on Serum, Plasma, and Urine From Patients With HIV-Associated Cryptococcal Meningitis

(2011) J. N. Jarvis et al.   CLINICAL INFECTIOUS DISEASES

The Casein Kinase I Protein Cck1 Regulates Multiple Signaling Pathways and Is Essential for Cell Integrity and Fungal Virulence in Cryptococcus neoformans

(2011) Yina Wang et al.   EUKARYOTIC CELL

Wsp1, a GBD/CRIB Domain-Containing WASP Homolog, Is Required for Growth, Morphogenesis, and Virulence of Cryptococcus neoformans

(2011) Gui Shen et al.   EUKARYOTIC CELL

Multiple Roles of Ypd1 Phosphotransfer Protein in Viability, Stress Response, and Virulence Factor Regulation in Cryptococcus neoformans

(2011) Jang-Won Lee et al.   EUKARYOTIC CELL

A Flucytosine-Responsive Mbp1/Swi4-Like Protein, Mbs1, Plays Pleiotropic Roles in Antifungal Drug Resistance, Stress Response, and Virulence of Cryptococcus neoformans

(2011) Min-Hee Song et al.   EUKARYOTIC CELL

Cell Wall Chitosan Is Necessary for Virulence in the Opportunistic Pathogen Cryptococcus neoformans

(2011) Lorina G. Baker et al.   EUKARYOTIC CELL

Cryptococcal Titan Cell Formation Is Regulated by G-Protein Signaling in Response to Multiple Stimuli

(2011) Laura H. Okagaki et al.   EUKARYOTIC CELL

Iron influences the abundance of the iron regulatory protein Cir1 in the fungal pathogenCryptococcus neoformans

(2011) Won Hee Jung et al.   FEBS LETTERS

Identification of a Zds-like gene ZDS3 as a new mediator of stress resistance, capsule formation and virulence of the human pathogenic yeast Cryptococcus neoformans

(2011) Zhongming Li et al.   FEMS YEAST RESEARCH

Nitrogen Metabolite Repression of Metabolism and Virulence in the Human Fungal PathogenCryptococcus neoformans

(2011) I. Russel Lee et al.   GENETICS

A Novel Specificity Protein 1 (SP1)-like Gene Regulating Protein Kinase C-1 (Pkc1)-dependent Cell Wall Integrity and Virulence Factors inCryptococcus neoformans

(2011) Amos Adler et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Evidence for branching in cryptococcal capsular polysaccharides and consequences on its biological activity

(2011) Radames J. B. Cordero et al.   MOLECULAR MICROBIOLOGY

Role for Golgi reassembly and stacking protein (GRASP) in polysaccharide secretion and fungal virulence

(2011) Lívia Kmetzsch et al.   MOLECULAR MICROBIOLOGY

The copper regulon of the human fungal pathogen Cryptococcus neoformans H99

(2011) Chen Ding et al.   MOLECULAR MICROBIOLOGY

Hrk1 Plays Both Hog1-Dependent and -Independent Roles in Controlling Stress Response and Antifungal Drug Resistance in Cryptococcus neoformans

(2011) Seo-Young Kim et al.   PLoS One

Cryptococcus neoformans Mediator Protein Ssn8 Negatively Regulates Diverse Physiological Processes and Is Required for Virulence

(2011) Lin-Ing Wang et al.   PLoS One

Cryptococcus neoformans Capsular Enlargement and Cellular Gigantism during Galleria mellonella Infection

(2011) Rocío García-Rodas et al.   PLoS One

Unique Evolution of the UPR Pathway with a Novel bZIP Transcription Factor, Hxl1, for Controlling Pathogenicity of Cryptococcus neoformans

(2011) Seon Ah Cheon et al.   PLoS Pathogens

Phospholipids Trigger Cryptococcus neoformans Capsular Enlargement during Interactions with Amoebae and Macrophages

(2011) Cara J. Chrisman et al.   PLoS Pathogens

Toward an Integrated Model of Capsule Regulation in Cryptococcus neoformans

(2011) Brian C. Haynes et al.   PLoS Pathogens

Cryptococcus neoformans responds to mannitol by increasing capsule size in vitro and in vivo

(2010) Allan Jefferson Guimarães et al.   CELLULAR MICROBIOLOGY

Galactoxylomannans from Cryptococcus neoformans VarietiesneoformansandgrubiiAre Structurally and Antigenically Variable

(2010) Magdia De Jesus et al.   EUKARYOTIC CELL

Comparative Transcriptome Analysis Reveals Novel Roles of the Ras and Cyclic AMP Signaling Pathways in Environmental Stress Response and Antifungal Drug Sensitivity in Cryptococcus neoformans

(2010) Shinae Maeng et al.   EUKARYOTIC CELL

Cryptococcus neoformans Histone Acetyltransferase Gcn5 Regulates Fungal Adaptation to the Host

(2010) Teresa R. O'Meara et al.   EUKARYOTIC CELL

The GATA-type transcriptional activator Gat1 regulates nitrogen uptake and metabolism in the human pathogen Cryptococcus neoformans

(2010) Lívia Kmetzsch et al.   FUNGAL GENETICS AND BIOLOGY

Comparative Transcriptome Analysis of the CO2 Sensing Pathway Via Differential Expression of Carbonic Anhydrase in Cryptococcus neoformans

(2010) M. S. Kim et al.   GENETICS

Survival Defects of Cryptococcus neoformans Mutants Exposed to Human Cerebrospinal Fluid Result in Attenuated Virulence in an Experimental Model of Meningitis

(2010) A. Lee et al.   INFECTION AND IMMUNITY

Receptor-independent Ambient pH Signaling by Ubiquitin Attachment to Fungal Arrestin-like PalF

(2010) América Hervás-Aguilar et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Ab binding alters gene expression in Cryptococcus neoformans and directly modulates fungal metabolism

(2010) Erin E. McClelland et al.   JOURNAL OF CLINICAL INVESTIGATION

Pleiotropic function of intersectin homologue Cin1 in Cryptococcus neoformans

(2010) Gui Shen et al.   MOLECULAR MICROBIOLOGY

KREgenes are required for β-1,6-glucan synthesis, maintenance of capsule architecture and cell wall protein anchoring inCryptococcus neoformans

(2010) Nicole M. Gilbert et al.   MOLECULAR MICROBIOLOGY

The iron-responsive, GATA-type transcription factor cir1 influences mating in Cryptococcus neoformans

(2010) Won Hee Jung et al.   MOLECULES AND CELLS

Ctr2 Links Copper Homeostasis to Polysaccharide Capsule Formation and Phagocytosis Inhibition in the Human Fungal Pathogen Cryptococcus neoformans

(2010) Cheryl D. Chun et al.   PLoS One

An Extensive Circuitry for Cell Wall Regulation in Candida albicans

(2010) Jill R. Blankenship et al.   PLoS Pathogens

Interaction of Cryptococcus neoformans Rim101 and Protein Kinase A Regulates Capsule

(2010) Teresa R. O'Meara et al.   PLoS Pathogens

Cryptococcal Cell Morphology Affects Host Cell Interactions and Pathogenicity

(2010) Laura H. Okagaki et al.   PLoS Pathogens

HapX Positively and Negatively Regulates the Transcriptional Response to Iron Deprivation in Cryptococcus neoformans

(2010) Won Hee Jung et al.   PLoS Pathogens

Fungal Cell Gigantism during Mammalian Infection

(2010) Oscar Zaragoza et al.   PLoS Pathogens

Estimation of the current global burden of cryptococcal meningitis among persons living with HIV/AIDS

(2009) Benjamin J Park et al.   AIDS

How Sweet it is! Cell Wall Biogenesis and Polysaccharide Capsule Formation inCryptococcus neoformans

(2009) Tamara Lea Doering   Annual Review of Microbiology

The structure of Cryptococcus neoformans galactoxylomannan contains β-d-glucuronic acid

(2009) Christian Heiss et al.   CARBOHYDRATE RESEARCH

Recruitment of a chromatin remodelling complex by the Hog1 MAP kinase to stress genes

(2009) Glòria Mas et al.   EMBO JOURNAL

Production of Extracellular Polysaccharides byCAPMutants ofCryptococcus neoformans

(2009) Jan Grijpstra et al.   EUKARYOTIC CELL

Regulatory Diversity ofTUP1inCryptococcus neoformans

(2009) Hyeseung Lee et al.   EUKARYOTIC CELL

Role for Chitin and Chitooligomers in the Capsular Architecture ofCryptococcus neoformans

(2009) Fernanda L. Fonseca et al.   EUKARYOTIC CELL

Remodeling of Global Transcription Patterns ofCryptococcus neoformansGenes Mediated by the Stress-Activated HOG Signaling Pathways

(2009) Young-Joon Ko et al.   EUKARYOTIC CELL

Conservation of the Sterol Regulatory Element-Binding Protein Pathway and Its Pathobiological Importance inCryptococcus neoformans

(2009) Yun C. Chang et al.   EUKARYOTIC CELL

Chitinases Are Essential for Sexual Development but Not Vegetative Growth inCryptococcus neoformans

(2009) Lorina G. Baker et al.   EUKARYOTIC CELL

Iron Activates In Vivo DNA Binding ofSchizosaccharomyces pombeTranscription Factor Fep1 through Its Amino-Terminal Region

(2009) Mehdi Jbel et al.   EUKARYOTIC CELL

Identification ofENA1as a Virulence Gene of the Human Pathogenic FungusCryptococcus neoformansthrough Signature-Tagged Insertional Mutagenesis

(2009) Alexander Idnurm et al.   EUKARYOTIC CELL

Cryptococcus neoformans cryoultramicrotomy and vesicle fractionation reveals an intimate association between membrane lipids and glucuronoxylomannan

(2009) Débora L. Oliveira et al.   FUNGAL GENETICS AND BIOLOGY

Molecular Evidence That the Range of the Vancouver Island Outbreak ofCryptococcus gattiiInfection Has Expanded into the Pacific Northwest in the United States

(2009) Edmond J. Byrnes III et al.   JOURNAL OF INFECTIOUS DISEASES

Recruitment of the ESCRT Machinery to a Putative Seven-Transmembrane-Domain Receptor Is Mediated by an Arrestin-Related Protein

(2009) A. Herrador et al.   MOLECULAR AND CELLULAR BIOLOGY

Sec6-dependent sorting of fungal extracellular exosomes and laccase ofCryptococcus neoformans

(2009) John Panepinto et al.   MOLECULAR MICROBIOLOGY

Phenotypic heterogeneity in expression of epitopes in theCryptococcus neoformanscapsule

(2009) Marcellene A. Gates-Hollingsworth et al.   MOLECULAR MICROBIOLOGY

TwoCDC42paralogues modulateCryptococcus neoformansthermotolerance and morphogenesis under host physiological conditions

(2009) Elizabeth R. Ballou et al.   MOLECULAR MICROBIOLOGY

Characterization of the PMT Gene Family in Cryptococcus neoformans

(2009) Sven D. Willger et al.   PLoS One

Capsule of Cryptococcus neoformans grows by enlargement of polysaccharide molecules

(2009) S. Frases et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The homologue of the Saccharomyces cerevisiae RIM9 gene is required for ambient pH signalling in Candida albicans

(2009) Muriel Cornet et al.   RESEARCH IN MICROBIOLOGY

Iron availability and infection

(2008) Eugene D. Weinberg   BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS

Systematic Genetic Analysis of Virulence in the Human Fungal Pathogen Cryptococcus neoformans

(2008) Oliver W. Liu et al.   CELL

Invasion ofCryptococcus neoformansinto human brain microvascular endothelial cells requires protein kinase C-α activation

(2008) Ambrose Jong et al.   CELLULAR MICROBIOLOGY

Capsule enlargement inCryptococcus neoformansconfers resistance to oxidative stress suggesting a mechanism for intracellular survival

(2008) Oscar Zaragoza et al.   CELLULAR MICROBIOLOGY

β1,2-Xylosyltransferase Cxt1p Is Solely Responsible for Xylose Incorporation intoCryptococcus neoformansGlycosphingolipids

(2008) Sherry A. Castle et al.   EUKARYOTIC CELL

UGE1andUGE2Regulate the UDP-Glucose/UDP-Galactose Equilibrium inCryptococcus neoformans

(2008) Frédérique Moyrand et al.   EUKARYOTIC CELL

The RGS Protein Crg2 Regulates Pheromone and Cyclic AMP Signaling inCryptococcus neoformans

(2008) Gui Shen et al.   EUKARYOTIC CELL

PKC1Is Essential for Protection against both Oxidative and Nitrosative Stresses, Cell Integrity, and Normal Manifestation of Virulence Factors in the Pathogenic FungusCryptococcus neoformans

(2008) Kimberly J. Gerik et al.   EUKARYOTIC CELL

Candida albicansFerric Reductases Are Differentially Regulated in Response to Distinct Forms of Iron Limitation by the Rim101 and CBF Transcription Factors

(2008) Yong-Un Baek et al.   EUKARYOTIC CELL

Cryptococcal Xylosyltransferase 1 (Cxt1p) fromCryptococcus neoformansPlays a Direct Role in the Synthesis of Capsule Polysaccharides

(2008) J. Stacey Klutts et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Ambient pH signalling in the yeast Yarrowia lipolytica involves YlRim23p/PalC, which interacts with Snf7p/Vps32p, but does not require the long C terminus of YlRim9p/PalI

(2008) S. Blanchin-Roland et al.   MICROBIOLOGY-SGM

The RGS protein Crg2 regulates both pheromone and cAMP signalling inCryptococcus neoformans

(2008) Chaoyang Xue et al.   MOLECULAR MICROBIOLOGY

Iron Source Preference and Regulation of Iron Uptake in Cryptococcus neoformans

(2008) Won Hee Jung et al.   PLoS Pathogens

Histoplasma Requires SID1, a Member of an Iron-Regulated Siderophore Gene Cluster, for Host Colonization

(2008) Lena H. Hwang et al.   PLoS Pathogens